Oruka Therapeutics, Inc. (ORKA) — Institutional Holders, Q2 2026
257 institutional investment managers reported a ORKA position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $7.0B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
ORKA in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- Capital World InvestorsNew · +3,401,639 sh+$323.7M
- FMRAdded · +1,626,242 sh+$154.8M
- RA CAPITAL MANAGEMENT, L.P.New · +1,554,597 sh+$148.0M
- BlackRockAdded · +1,463,094 sh+$139.2M
- Bellevue Group AGAdded · +1,150,182 sh+$109.5M
Biggest sellers
- VIKING GLOBAL INVESTORSTrimmed · -1,163,212 sh-$110.7M
- MERCER GLOBAL ADVISORSSold out · -802,470 sh-$76.4M
- SR ONE CAPITAL MANAGEMENTSold out · -430,330 sh-$41.0M
- Remedium Capital PartnersTrimmed · -323,454 sh-$30.8M
- Woodline PartnersTrimmed · -289,635 sh-$27.6M
ORKA 13F holders ranked 1–100 of 257
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | FMR#1 · 9,057,645 sh | 9,057,645 | $862.0M | 0.04% | +21.9% |
| 2 | BlackRock#2 · 4,990,181 sh | 4,990,181 | $474.9M | <0.01% | +41.5% |
| 3 | VR Adviser#3 · 4,148,428 sh | 4,148,428 | $394.8M | 11.97% | 0.0% |
| 4 | Fairmount Funds Management#4 · 3,705,262 sh | 3,705,262 | $352.6M | 23.31% | 0.0% |
| 5 | Capital World Investors#5 · 3,401,639 sh | 3,401,639 | $323.7M | 0.04% | New |
| 6 | RTW INVESTMENTS#6 · 3,139,030 sh | 3,139,030 | $298.7M | 2.55% | +52.5% |
| 7 | STATE STREET#7 · 2,673,090 sh | 2,673,090 | $254.4M | <0.01% | +65.7% |
| 8 | VANGUARD CAPITAL MANAGEMENT#8 · 2,360,971 sh | 2,360,971 | $224.7M | <0.01% | +27.0% |
| 9 | Paradigm Biocapital Advisors#9 · 2,144,526 sh | 2,144,526 | $204.1M | 3.82% | -7.6% |
| 10 | Deep Track Capital#10 · 1,926,000 sh | 1,926,000 | $183.3M | 2.67% | -5.3% |
| 11 | Bellevue Group AG#11 · 1,657,190 sh | 1,657,190 | $157.7M | 3.32% | +226.9% |
| 12 | FRANKLIN RESOURCES#12 · 1,621,451 sh | 1,621,451 | $154.3M | 0.03% | +61.5% |
| 13 | Remedium Capital Partners#13 · 1,565,661 sh | 1,565,661 | $149.0M | 32.99% | -17.1% |
| 14 | RA CAPITAL MANAGEMENT, L.P.#14 · 1,554,597 sh | 1,554,597 | $148.0M | 1.29% | New |
| 15 | VIKING GLOBAL INVESTORS#15 · 1,503,478 sh | 1,503,478 | $143.1M | 0.41% | -43.6% |
| 16 | GEODE CAPITAL MANAGEMENT#16 · 1,429,954 sh | 1,429,954 | $136.1M | <0.01% | +49.8% |
| 17 | Jupiter Topco#17 · 1,375,844 sh | 1,375,844 | $131.0M | 0.05% | — |
| 18 | PERCEPTIVE ADVISORS#18 · 1,345,063 sh | 1,345,063 | $128.0M | 1.92% | -3.6% |
| 19 | Polar Capital Plc#19 · 1,228,609 sh | 1,228,609 | $116.9M | 0.28% | +17.3% |
| 20 | CITADEL ADVISORS#20 · 1,119,011 sh | 1,119,011 | $106.5M | 0.01% | +11.1% |
| 21 | T. Rowe Price Investment Management#21 · 1,103,743 sh | 1,103,743 | $105.0M | 0.07% | New |
