Opus Genetics, Inc. (IRD) — Institutional Holders, Q2 2026
103 institutional investment managers reported a IRD position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $236.4M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
IRD in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- BlackRockAdded · +2,968,747 sh+$12.2M
- Trails Edge Capital PartnersAdded · +2,243,658 sh+$9.2M
- GREAT POINT PARTNERSAdded · +1,645,847 sh+$6.8M
- Nantahala Capital ManagementAdded · +1,380,029 sh+$5.7M
- GOLDMAN SACHS GROUPAdded · +1,200,420 sh+$4.9M
Biggest sellers
- PERCEPTIVE ADVISORSSold out · -1,835,842 sh-$7.5M
- FARALLON CAPITAL MANAGEMENTSold out · -1,000,000 sh-$4.1M
- SUSQUEHANNA INTERNATIONAL GROUP, LLPTrimmed · -626,486 sh-$2.6M
- Mink Brook Asset ManagementTrimmed · -429,347 sh-$1.8M
- AMERIPRISE FINANCIALSold out · -388,491 sh-$1.6M
IRD 13F holders ranked 1–100 of 103
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | Caligan Partners#1 · 6,077,084 sh | 6,077,084 | $25.0M | 1.18% | 0.0% |
| 2 | ADAGE CAPITAL PARTNERS GP, L.L.C.#2 · 6,029,775 sh | 6,029,775 | $24.8M | 0.03% | 0.0% |
| 3 | BIOS Capital Management#3 · 3,683,429 sh | 3,683,429 | $15.1M | 36.33% | 0.0% |
| 4 | BlackRock#4 · 3,116,487 sh | 3,116,487 | $12.8M | <0.01% | +2009.4% |
| 5 | BALYASNY ASSET MANAGEMENT L.P.#5 · 3,087,866 sh | 3,087,866 | $12.7M | 0.02% | +13.6% |
| 6 | Nantahala Capital Management#6 · 3,061,359 sh | 3,061,359 | $12.6M | 0.42% | +82.1% |
| 7 | VANGUARD CAPITAL MANAGEMENT#7 · 2,958,683 sh | 2,958,683 | $12.2M | <0.01% | +20.8% |
| 8 | Boxer Capital Management#8 · 2,815,000 sh | 2,815,000 | $11.6M | 0.87% | +25.1% |
| 9 | Trails Edge Capital Partners#9 · 2,743,658 sh | 2,743,658 | $11.3M | 1.79% | +448.7% |
| 10 | MILLENNIUM MANAGEMENT#10 · 2,302,101 sh | 2,302,101 | $9.5M | <0.01% | -12.5% |
| 11 | GREAT POINT PARTNERS#11 · 1,970,187 sh | 1,970,187 | $8.1M | 1.53% | +507.4% |
| 12 | MARSHALL WACE, LLP#12 · 1,945,609 sh | 1,945,609 | $8.0M | <0.01% | -15.9% |
| 13 | ADAR1 Capital Management#13 · 1,783,781 sh | 1,783,781 | $7.3M | 0.34% | -3.5% |
| 14 | GOLDMAN SACHS GROUP#14 · 1,527,229 sh | 1,527,229 | $6.3M | <0.01% | +367.3% |
| 15 | Woodline Partners#15 · 1,434,713 sh | 1,434,713 | $5.9M | 0.02% | +6.0% |
| 16 | GEODE CAPITAL MANAGEMENT#16 · 1,367,712 sh | 1,367,712 | $5.6M | <0.01% | +154.1% |
| 17 | BOOTHBAY FUND MANAGEMENT#17 · 1,189,515 sh | 1,189,515 | $4.9M | 0.06% | 0.0% |
| 18 | Opaleye Management#18 · 1,125,000 sh | 1,125,000 | $4.6M | 0.42% | +0.4% |
| 19 | SummitTX Capital, L.P.#19 · 1,007,351 sh | 1,007,351 | $4.1M | 0.11% | New |
