Milestone Pharmaceuticals Inc. (MIST) — Institutional Holders, Q2 2026
78 institutional investment managers reported a MIST position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $66.4M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
MIST in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- Point72 Asset Management, L.P.Added · +4,325,455 sh+$5.8M
- Propel Bio ManagementAdded · +3,311,269 sh+$4.4M
- Simplify Asset ManagementAdded · +1,842,974 sh+$2.5M
- MILLENNIUM MANAGEMENTAdded · +1,597,894 sh+$2.1M
- RTW INVESTMENTSAdded · +1,502,335 sh+$2.0M
Biggest sellers
- GOLDMAN SACHS GROUPSold out · -2,000,025 sh-$2.7M
- BALYASNY ASSET MANAGEMENT L.P.Trimmed · -630,827 sh-$845.3K
- TWO SIGMA INVESTMENTSTrimmed · -277,161 sh-$371.4K
- CITADEL ADVISORSTrimmed · -163,809 sh-$219.5K
- SUSQUEHANNA INTERNATIONAL GROUP, LLPTrimmed · -159,151 sh-$213.3K
MIST 13F holders ranked 1–78 of 78
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | Pavaki Capital Management#1 · 9,067,848 sh | 9,067,848 | $12.2M | — | +0.1% |
| 2 | RTW INVESTMENTS#2 · 7,833,336 sh | 7,833,336 | $10.5M | 0.09% | +23.7% |
| 3 | Propel Bio Management#3 · 7,429,590 sh | 7,429,590 | $10.0M | 5.21% | +80.4% |
| 4 | Point72 Asset Management, L.P.#4 · 5,411,138 sh | 5,411,138 | $7.3M | <0.01% | +398.4% |
| 5 | Simplify Asset Management#5 · 3,349,379 sh | 3,349,379 | $4.5M | 0.06% | +122.3% |
| 6 | MILLENNIUM MANAGEMENT#6 · 3,142,219 sh | 3,142,219 | $4.2M | <0.01% | +103.5% |
| 7 | TWO SIGMA INVESTMENTS#7 · 2,040,015 sh | 2,040,015 | $2.7M | <0.01% | -12.0% |
| 8 | MARSHALL WACE, LLP#8 · 1,797,695 sh | 1,797,695 | $2.4M | <0.01% | -7.6% |
| 9 | Kalehua Capital Management#9 · 1,269,237 sh | 1,269,237 | $1.7M | 1.22% | New |
| 10 | Lion Point Capital#10 · 820,000 sh | 820,000 | $1.1M | 5.26% | 0.0% |
| 11 | TORONTO DOMINION BANK#11 · 750,000 sh | 750,000 | $1.0M | <0.01% | 0.0% |
| 12 | Boxer Capital Management#12 · 666,666 sh | 666,666 | $893.3K | 0.07% | 0.0% |
| 13 | AMERIPRISE FINANCIAL#13 · 666,666 sh | 666,666 | $893.3K | <0.01% | New |
| 14 | MORGAN STANLEY#14 · 635,211 sh | 635,211 | $851.2K | 0.00% | -12.3% |
| 15 | UBS Group AG#15 · 465,403 sh | 465,403 | $623.6K | <0.01% | -6.0% |
| 16 | BOOTHBAY FUND MANAGEMENT#16 · 462,669 sh | 462,669 | $620.0K | <0.01% | +174.3% |
| 17 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#17 · 359,895 sh | 359,895 | $482.3K | 0.00% | -30.7% |
| 18 | Aptus Capital Advisors#18 · 339,450 sh | 339,450 | $454.9K | <0.01% | +21.1% |
| 19 | GUARDIAN WEALTH ADVISORS, / NC#19 · 339,450 sh | 339,450 | $454.9K | 0.03% | +21.1% |
| 20 | Seven Fleet Capital Management#20 · 270,233 sh | 270,233 | $362.1K | 0.06% | -18.9% |
| 21 | Squarepoint Ops#21 · 231,824 sh | 231,824 | $310.6K | <0.01% | -31.2% |