| 22 | BNP PARIBAS FINANCIAL MARKETS#22 · 1,079,015 sh | 1,079,015 | $102.7M | 0.04% | +9773.9% |
| 23 | PRICE T ROWE ASSOCIATES#23 · 838,603 sh | 838,603 | $79.8M | <0.01% | +15.3% |
| 24 | Avidity Partners Management#24 · 760,424 sh | 760,424 | $72.4M | 11.59% | 0.0% |
| 25 | SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT#25 · 658,301 sh | 658,301 | $62.7M | 1.10% | New |
| 26 | abrdn plc#26 · 646,943 sh | 646,943 | $61.6M | 0.09% | +754.8% |
| 27 | UBS Group AG#27 · 639,363 sh | 639,363 | $60.8M | <0.01% | +201.2% |
| 28 | JPMORGAN CHASE#28 · 655,027 sh | 655,027 | $60.7M | <0.01% | +2795.8% |
| 29 | WESTFIELD CAPITAL MANAGEMENT#29 · 631,433 sh | 631,433 | $60.1M | 0.20% | +101.7% |
| 30 | Pictet Asset Management Holding SA#30 · 619,076 sh | 619,076 | $58.9M | 0.06% | New |
| 31 | Affinity Asset Advisors#31 · 590,000 sh | 590,000 | $56.2M | 2.54% | +18.1% |
| 32 | VANGUARD PORTFOLIO MANAGEMENT#32 · 582,409 sh | 582,409 | $55.4M | <0.01% | +66.0% |
| 33 | Cormorant Asset Management#33 · 533,340 sh | 533,340 | $50.8M | 2.60% | 0.0% |
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT#34 · 433,405 sh | 433,405 | $41.2M | <0.01% | +34.6% |
| 35 | NORTHERN#35 · 428,891 sh | 428,891 | $40.8M | <0.01% | +43.4% |
| 36 | VOYA INVESTMENT MANAGEMENT#36 · 401,149 sh | 401,149 | $38.2M | 0.03% | +502.3% |
| 37 | LORD, ABBETT#37 · 390,064 sh | 390,064 | $37.1M | 0.11% | New |
| 38 | VANGUARD FIDUCIARY#38 · 365,630 sh | 365,630 | $34.8M | <0.01% | +42.2% |
| 39 | MASSACHUSETTS FINANCIAL SERVICES#39 · 364,102 sh | 364,102 | $34.7M | 0.01% | New |
| 40 | Synergy Financial Management#40 · 356,301 sh | 356,301 | $33.9M | 3.20% | -25.2% |
| 41 | ADAGE CAPITAL PARTNERS GP, L.L.C.#41 · 355,003 sh | 355,003 | $33.8M | 0.05% | +86.8% |
| 42 | BANK OF AMERICA#42 · 352,824 sh | 352,824 | $33.6M | <0.01% | +252.5% |
| 43 | SILVERARC CAPITAL MANAGEMENT#43 · 352,802 sh | 352,802 | $33.6M | 3.49% | +133.8% |
| 44 | Candriam S.C.A.#44 · 352,716 sh | 352,716 | $33.5M | 0.15% | -14.2% |
| 45 | Holocene Advisors#45 · 305,951 sh | 305,951 | $29.1M | 0.07% | +64.9% |
| 46 | JENNISON ASSOCIATES#46 · 299,257 sh | 299,257 | $28.5M | 0.02% | +69.4% |
| 47 | Woodline Partners#47 · 285,247 sh | 285,247 | $27.1M | 0.08% | -50.4% |
| 48 | BRAIDWELL#48 · 278,164 sh | 278,164 | $26.5M | 0.98% | New |
| 49 | Siren, L.L.C.#49 · 250,000 sh | 250,000 | $23.8M | 0.48% | New |
| 50 | Nuveen#50 · 249,267 sh | 249,267 | $23.7M | <0.01% | +186.7% |
| 51 | EVENTIDE ASSET MANAGEMENT#51 · 240,000 sh | 240,000 | $22.8M | 0.31% | New |
| 52 | Blackstone#52 · 237,108 sh | 237,108 | $22.6M | 0.06% | New |
| 53 | NOMURA ASSET MANAGEMENT INTERNATIONAL#53 · 219,039 sh | 219,039 | $20.8M | 0.03% | New |
| 54 | SEB Asset Management AB#54 · 196,753 sh | 196,753 | $18.7M | 0.07% | New |
