AYTU BIOPHARMA, INC (AYTU) — Institutional Holders, Q2 2026

38 institutional investment managers reported a AYTU position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $15.9M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

AYTU in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

3

Added to

11

Trimmed

5

Sold out

2

Biggest buyers

  1. Stonepine Capital ManagementAdded · +4,197,949 sh+$9.0M
  2. CROWN ADVISORS MANAGEMENTAdded · +55,000 sh+$118.3K
  3. CITADEL ADVISORSAdded · +12,573 sh+$27.0K
  4. RENAISSANCE TECHNOLOGIESAdded · +11,100 sh+$23.9K
  5. NORTHERNAdded · +8,756 sh+$18.8K

Biggest sellers

  1. DIADEMA PARTNERSTrimmed · -204,531 sh-$439.7K
  2. Persistent Asset Partners LtdTrimmed · -54,913 sh-$118.1K
  3. TWO SIGMA INVESTMENTSTrimmed · -16,647 sh-$35.8K
  4. MAI Capital ManagementSold out · -3,575 sh-$7.7K
  5. XTX Topco LtdTrimmed · -166 sh-$357.00

AYTU 13F holders ranked 1–38 of 38

Institutional investors reporting a position in AYTU BIOPHARMA, INC on SEC Form 13F-HR for Q2 2026, ranked by reported value.
InstitutionValueQoQ
Stonepine Capital Management#1 · 4,990,238 sh$9.6M+529.9%
Nantahala Capital Management#2 · 1,086,812 sh$2.3M0.0%
AWM Investment Company#3 · 619,574 sh$1.3M0.0%
VANGUARD CAPITAL MANAGEMENT#4 · 261,146 sh$561.5K0.0%
CROWN ADVISORS MANAGEMENT#5 · 200,000 sh$430.0K+37.9%
DIADEMA PARTNERS#6 · 148,546 sh$319.4K-57.9%
TWO SIGMA INVESTMENTS#7 · 105,326 sh$226.5K-13.6%
RENAISSANCE TECHNOLOGIES#8 · 104,823 sh$225.4K+11.8%
GEODE CAPITAL MANAGEMENT#9 · 93,647 sh$201.4K+1.1%
CITADEL ADVISORS#10 · 49,414 sh$106.2K+34.1%
VANGUARD FIDUCIARY#11 · 47,048 sh$101.2K0.0%
DIMENSIONAL FUND ADVISORS#12 · 45,326 sh$97.5K+4.0%
Persistent Asset Partners Ltd#13 · 37,984 sh$81.7K-59.1%
NORTHERN#14 · 27,925 sh$60.0K+45.7%
BELLEVUE ASSET MANAGEMENT#15 · 25,013 sh$53.8K0.0%
BlackRock#16 · 22,793 sh$49.0K0.0%
XTX Topco Ltd#17 · 21,416 sh$46.0K-0.8%
Daytona Street Capital#18 · 10,000 sh$22.4K0.0%
ACADIAN ASSET MANAGEMENT#19 · 10,237 sh$22.0K0.0%
UBS Group AG#20 · 2,377 sh$5.1K+42.9%
Tower Research Capital (TRC)#21 · 2,232 sh$4.8K+42.7%
ROYAL BANK OF CANADA#22 · 378 sh$1.0K+950.0%
OSAIC#23 · 462 sh$991.000.0%
JPMORGAN CHASE#24 · 154 sh$337.000.0%
WELLS FARGO & COMPANY#25 · 127 sh$273.000.0%
MORGAN STANLEY#26 · 125 sh$269.000.0%
BARCLAYS PLC#27 · 50 sh$108.00New
GROUP ONE TRADING, L.P.#28 · 37 sh$80.000.0%
BNP PARIBAS FINANCIAL MARKETS#29 · 23 sh$49.000.0%
Rockefeller Capital Management L.P.#30 · 10 sh$22.000.0%
SBI Securities , Ltd.#31 · 10 sh$22.00-9.1%
Farther Finance Advisors#32 · 4 sh$9.00New
VISION FINANCIAL MARKETS#33 · 2 sh$5.000.0%
SRS Capital Advisors#34 · 2 sh$4.00New
Caitong International Asset Management , Ltd#35 · 2 sh$4.000.0%
JONES FINANCIAL COMPANIES LLLP#36 · 1 sh$2.000.0%
FNY Investment Advisers#37 · 110 sh$0.00+22.2%
TSFG#38 · 1 sh$0.000.0%

Funds that sold out of AYTU in Q2 2026 (2)

Held AYTU at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held AYTU in Q1 2026 and reported no position in Q2 2026.
InstitutionValue in Q1 2026
Arete Wealth Advisors49,549 sh$4.0M
MAI Capital Management3,575 sh$9.8K

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.