MADRIGAL PHARMACEUTICALS, INC. (MDGL) — Institutional Holders, Q2 2026

417 institutional investment managers reported a MDGL position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $12.7B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← MDGL stock profile

MDGL in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

143

Trimmed

131

Sold out

Biggest buyers

UBS Group AGAdded · +283,929 sh+$152.5M
JANE STREET GROUPAdded · +155,703 sh+$83.6M
Holocene AdvisorsNew · +152,924 sh+$82.1M
AMERIPRISE FINANCIALAdded · +133,024 sh+$71.4M
WELLINGTON MANAGEMENT GROUP LLPAdded · +130,756 sh+$70.2M

Biggest sellers

BlackRockTrimmed · -359,195 sh-$192.9M
ADAGE CAPITAL PARTNERS GP, L.L.C.Sold out · -185,331 sh-$99.5M
FMRTrimmed · -155,527 sh-$83.5M
PRICE T ROWE ASSOCIATESTrimmed · -140,884 sh-$75.6M
Point72 Asset Management, L.P.Trimmed · -88,481 sh-$47.5M

MDGL 13F holders ranked 1–100 of 417

Institutional investors reporting a position in MADRIGAL PHARMACEUTICALS, INC. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	BAKER BROS. ADVISORS#1 · 2,143,131 sh	2,143,131	$1.2B	5.77%	+0.1%
2	RTW INVESTMENTS#2 · 1,993,687 sh	1,993,687	$1.1B	9.14%	0.0%
3	Jupiter Topco#3 · 1,936,099 sh	1,936,099	$1.0B	0.42%	—
4	Avoro Capital Advisors#4 · 1,833,333 sh	1,833,333	$984.4M	8.84%	+0.8%
5	PAULSON#5 · 1,340,020 sh	1,340,020	$719.5M	27.94%	-3.7%
6	BlackRock#6 · 1,200,770 sh	1,200,770	$644.8M	<0.01%	-23.0%
7	VANGUARD CAPITAL MANAGEMENT#7 · 835,668 sh	835,668	$448.7M	<0.01%	+1.0%
8	WELLINGTON MANAGEMENT GROUP LLP#8 · 825,714 sh	825,714	$443.4M	0.08%	+18.8%
9	VANGUARD PORTFOLIO MANAGEMENT#9 · 781,731 sh	781,731	$419.8M	0.02%	-7.1%
10	STATE STREET#10 · 527,057 sh	527,057	$283.0M	<0.01%	-13.5%
11	CITADEL ADVISORS#11 · 507,233 sh	507,233	$272.4M	0.03%	+11.8%
12	UBS Group AG#12 · 401,708 sh	401,708	$215.7M	0.03%	+241.1%
13	GEODE CAPITAL MANAGEMENT#13 · 374,880 sh	374,880	$201.3M	0.01%	-17.8%
14	FMR#14 · 356,201 sh	356,201	$191.3M	<0.01%	-30.4%
15	WILLIAM BLAIR INVESTMENT MANAGEMENT#15 · 324,123 sh	324,123	$174.0M	0.52%	-4.8%
16	Invesco Ltd.#16 · 301,435 sh	301,435	$161.9M	0.01%	-8.5%
17	ARMISTICE CAPITAL#17 · 288,000 sh	288,000	$154.6M	1.89%	+8.9%
18	LORD, ABBETT#18 · 281,500 sh	281,500	$151.2M	0.43%	+16.0%
19	GOLDMAN SACHS GROUP#19 · 246,280 sh	246,280	$132.2M	0.01%	-11.2%
20	Polar Capital Plc#20 · 244,274 sh	244,274	$131.2M	0.31%	-15.6%
21	AMERIPRISE FINANCIAL#21 · 231,205 sh	231,205	$124.1M	0.03%	+135.5%
22	NORGES BANK#22 · 213,886 sh	213,886	$114.8M	0.01%	—
23	Artisan Partners Limited Partnership#23 · 210,205 sh	210,205	$112.9M	0.18%	+14.5%
24	Pictet Asset Management Holding SA#24 · 192,896 sh	192,896	$103.5M	0.10%	+3.0%
