CRISPR Therapeutics AG (CRSP) — Institutional Holders, Q2 2026

525 institutional investment managers reported a CRSP position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $4.2B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← CRSP stock profile

CRSP in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

158

Trimmed

141

Sold out

Biggest buyers

D. E. ShawNew · +893,812 sh+$48.7M
BlackRockAdded · +668,904 sh+$36.5M
TWO SIGMA INVESTMENTSAdded · +505,570 sh+$27.6M
STATE STREETAdded · +339,166 sh+$18.5M
Logos Global ManagementNew · +300,000 sh+$16.4M

Biggest sellers

ARK Investment ManagementTrimmed · -1,852,684 sh-$101.0M
LOOMIS SAYLES & L PSold out · -968,135 sh-$52.8M
T. Rowe Price Investment ManagementTrimmed · -899,578 sh-$49.1M
Orbis Allan Gray LtdTrimmed · -656,850 sh-$35.8M
UBS Group AGTrimmed · -445,031 sh-$24.3M

CRSP 13F holders ranked 1–100 of 525

Institutional investors reporting a position in CRISPR Therapeutics AG on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	ARK Investment Management#1 · 9,460,939 sh	9,460,939	$516.0M	3.35%	-16.4%
2	BlackRock#2 · 8,348,977 sh	8,348,977	$455.4M	<0.01%	+8.7%
3	Orbis Allan Gray Ltd#3 · 5,449,161 sh	5,449,161	$297.2M	1.02%	-10.8%
4	Capital World Investors#4 · 4,749,525 sh	4,749,525	$259.0M	0.03%	+0.5%
5	STATE STREET#5 · 4,321,666 sh	4,321,666	$235.7M	<0.01%	+8.5%
6	GSK plc#6 · 3,220,627 sh	3,220,627	$175.7M	29.17%	0.0%
7	GEODE CAPITAL MANAGEMENT#7 · 2,509,915 sh	2,509,915	$136.9M	<0.01%	+5.6%
8	T. Rowe Price Investment Management#8 · 2,053,017 sh	2,053,017	$112.0M	0.07%	-30.5%
9	SR ONE CAPITAL MANAGEMENT#9 · 2,038,763 sh	2,038,763	$111.2M	10.70%	0.0%
10	TWO SIGMA INVESTMENTS#10 · 1,988,621 sh	1,988,621	$108.5M	0.08%	+34.1%
11	FMR#11 · 1,908,503 sh	1,908,503	$104.1M	<0.01%	-2.4%
12	Sumitomo Mitsui#12 · 1,720,734 sh	1,720,734	$93.8M	0.05%	-7.2%
13	Nikko Asset Management Americas#13 · 1,720,097 sh	1,720,097	$93.8M	1.21%	-7.2%
14	EcoR1 Capital#14 · 1,389,276 sh	1,389,276	$75.8M	3.68%	0.0%
15	UBS Group AG#15 · 1,317,499 sh	1,317,499	$71.9M	<0.01%	-25.2%
16	Capital International Investors#16 · 1,268,407 sh	1,268,407	$69.2M	0.01%	+6.9%
17	VANGUARD CAPITAL MANAGEMENT#17 · 1,181,847 sh	1,181,847	$64.5M	<0.01%	+3.4%
18	BANK OF AMERICA#18 · 1,155,105 sh	1,155,105	$63.0M	<0.01%	+17.5%
19	NEA Management Company#19 · 1,058,570 sh	1,058,570	$57.7M	3.64%	0.0%
20	CHARLES SCHWAB INVESTMENT MANAGEMENT#20 · 1,057,837 sh	1,057,837	$57.7M	<0.01%	+1.8%
21	D. E. Shaw#21 · 893,812 sh	893,812	$48.7M	0.02%	New
22	MORGAN STANLEY#22 · 879,949 sh	879,949	$48.0M	<0.01%	+31.7%
23	NORTHERN#23 · 863,091 sh	863,091	$47.1M	<0.01%	+7.6%