| 20 | STATE STREET#20 · 790,136 sh | 790,136 | $3.2M | <0.01% | +295.2% |
| 21 | Bleichroeder#21 · 736,842 sh | 736,842 | $3.0M | 0.54% | 0.0% |
| 22 | UBS Group AG#22 · 683,895 sh | 683,895 | $2.8M | <0.01% | +165.4% |
| 23 | CITADEL ADVISORS#23 · 665,662 sh | 665,662 | $2.7M | <0.01% | +450.6% |
| 24 | MORGAN STANLEY#24 · 464,900 sh | 464,900 | $1.9M | <0.01% | +1076.3% |
| 25 | NORTHERN#25 · 442,154 sh | 442,154 | $1.8M | <0.01% | +368.3% |
| 26 | VANGUARD FIDUCIARY#26 · 410,375 sh | 410,375 | $1.7M | <0.01% | +45.6% |
| 27 | VANGUARD PORTFOLIO MANAGEMENT#27 · 371,950 sh | 371,950 | $1.5M | <0.01% | New |
| 28 | Squarepoint Ops#28 · 330,783 sh | 330,783 | $1.4M | <0.01% | New |
| 29 | TWO SIGMA INVESTMENTS#29 · 253,962 sh | 253,962 | $1.0M | <0.01% | +133.8% |
| 30 | AWM Investment Company#30 · 232,590 sh | 232,590 | $955.9K | 0.08% | New |
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#31 · 196,897 sh | 196,897 | $809.2K | <0.01% | -76.1% |
| 32 | JANE STREET GROUP#32 · 188,988 sh | 188,988 | $776.7K | <0.01% | +19.5% |
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT#33 · 165,053 sh | 165,053 | $678.4K | <0.01% | +371.6% |
| 34 | Mink Brook Asset Management#34 · 161,205 sh | 161,205 | $662.6K | 0.29% | -72.7% |
| 35 | XTX Topco Ltd#35 · 144,095 sh | 144,095 | $592.2K | <0.01% | +762.6% |
| 36 | Seven Fleet Capital Management#36 · 143,137 sh | 143,137 | $588.3K | 0.10% | +6.6% |
| 37 | Creative Planning#37 · 128,366 sh | 128,366 | $527.6K | <0.01% | 0.0% |
| 38 | Texas Capital Bank Wealth Management Services#38 · 122,529 sh | 122,529 | $503.6K | 0.03% | +38.5% |
| 39 | Bank of New York Mellon#39 · 122,479 sh | 122,479 | $503.4K | <0.01% | New |
| 40 | Stonepine Capital Management#40 · 100,718 sh | 100,718 | $414.0K | 0.19% | +46.6% |
| 41 | Jump Financial#41 · 94,820 sh | 94,820 | $389.7K | <0.01% | New |
| 42 | Nuveen#42 · 71,343 sh | 71,343 | $293.2K | <0.01% | New |
| 43 | Palogic Value Management, L.P.#43 · 65,088 sh | 65,088 | $267.5K | 0.09% | +0.1% |
| 44 | Aureus Asset Management#44 · 58,200 sh | 58,200 | $239.2K | 0.01% | New |
| 45 | Regency Capital Management \DE#45 · 58,000 sh | 58,000 | $238.4K | 0.09% | -14.7% |
| 46 | BANK OF AMERICA#46 · 55,005 sh | 55,005 | $226.1K | 0.00% | -17.9% |
| 47 | DEUTSCHE BANK AG\#47 · 53,312 sh | 53,312 | $219.1K | <0.01% | New |
| 48 | Invesco Ltd.#48 · 53,231 sh | 53,231 | $218.8K | 0.00% | New |
| 49 | WELLS FARGO & COMPANY#49 · 52,633 sh | 52,633 | $216.3K | 0.00% | +1290.6% |
