Axsome Therapeutics, Inc. (AXSM) — Institutional Holders, Q2 2026

508 institutional investment managers reported a AXSM position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $9.3B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← AXSM stock profile

AXSM in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

130

Added to

160

Trimmed

158

Sold out

Biggest buyers

MILLENNIUM MANAGEMENTAdded · +535,330 sh+$131.0M
JANE STREET GROUPAdded · +399,917 sh+$97.9M
Invesco Ltd.Added · +374,006 sh+$91.5M
TWO SIGMA INVESTMENTSAdded · +346,700 sh+$84.9M
MORGAN STANLEYAdded · +327,381 sh+$80.1M

Biggest sellers

BlackRockTrimmed · -809,136 sh-$198.1M
PRICE T ROWE ASSOCIATESTrimmed · -674,166 sh-$165.0M
WELLINGTON MANAGEMENT GROUP LLPTrimmed · -491,386 sh-$120.3M
ADAGE CAPITAL PARTNERS GP, L.L.C.Trimmed · -478,544 sh-$117.1M
Assenagon Asset Management S.A.Trimmed · -411,276 sh-$100.7M

AXSM 13F holders ranked 1–100 of 508

Institutional investors reporting a position in Axsome Therapeutics, Inc. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	BlackRock#1 · 3,103,708 sh	3,103,708	$759.7M	0.01%	-20.7%
2	VANGUARD PORTFOLIO MANAGEMENT#2 · 1,983,514 sh	1,983,514	$485.5M	0.02%	-3.6%
3	VANGUARD CAPITAL MANAGEMENT#3 · 1,965,086 sh	1,965,086	$481.0M	0.01%	+1.4%
4	Invesco Ltd.#4 · 1,671,684 sh	1,671,684	$409.2M	0.03%	+28.8%
5	FMR#5 · 1,539,163 sh	1,539,163	$376.7M	0.02%	-1.8%
6	GEODE CAPITAL MANAGEMENT#6 · 967,172 sh	967,172	$236.8M	0.01%	-16.8%
7	MORGAN STANLEY#7 · 804,082 sh	804,082	$196.8M	0.01%	+68.7%
8	STATE STREET#8 · 785,661 sh	785,661	$192.3M	<0.01%	-20.4%
9	Deep Track Capital#9 · 700,000 sh	700,000	$171.3M	2.49%	-36.4%
10	TWO SIGMA INVESTMENTS#10 · 669,478 sh	669,478	$163.9M	0.12%	+107.4%
11	FRANKLIN RESOURCES#11 · 668,373 sh	668,373	$163.6M	0.04%	+52.4%
12	WELLINGTON MANAGEMENT GROUP LLP#12 · 653,920 sh	653,920	$160.1M	0.03%	-42.9%
13	ALETHEA CAPITAL MANAGEMENT#13 · 648,756 sh	648,756	$158.8M	65.78%	-0.1%
14	PRICE T ROWE ASSOCIATES#14 · 642,893 sh	642,893	$157.4M	0.02%	-51.2%
15	D. E. Shaw#15 · 604,753 sh	604,753	$148.0M	0.07%	+0.2%
16	MILLENNIUM MANAGEMENT#16 · 556,088 sh	556,088	$136.1M	0.05%	+2578.9%
17	NOMURA ASSET MANAGEMENT INTERNATIONAL#17 · 539,407 sh	539,407	$132.0M	0.20%	-33.6%
18	NORGES BANK#18 · 514,266 sh	514,266	$125.9M	0.01%	—
19	FIRST ADVISORS#19 · 482,061 sh	482,061	$118.0M	0.07%	-16.5%
20	Assenagon Asset Management S.A.#20 · 454,682 sh	454,682	$111.3M	—	-47.5%
21	BANK OF AMERICA#21 · 452,491 sh	452,491	$110.8M	<0.01%	-24.3%
22	AMERIPRISE FINANCIAL#22 · 428,079 sh	428,079	$104.8M	0.02%	+142.8%
23	Pictet Asset Management Holding SA#23 · 426,527 sh	426,527	$104.4M	0.10%	+2.5%
24	Qube Research & Technologies Ltd#24 · 426,336 sh	426,336	$104.4M	0.10%	+27.1%
