Maze Therapeutics, Inc. (MAZE) — Institutional Holders, Q2 2026

162 institutional investment managers reported a MAZE position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $1.7B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← MAZE stock profile

MAZE in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

Trimmed

Sold out

Biggest buyers

T. Rowe Price Investment ManagementNew · +2,603,682 sh+$77.7M
BRAIDWELLNew · +1,140,040 sh+$34.0M
BlackRockAdded · +932,416 sh+$27.8M
JPMORGAN CHASEAdded · +905,565 sh+$27.0M
FARALLON CAPITAL MANAGEMENTAdded · +734,814 sh+$21.9M

Biggest sellers

Paradigm Biocapital AdvisorsSold out · -2,744,399 sh-$81.9M
ADAGE CAPITAL PARTNERS GP, L.L.C.Trimmed · -930,000 sh-$27.8M
Cormorant Asset ManagementSold out · -750,000 sh-$22.4M
Caligan PartnersSold out · -614,962 sh-$18.4M
BALYASNY ASSET MANAGEMENT L.P.Trimmed · -440,961 sh-$13.2M

MAZE 13F holders ranked 1–100 of 162

Institutional investors reporting a position in Maze Therapeutics, Inc. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	Frazier Life Sciences Management, L.P.#1 · 5,032,915 sh	5,032,915	$150.2M	3.27%	+10.2%
2	TRV GP IV#2 · 4,473,958 sh	4,473,958	$133.5M	52.63%	0.0%
3	ARCH Venture Management#3 · 4,120,053 sh	4,120,053	$123.0M	11.18%	0.0%
4	Deep Track Capital#4 · 3,732,569 sh	3,732,569	$111.4M	1.62%	+7.3%
5	BlackRock#5 · 3,502,841 sh	3,502,841	$104.5M	<0.01%	+36.3%
6	Jupiter Topco#6 · 3,408,045 sh	3,408,045	$101.8M	0.04%	—
7	T. Rowe Price Investment Management#7 · 2,603,682 sh	2,603,682	$77.7M	0.05%	New
8	Logos Global Management#8 · 1,935,000 sh	1,935,000	$57.7M	2.49%	+56.7%
9	VANGUARD CAPITAL MANAGEMENT#9 · 1,778,222 sh	1,778,222	$53.1M	<0.01%	+23.9%
10	a16z Capital Management, L.L.C.#10 · 1,702,225 sh	1,702,225	$50.8M	0.36%	0.0%
11	VR Adviser#11 · 1,602,034 sh	1,602,034	$47.8M	1.45%	0.0%
12	Alphabet#12 · 1,388,583 sh	1,388,583	$41.4M	0.04%	0.0%
13	BRAIDWELL#13 · 1,140,040 sh	1,140,040	$34.0M	1.26%	New
14	FARALLON CAPITAL MANAGEMENT#14 · 1,107,814 sh	1,107,814	$33.1M	0.15%	+197.0%
15	FMR#15 · 1,056,959 sh	1,056,959	$31.5M	<0.01%	+22.3%
16	General Catalyst Group Management#16 · 1,035,910 sh	1,035,910	$30.9M	16.40%	0.0%
17	STATE STREET#17 · 997,533 sh	997,533	$29.8M	<0.01%	+56.7%
18	DRIEHAUS CAPITAL MANAGEMENT#18 · 954,886 sh	954,886	$28.5M	0.17%	+50.1%
19	TRV GP V#19 · 950,800 sh	950,800	$28.4M	5.69%	0.0%
20	JPMORGAN CHASE#20 · 964,011 sh	964,011	$28.0M	<0.01%	+1549.4%
21	MARSHALL WACE, LLP#21 · 914,572 sh	914,572	$27.3M	0.02%	+194.4%
22	GEODE CAPITAL MANAGEMENT#22 · 858,054 sh	858,054	$25.6M	<0.01%	+43.0%
23	CITADEL ADVISORS#23 · 852,676 sh	852,676	$25.4M	<0.01%	+9.9%
