Disc Medicine, Inc. (IRON) — Institutional Holders, Q2 2026

218 institutional investment managers reported a IRON position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $3.1B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← IRON stock profile

IRON in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

Trimmed

Sold out

Biggest buyers

Vestal Point CapitalAdded · +850,000 sh+$62.2M
JPMORGAN CHASEAdded · +504,315 sh+$36.9M
Opaleye ManagementAdded · +434,000 sh+$31.7M
PRICE T ROWE ASSOCIATESAdded · +326,049 sh+$23.8M
Logos Global ManagementAdded · +315,000 sh+$23.0M

Biggest sellers

ORBIMED ADVISORSTrimmed · -710,015 sh-$51.9M
FMRTrimmed · -692,421 sh-$50.6M
GOLDMAN SACHS GROUPTrimmed · -542,459 sh-$39.7M
JENNISON ASSOCIATESTrimmed · -170,862 sh-$12.5M
Integral Health Asset ManagementSold out · -170,000 sh-$12.4M

IRON 13F holders ranked 1–100 of 218

Institutional investors reporting a position in Disc Medicine, Inc. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	FMR#1 · 4,894,473 sh	4,894,473	$358.0M	0.02%	-12.4%
2	BlackRock#2 · 2,467,899 sh	2,467,899	$180.5M	<0.01%	+8.5%
3	RA CAPITAL MANAGEMENT, L.P.#3 · 2,450,221 sh	2,450,221	$179.2M	1.56%	0.0%
4	JPMORGAN CHASE#4 · 1,875,795 sh	1,875,795	$139.9M	<0.01%	+36.8%
5	PRICE T ROWE ASSOCIATES#5 · 1,875,399 sh	1,875,399	$137.2M	0.01%	+21.0%
6	WELLINGTON MANAGEMENT GROUP LLP#6 · 1,741,351 sh	1,741,351	$127.4M	0.02%	+0.3%
7	STATE STREET#7 · 1,648,836 sh	1,648,836	$120.6M	<0.01%	-2.9%
8	Vestal Point Capital#8 · 1,550,000 sh	1,550,000	$113.4M	2.65%	+121.4%
9	Atlas Venture Life Science Advisors#9 · 1,513,875 sh	1,513,875	$110.7M	12.56%	0.0%
10	VANGUARD CAPITAL MANAGEMENT#10 · 1,369,027 sh	1,369,027	$100.1M	<0.01%	-0.5%
11	Frazier Life Sciences Management, L.P.#11 · 1,354,852 sh	1,354,852	$99.1M	2.16%	0.0%
12	TCG Crossover Management#12 · 1,341,862 sh	1,341,862	$98.1M	2.36%	0.0%
13	BVF#13 · 1,153,612 sh	1,153,612	$84.4M	2.16%	-9.3%
14	Woodline Partners#14 · 958,281 sh	958,281	$70.1M	0.22%	0.0%
15	Siren, L.L.C.#15 · 888,401 sh	888,401	$65.0M	1.31%	-10.1%
16	Logos Global Management#16 · 875,000 sh	875,000	$64.0M	2.75%	+56.2%
17	Opaleye Management#17 · 855,000 sh	855,000	$62.5M	5.66%	+103.1%
18	GEODE CAPITAL MANAGEMENT#18 · 789,724 sh	789,724	$57.8M	<0.01%	+6.1%
19	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)#19 · 657,000 sh	657,000	$48.1M	0.50%	0.0%
20	DIMENSIONAL FUND ADVISORS#20 · 569,018 sh	569,018	$41.6M	<0.01%	+44.3%
21	Bellevue Group AG#21 · 560,000 sh	560,000	$41.0M	0.86%	+21.9%
22	Saturn V Capital Management#22 · 524,730 sh	524,730	$38.4M	5.50%	+16.6%
23	ARMISTICE CAPITAL#23 · 460,000 sh	460,000	$33.6M	0.41%	-14.2%
24	JENNISON ASSOCIATES#24 · 439,520 sh	439,520	$32.1M	0.02%	-28.0%
25	abrdn plc#25 · 438,174 sh	438,174	$32.0M	0.04%	+16.7%
26	Palo Alto Investors#26 · 416,646 sh	416,646	$30.5M	4.21%	+3.7%
27	EVENTIDE ASSET MANAGEMENT#27 · 395,651 sh	395,651	$28.9M	0.39%	0.0%
28	Pictet Asset Management Holding SA#28 · 385,375 sh	385,375	$28.2M	0.03%	-0.4%
29	Assenagon Asset Management S.A.#29 · 384,158 sh	384,158	$28.1M	—	-29.7%
30	LOOMIS SAYLES & L P#30 · 381,864 sh	381,864	$27.9M	0.04%	+20.4%
31	Foresite Capital Management V#31 · 374,069 sh	374,069	$27.4M	7.55%	0.0%
32	ORBIMED ADVISORS#32 · 357,535 sh	357,535	$26.2M	0.48%	-66.5%
33	BAKER BROS. ADVISORS#33 · 349,657 sh	349,657	$25.6M	0.13%	0.0%
34	VANGUARD PORTFOLIO MANAGEMENT#34 · 281,937 sh	281,937	$20.6M	<0.01%	+14.0%
35	Octagon Capital Advisors#35 · 270,000 sh	270,000	$19.7M	1.77%	0.0%
36	NORTHERN#36 · 264,990 sh	264,990	$19.4M	<0.01%	+7.2%
37	CHARLES SCHWAB INVESTMENT MANAGEMENT#37 · 257,382 sh	257,382	$18.8M	<0.01%	+2.5%
38	Checkpoint Capital L.P.#38 · 240,125 sh	240,125	$17.6M	4.51%	-16.2%
39	VANGUARD FIDUCIARY#39 · 225,198 sh	225,198	$16.5M	<0.01%	+3.6%
40	CITADEL ADVISORS#40 · 209,308 sh	209,308	$15.3M	<0.01%	+113.7%
41	Bank of New York Mellon#41 · 204,727 sh	204,727	$15.0M	<0.01%	-0.1%
42	BNP PARIBAS FINANCIAL MARKETS#42 · 184,695 sh	184,695	$13.5M	<0.01%	+44.6%