| 55 | DEUTSCHE BANK AG\#55 · 195,204 sh | 195,204 | $18.6M | <0.01% | +38.7% |
| 56 | GREAT POINT PARTNERS#56 · 183,330 sh | 183,330 | $17.4M | 3.30% | 0.0% |
| 57 | GOLDMAN SACHS GROUP#57 · 179,439 sh | 179,439 | $17.1M | <0.01% | -27.3% |
| 58 | Sio Capital Management#58 · 177,118 sh | 177,118 | $16.9M | 2.79% | +33.7% |
| 59 | Handelsbanken Fonder AB#59 · 160,900 sh | 160,900 | $15.3M | 0.04% | New |
| 60 | PFM Health Sciences#60 · 158,825 sh | 158,825 | $15.1M | 1.30% | -8.7% |
| 61 | First Turn Management#61 · 155,343 sh | 155,343 | $14.8M | 1.58% | New |
| 62 | ExodusPoint Capital Management#62 · 148,212 sh | 148,212 | $14.1M | 0.09% | +46.2% |
| 63 | Bank of New York Mellon#63 · 140,870 sh | 140,870 | $13.4M | <0.01% | +31.8% |
| 64 | Invesco Ltd.#64 · 124,658 sh | 124,658 | $11.9M | <0.01% | +28.5% |
| 65 | VICTORY CAPITAL MANAGEMENT#65 · 124,278 sh | 124,278 | $11.8M | <0.01% | +2556.6% |
| 66 | WELLINGTON MANAGEMENT GROUP LLP#66 · 119,601 sh | 119,601 | $11.4M | <0.01% | -1.3% |
| 67 | StemPoint Capital#67 · 116,461 sh | 116,461 | $11.1M | 1.91% | New |
| 68 | Parkman Healthcare Partners#68 · 113,188 sh | 113,188 | $10.8M | 1.10% | New |
| 69 | DIMENSIONAL FUND ADVISORS#69 · 113,176 sh | 113,176 | $10.8M | <0.01% | +0.1% |
| 70 | Russell Investments Group, Ltd.#70 · 112,943 sh | 112,943 | $10.7M | <0.01% | +148.5% |
| 71 | APIS CAPITAL ADVISORS#71 · 112,000 sh | 112,000 | $10.7M | 1.04% | New |
| 72 | SEVEN GRAND MANAGERS#72 · 110,000 sh | 110,000 | $10.5M | 0.42% | New |
| 73 | KENNEDY CAPITAL MANAGEMENT#73 · 106,863 sh | 106,863 | $10.2M | 0.18% | -15.4% |
| 74 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#74 · 104,310 sh | 104,310 | $9.9M | <0.01% | +517.1% |
| 75 | TD ASSET MANAGEMENT#75 · 102,944 sh | 102,944 | $9.8M | <0.01% | +36.0% |
| 76 | MOODY ALDRICH PARTNERS#76 · 101,411 sh | 101,411 | $9.7M | 1.73% | -24.9% |
| 77 | Atika Capital Management#77 · 100,000 sh | 100,000 | $9.5M | 0.63% | -56.5% |
| 78 | TORONTO DOMINION BANK#78 · 89,837 sh | 89,837 | $8.5M | <0.01% | New |
| 79 | Alyeska Investment Group, L.P.#79 · 87,744 sh | 87,744 | $8.4M | 0.02% | -52.5% |
| 80 | PRUDENTIAL FINANCIAL#80 · 85,895 sh | 85,895 | $8.2M | <0.01% | +1322.1% |
| 81 | Rhenman & Partners Asset Management AB#81 · 80,000 sh | 80,000 | $7.6M | 0.72% | New |
| 82 | MORGAN STANLEY#82 · 76,360 sh | 76,360 | $7.3M | <0.01% | -56.5% |
| 83 | B Group#83 · 75,000 sh | 75,000 | $7.1M | 3.35% | 0.0% |
| 84 | BARCLAYS PLC#84 · 74,762 sh | 74,762 | $7.1M | <0.01% | -12.8% |
| 85 | AMERIPRISE FINANCIAL#85 · 72,734 sh | 72,734 | $6.9M | <0.01% | New |
| 86 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#86 · 68,421 sh | 68,421 | $6.5M | <0.01% | -5.7% |