24	VANGUARD PORTFOLIO MANAGEMENT#24 · 648,713 sh	648,713	$35.4M	<0.01%	+18.6%
25	VANGUARD FIDUCIARY#25 · 570,040 sh	570,040	$31.1M	<0.01%	+5.0%
26	CITADEL ADVISORS#26 · 465,796 sh	465,796	$25.4M	<0.01%	-9.8%
27	JPMORGAN CHASE#27 · 431,669 sh	431,669	$24.6M	<0.01%	-5.7%
28	SUSQUEHANNA INTERNATIONAL GROUP, LLP#28 · 427,178 sh	427,178	$23.3M	<0.01%	-28.0%
29	MILLENNIUM MANAGEMENT#29 · 382,032 sh	382,032	$20.8M	<0.01%	+1.3%
30	IQ EQ FUND MANAGEMENT (IRELAND) Ltd#30 · 381,991 sh	381,991	$20.8M	1.33%	-4.7%
31	Bank of New York Mellon#31 · 326,761 sh	326,761	$17.8M	<0.01%	+4.9%
32	Logos Global Management#32 · 300,000 sh	300,000	$16.4M	0.70%	New
33	Squarepoint Ops#33 · 286,789 sh	286,789	$15.6M	0.02%	+86.7%
34	Jump Financial#34 · 277,952 sh	277,952	$15.2M	0.12%	+158.7%
35	DIMENSIONAL FUND ADVISORS#35 · 275,375 sh	275,375	$15.0M	<0.01%	-44.3%
36	GOLDMAN SACHS GROUP#36 · 272,372 sh	272,372	$14.9M	<0.01%	-34.2%
37	NORGES BANK#37 · 270,756 sh	270,756	$14.8M	<0.01%	—
38	WELLS FARGO & COMPANY#38 · 263,169 sh	263,169	$14.4M	<0.01%	-6.2%
39	AMERIPRISE FINANCIAL#39 · 250,614 sh	250,614	$13.7M	<0.01%	-12.6%
40	Vestmark Advisory Solutions#40 · 242,266 sh	242,266	$13.2M	0.12%	-5.7%
41	RAYMOND JAMES FINANCIAL#41 · 231,988 sh	231,988	$12.7M	<0.01%	+5.3%
42	Nuveen#42 · 203,089 sh	203,089	$11.1M	<0.01%	+6.5%
43	ROYAL BANK OF CANADA#43 · 173,045 sh	173,045	$9.4M	<0.01%	+5.7%
44	Marex Group plc#44 · 170,584 sh	170,584	$9.3M	0.04%	+27.2%
45	Swiss National Bank#45 · 169,200 sh	169,200	$9.2M	<0.01%	-0.3%
46	Susquehanna Portfolio Strategies#46 · 164,026 sh	164,026	$8.9M	0.14%	+55.7%
47	Legal & General Group Plc#47 · 163,810 sh	163,810	$8.9M	<0.01%	+116.6%
48	LPL Financial#48 · 153,581 sh	153,581	$8.4M	<0.01%	+1.0%
49	Versant Venture Management#49 · 148,831 sh	148,831	$8.1M	4.99%	0.0%
50	Pictet Asset Management Holding SA#50 · 142,213 sh	142,213	$8.0M	<0.01%	-7.7%
51	Life Cycle Investment Partners Ltd#51 · 143,692 sh	143,692	$7.8M	0.04%	New
52	TD ASSET MANAGEMENT#52 · 142,602 sh	142,602	$7.8M	<0.01%	-10.0%
53	AMERICAN CENTURY COMPANIES#53 · 139,462 sh	139,462	$7.6M	<0.01%	+15.7%
54	HRT FINANCIAL#54 · 142,564 sh	142,564	$7.3M	0.02%	+102.1%
55	PRICE T ROWE ASSOCIATES#55 · 128,583 sh	128,583	$7.0M	<0.01%	+22.5%
56	MIRAE ASSET GLOBAL ETFS Ltd.#56 · 122,658 sh	122,658	$6.7M	<0.01%	+29.5%
57	RHUMBLINE ADVISERS#57 · 121,511 sh	121,511	$6.6M	<0.01%	+5.8%
58	KBC Group NV#58 · 116,847 sh	116,847	$6.4M	—	0.0%
59	CITIGROUP#59 · 114,316 sh	114,316	$6.2M	<0.01%	+420.3%
60	Private Advisor Group#60 · 111,129 sh	111,129	$6.1M	0.03%	+4.2%
61	EverSource Wealth Advisors#61 · 110,689 sh	110,689	$6.0M	0.20%	+4247.6%
62	CONGRESS ASSET MANAGEMENT#62 · 109,453 sh	109,453	$6.0M	—	+1.0%
