Caribou Biosciences, Inc. (CRBU) — Institutional Holders, Q2 2026
137 institutional investment managers reported a CRBU position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $84.8M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
CRBU in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- BlackRockAdded · +5,672,758 sh+$10.0M
- MACKENZIE FINANCIALAdded · +2,708,010 sh+$4.8M
- GEODE CAPITAL MANAGEMENTAdded · +1,356,935 sh+$2.4M
- STATE STREETAdded · +1,209,651 sh+$2.1M
- ACADIAN ASSET MANAGEMENTAdded · +849,435 sh+$1.5M
Biggest sellers
- abrdn plcSold out · -1,212,541 sh-$2.1M
- MILLENNIUM MANAGEMENTTrimmed · -1,023,250 sh-$1.8M
- MARSHALL WACE, LLPTrimmed · -829,982 sh-$1.5M
- TWO SIGMA INVESTMENTSTrimmed · -713,655 sh-$1.3M
- SUSQUEHANNA INTERNATIONAL GROUP, LLPTrimmed · -671,489 sh-$1.2M
CRBU 13F holders ranked 1–100 of 137
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | BlackRock#1 · 7,815,843 sh | 7,815,843 | $13.8M | <0.01% | +264.7% |
| 2 | PFIZER#2 · 4,690,431 sh | 4,690,431 | $7.9M | 4.63% | 0.0% |
| 3 | VANGUARD CAPITAL MANAGEMENT#3 · 4,208,568 sh | 4,208,568 | $7.4M | <0.01% | +11.7% |
| 4 | MACKENZIE FINANCIAL#4 · 3,650,796 sh | 3,650,796 | $6.4M | <0.01% | +287.2% |
| 5 | RENAISSANCE TECHNOLOGIES#5 · 2,773,545 sh | 2,773,545 | $4.9M | <0.01% | +7.1% |
| 6 | Kynam Capital Management#6 · 2,503,302 sh | 2,503,302 | $4.4M | 0.24% | 0.0% |
| 7 | GEODE CAPITAL MANAGEMENT#7 · 2,374,894 sh | 2,374,894 | $4.2M | <0.01% | +133.3% |
| 8 | ACADIAN ASSET MANAGEMENT#8 · 1,774,474 sh | 1,774,474 | $3.1M | <0.01% | +91.8% |
| 9 | STATE STREET#9 · 1,632,914 sh | 1,632,914 | $2.9M | <0.01% | +285.8% |
| 10 | BANK OF AMERICA#10 · 1,410,958 sh | 1,410,958 | $2.5M | <0.01% | +8.8% |
| 11 | TWO SIGMA INVESTMENTS#11 · 1,046,279 sh | 1,046,279 | $1.8M | <0.01% | -40.6% |
| 12 | DIMENSIONAL FUND ADVISORS#12 · 975,327 sh | 975,327 | $1.7M | <0.01% | +44.9% |
| 13 | CHARLES SCHWAB INVESTMENT MANAGEMENT#13 · 775,809 sh | 775,809 | $1.4M | <0.01% | +38.6% |
| 14 | FMR#14 · 727,115 sh | 727,115 | $1.3M | <0.01% | +0.4% |
| 15 | NORTHERN#15 · 712,965 sh | 712,965 | $1.3M | <0.01% | +227.4% |
| 16 | MAVERICK CAPITAL LTD#16 · 652,542 sh | 652,542 | $1.1M | 0.01% | 0.0% |
| 17 | VANGUARD PORTFOLIO MANAGEMENT#17 · 613,801 sh | 613,801 | $1.1M | 0.00% | New |
| 18 | VANGUARD FIDUCIARY#18 · 606,388 sh | 606,388 | $1.1M | <0.01% | +16.6% |
| 19 | Qube Research & Technologies Ltd#19 · 545,755 sh | 545,755 | $960.5K | <0.01% | +208.9% |
| 20 | UBS Group AG#20 · 517,371 sh | 517,371 | $910.6K | <0.01% | +99.6% |
| 21 | 72 Investment#21 · 474,067 sh | 474,067 | $834.4K | 1.67% | 0.0% |
