IRONWOOD PHARMACEUTICALS INC (IRWD) — Institutional Holders, Q2 2026
212 institutional investment managers reported a IRWD position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $675.8M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
IRWD in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- BlackRockAdded · +4,425,627 sh+$18.6M
- MACKENZIE FINANCIALAdded · +1,807,459 sh+$7.6M
- STATE STREETAdded · +1,352,657 sh+$5.7M
- WELLS FARGO & COMPANYAdded · +1,147,348 sh+$4.8M
- Pacer AdvisorsNew · +1,095,513 sh+$4.6M
Biggest sellers
- CHARLES SCHWAB INVESTMENT MANAGEMENTTrimmed · -1,435,615 sh-$6.0M
- SUSQUEHANNA INTERNATIONAL GROUP, LLPTrimmed · -1,342,920 sh-$5.7M
- TWO SIGMA INVESTMENTSTrimmed · -1,292,187 sh-$5.4M
- Qube Research & Technologies LtdTrimmed · -1,242,096 sh-$5.2M
- VANGUARD PORTFOLIO MANAGEMENTTrimmed · -1,168,682 sh-$4.9M
IRWD 13F holders ranked 1–100 of 212
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | BlackRock#1 · 17,788,557 sh | 17,788,557 | $74.9M | <0.01% | +33.1% |
| 2 | ARMISTICE CAPITAL#2 · 13,932,000 sh | 13,932,000 | $58.7M | 0.72% | -7.3% |
| 3 | Sarissa Capital Management#3 · 9,188,635 sh | 9,188,635 | $38.7M | 21.75% | 0.0% |
| 4 | STATE STREET#4 · 8,809,601 sh | 8,809,601 | $37.1M | <0.01% | +18.1% |
| 5 | BANK OF AMERICA#5 · 8,683,803 sh | 8,683,803 | $36.6M | <0.01% | 0.0% |
| 6 | RENAISSANCE TECHNOLOGIES#6 · 7,993,226 sh | 7,993,226 | $33.7M | 0.05% | -0.8% |
| 7 | VANGUARD CAPITAL MANAGEMENT#7 · 6,608,508 sh | 6,608,508 | $27.8M | <0.01% | +8.4% |
| 8 | AQR CAPITAL MANAGEMENT#8 · 6,465,921 sh | 6,465,921 | $27.2M | <0.01% | -14.2% |
| 9 | ACADIAN ASSET MANAGEMENT#9 · 5,853,331 sh | 5,853,331 | $24.6M | 0.03% | -11.0% |
| 10 | VANGUARD PORTFOLIO MANAGEMENT#10 · 5,513,355 sh | 5,513,355 | $23.2M | <0.01% | -17.5% |
| 11 | GEODE CAPITAL MANAGEMENT#11 · 4,831,657 sh | 4,831,657 | $20.3M | <0.01% | +6.3% |
| 12 | TWO SIGMA INVESTMENTS#12 · 4,556,089 sh | 4,556,089 | $19.2M | 0.01% | -22.1% |
| 13 | MARSHALL WACE, LLP#13 · 4,290,093 sh | 4,290,093 | $18.1M | 0.01% | -5.2% |
| 14 | JACOBS LEVY EQUITY MANAGEMENT#14 · 4,065,964 sh | 4,065,964 | $17.1M | 0.06% | +11.9% |
| 15 | GOLDMAN SACHS GROUP#15 · 3,313,808 sh | 3,313,808 | $14.0M | <0.01% | +23.2% |
| 16 | CHARLES SCHWAB INVESTMENT MANAGEMENT#16 · 3,302,242 sh | 3,302,242 | $13.9M | <0.01% | -30.3% |
| 17 | FEDERATED HERMES#17 · 3,231,238 sh | 3,231,238 | $13.6M | 0.02% | -3.5% |
| 18 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP#18 · 3,017,089 sh | 3,017,089 | $12.7M | <0.01% | -11.2% |
| 19 | DIMENSIONAL FUND ADVISORS#19 · 2,522,891 sh | 2,522,891 | $10.6M | <0.01% | +21.2% |
| 20 | MACKENZIE FINANCIAL#20 · 2,367,493 sh | 2,367,493 | $10.0M | <0.01% | +322.7% |
| 21 | MORGAN STANLEY#21 · 1,859,914 sh | 1,859,914 | $7.8M | <0.01% | +125.5% |
| 22 | Connor, Clark & Lunn Investment Management Ltd.#22 · 1,811,714 sh | 1,811,714 | $7.6M | 0.01% | -1.3% |
