Upstream Bio, Inc. (UPB) — Institutional Holders, Q2 2026 (page 2)
150 institutional investment managers reported a UPB position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $349.9M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 101 to 150. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
UPB 13F holders ranked 101–150 of 150
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 101 | Engineers Gate Manager#101 · 12,491 sh | 12,491 | $86.4K | <0.01% | New |
| 102 | STRS OHIO#102 · 12,000 sh | 12,000 | $83.0K | <0.01% | +22.4% |
| 103 | CANADA PENSION PLAN INVESTMENT BOARD#103 · 11,500 sh | 11,500 | $79.6K | 0.00% | New |
| 104 | HSBC PLC#104 · 10,793 sh | 10,793 | $77.6K | 0.00% | -98.3% |
| 105 | WEALTH ENHANCEMENT ADVISORY SERVICES#105 · 10,017 sh | 10,017 | $75.4K | — | New |
| 106 | PRELUDE CAPITAL MANAGEMENT#106 · 10,550 sh | 10,550 | $73.0K | <0.01% | New |
| 107 | AMERIPRISE FINANCIAL#107 · 10,487 sh | 10,487 | $72.6K | 0.00% | New |
| 108 | Police & Firemen's Retirement System of New Jersey#108 · 9,456 sh | 9,456 | $65.4K | <0.01% | 0.0% |
| 109 | China Universal Asset Management , Ltd.#109 · 8,661 sh | 8,661 | $59.9K | <0.01% | -9.7% |
| 110 | KLP KAPITALFORVALTNING AS#110 · 5,900 sh | 5,900 | $40.8K | <0.01% | 0.0% |
| 111 | NEW YORK STATE COMMON RETIREMENT FUND#111 · 5,200 sh | 5,200 | $36.0K | 0.00% | +5100.0% |
| 112 | Persistent Asset Partners Ltd#112 · 4,855 sh | 4,855 | $33.6K | 0.01% | -11.6% |
| 113 | Tower Research Capital (TRC)#113 · 4,788 sh | 4,788 | $33.1K | <0.01% | +236.0% |
| 114 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO#114 · 4,700 sh | 4,700 | $32.5K | <0.01% | New |
| 115 | NISA INVESTMENT ADVISORS#115 · 4,278 sh | 4,278 | $29.6K | — | -78.1% |
| 116 | Vanguard Investments Australia, Ltd.#116 · 4,096 sh | 4,096 | $28.3K | <0.01% | 0.0% |
| 117 | Wellington Grp#117 · 3,000 sh | 3,000 | $27.0K | <0.01% | 0.0% |
| 118 | Ameritas Investment Partners#118 · 2,741 sh | 2,741 | $19.0K | <0.01% | 0.0% |
| 119 | Integrated Wealth Concepts#119 · 2,479 sh | 2,479 | $17.2K | <0.01% | New |
| 120 | Mirae Asset Global Investments , Ltd.#120 · 2,434 sh | 2,434 | $16.8K | 0.00% | -13.7% |
| 121 | Global Retirement Partners#121 · 1,870 sh | 1,870 | $12.9K | <0.01% | — |
| 122 | SRS Capital Advisors#122 · 1,771 sh | 1,771 | $12.3K | <0.01% | +2200.0% |
| 123 | GAMMA Investing#123 · 1,164 sh | 1,164 | $8.1K | — | +62.8% |
| 124 | GF FUND MANAGEMENT LTD.#124 · 1,145 sh | 1,145 | $7.9K | — | -4.8% |
| 125 | ROYAL BANK OF CANADA#125 · 1,091 sh | 1,091 | $7.0K | 0.00% | New |
| 126 | Zurcher Kantonalbank (Zurich Cantonalbank)#126 · 965 sh | 965 | $6.7K | 0.00% | +102.3% |
| 127 | Quarry#127 · 893 sh | 893 | $6.2K | <0.01% | New |
| 128 | Allworth Financial#128 · 778 sh | 778 | $5.4K | 0.00% | +195.8% |
| 129 | Rockefeller Capital Management L.P.#129 · 738 sh | 738 | $5.1K | 0.00% | 0.0% |
| 130 | Sterling Capital Management#130 · 710 sh | 710 | $4.9K | — | -35.1% |
| 131 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#131 · 588 sh | 588 | $4.1K | 0.00% | 0.0% |
| 132 | PNC FINANCIAL SERVICES GROUP#132 · 387 sh | 387 | $2.7K | 0.00% | New |
| 133 | Farther Finance Advisors#133 · 353 sh | 353 | $2.4K | — | +335.8% |
| 134 | ROTHSCHILD INVESTMENT#134 · 287 sh | 287 | $2.0K | <0.01% | +370.5% |
| 135 | EverSource Wealth Advisors#135 · 272 sh | 272 | $1.9K | <0.01% | +40.9% |
| 136 | US BANCORP \DE\#136 · 264 sh | 264 | $1.8K | 0.00% | -55.3% |
| 137 | IFP Advisors#137 · 242 sh | 242 | $1.7K | — | New |
| 138 | Physician Wealth Advisors#138 · 160 sh | 160 | $1.1K | — | New |
| 139 | Essential Partners#139 · 146 sh | 146 | $1.0K | — | -63.7% |
| 140 | N.E.W. Advisory Services#140 · 120 sh | 120 | $830.00 | <0.01% | 0.0% |
| 141 | SJS Investment Consulting#141 · 76 sh | 76 | $526.00 | — | +3700.0% |
| 142 | Silver Grove Financial Group#142 · 28 sh | 28 | $194.00 | <0.01% | New |
| 143 | SIMPLEX TRADING#143 · 20 sh | 20 | $138.00 | 0.00% | New |
| 144 | OSAIC#144 · 19 sh | 19 | $131.00 | 0.00% | -95.1% |
| 145 | Clearstead Advisors#145 · 15 sh | 15 | $105.00 | 0.00% | New |
| 146 | JPL Wealth Management#146 · 14 sh | 14 | $97.00 | 0.00% | New |
| 147 | Freestone Grove Partners#147 · 1 sh | 1 | $7.00 | 0.00% | 0.0% |
| 148 | NATIONAL BANK OF CANADA#148 · 1 sh | 1 | $7.00 | 0.00% | New |
| 149 | Covestor Ltd#149 · 39 sh | 39 | $0.00 | 0.00% | +875.0% |
| 150 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM#150 · 38,634 sh | 38,634 | — | — | -2.6% |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.