| 22 | GSA CAPITAL PARTNERS LLP#22 · 463,416 sh | 463,416 | $816.0K | 0.05% | -3.6% |
| 23 | JACOBS LEVY EQUITY MANAGEMENT#23 · 410,979 sh | 410,979 | $723.3K | <0.01% | +14.5% |
| 24 | Cambridge Investment Research Advisors#24 · 382,410 sh | 382,410 | $673.0K | <0.01% | -30.1% |
| 25 | MARSHALL WACE, LLP#25 · 375,686 sh | 375,686 | $661.2K | <0.01% | -68.8% |
| 26 | Green Alpha Advisors#26 · 364,324 sh | 364,324 | $641.2K | — | -2.5% |
| 27 | PFM Health Sciences#27 · 354,687 sh | 354,687 | $624.2K | 0.05% | -63.0% |
| 28 | GOLDMAN SACHS GROUP#28 · 322,875 sh | 322,875 | $568.3K | 0.00% | -14.3% |
| 29 | Invesco Ltd.#29 · 301,117 sh | 301,117 | $530.0K | 0.00% | +260.6% |
| 30 | WELLS FARGO & COMPANY#30 · 298,315 sh | 298,315 | $525.0K | <0.01% | -1.8% |
| 31 | XTX Topco Ltd#31 · 269,157 sh | 269,157 | $473.7K | <0.01% | -16.8% |
| 32 | Bruce#32 · 250,000 sh | 250,000 | $440.0K | 0.12% | 0.0% |
| 33 | Man Group plc#33 · 240,066 sh | 240,066 | $422.5K | <0.01% | +210.9% |
| 34 | Bank of New York Mellon#34 · 222,560 sh | 222,560 | $391.7K | <0.01% | +1678.9% |
| 35 | MILESTONE ASSET MANAGEMENT#35 · 200,085 sh | 200,085 | $352.1K | — | +23.5% |
| 36 | MIRAE ASSET GLOBAL ETFS Ltd.#36 · 173,375 sh | 173,375 | $305.1K | <0.01% | +95.9% |
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#37 · 165,414 sh | 165,414 | $291.1K | 0.00% | -80.2% |
| 38 | Susquehanna Portfolio Strategies#38 · 158,597 sh | 158,597 | $279.1K | <0.01% | New |
| 39 | Graham Capital Management, L.P.#39 · 155,914 sh | 155,914 | $274.4K | <0.01% | +302.3% |
| 40 | AMERICAN CENTURY COMPANIES#40 · 140,580 sh | 140,580 | $247.4K | <0.01% | +25.0% |
| 41 | BRIDGEWAY CAPITAL MANAGEMENT#41 · 132,000 sh | 132,000 | $232.3K | <0.01% | 0.0% |
| 42 | Nuveen#42 · 123,516 sh | 123,516 | $217.4K | <0.01% | New |
| 43 | LPL Financial#43 · 122,774 sh | 122,774 | $216.1K | 0.00% | +248.1% |
| 44 | MORGAN STANLEY#44 · 121,320 sh | 121,320 | $213.5K | 0.00% | -50.5% |
| 45 | NANO CAP NEW MILLENNIUM GROWTH FUND L P#45 · 117,500 sh | 117,500 | $206.8K | 0.16% | 0.0% |
| 46 | DEUTSCHE BANK AG\#46 · 89,575 sh | 89,575 | $157.7K | 0.00% | New |
| 47 | Quadrature Capital Ltd#47 · 88,979 sh | 88,979 | $156.6K | <0.01% | +124.9% |
| 48 | CANADA PENSION PLAN INVESTMENT BOARD#48 · 81,100 sh | 81,100 | $142.7K | <0.01% | +40.1% |
| 49 | Keystone Financial Group#49 · 80,825 sh | 80,825 | $142.3K | <0.01% | +0.4% |
| 50 | BNP PARIBAS FINANCIAL MARKETS#50 · 70,896 sh | 70,896 | $124.8K | 0.00% | +3205.2% |
| 51 | RHUMBLINE ADVISERS#51 · 68,571 sh | 68,571 | $120.7K | <0.01% | New |
| 52 | CITIGROUP#52 · 61,311 sh | 61,311 | $107.9K | 0.00% | +7.7% |
| 53 | Nelson Capital Management#53 · 58,685 sh | 58,685 | $103.3K | 0.01% | 0.0% |