43	Catalio Capital Management#43 · 159,384 sh	159,384	$11.7M	2.19%	+29.6%
44	Sofinnova Ventures#44 · 146,239 sh	146,239	$10.7M	0.55%	+86.7%
45	Bain Capital Life Sciences Investors#45 · 141,234 sh	141,234	$10.3M	0.61%	0.0%
46	TWO SIGMA INVESTMENTS#46 · 136,750 sh	136,750	$10.0M	<0.01%	New
47	BANK OF AMERICA#47 · 135,111 sh	135,111	$9.9M	<0.01%	-19.0%
48	Alyeska Investment Group, L.P.#48 · 125,000 sh	125,000	$9.1M	0.02%	0.0%
49	Ensign Peak Advisors#49 · 122,111 sh	122,111	$8.9M	0.01%	-36.2%
50	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#50 · 114,109 sh	114,109	$8.3M	<0.01%	+2.9%
51	UBS Group AG#51 · 110,971 sh	110,971	$8.1M	<0.01%	+12.5%
52	Trexquant Investment#52 · 107,699 sh	107,699	$7.9M	0.05%	New
53	KENNEDY CAPITAL MANAGEMENT#53 · 106,769 sh	106,769	$7.8M	0.14%	-1.4%
54	MILLENNIUM MANAGEMENT#54 · 106,248 sh	106,248	$7.8M	<0.01%	+27.6%
55	GOLDMAN SACHS GROUP#55 · 97,383 sh	97,383	$7.1M	<0.01%	-84.8%
56	MORGAN STANLEY#56 · 91,595 sh	91,595	$6.7M	<0.01%	-2.8%
57	HRT FINANCIAL#57 · 90,822 sh	90,822	$6.6M	0.02%	New
58	SILVERARC CAPITAL MANAGEMENT#58 · 82,800 sh	82,800	$6.1M	0.63%	-57.8%
59	RAYMOND JAMES FINANCIAL#59 · 77,980 sh	77,980	$5.7M	<0.01%	+74.5%
60	Squarepoint Ops#60 · 75,872 sh	75,872	$5.5M	<0.01%	+139.3%
61	DnB Asset Management AS#61 · 73,127 sh	73,127	$5.3M	0.01%	-24.4%
62	iA Global Asset Management#62 · 66,023 sh	66,023	$4.8M	0.06%	-0.3%
63	Casdin Capital#63 · 65,000 sh	65,000	$4.8M	0.24%	0.0%
64	SPHERA FUNDS MANAGEMENT LTD.#64 · 63,538 sh	63,538	$4.6M	0.61%	+18.7%
65	Nuveen#65 · 60,357 sh	60,357	$4.4M	<0.01%	+17.5%
66	KVP Capital Advisors#66 · 58,250 sh	58,250	$4.3M	3.13%	0.0%
67	MOORE CAPITAL MANAGEMENT#67 · 57,796 sh	57,796	$4.2M	0.06%	0.0%
68	XTX Topco Ltd#68 · 56,710 sh	56,710	$4.1M	0.05%	+64.8%
69	NEXTBio Capital Management#69 · 52,655 sh	52,655	$3.9M	1.77%	0.0%
70	ALGERT GLOBAL#70 · 51,850 sh	51,850	$3.8M	0.04%	+128.6%
71	ExodusPoint Capital Management#71 · 51,623 sh	51,623	$3.8M	0.02%	New
72	SCHRODER INVESTMENT MANAGEMENT GROUP#72 · 50,000 sh	50,000	$3.7M	<0.01%	-1.9%
73	Burkehill Global Management#73 · 50,000 sh	50,000	$3.7M	0.13%	0.0%
74	Brevan Howard Capital Management#74 · 49,996 sh	49,996	$3.7M	0.03%	+54.3%
75	Swiss National Bank#75 · 49,800 sh	49,800	$3.6M	<0.01%	+3.8%
76	AMERIPRISE FINANCIAL#76 · 45,874 sh	45,874	$3.4M	<0.01%	+0.1%
77	HealthInvest Partners AB#77 · 43,682 sh	43,682	$3.2M	0.86%	-59.3%
78	Quadrature Capital Ltd#78 · 42,419 sh	42,419	$3.1M	0.03%	New
79	Invesco Ltd.#79 · 42,057 sh	42,057	$3.1M	<0.01%	+37.3%
80	ALPS ADVISORS#80 · 38,565 sh	38,565	$2.8M	0.01%	+24.2%
81	CITIGROUP#81 · 38,317 sh	38,317	$2.8M	<0.01%	+394.9%
82	BNP Paribas Asset Management Holding S.A.#82 · 38,262 sh	38,262	$2.8M	<0.01%	-4.1%
83	Universal- Beteiligungs- und Servicegesellschaft mbH#83 · 36,634 sh	36,634	$2.7M	<0.01%	-3.6%
84	RHUMBLINE ADVISERS#84 · 35,844 sh	35,844	$2.6M	<0.01%	+8.4%
85	LAZARD ASSET MANAGEMENT#85 · 35,034 sh	35,034	$2.6M	<0.01%	-11.1%
86	SEVEN GRAND MANAGERS#86 · 35,000 sh	35,000	$2.6M	0.10%	0.0%
87	MARSHALL WACE, LLP#87 · 34,394 sh	34,394	$2.5M	<0.01%	New
88	Jump Financial#88 · 32,549 sh	32,549	$2.4M	0.02%	-60.2%
89	BANK OF MONTREAL#89 · 32,308 sh	32,308	$2.4M	<0.01%	+12.3%
90	DEUTSCHE BANK AG\#90 · 30,643 sh	30,643	$2.2M	<0.01%	+25.6%
91	ALLIANCEBERNSTEIN L.P.#91 · 34,670 sh	34,670	$2.2M	<0.01%	+41.3%
92	RTW INVESTMENTS#92 · 30,000 sh	30,000	$2.2M	0.02%	0.0%
93	VICTORY CAPITAL MANAGEMENT#93 · 29,117 sh	29,117	$2.1M	<0.01%	-0.3%
94	WELLS FARGO & COMPANY#94 · 28,924 sh	28,924	$2.1M	<0.01%	+96.9%
95	TUDOR INVESTMENT ET AL#95 · 28,663 sh	28,663	$2.1M	<0.01%	-7.5%
96	MANUFACTURERS LIFE INSURANCE COMPANY, THE#96 · 27,771 sh	27,771	$2.0M	<0.01%	-14.5%
97	Y-Intercept (Hong Kong) Ltd#97 · 26,888 sh	26,888	$2.0M	—	New
98	Rafferty Asset Management#98 · 26,566 sh	26,566	$1.9M	<0.01%	-50.7%
99	Campbell & Investment Adviser#99 · 25,568 sh	25,568	$1.9M	0.10%	New
100	PNC FINANCIAL SERVICES GROUP#100 · 22,333 sh	22,333	$1.6M	<0.01%	-11.7%