| 22 | LPL Financial#22 · 220,873 sh | 220,873 | $296.0K | <0.01% | +14.2% |
| 23 | BALYASNY ASSET MANAGEMENT L.P.#23 · 220,498 sh | 220,498 | $295.5K | <0.01% | -74.1% |
| 24 | BNP PARIBAS FINANCIAL MARKETS#24 · 173,704 sh | 173,704 | $232.8K | <0.01% | -1.6% |
| 25 | TRU INDEPENDENCE ASSET MANAGEMENT 2#25 · 150,000 sh | 150,000 | $201.0K | 0.11% | +50.0% |
| 26 | Wealthspire Advisors#26 · 140,629 sh | 140,629 | $188.4K | <0.01% | +1223.1% |
| 27 | Valeo Financial Advisors#27 · 130,699 sh | 130,699 | $175.1K | — | 0.0% |
| 28 | ADAR1 Capital Management#28 · 100,000 sh | 100,000 | $134.0K | <0.01% | 0.0% |
| 29 | Cascades Capital Asset Management#29 · 83,610 sh | 83,610 | $112.0K | 0.04% | New |
| 30 | Quadrature Capital Ltd#30 · 64,661 sh | 64,661 | $86.6K | <0.01% | -56.6% |
| 31 | JANE STREET GROUP#31 · 57,787 sh | 57,787 | $77.4K | 0.00% | -63.8% |
| 32 | SIMPLEX TRADING#32 · 54,171 sh | 54,171 | $72.6K | 0.00% | -63.7% |
| 33 | Bay Rivers Group#33 · 46,633 sh | 46,633 | $62.5K | 0.02% | +55.9% |
| 34 | SG Americas Securities#34 · 45,574 sh | 45,574 | $61.0K | 0.00% | +7.2% |
| 35 | GEODE CAPITAL MANAGEMENT#35 · 40,789 sh | 40,789 | $54.7K | 0.00% | 0.0% |
| 36 | October Effect Ltd#36 · 40,000 sh | 40,000 | $53.6K | — | -23.0% |
| 37 | Focus Partners Wealth#37 · 36,000 sh | 36,000 | $48.2K | 0.00% | 0.0% |
| 38 | CITADEL ADVISORS#38 · 32,887 sh | 32,887 | $44.1K | 0.00% | -83.3% |
| 39 | RAYMOND JAMES FINANCIAL#39 · 30,070 sh | 30,070 | $40.3K | 0.00% | +13.0% |
| 40 | Federation des caisses Desjardins du Quebec#40 · 29,781 sh | 29,781 | $39.9K | <0.01% | 0.0% |
| 41 | Mariner#41 · 27,830 sh | 27,830 | $37.2K | 0.00% | -9.7% |
| 42 | XTX Topco Ltd#42 · 26,317 sh | 26,317 | $35.3K | <0.01% | -78.2% |
| 43 | WELCH & FORBES#43 · 25,000 sh | 25,000 | $33.5K | <0.01% | 0.0% |
| 44 | Tower Research Capital (TRC)#44 · 24,185 sh | 24,185 | $32.4K | <0.01% | +164.4% |
| 45 | NATIONAL BANK OF CANADA#45 · 23,500 sh | 23,500 | $31.5K | 0.00% | 0.0% |
| 46 | Exit Wealth Advisors#46 · 22,692 sh | 22,692 | $30.4K | 0.01% | +51.3% |
| 47 | STATE STREET#47 · 22,564 sh | 22,564 | $30.2K | 0.00% | +1.0% |
| 48 | HighTower Advisors#48 · 20,000 sh | 20,000 | $26.8K | 0.00% | +100.0% |
| 49 | Stephenson & Company#49 · 20,000 sh | 20,000 | $26.8K | 0.01% | 0.0% |
| 50 | Taylor Financial Group#50 · 20,000 sh | 20,000 | $26.8K | 0.01% | +33.3% |
| 51 | TWO SIGMA SECURITIES#51 · 16,745 sh | 16,745 | $22.4K | <0.01% | New |
| 52 | Cetera Investment Advisers#52 · 16,368 sh | 16,368 | $21.9K | 0.00% | +11.3% |
| 53 | Pathstone#53 · 15,500 sh | 15,500 | $20.8K | <0.01% | -9.0% |
| 54 | AE Wealth Management#54 · 15,000 sh | 15,000 | $20.1K | <0.01% | 0.0% |
| 55 | Vision Retirement#55 · 15,000 sh | 15,000 | $20.1K | <0.01% | 0.0% |