| 54 | MILLENNIUM MANAGEMENT#54 · 51,171 sh | 51,171 | $90.1K | 0.00% | -95.2% |
| 55 | BARCLAYS PLC#55 · 50,312 sh | 50,312 | $88.5K | 0.00% | +88.3% |
| 56 | COMMONWEALTH EQUITY SERVICES#56 · 47,908 sh | 47,908 | $84.3K | <0.01% | +6.7% |
| 57 | Virtu Financial#57 · 45,188 sh | 45,188 | $80.0K | <0.01% | +23.4% |
| 58 | JPMORGAN CHASE#58 · 42,929 sh | 42,929 | $76.0K | 0.00% | +605.0% |
| 59 | SEI INVESTMENTS#59 · 41,939 sh | 41,939 | $73.8K | <0.01% | +35.3% |
| 60 | CITADEL ADVISORS#60 · 40,415 sh | 40,415 | $71.1K | 0.00% | -74.6% |
| 61 | ALLIANCEBERNSTEIN L.P.#61 · 37,080 sh | 37,080 | $70.5K | 0.00% | New |
| 62 | RBF Capital#62 · 40,000 sh | 40,000 | $70.4K | <0.01% | 0.0% |
| 63 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO#63 · 39,129 sh | 39,129 | $68.9K | <0.01% | 0.0% |
| 64 | Russell Investments Group, Ltd.#64 · 37,380 sh | 37,380 | $65.8K | <0.01% | +35.6% |
| 65 | Connor, Clark & Lunn Investment Management Ltd.#65 · 35,513 sh | 35,513 | $62.5K | <0.01% | +15.5% |
| 66 | NEW YORK STATE COMMON RETIREMENT FUND#66 · 35,400 sh | 35,400 | $62.3K | <0.01% | New |
| 67 | HSBC PLC#67 · 34,460 sh | 34,460 | $61.9K | 0.00% | 0.0% |
| 68 | Vanguard Personalized Indexing Management#68 · 34,715 sh | 34,715 | $61.1K | <0.01% | -11.5% |
| 69 | PRUDENTIAL FINANCIAL#69 · 34,375 sh | 34,375 | $60.5K | <0.01% | +80.9% |
| 70 | US BANCORP \DE\#70 · 34,265 sh | 34,265 | $60.3K | <0.01% | 0.0% |
| 71 | WILEY BROS.-AINTREE CAPITAL#71 · 32,505 sh | 32,505 | $57.2K | <0.01% | 0.0% |
| 72 | Prime Capital Investment Advisors#72 · 32,315 sh | 32,315 | $56.9K | — | 0.0% |
| 73 | Thrive Wealth Management#73 · 32,000 sh | 32,000 | $56.3K | — | 0.0% |
| 74 | JANE STREET GROUP#74 · 30,331 sh | 30,331 | $53.4K | 0.00% | +21.4% |
| 75 | AMERIPRISE FINANCIAL#75 · 29,530 sh | 29,530 | $52.0K | 0.00% | +0.3% |
| 76 | Vanguard Global Advisers#76 · 29,101 sh | 29,101 | $51.2K | 0.00% | 0.0% |
| 77 | CREDIT AGRICOLE S A#77 · 29,000 sh | 29,000 | $51.0K | <0.01% | 0.0% |
| 78 | Police & Firemen's Retirement System of New Jersey#78 · 27,084 sh | 27,084 | $47.7K | <0.01% | New |
| 79 | BANK OF MONTREAL#79 · 26,500 sh | 26,500 | $46.6K | 0.00% | +26.2% |
| 80 | Creative Planning#80 · 25,500 sh | 25,500 | $44.9K | 0.00% | +54.5% |
| 81 | Spark Investment Management#81 · 23,600 sh | 23,600 | $41.5K | 0.08% | New |
| 82 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#82 · 23,464 sh | 23,464 | $41.3K | 0.00% | New |
| 83 | LIBERTY WEALTH MANAGEMENT#83 · 19,500 sh | 19,500 | $37.0K | <0.01% | 0.0% |
| 84 | RAYMOND JAMES FINANCIAL#84 · 20,534 sh | 20,534 | $36.1K | 0.00% | +25.4% |