| 50 | RHUMBLINE ADVISERS#50 · 51,464 sh | 51,464 | $211.5K | <0.01% | New |
| 51 | EntryPoint Capital#51 · 50,883 sh | 50,883 | $209.1K | 0.05% | New |
| 52 | Quadrature Capital Ltd#52 · 46,389 sh | 46,389 | $190.7K | <0.01% | New |
| 53 | PRICE T ROWE ASSOCIATES#53 · 43,937 sh | 43,937 | $181.0K | 0.00% | New |
| 54 | BRIDGEWAY CAPITAL MANAGEMENT#54 · 42,065 sh | 42,065 | $172.9K | <0.01% | 0.0% |
| 55 | Empowered Funds#55 · 42,065 sh | 42,065 | $172.9K | <0.01% | 0.0% |
| 56 | MANGROVE PARTNERS IM#56 · 41,717 sh | 41,717 | $171.5K | 0.01% | 0.0% |
| 57 | MetLife Investment Management#57 · 32,208 sh | 32,208 | $132.4K | <0.01% | New |
| 58 | CAPTRUST FINANCIAL ADVISORS#58 · 32,000 sh | 32,000 | $131.5K | <0.01% | 0.0% |
| 59 | CITIGROUP#59 · 30,092 sh | 30,092 | $123.7K | 0.00% | New |
| 60 | ALLIANCEBERNSTEIN L.P.#60 · 25,380 sh | 25,380 | $115.5K | 0.00% | New |
| 61 | Miller Financial Services#61 · 27,000 sh | 27,000 | $111.0K | — | +22.7% |
| 62 | SIMPLEX TRADING#62 · 25,553 sh | 25,553 | $105.0K | <0.01% | -69.0% |
| 63 | MIRAE ASSET GLOBAL ETFS Ltd.#63 · 24,657 sh | 24,657 | $101.3K | <0.01% | New |
| 64 | JPMORGAN CHASE#64 · 22,199 sh | 22,199 | $90.1K | 0.00% | New |
| 65 | Point72 Asset Management, L.P.#65 · 18,922 sh | 18,922 | $77.8K | <0.01% | New |
| 66 | NewEdge Advisors#66 · 16,364 sh | 16,364 | $67.3K | <0.01% | 0.0% |
| 67 | JAMES INVESTMENT RESEARCH#67 · 16,364 sh | 16,364 | $67.3K | — | 0.0% |
| 68 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#68 · 15,949 sh | 15,949 | $65.5K | <0.01% | New |
| 69 | State of Wyoming#69 · 15,904 sh | 15,904 | $65.4K | <0.01% | New |
| 70 | Police & Firemen's Retirement System of New Jersey#70 · 15,793 sh | 15,793 | $64.9K | <0.01% | New |
| 71 | RAYMOND JAMES FINANCIAL#71 · 15,008 sh | 15,008 | $61.7K | 0.00% | -23.1% |
| 72 | NEW YORK STATE COMMON RETIREMENT FUND#72 · 14,500 sh | 14,500 | $59.6K | <0.01% | New |
| 73 | Vanguard Global Advisers#73 · 14,342 sh | 14,342 | $58.9K | 0.00% | -35.5% |
| 74 | OSAIC#74 · 13,900 sh | 13,900 | $57.1K | <0.01% | +531.8% |
| 75 | BARCLAYS PLC#75 · 13,357 sh | 13,357 | $54.9K | 0.00% | +603.0% |
| 76 | KESTRA PRIVATE WEALTH SERVICES#76 · 12,800 sh | 12,800 | $52.6K | <0.01% | 0.0% |
| 77 | Stokes Family Office#77 · 12,120 sh | 12,120 | $49.8K | <0.01% | 0.0% |
| 78 | Engineers Gate Manager#78 · 12,063 sh | 12,063 | $49.6K | <0.01% | New |
| 79 | First City Capital Management#79 · 11,836 sh | 11,836 | $48.6K | 0.02% | 0.0% |
| 80 | INTECH INVESTMENT MANAGEMENT#80 · 11,566 sh | 11,566 | $47.5K | <0.01% | New |