25	Point72 Asset Management, L.P.#25 · 416,516 sh	416,516	$102.0M	0.11%	-1.9%
26	JANE STREET GROUP#26 · 403,995 sh	403,995	$98.9M	<0.01%	+9806.7%
27	Hood River Capital Management#27 · 402,678 sh	402,678	$98.6M	0.71%	+8.4%
28	HEALTHCARE OF ONTARIO PENSION PLAN FUND#28 · 373,067 sh	373,067	$91.3M	0.13%	+282.4%
29	DRIEHAUS CAPITAL MANAGEMENT#29 · 372,474 sh	372,474	$91.2M	0.53%	+27.4%
30	PRINCIPAL FINANCIAL GROUP#30 · 332,642 sh	332,642	$81.4M	0.04%	-5.1%
31	EVENTIDE ASSET MANAGEMENT#31 · 316,820 sh	316,820	$77.5M	1.04%	-39.0%
32	CHARLES SCHWAB INVESTMENT MANAGEMENT#32 · 316,104 sh	316,104	$77.4M	0.01%	-20.0%
33	Integral Health Asset Management#33 · 300,000 sh	300,000	$73.4M	2.90%	+757.1%
34	VANGUARD FIDUCIARY#34 · 279,738 sh	279,738	$68.5M	0.02%	-5.2%
35	NORTHERN#35 · 270,189 sh	270,189	$66.1M	<0.01%	-32.7%
36	RENAISSANCE TECHNOLOGIES#36 · 262,000 sh	262,000	$64.1M	0.09%	+59.5%
37	ADAGE CAPITAL PARTNERS GP, L.L.C.#37 · 259,034 sh	259,034	$63.4M	0.09%	-64.9%
38	CITADEL ADVISORS#38 · 255,878 sh	255,878	$62.6M	<0.01%	-9.1%
39	FRONTIER CAPITAL MANAGEMENT#39 · 254,280 sh	254,280	$62.2M	0.58%	+25.2%
40	SAMLYN CAPITAL#40 · 246,015 sh	246,015	$60.2M	0.98%	New
41	Clearbridge Investments#41 · 245,574 sh	245,574	$60.1M	0.05%	+445.5%
42	LOOMIS SAYLES & L P#42 · 239,490 sh	239,490	$58.6M	0.07%	-6.7%
43	BNP PARIBAS FINANCIAL MARKETS#43 · 230,954 sh	230,954	$56.5M	0.02%	+22.8%
44	GOLDMAN SACHS GROUP#44 · 229,668 sh	229,668	$56.2M	<0.01%	-45.5%
45	CANADA PENSION PLAN INVESTMENT BOARD#45 · 225,400 sh	225,400	$55.2M	0.03%	+146.6%
46	MARSHALL WACE, LLP#46 · 223,386 sh	223,386	$54.7M	0.04%	+58.2%
47	PFM Health Sciences#47 · 219,596 sh	219,596	$53.8M	4.61%	-16.9%
48	Tri Locum Partners#48 · 219,308 sh	219,308	$53.7M	6.60%	+253.1%
49	First Turn Management#49 · 218,415 sh	218,415	$53.5M	5.72%	+15.7%
50	Bank of New York Mellon#50 · 197,226 sh	197,226	$48.3M	<0.01%	-4.6%
51	Nuveen#51 · 190,080 sh	190,080	$46.5M	0.01%	-43.4%
52	HRT FINANCIAL#52 · 180,591 sh	180,591	$43.7M	0.11%	+1484.1%
53	FEDERATED HERMES#53 · 177,842 sh	177,842	$43.5M	0.06%	+63.8%
54	Woodline Partners#54 · 162,221 sh	162,221	$39.7M	0.12%	0.0%
55	JPMORGAN CHASE#55 · 162,065 sh	162,065	$39.5M	<0.01%	-40.0%
56	Sofinnova Ventures#56 · 160,429 sh	160,429	$39.3M	2.03%	-24.6%
57	Neuberger Berman Group#57 · 156,523 sh	156,523	$38.3M	0.03%	+157.6%
58	RAYMOND JAMES FINANCIAL#58 · 155,855 sh	155,855	$38.1M	0.01%	+5.5%
59	Squarepoint Ops#59 · 154,605 sh	154,605	$37.8M	0.04%	+35.5%
60	UBS Group AG#60 · 151,903 sh	151,903	$37.2M	<0.01%	-72.2%
61	WESTFIELD CAPITAL MANAGEMENT#61 · 145,145 sh	145,145	$35.5M	0.12%	New
62	VOYA INVESTMENT MANAGEMENT#62 · 142,051 sh	142,051	$34.8M	0.03%	-22.8%
63	CITIGROUP#63 · 136,858 sh	136,858	$33.5M	0.01%	-26.3%