24	Casdin Capital#24 · 843,857 sh	843,857	$25.2M	1.26%	+11.2%
25	ArrowMark Colorado#25 · 767,383 sh	767,383	$22.9M	0.95%	0.0%
26	Woodline Partners#26 · 736,216 sh	736,216	$22.0M	0.07%	+13.2%
27	BESSEMER GROUP#27 · 481,790 sh	481,790	$14.4M	0.02%	0.0%
28	SPHERA FUNDS MANAGEMENT LTD.#28 · 417,564 sh	417,564	$12.5M	1.63%	+83.7%
29	VANGUARD PORTFOLIO MANAGEMENT#29 · 393,107 sh	393,107	$11.7M	<0.01%	+101.0%
30	abrdn plc#30 · 383,773 sh	383,773	$11.5M	0.02%	+69.6%
31	Ikarian Capital#31 · 378,999 sh	378,999	$11.3M	1.22%	0.0%
32	Hillhouse Capital Advisors, Ltd.#32 · 366,028 sh	366,028	$10.9M	1.31%	0.0%
33	ADAR1 Capital Management#33 · 339,276 sh	339,276	$10.1M	0.46%	+577.3%
34	Squadron Capital Management#34 · 335,000 sh	335,000	$10.0M	3.10%	+30.1%
35	BANK OF AMERICA#35 · 321,227 sh	321,227	$9.6M	<0.01%	+64.7%
36	NORTHERN#36 · 294,742 sh	294,742	$8.8M	<0.01%	+39.4%
37	GOLDMAN SACHS GROUP#37 · 293,144 sh	293,144	$8.7M	<0.01%	+4.8%
38	Candriam S.C.A.#38 · 273,932 sh	273,932	$8.2M	0.04%	-1.5%
39	Hudson Bay Capital Management#39 · 270,000 sh	270,000	$8.1M	0.02%	+3212.9%
40	CHARLES SCHWAB INVESTMENT MANAGEMENT#40 · 260,566 sh	260,566	$7.8M	<0.01%	+39.8%
41	ADAGE CAPITAL PARTNERS GP, L.L.C.#41 · 248,000 sh	248,000	$7.4M	0.01%	-78.9%
42	Mass General Brigham#42 · 239,994 sh	239,994	$7.2M	1.98%	0.0%
43	AMERIPRISE FINANCIAL#43 · 227,425 sh	227,425	$6.8M	<0.01%	+111.6%
44	VANGUARD FIDUCIARY#44 · 219,938 sh	219,938	$6.6M	<0.01%	+45.7%
45	RTW INVESTMENTS#45 · 212,000 sh	212,000	$6.3M	0.05%	New
46	SCHRODER INVESTMENT MANAGEMENT GROUP#46 · 199,872 sh	199,872	$5.8M	<0.01%	+437.6%
47	TWO SIGMA INVESTMENTS#47 · 192,952 sh	192,952	$5.8M	<0.01%	+1117.7%
48	BOOTHBAY FUND MANAGEMENT#48 · 188,857 sh	188,857	$5.6M	0.07%	-33.6%
49	ExodusPoint Capital Management#49 · 183,264 sh	183,264	$5.5M	0.04%	New
50	SummitTX Capital, L.P.#50 · 176,291 sh	176,291	$5.3M	0.14%	+110.5%
51	HighVista Strategies#51 · 136,572 sh	136,572	$4.1M	0.93%	+36.8%
52	MORGAN STANLEY#52 · 135,168 sh	135,168	$4.0M	<0.01%	-34.0%
53	PRICE T ROWE ASSOCIATES#53 · 132,870 sh	132,870	$4.0M	<0.01%	+8.3%
54	Qube Research & Technologies Ltd#54 · 131,043 sh	131,043	$3.9M	<0.01%	-2.9%
55	Walleye Capital#55 · 128,006 sh	128,006	$3.8M	0.01%	+358.1%
56	Exome Asset Management#56 · 114,692 sh	114,692	$3.4M	2.11%	+29.6%
57	Ensign Peak Advisors#57 · 101,644 sh	101,644	$3.0M	<0.01%	-45.3%
58	Alyeska Investment Group, L.P.#58 · 100,000 sh	100,000	$3.0M	<0.01%	0.0%
59	Bank of New York Mellon#59 · 97,588 sh	97,588	$2.9M	<0.01%	+31.4%
60	ALGERT GLOBAL#60 · 93,357 sh	93,357	$2.8M	0.03%	New
61	UBS Group AG#61 · 84,679 sh	84,679	$2.5M	<0.01%	-9.8%
62	WELLINGTON MANAGEMENT GROUP LLP#62 · 82,724 sh	82,724	$2.5M	<0.01%	+36.5%
