AYTU BIOPHARMA, INC(AYTU)— Stock Profile, AI Score & Financials

Healthcare · Nasdaq · AI-powered stock analysis, 32-signal quality score, SEC EDGAR financials, and institutional holdings. Updated .

AYTU BIOPHARMA, INC (AYTU) stock profile, AI quality score, and SEC EDGAR financial data, a Healthcare sector company. 13F Pro's AI-powered ranking engine scores AYTU at 23.4/100 on a 32-signal composite quality model, placing it at rank #2,727 of 2,962 stocks — the bottom half of the AI-ranked universe. AYTU scores in the top quartile across institutional flow (99.5). Areas of concern include revenue growth (6.8) and balance sheet strength (8.1), which score below median versus the broader universe. Based on the latest XBRL financial filings (Q1 2026), AYTU BIOPHARMA, INC reports quarterly revenue of $12.4M, net income of $-5.6M, an operating margin of -32.8%. Top institutional holders of AYTU by reported 13-F value include Stonepine Capital Management, Nantahala Capital Management, AWM Investment Company, based on the most recent SEC filings. AYTU trades on the Nasdaq exchange and files with the SEC under CIK 1385818. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate AYTU daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for AYTU BIOPHARMA, INC directly from SEC EDGAR.

AI Quality Score

23.4/100

AI Rank

#2,727

Revenue

$12.4M

Net Income

$-5.6M

Free Cash Flow

$-4.2M

Operating Margin

-32.8%

AYTU key financials by period

AYTU BIOPHARMA, INC reported revenue, net income and margins by fiscal period, from SEC filings.
PeriodFormRevenueNet incomeOperating margin
FY 202510-K$66.4M$-13.6M-11.8%
FY 202410-K$65.2M$-15.8M-2.4%
FY 202310-K$107.4M$-17.1M-15.9%
FY 202210-K$96.7M$-108.8M-113.7%
FY 202110-K$65.6M$-58.3M-89.7%
FY 202010-K$27.6M$-13.6M-76.5%

Institutions holding AYTU

Institutional investors reporting a position in AYTU BIOPHARMA, INC on SEC Form 13F.
InstitutionSharesValueReported
Stonepine Capital Management4,990,238$9.6M2026-06-30
Nantahala Capital Management1,086,812$2.3M2026-06-30
AWM Investment Company619,574$1.3M2026-06-30
VANGUARD CAPITAL MANAGEMENT261,146$561.5K2026-06-30
CROWN ADVISORS MANAGEMENT200,000$430.0K2026-06-30
DIADEMA PARTNERS148,546$319.4K2026-06-30
TWO SIGMA INVESTMENTS105,326$226.5K2026-06-30
RENAISSANCE TECHNOLOGIES104,823$225.4K2026-06-30
GEODE CAPITAL MANAGEMENT93,647$201.4K2026-06-30
CITADEL ADVISORS49,414$106.2K2026-06-30
AYTU

AYTU BIOPHARMA, INC

AYTU
NasdaqSmall CapHealthcare

13F Pro Quality Score

23.4/100

Rank #2,727 of 2,962 stocks

View Healthcare peers →

Rankings refresh quarterly once 80% of peers have filed (~45 days after quarter-end). Next update: ~Nov 14, 2026.

Revenue Growth

6.8/100

Profitability

9.2/100

Balance Sheet

8.1/100

Earnings Quality

48.2/100

Free Cash Flow

35.3/100

Institutional Flow

99.5/100

Revenue Scale

9.9/100

Dilution Risk

61.2/100

Price Chart

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Key Metrics

Revenue

Q1 2026
EDGAR

$12.41M

Net Income

Q1 2026
EDGAR

$-5.62M

EPS (Diluted)

Q1 2026
EDGAR

$-0.53

Operating Margin

Q1 2026
EDGAR

-32.8%

ROIC

Q1 2026
EDGAR

-33.6%

Free Cash Flow

Q1 2026
EDGAR

$-4.18M

Debt/Equity

Q1 2026
EDGAR

0.38

Top Institutional Holders

as of Q2 2026
$15.91M total

Financial Trends

Revenue & Net Income

Earnings Per Share

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