64	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP#64 · 135,195 sh	135,195	$33.1M	0.01%	New
65	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#65 · 127,178 sh	127,178	$31.1M	<0.01%	+34.0%
66	MANUFACTURERS LIFE INSURANCE COMPANY, THE#66 · 118,999 sh	118,999	$29.1M	0.02%	+1.6%
67	PERCEPTIVE ADVISORS#67 · 118,450 sh	118,450	$29.0M	0.44%	-21.0%
68	ORBIMED ADVISORS#68 · 117,578 sh	117,578	$28.8M	0.53%	-45.0%
69	PUBLIC SECTOR PENSION INVESTMENT BOARD#69 · 116,000 sh	116,000	$28.4M	0.07%	New
70	AQR CAPITAL MANAGEMENT#70 · 114,025 sh	114,025	$27.9M	<0.01%	+9.6%
71	EMERALD ADVISERS#71 · 104,237 sh	104,237	$25.5M	0.60%	-3.1%
72	Nicholas Investment Partners#72 · 98,974 sh	98,974	$24.2M	1.36%	+21.5%
73	Connor, Clark & Lunn Investment Management Ltd.#73 · 97,698 sh	97,698	$23.9M	0.05%	-27.5%
74	ALGERT GLOBAL#74 · 95,335 sh	95,335	$23.3M	0.28%	-29.6%
75	ROYCE & ASSOCIATES#75 · 91,041 sh	91,041	$22.3M	0.18%	-3.2%
76	MetLife Investment Management#76 · 89,662 sh	89,662	$21.9M	0.10%	-41.3%
77	SUSQUEHANNA INTERNATIONAL GROUP, LLP#77 · 87,815 sh	87,815	$21.5M	<0.01%	+86.1%
78	DEUTSCHE BANK AG\#78 · 86,466 sh	86,466	$21.2M	<0.01%	-17.1%
79	Voleon Capital Management#79 · 84,433 sh	84,433	$20.7M	0.38%	-42.9%
80	Spears Abacus Advisors#80 · 84,154 sh	84,154	$20.6M	0.37%	0.0%
81	Trexquant Investment#81 · 83,679 sh	83,679	$20.5M	0.12%	+1309.9%
82	Man Group plc#82 · 82,526 sh	82,526	$20.2M	0.03%	-42.0%
83	Granite Investment Partners#83 · 80,124 sh	80,124	$19.6M	1.00%	-0.2%
84	Weiss Asset Management#84 · 80,000 sh	80,000	$19.6M	0.21%	New
85	Swiss National Bank#85 · 79,500 sh	79,500	$19.5M	0.01%	+15.1%
86	abrdn plc#86 · 78,236 sh	78,236	$19.1M	0.03%	-47.7%
87	SEI INVESTMENTS#87 · 76,462 sh	76,462	$18.7M	0.02%	+9.1%
88	BALYASNY ASSET MANAGEMENT L.P.#88 · 76,250 sh	76,250	$18.7M	0.02%	New
89	CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM#89 · 74,778 sh	74,778	$18.3M	0.01%	+47.0%
90	WCM INVESTMENT MANAGEMENT#90 · 75,713 sh	75,713	$18.3M	0.03%	-29.8%
91	LORD, ABBETT#91 · 73,978 sh	73,978	$18.1M	0.05%	New
92	Science & Technology Partners, L.P.#92 · 73,040 sh	73,040	$17.9M	3.01%	New
93	TimesSquare Capital Management#93 · 71,510 sh	71,510	$17.5M	0.26%	New
94	EMERALD MUTUAL FUND ADVISERS#94 · 67,195 sh	67,195	$16.4M	0.58%	+0.2%
95	US BANCORP \DE\#95 · 66,580 sh	66,580	$16.3M	0.02%	-49.3%
96	DnB Asset Management AS#96 · 65,199 sh	65,199	$16.0M	0.04%	-27.6%
97	Eagle Health Investments#97 · 65,051 sh	65,051	$15.9M	2.64%	New
98	Universal- Beteiligungs- und Servicegesellschaft mbH#98 · 63,551 sh	63,551	$15.6M	0.02%	-10.1%
99	Rhenman & Partners Asset Management AB#99 · 63,050 sh	63,050	$15.4M	1.46%	-1.2%
100	Atika Capital Management#100 · 63,000 sh	63,000	$15.4M	1.01%	New