63	Trexquant Investment#63 · 81,668 sh	81,668	$2.4M	0.01%	New
64	FRANKLIN RESOURCES#64 · 80,216 sh	80,216	$2.4M	<0.01%	+34.5%
65	Nuveen#65 · 78,468 sh	78,468	$2.3M	<0.01%	+23.8%
66	OSAIC#66 · 77,850 sh	77,850	$2.3M	<0.01%	+29.9%
67	BNP PARIBAS FINANCIAL MARKETS#67 · 77,251 sh	77,251	$2.3M	<0.01%	+1093.1%
68	XTX Topco Ltd#68 · 75,317 sh	75,317	$2.2M	0.03%	+180.5%
69	LOS ANGELES CAPITAL MANAGEMENT#69 · 74,384 sh	74,384	$2.2M	<0.01%	+689.6%
70	RAYMOND JAMES FINANCIAL#70 · 66,353 sh	66,353	$2.0M	<0.01%	-4.4%
71	JACOBS LEVY EQUITY MANAGEMENT#71 · 65,468 sh	65,468	$2.0M	<0.01%	New
72	DAFNA Capital Management#72 · 65,000 sh	65,000	$1.9M	0.37%	+85.7%
73	ALPS ADVISORS#73 · 55,970 sh	55,970	$1.7M	<0.01%	+42.9%
74	Jump Financial#74 · 47,129 sh	47,129	$1.4M	0.01%	New
75	Swiss National Bank#75 · 47,100 sh	47,100	$1.4M	<0.01%	New
76	FIRST ADVISORS#76 · 46,227 sh	46,227	$1.4M	<0.01%	+81.4%
77	Propel Bio Management#77 · 43,798 sh	43,798	$1.3M	0.68%	0.0%
78	RHUMBLINE ADVISERS#78 · 42,873 sh	42,873	$1.3M	<0.01%	+36.0%
79	ALLIANCEBERNSTEIN L.P.#79 · 37,800 sh	37,800	$1.1M	<0.01%	-41.6%
80	DEUTSCHE BANK AG\#80 · 34,993 sh	34,993	$1.0M	<0.01%	+72.7%
81	WELLS FARGO & COMPANY#81 · 32,047 sh	32,047	$956.3K	<0.01%	+209.1%
82	CITIGROUP#82 · 30,265 sh	30,265	$903.1K	<0.01%	+253.4%
83	Quadrature Capital Ltd#83 · 30,047 sh	30,047	$896.6K	<0.01%	New
84	Invesco Ltd.#84 · 28,372 sh	28,372	$846.6K	<0.01%	-67.2%
85	AQR CAPITAL MANAGEMENT#85 · 27,161 sh	27,161	$810.5K	<0.01%	-2.8%
86	STATE OF WISCONSIN INVESTMENT BOARD#86 · 23,840 sh	23,840	$711.4K	<0.01%	New
87	BARCLAYS PLC#87 · 23,733 sh	23,733	$708.2K	<0.01%	+156.2%
88	SUSQUEHANNA INTERNATIONAL GROUP, LLP#88 · 23,677 sh	23,677	$706.5K	<0.01%	-6.4%
89	TD ASSET MANAGEMENT#89 · 22,174 sh	22,174	$661.7K	<0.01%	New
90	MetLife Investment Management#90 · 20,899 sh	20,899	$623.6K	<0.01%	+43.7%
91	BALYASNY ASSET MANAGEMENT L.P.#91 · 20,190 sh	20,190	$602.5K	<0.01%	-95.6%
92	Squarepoint Ops#92 · 19,434 sh	19,434	$579.9K	<0.01%	+42.8%
93	Verition Fund Management#93 · 18,201 sh	18,201	$543.1K	<0.01%	-4.9%
94	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#94 · 17,739 sh	17,739	$529.3K	<0.01%	+4054.3%
95	Jackson Creek Investment Advisors#95 · 18,345 sh	18,345	$494.0K	0.16%	New
96	VANGUARD ASSET MANAGEMENT, Ltd#96 · 16,436 sh	16,436	$490.4K	<0.01%	New
97	MANUFACTURERS LIFE INSURANCE COMPANY, THE#97 · 16,402 sh	16,402	$489.4K	<0.01%	+12.6%
98	MIRAE ASSET GLOBAL ETFS Ltd.#98 · 16,248 sh	16,248	$484.8K	<0.01%	+30.9%
99	Legal & General Group Plc#99 · 15,781 sh	15,781	$470.9K	<0.01%	+172.6%
100	AXQ CAPITAL#100 · 15,193 sh	15,193	$453.4K	0.05%	+114.1%