| 23 | NORTHERN#23 · 1,373,974 sh | 1,373,974 | $5.8M | <0.01% | +8.5% |
| 24 | Hillsdale Investment Management#24 · 1,250,428 sh | 1,250,428 | $5.3M | 0.12% | +1.1% |
| 25 | WELLS FARGO & COMPANY#25 · 1,206,198 sh | 1,206,198 | $5.1M | <0.01% | +1789.1% |
| 26 | DEUTSCHE BANK AG\#26 · 1,158,138 sh | 1,158,138 | $4.9M | <0.01% | +2.9% |
| 27 | Pacer Advisors#27 · 1,095,513 sh | 1,095,513 | $4.6M | 0.01% | New |
| 28 | VANGUARD FIDUCIARY#28 · 1,040,335 sh | 1,040,335 | $4.4M | <0.01% | +5.2% |
| 29 | FRANKLIN RESOURCES#29 · 1,006,979 sh | 1,006,979 | $4.2M | <0.01% | +35.2% |
| 30 | FMR#30 · 909,488 sh | 909,488 | $3.8M | <0.01% | +15.1% |
| 31 | STATE OF WISCONSIN INVESTMENT BOARD#31 · 778,515 sh | 778,515 | $3.3M | <0.01% | +30.2% |
| 32 | RAYMOND JAMES FINANCIAL#32 · 725,085 sh | 725,085 | $3.1M | <0.01% | -5.1% |
| 33 | VICTORY CAPITAL MANAGEMENT#33 · 658,457 sh | 658,457 | $2.8M | <0.01% | -7.7% |
| 34 | Inspire Investing#34 · 630,072 sh | 630,072 | $2.7M | — | +23.6% |
| 35 | HRT FINANCIAL#35 · 577,337 sh | 577,337 | $2.4M | <0.01% | New |
| 36 | IEQ CAPITAL#36 · 561,588 sh | 561,588 | $2.4M | 0.01% | -24.4% |
| 37 | Vanguard Global Advisers#37 · 561,038 sh | 561,038 | $2.4M | <0.01% | -5.1% |
| 38 | PRUDENTIAL FINANCIAL#38 · 537,199 sh | 537,199 | $2.3M | <0.01% | +19.4% |
| 39 | Bank of New York Mellon#39 · 508,880 sh | 508,880 | $2.1M | <0.01% | +5.1% |
| 40 | CITADEL ADVISORS#40 · 502,403 sh | 502,403 | $2.1M | <0.01% | +324.8% |
| 41 | VOYA INVESTMENT MANAGEMENT#41 · 484,450 sh | 484,450 | $2.0M | <0.01% | +232.2% |
| 42 | WELLINGTON MANAGEMENT GROUP LLP#42 · 468,821 sh | 468,821 | $2.0M | <0.01% | +3.4% |
| 43 | SEI INVESTMENTS#43 · 459,417 sh | 459,417 | $1.9M | <0.01% | -38.1% |
| 44 | O'SHAUGHNESSY ASSET MANAGEMENT#44 · 438,911 sh | 438,911 | $1.8M | <0.01% | +242.2% |
| 45 | WEDGE CAPITAL MANAGEMENT L L P#45 · 435,650 sh | 435,650 | $1.8M | — | -19.4% |
| 46 | SEGALL BRYANT & HAMILL#46 · 408,064 sh | 408,064 | $1.7M | 0.02% | New |
| 47 | Invesco Ltd.#47 · 403,209 sh | 403,209 | $1.7M | <0.01% | -26.3% |
| 48 | Man Group plc#48 · 392,117 sh | 392,117 | $1.7M | <0.01% | -27.5% |
| 49 | BRIDGEWAY CAPITAL MANAGEMENT#49 · 389,793 sh | 389,793 | $1.6M | 0.03% | -11.5% |
| 50 | UBS Group AG#50 · 389,529 sh | 389,529 | $1.6M | <0.01% | -88.9% |
| 51 | BNP Paribas Asset Management Holding S.A.#51 · 375,288 sh | 375,288 | $1.6M | <0.01% | 0.0% |
| 52 | RITHOLTZ WEALTH MANAGEMENT#52 · 360,094 sh | 360,094 | $1.5M | 0.02% | +311.4% |
| 53 | Nuveen#53 · 355,372 sh | 355,372 | $1.5M | <0.01% | +52.3% |
| 54 | CM Management#54 · 350,000 sh | 350,000 | $1.5M | 0.94% | 0.0% |
| 55 | Qube Research & Technologies Ltd#55 · 347,985 sh | 347,985 | $1.5M | <0.01% | -78.1% |
| 56 | Robeco Institutional Asset Management B.V.#56 · 342,998 sh | 342,998 | $1.4M | — | 0.0% |
| 57 | LOS ANGELES CAPITAL MANAGEMENT#57 · 342,293 sh | 342,293 | $1.4M | <0.01% | -32.8% |