Funds that sold out of IRON in Q2 2026 (23)

Held IRON at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held IRON in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
Integral Health Asset Management170,000 sh	170,000	$10.9M
Freestone Grove Partners68,687 sh	68,687	$4.4M
Sio Capital Management65,203 sh	65,203	$4.2M
RENAISSANCE TECHNOLOGIES31,820 sh	31,820	$2.0M
Nantahala Capital Management25,653 sh	25,653	$1.6M
BOOTHBAY FUND MANAGEMENT21,378 sh	21,378	$1.4M
Zimmer Partners16,700 sh	16,700	$1.1M
Headlands Technologies14,611 sh	14,611	$934.2K
Atom Investors12,162 sh	12,162	$777.6K
Ghisallo Capital Management10,000 sh	10,000	$639.4K
INCEPTIONR6,489 sh	6,489	$414.9K
Seven Fleet Capital Management3,231 sh	3,231	$206.6K
Caitong International Asset Management , Ltd1,001 sh	1,001	$64.0K
Aquatic Capital Management693 sh	693	$44.3K
ANTIPODES PARTNERS Ltd476 sh	476	$30.4K
SUMMIT SECURITIES GROUP287 sh	287	$18.4K
Aster Capital Management (DIFC) Ltd52 sh	52	$2.6K
GROUP ONE TRADING, L.P.11 sh	11	$703.00
CAPITAL & PLANNING6 sh	6	$384.00
Root Financial Partners4 sh	4	$256.00
MAI Capital Management3 sh	3	$192.00
True Wealth Design1 sh	1	$64.00
TWIN PEAKS WEALTH ADVISORS1 sh	1	$64.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.