| 85 | Next Capital Management#85 · 20,000 sh | 20,000 | $35.2K | <0.01% | 0.0% |
| 86 | INTECH INVESTMENT MANAGEMENT#86 · 19,870 sh | 19,870 | $35.0K | <0.01% | New |
| 87 | HighTower Advisors#87 · 16,934 sh | 16,934 | $29.8K | 0.00% | 0.0% |
| 88 | China Universal Asset Management , Ltd.#88 · 15,785 sh | 15,785 | $27.8K | <0.01% | -4.8% |
| 89 | Point72 Asset Management, L.P.#89 · 15,769 sh | 15,769 | $27.8K | 0.00% | -91.6% |
| 90 | ProShare Advisors#90 · 15,279 sh | 15,279 | $26.9K | 0.00% | New |
| 91 | Modern Wealth Management#91 · 15,000 sh | 15,000 | $26.4K | <0.01% | 0.0% |
| 92 | GREAT VALLEY ADVISOR GROUP#92 · 14,314 sh | 14,314 | $25.2K | <0.01% | 0.0% |
| 93 | Pinnacle Wealth Management Advisory Group#93 · 12,903 sh | 12,903 | $22.7K | — | 0.0% |
| 94 | PINNACLE ASSOCIATES LTD#94 · 12,903 sh | 12,903 | $22.7K | — | 0.0% |
| 95 | AXQ CAPITAL#95 · 12,249 sh | 12,249 | $21.6K | <0.01% | -18.3% |
| 96 | WEALTH ENHANCEMENT ADVISORY SERVICES#96 · 11,008 sh | 11,008 | $21.2K | — | New |
| 97 | HBK Sorce Advisory#97 · 12,344 sh | 12,344 | $19.9K | <0.01% | 0.0% |
| 98 | J.W. COLE ADVISORS#98 · 11,269 sh | 11,269 | $19.8K | <0.01% | New |
| 99 | Naviter Wealth#99 · 11,091 sh | 11,091 | $19.5K | <0.01% | New |
| 100 | NewEdge Advisors#100 · 10,925 sh | 10,925 | $19.2K | <0.01% | New |
Funds that sold out of CRBU in Q2 2026 (22)
Held CRBU at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| abrdn plc1,212,541 sh | 1,212,541 | $2.3M |
| OMERS ADMINISTRATION120,200 sh | 120,200 | $228.4K |
| HRT FINANCIAL78,954 sh | 78,954 | $150.0K |
| Brevan Howard Capital Management65,062 sh | 65,062 | $123.6K |
| LEUCADIA NATIONAL33,262 sh | 33,262 | $63.2K |
| Diametric Capital32,793 sh | 32,793 | $62.3K |
| Catalyst Funds Management Pty Ltd32,200 sh | 32,200 | $61.2K |
| ENVESTNET ASSET MANAGEMENT30,586 sh | 30,586 | $58.1K |
| Schonfeld Strategic Advisors23,969 sh | 23,969 | $45.5K |
| NINE MASTS CAPITAL Ltd20,612 sh | 20,612 | $39.2K |
| Westmount Partners19,609 sh | 19,609 | $37.3K |
| AQR CAPITAL MANAGEMENT15,678 sh | 15,678 | $29.8K |
| Bronte Capital Management Pty Ltd.15,627 sh | 15,627 | $29.7K |
| CTC Alternative Strategies, Ltd.15,076 sh | 15,076 | $28.6K |
| Cetera Investment Advisers14,781 sh | 14,781 | $28.1K |
| TWO SIGMA SECURITIES13,052 sh | 13,052 | $24.8K |
| Jump Financial12,460 sh | 12,460 | $23.7K |
| Allworth Financial9,430 sh | 9,430 | $17.9K |
| Scarborough Advisors8,420 sh | 8,420 | $16.0K |
| SUMMIT SECURITIES GROUP809 sh | 809 | $1.5K |
| Signature Equity Partners177 sh | 177 | $336.00 |
| Advisory Services Network114 sh | 114 | $217.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.