| 58 | Virtus Investment Advisers#58 · 318,598 sh | 318,598 | $1.3M | 0.31% | +318.3% |
| 59 | LSV ASSET MANAGEMENT#59 · 308,271 sh | 308,271 | $1.3M | <0.01% | 0.0% |
| 60 | CWA Asset Management Group#60 · 290,366 sh | 290,366 | $1.2M | — | New |
| 61 | GLOBEFLEX CAPITAL L P#61 · 259,809 sh | 259,809 | $1.1M | 0.14% | 0.0% |
| 62 | GSA CAPITAL PARTNERS LLP#62 · 259,512 sh | 259,512 | $1.1M | 0.07% | -60.3% |
| 63 | CITIGROUP#63 · 226,824 sh | 226,824 | $954.9K | <0.01% | +475.6% |
| 64 | Russell Investments Group, Ltd.#64 · 224,821 sh | 224,821 | $946.5K | <0.01% | -14.1% |
| 65 | JPMORGAN CHASE#65 · 212,575 sh | 212,575 | $914.1K | <0.01% | -49.3% |
| 66 | WEALTH ENHANCEMENT ADVISORY SERVICES#66 · 219,445 sh | 219,445 | $913.3K | — | -3.2% |
| 67 | Cerity Partners#67 · 208,019 sh | 208,019 | $875.8K | <0.01% | -43.5% |
| 68 | RHUMBLINE ADVISERS#68 · 205,095 sh | 205,095 | $863.4K | <0.01% | +6.3% |
| 69 | MARTINGALE ASSET MANAGEMENT L P#69 · 204,991 sh | 204,991 | $863.0K | 0.02% | 0.0% |
| 70 | EVOLVE PRIVATE WEALTH#70 · 186,864 sh | 186,864 | $786.7K | 0.05% | +1108.1% |
| 71 | Vident Advisory#71 · 180,929 sh | 180,929 | $761.7K | <0.01% | -1.8% |
| 72 | Creative Planning#72 · 177,030 sh | 177,030 | $745.3K | <0.01% | -0.3% |
| 73 | KLP KAPITALFORVALTNING AS#73 · 174,200 sh | 174,200 | $733.4K | <0.01% | 0.0% |
| 74 | Mariner#74 · 168,472 sh | 168,472 | $709.3K | <0.01% | -18.9% |
| 75 | OMERS ADMINISTRATION#75 · 159,010 sh | 159,010 | $669.4K | <0.01% | -29.7% |
| 76 | Rafferty Asset Management#76 · 152,878 sh | 152,878 | $643.6K | <0.01% | -29.4% |
| 77 | Quantinno Capital Management#77 · 150,604 sh | 150,604 | $634.0K | <0.01% | +16.1% |
| 78 | ALLIANCEBERNSTEIN L.P.#78 · 165,790 sh | 165,790 | $581.9K | <0.01% | 0.0% |
| 79 | FIFTH THIRD BANCORP#79 · 132,748 sh | 132,748 | $558.9K | <0.01% | -19.6% |
| 80 | CANADA PENSION PLAN INVESTMENT BOARD#80 · 130,900 sh | 130,900 | $551.1K | <0.01% | -3.0% |
| 81 | JANE STREET GROUP#81 · 129,700 sh | 129,700 | $546.0K | 0.00% | -79.2% |
| 82 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#82 · 129,237 sh | 129,237 | $544.1K | 0.00% | -91.2% |
| 83 | SG Americas Securities#83 · 129,280 sh | 129,280 | $544.0K | <0.01% | +13.8% |
| 84 | PRICE T ROWE ASSOCIATES#84 · 128,772 sh | 128,772 | $543.0K | <0.01% | +3.6% |
| 85 | HSBC PLC#85 · 126,100 sh | 126,100 | $541.6K | <0.01% | +324.5% |
| 86 | SRS Capital Advisors#86 · 126,966 sh | 126,966 | $534.5K | <0.01% | +7355.4% |
| 87 | MERCER GLOBAL ADVISORS#87 · 126,160 sh | 126,160 | $531.1K | <0.01% | +9.6% |
| 88 | D. E. Shaw#88 · 122,907 sh | 122,907 | $517.4K | <0.01% | -99.6% |
| 89 | Optimist Retirement Group#89 · 102,054 sh | 102,054 | $429.6K | 0.17% | +7.6% |
| 90 | State of Wyoming#90 · 101,781 sh | 101,781 | $428.5K | 0.04% | -20.6% |
| 91 | Cercano Management#91 · 101,378 sh | 101,378 | $426.8K | 0.04% | 0.0% |