25	JANE STREET GROUP#25 · 191,541 sh	191,541	$102.8M	<0.01%	+434.5%
26	PRICE T ROWE ASSOCIATES#26 · 187,226 sh	187,226	$100.5M	0.01%	-42.9%
27	ALLIANCEBERNSTEIN L.P.#27 · 189,458 sh	189,458	$99.2M	0.03%	+51.0%
28	CHARLES SCHWAB INVESTMENT MANAGEMENT#28 · 184,324 sh	184,324	$99.0M	0.01%	-14.9%
29	TORONTO DOMINION BANK#29 · 181,432 sh	181,432	$97.4M	0.11%	+39.1%
30	Rock Springs Capital Management#30 · 174,999 sh	174,999	$94.0M	4.59%	+2.3%
31	Hood River Capital Management#31 · 169,084 sh	169,084	$90.8M	0.66%	-32.2%
32	Holocene Advisors#32 · 152,924 sh	152,924	$82.1M	0.18%	New
33	SUSQUEHANNA INTERNATIONAL GROUP, LLP#33 · 148,610 sh	148,610	$79.8M	<0.01%	+568.9%
34	MORGAN STANLEY#34 · 139,009 sh	139,009	$74.6M	<0.01%	-27.3%
35	Point72 Asset Management, L.P.#35 · 137,029 sh	137,029	$73.6M	0.08%	-39.2%
36	BANK OF AMERICA#36 · 134,036 sh	134,036	$72.0M	<0.01%	-29.3%
37	Bank of New York Mellon#37 · 128,520 sh	128,520	$69.0M	0.01%	-5.4%
38	Woodline Partners#38 · 125,899 sh	125,899	$67.6M	0.21%	0.0%
39	Assenagon Asset Management S.A.#39 · 124,214 sh	124,214	$66.7M	—	+674.7%
40	VANGUARD FIDUCIARY#40 · 121,583 sh	121,583	$65.3M	0.01%	-5.1%
41	Clearbridge Investments#41 · 109,325 sh	109,325	$58.7M	0.05%	+347.2%
42	Erste Asset Management GmbH#42 · 110,210 sh	110,210	$58.1M	0.45%	-31.2%
43	MARSHALL WACE, LLP#43 · 101,859 sh	101,859	$54.7M	0.04%	+365.1%
44	Fiera Capital#44 · 99,857 sh	99,857	$53.6M	0.19%	-42.6%
45	AMERICAN CENTURY COMPANIES#45 · 99,396 sh	99,396	$53.4M	0.02%	-39.4%
46	NORTHERN#46 · 98,510 sh	98,510	$52.9M	<0.01%	-34.0%
47	NEW YORK STATE COMMON RETIREMENT FUND#47 · 94,743 sh	94,743	$50.9M	0.06%	+26.1%
48	WESTFIELD CAPITAL MANAGEMENT#48 · 93,931 sh	93,931	$50.4M	0.16%	-0.9%
49	HRT FINANCIAL#49 · 84,634 sh	84,634	$45.4M	0.11%	New
50	DEUTSCHE BANK AG\#50 · 83,916 sh	83,916	$45.1M	0.01%	-14.4%
51	MILLENNIUM MANAGEMENT#51 · 81,196 sh	81,196	$43.6M	0.02%	+98.8%
52	ALKEON CAPITAL MANAGEMENT#52 · 80,000 sh	80,000	$43.0M	0.06%	0.0%
53	BALYASNY ASSET MANAGEMENT L.P.#53 · 79,011 sh	79,011	$42.4M	0.05%	New
54	DRIEHAUS CAPITAL MANAGEMENT#54 · 78,094 sh	78,094	$41.9M	0.24%	-29.6%
55	Candriam S.C.A.#55 · 72,121 sh	72,121	$38.7M	0.17%	-15.1%
56	Tri Locum Partners#56 · 68,273 sh	68,273	$36.7M	4.51%	-33.9%
57	Vestal Point Capital#57 · 65,000 sh	65,000	$34.9M	0.82%	+106.6%
58	Allspring Global Investments#58 · 67,668 sh	67,668	$34.8M	0.05%	+5548.4%
59	VOYA INVESTMENT MANAGEMENT#59 · 61,202 sh	61,202	$32.9M	0.03%	+2.1%
60	BNP PARIBAS FINANCIAL MARKETS#60 · 57,998 sh	57,998	$31.1M	0.01%	+1.4%
61	Jones Hill Capital#61 · 52,545 sh	52,545	$28.2M	6.00%	New
62	EULAV Asset Management#62 · 52,000 sh	52,000	$27.9M	—	+6.1%