| 81 | STONERIDGE INVESTMENT PARTNERS#81 · 12,695 sh | 12,695 | $47.0K | 0.03% | New |
| 82 | VOYA INVESTMENT MANAGEMENT#82 · 11,017 sh | 11,017 | $45.3K | 0.00% | New |
| 83 | STRS OHIO#83 · 10,500 sh | 10,500 | $43.2K | <0.01% | New |
| 84 | Carolina Wealth Management#84 · 10,000 sh | 10,000 | $41.1K | 0.02% | — |
| 85 | Annandale Capital#85 · 10,000 sh | 10,000 | $41.0K | <0.01% | 0.0% |
| 86 | BNP PARIBAS FINANCIAL MARKETS#86 · 8,181 sh | 8,181 | $33.6K | 0.00% | New |
| 87 | Legal & General Group Plc#87 · 5,203 sh | 5,203 | $21.4K | 0.00% | New |
| 88 | Ameritas Investment Partners#88 · 4,860 sh | 4,860 | $20.0K | <0.01% | New |
| 89 | Hilton Head Capital Partners#89 · 4,472 sh | 4,472 | $18.4K | — | 0.0% |
| 90 | Russell Investments Group, Ltd.#90 · 4,282 sh | 4,282 | $17.6K | 0.00% | New |
| 91 | Farther Finance Advisors#91 · 3,490 sh | 3,490 | $14.3K | — | +51.7% |
| 92 | Tower Research Capital (TRC)#92 · 3,176 sh | 3,176 | $13.1K | <0.01% | -88.9% |
| 93 | TD Waterhouse Canada#93 · 3,000 sh | 3,000 | $12.5K | — | New |
| 94 | NATIONAL BANK OF CANADA#94 · 2,014 sh | 2,014 | $8.3K | 0.00% | 0.0% |
| 95 | ROYAL BANK OF CANADA#95 · 2,095 sh | 2,095 | $8.0K | 0.00% | New |
| 96 | GGM Financials#96 · 1,005 sh | 1,005 | $4.1K | <0.01% | New |
| 97 | INTERNATIONAL ASSETS INVESTMENT MANAGEMENT#97 · 521 sh | 521 | $2.2K | <0.01% | 0.0% |
| 98 | Quarry#98 · 502 sh | 502 | $2.1K | <0.01% | New |
| 99 | SBI Securities , Ltd.#99 · 501 sh | 501 | $2.1K | — | -5.5% |
| 100 | Sterling Capital Management#100 · 188 sh | 188 | $773.00 | — | New |
Funds that sold out of IRD in Q2 2026 (16)
Held IRD at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| PERCEPTIVE ADVISORS1,835,842 sh | 1,835,842 | $8.4M |
| FARALLON CAPITAL MANAGEMENT1,000,000 sh | 1,000,000 | $4.5M |
| AMERIPRISE FINANCIAL388,491 sh | 388,491 | $1.8M |
| Voleon Capital Management143,796 sh | 143,796 | $654.3K |
| RENAISSANCE TECHNOLOGIES73,209 sh | 73,209 | $333.1K |
| HRT FINANCIAL67,663 sh | 67,663 | $307.0K |
| Brevan Howard Capital Management61,313 sh | 61,313 | $279.0K |
| OMERS ADMINISTRATION41,600 sh | 41,600 | $189.3K |
| nVerses Capital28,564 sh | 28,564 | $130.0K |
| Persistent Asset Partners Ltd17,919 sh | 17,919 | $81.5K |
| Bedel Financial Consulting15,000 sh | 15,000 | $68.3K |
| BLAIR WILLIAM12,466 sh | 12,466 | $56.7K |
| SANDERS MORRIS HARRIS12,000 sh | 12,000 | $54.6K |
| GROUP ONE TRADING, L.P.10,594 sh | 10,594 | $48.2K |
| Reliant Investment Partners10,000 sh | 10,000 | $45.5K |
| Allworth Financial5 sh | 5 | $23.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.