| 92 | BARCLAYS PLC#92 · 100,123 sh | 100,123 | $421.5K | <0.01% | +11.3% |
| 93 | AMERIPRISE FINANCIAL#93 · 99,526 sh | 99,526 | $419.0K | <0.01% | +0.2% |
| 94 | Engineers Gate Manager#94 · 98,052 sh | 98,052 | $412.8K | <0.01% | +22.8% |
| 95 | MetLife Investment Management#95 · 96,208 sh | 96,208 | $405.0K | <0.01% | +50.9% |
| 96 | Integrated Quantitative Investments#96 · 93,689 sh | 93,689 | $394.4K | 0.06% | -83.0% |
| 97 | MIRAE ASSET GLOBAL ETFS Ltd.#97 · 93,191 sh | 93,191 | $393.9K | <0.01% | +3.4% |
| 98 | FULLER & THALER ASSET MANAGEMENT#98 · 90,321 sh | 90,321 | $380.3K | <0.01% | -0.8% |
| 99 | WINTON GROUP Ltd#99 · 84,156 sh | 84,156 | $354.3K | 0.01% | -65.2% |
| 100 | Allspring Global Investments#100 · 82,315 sh | 82,315 | $339.1K | <0.01% | +3.9% |
Funds that sold out of IRWD in Q2 2026 (36)
Held IRWD at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| MILLENNIUM MANAGEMENT457,114 sh | 457,114 | $1.6M |
| Toroso Investments304,475 sh | 304,475 | $1.1M |
| Harvest Investment Services241,881 sh | 241,881 | $849.0K |
| Hennion & Walsh Asset Management184,485 sh | 184,485 | $647.5K |
| Legato Capital Management156,059 sh | 156,059 | $547.8K |
| STRS OHIO97,400 sh | 97,400 | $341.9K |
| EntryPoint Capital86,874 sh | 86,874 | $304.9K |
| CIBC WORLD MARKET71,330 sh | 71,330 | $250.4K |
| BANK OF MONTREAL62,750 sh | 62,750 | $220.3K |
| WEDBUSH SECURITIES60,703 sh | 60,703 | $213.0K |
| VIRTUS ADVISERS58,000 sh | 58,000 | $203.6K |
| Universal- Beteiligungs- und Servicegesellschaft mbH56,132 sh | 56,132 | $197.0K |
| SCOTIA CAPITAL55,272 sh | 55,272 | $194.0K |
| nVerses Capital32,554 sh | 32,554 | $114.3K |
| Graham Capital Management, L.P.30,821 sh | 30,821 | $108.2K |
| OVERSEA-CHINESE BANKING Ltd21,465 sh | 21,465 | $75.3K |
| SIMPLEX TRADING17,724 sh | 17,724 | $62.2K |
| Abacus Wealth Partners17,531 sh | 17,531 | $61.5K |
| Virtu Financial16,960 sh | 16,960 | $60.0K |
| Scientech Research15,917 sh | 15,917 | $55.9K |
| Brevan Howard Capital Management14,218 sh | 14,218 | $49.9K |
| NINE MASTS CAPITAL Ltd13,527 sh | 13,527 | $47.5K |
| Y-Intercept (Hong Kong) Ltd13,470 sh | 13,470 | $47.3K |
| FARALLON CAPITAL MANAGEMENT13,000 sh | 13,000 | $45.6K |
| EVOKE WEALTH12,062 sh | 12,062 | $42.3K |
| waypoint wealth counsel11,999 sh | 11,999 | $42.1K |
| WADDELL & ASSOCIATES11,682 sh | 11,682 | $41.0K |
| MQS Management11,451 sh | 11,451 | $40.2K |
| Simplify Asset Management11,447 sh | 11,447 | $40.2K |
| Gotham Asset Management10,657 sh | 10,657 | $37.4K |
| Financial Management Professionals6,508 sh | 6,508 | $22.8K |
| Carolina Wealth Advisors1,492 sh | 1,492 | $5.2K |
| Intentional Wealth Strategies349 sh | 349 | $1.2K |
| Advisory Services Network235 sh | 235 | $825.00 |
| Root Financial Partners133 sh | 133 | $467.00 |
| Frazier Financial Advisors97 sh | 97 | $341.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.