63	SCHRODER INVESTMENT MANAGEMENT GROUP#63 · 51,630 sh	51,630	$27.2M	0.02%	+29.6%
64	Russell Investments Group, Ltd.#64 · 49,294 sh	49,294	$26.5M	0.02%	+10.8%
65	RENAISSANCE TECHNOLOGIES#65 · 45,942 sh	45,942	$24.7M	0.03%	-36.1%
66	Affinity Asset Advisors#66 · 40,000 sh	40,000	$21.5M	0.97%	-27.3%
67	CITIGROUP#67 · 37,255 sh	37,255	$20.0M	<0.01%	+45.6%
68	D. E. Shaw#68 · 35,071 sh	35,071	$18.8M	<0.01%	+16.4%
69	Mirae Asset Global Investments , Ltd.#69 · 33,420 sh	33,420	$17.9M	0.03%	-18.3%
70	Nuveen#70 · 32,631 sh	32,631	$17.5M	<0.01%	-47.4%
71	SEGALL BRYANT & HAMILL#71 · 32,444 sh	32,444	$17.4M	0.21%	New
72	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#72 · 32,403 sh	32,403	$17.4M	<0.01%	+36.2%
73	BNP Paribas Asset Management Holding S.A.#73 · 31,998 sh	31,998	$17.2M	0.02%	-2.7%
74	GROUPAMA ASSET MANAGMENT#74 · 30,941 sh	30,941	$16.6M	0.21%	-12.2%
75	Swiss National Bank#75 · 29,940 sh	29,940	$16.1M	<0.01%	+2.5%
76	JPMORGAN CHASE#76 · 29,473 sh	29,473	$16.0M	<0.01%	-18.8%
77	PFM Health Sciences#77 · 29,313 sh	29,313	$15.7M	1.35%	-14.2%
78	CANADA PENSION PLAN INVESTMENT BOARD#78 · 29,080 sh	29,080	$15.6M	<0.01%	+137.2%
79	Rockefeller Capital Management L.P.#79 · 29,015 sh	29,015	$15.6M	0.02%	-14.3%
80	GILDER GAGNON HOWE#80 · 28,573 sh	28,573	$15.3M	0.16%	-2.8%
81	WELLS FARGO & COMPANY#81 · 26,536 sh	26,536	$14.2M	<0.01%	-17.6%
82	SEI INVESTMENTS#82 · 25,826 sh	25,826	$13.9M	0.01%	+6.7%
83	Integral Health Asset Management#83 · 25,000 sh	25,000	$13.4M	0.53%	0.0%
84	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM#84 · 24,277 sh	24,277	$13.0M	<0.01%	+4.7%
85	WCM INVESTMENT MANAGEMENT#85 · 22,985 sh	22,985	$12.1M	0.02%	-2.4%
86	Susquehanna Portfolio Strategies#86 · 22,003 sh	22,003	$11.8M	0.19%	+252.0%
87	Tao Capital Management#87 · 21,000 sh	21,000	$11.3M	0.58%	0.0%
88	HSBC PLC#88 · 20,240 sh	20,240	$10.9M	<0.01%	+1738.3%
89	FIRST ADVISORS#89 · 19,826 sh	19,826	$10.6M	<0.01%	-10.8%
90	Weiss Asset Management#90 · 19,325 sh	19,325	$10.4M	0.11%	New
91	RAYMOND JAMES FINANCIAL#91 · 19,305 sh	19,305	$10.4M	<0.01%	-71.0%
92	ArrowMark Colorado#92 · 18,624 sh	18,624	$10.0M	0.42%	-70.2%
93	RHUMBLINE ADVISERS#93 · 18,154 sh	18,154	$9.7M	<0.01%	-16.6%
94	SPHERA FUNDS MANAGEMENT LTD.#94 · 17,419 sh	17,419	$9.4M	1.22%	+92.7%
95	AQR CAPITAL MANAGEMENT#95 · 15,827 sh	15,827	$8.5M	<0.01%	-0.8%
96	SILVERCREST ASSET MANAGEMENT GROUP#96 · 15,655 sh	15,655	$8.4M	0.06%	-1.9%
97	VANGUARD ASSET MANAGEMENT, Ltd#97 · 15,204 sh	15,204	$8.2M	<0.01%	+7.9%
98	SHIKIAR ASSET MANAGEMENT#98 · 14,950 sh	14,950	$8.0M	—	+273.8%
99	FEDERATED HERMES#99 · 14,914 sh	14,914	$8.0M	0.01%	-11.8%
100	Universal- Beteiligungs- und Servicegesellschaft mbH#100 · 14,263 sh	14,263	$7.7M	0.01%	-22.7%