63	Campbell & Investment Adviser#63 · 107,529 sh	107,529	$5.9M	0.31%	New
64	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM#64 · 102,669 sh	102,669	$5.6M	<0.01%	-11.6%
65	DEUTSCHE BANK AG\#65 · 101,854 sh	101,854	$5.6M	<0.01%	+22.2%
66	Rockefeller Capital Management L.P.#66 · 101,649 sh	101,649	$5.5M	<0.01%	+38.6%
67	Capital International Sarl#67 · 101,238 sh	101,238	$5.5M	0.08%	-1.0%
68	Affinity Asset Advisors#68 · 100,000 sh	100,000	$5.5M	0.25%	-33.3%
69	ALLIANCEBERNSTEIN L.P.#69 · 114,337 sh	114,337	$5.4M	<0.01%	+18.7%
70	CLOUGH CAPITAL PARTNERS L P#70 · 98,337 sh	98,337	$5.4M	0.44%	+298.4%
71	Zurcher Kantonalbank (Zurich Cantonalbank)#71 · 94,838 sh	94,838	$5.2M	<0.01%	+10.2%
72	Slow Capital#72 · 92,894 sh	92,894	$5.1M	—	+1.8%
73	Concurrent Investment Advisors#73 · 90,537 sh	90,537	$4.9M	—	+45.0%
74	CAPITAL FUND MANAGEMENT S.A.#74 · 89,242 sh	89,242	$4.9M	0.02%	-6.8%
75	VANGUARD ASSET MANAGEMENT, Ltd#75 · 86,550 sh	86,550	$4.7M	<0.01%	+12.6%
76	CREDIT AGRICOLE S A#76 · 85,930 sh	85,930	$4.7M	<0.01%	New
77	GROUP ONE TRADING, L.P.#77 · 85,040 sh	85,040	$4.6M	<0.01%	-11.4%
78	Himension Fund#78 · 83,897 sh	83,897	$4.6M	0.28%	-9.3%
79	STATE TREASURER STATE OF MICHIGAN#79 · 82,547 sh	82,547	$4.5M	—	New
80	OSAIC#80 · 79,501 sh	79,501	$4.3M	<0.01%	+32.4%
81	Fisher Asset Management#81 · 77,960 sh	77,960	$4.3M	<0.01%	New
82	Trexquant Investment#82 · 77,471 sh	77,471	$4.2M	0.02%	-39.1%
83	COMMONWEALTH EQUITY SERVICES#83 · 76,900 sh	76,900	$4.2M	<0.01%	-2.0%
84	Russell Investments Group, Ltd.#84 · 76,266 sh	76,266	$4.2M	<0.01%	+60.7%
85	JONES FINANCIAL COMPANIES LLLP#85 · 73,847 sh	73,847	$4.1M	<0.01%	+16.0%
86	Man Group plc#86 · 73,194 sh	73,194	$4.0M	<0.01%	-18.7%
87	ENVESTNET ASSET MANAGEMENT#87 · 70,081 sh	70,081	$3.8M	<0.01%	-14.7%
88	Shah Wealth Advisors#88 · 69,060 sh	69,060	$3.8M	0.87%	—
89	ALGERT GLOBAL#89 · 65,880 sh	65,880	$3.6M	0.04%	-32.0%
90	Invesco Ltd.#90 · 64,989 sh	64,989	$3.5M	<0.01%	+1.4%
91	RMB Capital Management#91 · 59,032 sh	59,032	$3.2M	0.05%	+18.8%
92	CAPITAL INTERNATIONAL LTD#92 · 56,066 sh	56,066	$3.1M	0.10%	0.0%
93	NOMURA#93 · 56,027 sh	56,027	$3.1M	<0.01%	+962.5%
94	Rafferty Asset Management#94 · 55,833 sh	55,833	$3.0M	<0.01%	-38.2%
95	Green Alpha Advisors#95 · 55,804 sh	55,804	$3.0M	—	-2.1%
96	BENJAMIN EDWARDS#96 · 54,488 sh	54,488	$3.0M	0.03%	-1.8%
97	MetLife Investment Management#97 · 54,243 sh	54,243	$3.0M	0.01%	+9.3%
98	Quantinno Capital Management#98 · 52,610 sh	52,610	$2.9M	<0.01%	+9.6%
99	Cetera Investment Advisers#99 · 52,368 sh	52,368	$2.9M	<0.01%	-11.6%
100	STATE OF WISCONSIN INVESTMENT BOARD#100 · 51,128 sh	51,128	$2.8M	<0.01%	-2.7%