| 87 | Fisher Asset Management#87 · 67,874 sh | 67,874 | $6.5M | <0.01% | New |
| 88 | Ensign Peak Advisors#88 · 67,668 sh | 67,668 | $6.4M | 0.01% | -14.8% |
| 89 | CITIGROUP#89 · 67,101 sh | 67,101 | $6.4M | <0.01% | +546.0% |
| 90 | Secure Asset Management#90 · 65,899 sh | 65,899 | $6.3M | — | -9.0% |
| 91 | Swiss National Bank#91 · 63,000 sh | 63,000 | $6.0M | <0.01% | +46.5% |
| 92 | ALPS ADVISORS#92 · 61,014 sh | 61,014 | $5.8M | 0.03% | +54.8% |
| 93 | RHUMBLINE ADVISERS#93 · 60,784 sh | 60,784 | $5.8M | <0.01% | +31.1% |
| 94 | Informed Momentum#94 · 59,014 sh | 59,014 | $5.6M | 0.50% | -1.6% |
| 95 | HealthInvest Partners AB#95 · 54,886 sh | 54,886 | $5.2M | 1.41% | New |
| 96 | WELLS FARGO & COMPANY#96 · 51,924 sh | 51,924 | $4.9M | <0.01% | +250.1% |
| 97 | Granahan Investment Management#97 · 51,038 sh | 51,038 | $4.9M | 0.17% | New |
| 98 | Ghisallo Capital Management#98 · 50,000 sh | 50,000 | $4.8M | 0.09% | New |
| 99 | Burkehill Global Management#99 · 50,000 sh | 50,000 | $4.8M | 0.17% | New |
| 100 | Trexquant Investment#100 · 49,616 sh | 49,616 | $4.7M | 0.03% | New |
Funds that sold out of ORKA in Q2 2026 (27)
Held ORKA at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| MERCER GLOBAL ADVISORS802,470 sh | 802,470 | $39.4M |
| SR ONE CAPITAL MANAGEMENT430,330 sh | 430,330 | $21.1M |
| Ikarian Capital242,021 sh | 242,021 | $11.9M |
| Cable Car Capital200,000 sh | 200,000 | $9.8M |
| Jones Hill Capital140,843 sh | 140,843 | $6.9M |
| Longaeva Partners L.P.136,884 sh | 136,884 | $6.7M |
| Kalehua Capital Management118,524 sh | 118,524 | $5.8M |
| BOOTHBAY FUND MANAGEMENT67,481 sh | 67,481 | $3.3M |
| SUPERSTRING CAPITAL MANAGEMENT63,591 sh | 63,591 | $3.1M |
| FRED ALGER MANAGEMENT43,841 sh | 43,841 | $2.2M |
| Y-Intercept (Hong Kong) Ltd36,912 sh | 36,912 | $1.8M |
| Squarepoint Ops24,463 sh | 24,463 | $1.2M |
| TWO SIGMA INVESTMENTS19,364 sh | 19,364 | $949.8K |
| Resolute Capital Asset Partners12,500 sh | 12,500 | $613.1K |
| Abacus Wealth Partners7,802 sh | 7,802 | $382.7K |
| Toroso Investments6,546 sh | 6,546 | $321.1K |
| Archer Investment6,546 sh | 6,546 | $321.1K |
| EntryPoint Capital6,120 sh | 6,120 | $300.2K |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C.5,855 sh | 5,855 | $287.2K |
| Soleus Capital Management, L.P.5,000 sh | 5,000 | $245.3K |
| VARCOV4,673 sh | 4,673 | $229.2K |
| SIMPLEX TRADING2,463 sh | 2,463 | $120.8K |
| Caitong International Asset Management , Ltd910 sh | 910 | $44.6K |
| True Wealth Design26 sh | 26 | $1.3K |
| Ameritas Advisory Services11 sh | 11 | $540.00 |
| Golden State Equity Partners8 sh | 8 | $392.00 |
| MAI Capital Management1 sh | 1 | $50.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.