Funds that sold out of AXSM in Q2 2026 (39)

Held AXSM at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held AXSM in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
Cormorant Asset Management50,000 sh	50,000	$8.5M
Blackstone24,500 sh	24,500	$4.1M
SCHRODER INVESTMENT MANAGEMENT GROUP23,830 sh	23,830	$3.8M
Empowered Funds20,997 sh	20,997	$3.5M
TFG Asset Management GP Ltd20,059 sh	20,059	$3.4M
MIRAE ASSET GLOBAL ETFS Ltd.19,452 sh	19,452	$3.3M
ExodusPoint Capital Management17,763 sh	17,763	$3.0M
Magnetar Financial16,009 sh	16,009	$2.7M
SummitTX Capital, L.P.15,304 sh	15,304	$2.6M
LANDSCAPE CAPITAL MANAGEMENT, L.L.C.14,129 sh	14,129	$2.4M
T. Rowe Price Investment Management13,643 sh	13,643	$2.3M
LAZARD ASSET MANAGEMENT13,163 sh	13,163	$2.2M
FRANKLIN STREET ADVISORS10,000 sh	10,000	$1.7M
BURNEY9,636 sh	9,636	$1.6M
Verdad Advisers5,971 sh	5,971	$1.0M
FARALLON CAPITAL MANAGEMENT4,000 sh	4,000	$676.1K
Campbell & Investment Adviser3,770 sh	3,770	$637.2K
Toroso Investments3,685 sh	3,685	$622.8K
Ameritas Investment Partners3,381 sh	3,381	$571.5K
SIG BROKERAGE2,298 sh	2,298	$388.4K
McAdam2,135 sh	2,135	$360.9K
Quantitative Investment Management2,040 sh	2,040	$344.0K
Freestone Grove Partners1,887 sh	1,887	$318.9K
Orion Porfolio Solutions1,536 sh	1,536	$259.6K
Centiva Capital1,288 sh	1,288	$217.7K
CFG Wealth Management Services470 sh	470	$79.4K
QUADRANT CAPITAL GROUP270 sh	270	$71.8K
Kemnay Advisory Services337 sh	337	$57.0K
Advisory Services Network325 sh	325	$54.9K
MAI Capital Management291 sh	291	$49.2K
GROUP ONE TRADING, L.P.214 sh	214	$36.2K
Opal Wealth Advisors167 sh	167	$28.2K
EASTERN BANK114 sh	114	$19.3K
Optiver Holding B.V.69 sh	69	$11.7K
Golden State Equity Partners67 sh	67	$11.3K
NATIONAL BANK OF CANADA37 sh	37	$6.2K
Steward Partners Investment Advisory35 sh	35	$5.9K
TWIN PEAKS WEALTH ADVISORS12 sh	12	$2.0K
Abound Wealth Management9 sh	9	$1.5K

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.