Funds that sold out of CRSP in Q2 2026 (48)

Held CRSP at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held CRSP in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
LOOMIS SAYLES & L P968,135 sh	968,135	$46.1M
Baker Chad R93,300 sh	93,300	$4.4M
VAN ECK ASSOCIATES85,294 sh	85,294	$4.1M
Monashee Investment Management50,000 sh	50,000	$2.4M
READYSTATE ASSET MANAGEMENT20,933 sh	20,933	$995.8K
Orion Porfolio Solutions13,270 sh	13,270	$631.3K
Virtu Financial11,590 sh	11,590	$551.0K
GSA CAPITAL PARTNERS LLP9,711 sh	9,711	$462.0K
NWAM9,173 sh	9,173	$436.4K
GFS Advisors12,500 sh	12,500	$427.3K
Amundi8,262 sh	8,262	$393.0K
ALPINE WOODS CAPITAL INVESTORS8,220 sh	8,220	$391.0K
Formidable Asset Management7,298 sh	7,298	$382.7K
GTS SECURITIES7,787 sh	7,787	$370.4K
INCEPTIONR6,577 sh	6,577	$312.9K
BOURGEON CAPITAL MANAGEMENT5,600 sh	5,600	$266.4K
Vanguard Personalized Indexing Management5,073 sh	5,073	$241.3K
Ausdal Financial Partners4,862 sh	4,862	$231.3K
MONEY CONCEPTS CAPITAL4,738 sh	4,738	$225.4K
SummitTX Capital, L.P.4,448 sh	4,448	$211.6K
SIG BROKERAGE4,326 sh	4,326	$205.8K
Whipplewood Advisors3,392 sh	3,392	$161.4K
HSBC PLC2,787 sh	2,787	$130.6K
Western Wealth Management1,967 sh	1,967	$93.6K
Neo Ivy Capital Management1,725 sh	1,725	$82.1K
WOLVERINE ASSET MANAGEMENT1,521 sh	1,521	$72.4K
SIMPLEX TRADING1,407 sh	1,407	$66.9K
PITTENGER & ANDERSON1,325 sh	1,325	$63.0K
QUADRANT CAPITAL GROUP316 sh	316	$56.5K
Opal Wealth Advisors681 sh	681	$32.4K
Align Financial250 sh	250	$11.9K
CHESAPEAKE ASSET MANAGEMENT200 sh	200	$9.5K
Sound Income Strategies127 sh	127	$6.2K
Financial Freedom100 sh	100	$4.8K
BankPlus Department100 sh	100	$4.8K
Hamrick Investment Counsel80 sh	80	$3.8K
Golden State Equity Partners41 sh	41	$1.9K
MATHER GROUP35 sh	35	$1.7K
ARMSTRONG ADVISORY GROUP31 sh	31	$1.5K
Signature Equity Partners24 sh	24	$1.1K
Vanguard National20 sh	20	$951.00
Root Financial Partners15 sh	15	$714.00
MBM WEALTH CONSULTANTS10 sh	10	$476.00
Cornerstone Financial Management9 sh	9	$428.00
Kilter Group6 sh	6	$286.00
Legacy Wealth Managment4 sh	4	$191.00
Ronald Blue4 sh	4	$190.00
TWIN PEAKS WEALTH ADVISORS4 sh	4	$190.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.