| 56 | JONES FINANCIAL COMPANIES LLLP#56 · 16,000 sh | 16,000 | $19.8K | 0.00% | 0.0% |
| 57 | EARNED WEALTH ADVISORS#57 · 14,756 sh | 14,756 | $19.8K | <0.01% | 0.0% |
| 58 | Bronte Capital Management Pty Ltd.#58 · 14,390 sh | 14,390 | $19.3K | <0.01% | +38.2% |
| 59 | WINTON GROUP Ltd#59 · 14,300 sh | 14,300 | $19.2K | <0.01% | New |
| 60 | Beta Wealth Group#60 · 14,127 sh | 14,127 | $18.9K | <0.01% | 0.0% |
| 61 | Strategic Family Wealth Counselors, L.L.C.#61 · 13,875 sh | 13,875 | $18.6K | <0.01% | 0.0% |
| 62 | Cambridge Investment Research Advisors#62 · 13,480 sh | 13,480 | $18.0K | 0.00% | -77.4% |
| 63 | Creative Planning#63 · 13,080 sh | 13,080 | $17.5K | 0.00% | -2.5% |
| 64 | Rockefeller Capital Management L.P.#64 · 12,500 sh | 12,500 | $16.8K | 0.00% | 0.0% |
| 65 | Safeguard Investment Advisory Group#65 · 12,406 sh | 12,406 | $16.6K | <0.01% | -50.5% |
| 66 | Virtu Financial#66 · 11,613 sh | 11,613 | $16.0K | <0.01% | New |
| 67 | Eaton Financial Company#67 · 10,250 sh | 10,250 | $13.7K | <0.01% | 0.0% |
| 68 | Secure Asset Management#68 · 10,000 sh | 10,000 | $13.4K | — | 0.0% |
| 69 | INTEGRAL INVESTMENT ADVISORS#69 · 10,000 sh | 10,000 | $13.4K | <0.01% | 0.0% |
| 70 | ROYAL BANK OF CANADA#70 · 6,698 sh | 6,698 | $9.0K | 0.00% | 0.0% |
| 71 | US BANCORP \DE\#71 · 3,200 sh | 3,200 | $4.3K | 0.00% | 0.0% |
| 72 | SRS Capital Advisors#72 · 3,053 sh | 3,053 | $4.1K | 0.00% | New |
| 73 | PNC FINANCIAL SERVICES GROUP#73 · 2,800 sh | 2,800 | $3.8K | 0.00% | +180.0% |
| 74 | Medallion Wealth Advisors#74 · 340 sh | 340 | $456.00 | <0.01% | 0.0% |
| 75 | Rialto Wealth Management#75 · 300 sh | 300 | $402.00 | <0.01% | 0.0% |
| 76 | GROUP ONE TRADING, L.P.#76 · 224 sh | 224 | $300.00 | 0.00% | -99.8% |
| 77 | Caitong International Asset Management , Ltd#77 · 94 sh | 94 | $126.00 | 0.00% | -94.6% |
| 78 | SBI Securities , Ltd.#78 · 6 sh | 6 | $8.00 | — | -45.5% |
Funds that sold out of MIST in Q2 2026 (13)
Held MIST at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| GOLDMAN SACHS GROUP2,000,025 sh | 2,000,025 | $2.4M |
| RENAISSANCE TECHNOLOGIES129,705 sh | 129,705 | $154.3K |
| HRT FINANCIAL62,256 sh | 62,256 | $74.0K |
| Invesco Ltd.41,356 sh | 41,356 | $49.2K |
| NORTHERN38,779 sh | 38,779 | $46.1K |
| GSA CAPITAL PARTNERS LLP26,893 sh | 26,893 | $32.0K |
| ACADIAN ASSET MANAGEMENT20,468 sh | 20,468 | $24.0K |
| SJS Investment Consulting15,000 sh | 15,000 | $17.9K |
| IMC-Chicago10,943 sh | 10,943 | $13.0K |
| Bayesian Capital Management10,015 sh | 10,015 | $11.9K |
| Ancora Advisors10,000 sh | 10,000 | $11.9K |
| Key Capital Management212 sh | 212 | $252.00 |
| Russell Investments Group, Ltd.125 sh | 125 | $149.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.