Funds that sold out of MDGL in Q2 2026 (41)

Held MDGL at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held MDGL in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.185,331 sh	185,331	$97.0M
Logos Global Management85,000 sh	85,000	$44.5M
EMERALD MUTUAL FUND ADVISERS16,500 sh	16,500	$8.6M
Walleye Capital13,227 sh	13,227	$6.9M
Eversept Partners10,000 sh	10,000	$5.2M
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.8,456 sh	8,456	$4.4M
Entropy Technologies5,626 sh	5,626	$2.9M
INTECH INVESTMENT MANAGEMENT4,238 sh	4,238	$2.2M
Bridgewater Associates3,920 sh	3,920	$2.1M
MOODY ALDRICH PARTNERS3,829 sh	3,829	$2.0M
Magnetar Financial3,811 sh	3,811	$2.0M
FARALLON CAPITAL MANAGEMENT3,319 sh	3,319	$1.7M
CI INVESTMENTS2,021 sh	2,021	$1.1M
Ameritas Investment Partners1,400 sh	1,400	$732.9K
PRINCIPAL FINANCIAL GROUP1,239 sh	1,239	$648.6K
FRED ALGER MANAGEMENT1,039 sh	1,039	$543.9K
Havemeyer Place965 sh	965	$505.1K
DARK FOREST CAPITAL MANAGEMENT928 sh	928	$485.8K
CIBC Bancorp USA916 sh	916	$479.5K
AIGEN INVESTMENT MANAGEMENT881 sh	881	$461.2K
Voleon Capital Management822 sh	822	$430.3K
GLENMEDE NA772 sh	772	$404.1K
AlphaGrep UK Ltd758 sh	758	$396.8K
Miracle Mile Advisors703 sh	703	$368.0K
Mariner567 sh	567	$296.2K
McGowan Group Asset Management500 sh	500	$261.7K
Kestra Investment Management460 sh	460	$240.8K
Everhart Financial Group459 sh	459	$240.3K
DRW Securities420 sh	420	$219.9K
Net Worth Advisory Group388 sh	388	$202.9K
Kemnay Advisory Services155 sh	155	$81.1K
MAI Capital Management130 sh	130	$68.1K
Optiver Holding B.V.44 sh	44	$23.0K
Sound Income Strategies26 sh	26	$13.8K
Compagnie Lombard Odier SCmA24 sh	24	$12.6K
MEEDER ASSET MANAGEMENT17 sh	17	$8.9K
TWIN PEAKS WEALTH ADVISORS9 sh	9	$4.7K
WEBSTER BANK, N. A.6 sh	6	$3.1K
NATIONAL BANK OF CANADA6 sh	6	$3.1K
Rachor Investment Advisory Services5 sh	5	$2.6K
Avion Wealth1 sh	1	$0.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.