Funds that sold out of MAZE in Q2 2026 (39)

Held MAZE at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held MAZE in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
Paradigm Biocapital Advisors2,744,399 sh	2,744,399	$81.9M
Cormorant Asset Management750,000 sh	750,000	$22.4M
Caligan Partners614,962 sh	614,962	$18.4M
WASHINGTON UNIVERSITY280,802 sh	280,802	$8.4M
Freestone Grove Partners234,953 sh	234,953	$7.0M
Spruce Street Capital200,000 sh	200,000	$6.0M
Foresite Capital Management IV156,901 sh	156,901	$4.7M
Holocene Advisors136,168 sh	136,168	$4.1M
Atika Capital Management111,500 sh	111,500	$3.3M
Integral Health Asset Management100,000 sh	100,000	$3.0M
Aquatic Capital Management34,977 sh	34,977	$1.0M
Parkman Healthcare Partners31,844 sh	31,844	$950.5K
TWINBEECH CAPITAL30,989 sh	30,989	$925.0K
Seven Fleet Capital Management30,707 sh	30,707	$916.6K
MILLENNIUM MANAGEMENT29,892 sh	29,892	$892.3K
Foresite Capital Management V25,905 sh	25,905	$773.3K
Blackstone24,990 sh	24,990	$746.0K
ACUTA CAPITAL PARTNERS19,335 sh	19,335	$577.1K
PRELUDE CAPITAL MANAGEMENT18,127 sh	18,127	$541.1K
GILDER GAGNON HOWE17,487 sh	17,487	$522.0K
RENAISSANCE TECHNOLOGIES15,800 sh	15,800	$471.6K
DIADEMA PARTNERS15,000 sh	15,000	$447.8K
Ground Swell Capital13,609 sh	13,609	$406.2K
AMERICAN CENTURY COMPANIES9,635 sh	9,635	$287.6K
CAPSTONE INVESTMENT ADVISORS9,139 sh	9,139	$272.8K
Voleon Capital Management7,287 sh	7,287	$217.5K
MANGROVE PARTNERS IM6,748 sh	6,748	$201.4K
STRS OHIO6,300 sh	6,300	$188.1K
Caption Management5,000 sh	5,000	$149.3K
QUADRANT CAPITAL GROUP8 sh	8	$49.1K
FEDERATED HERMES1,097 sh	1,097	$32.7K
Kemnay Advisory Services306 sh	306	$9.1K
SMA Capital134 sh	134	$4.0K
Larson Financial Group6 sh	6	$179.00
MAI Capital Management5 sh	5	$150.00
True Wealth Design5 sh	5	$150.00
Rachor Investment Advisory Services3 sh	3	$90.00
Stone House Investment Management2 sh	2	$60.00
Hughes Financial Services1 sh	1	$30.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.