Apogee Therapeutics, Inc. (APGE) — Institutional Holders, Q2 2026
289 institutional investment managers reported a APGE position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $8.9B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
APGE in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- HBK INVESTMENTS L PNew · +2,850,000 sh+$378.3M
- GLAZER CAPITALNew · +1,641,042 sh+$217.8M
- Pentwater Capital ManagementNew · +1,425,000 sh+$189.1M
- BlackRockAdded · +1,421,381 sh+$188.7M
- MILLENNIUM MANAGEMENTAdded · +1,398,812 sh+$185.7M
Biggest sellers
- T. Rowe Price Investment ManagementTrimmed · -9,538,801 sh-$1.3B
- FMRTrimmed · -6,769,154 sh-$898.5M
- WELLINGTON MANAGEMENT GROUP LLPTrimmed · -3,811,377 sh-$505.9M
- RTW INVESTMENTSSold out · -2,782,097 sh-$369.3M
- Vestal Point CapitalSold out · -1,100,000 sh-$146.0M
APGE 13F holders ranked 1–100 of 289
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | VR Adviser#1 · 8,493,321 sh | 8,493,321 | $1.1B | 34.18% | 0.0% |
| 2 | BlackRock#2 · 5,507,032 sh | 5,507,032 | $730.9M | 0.01% | +34.8% |
| 3 | HBK INVESTMENTS L P#3 · 2,850,000 sh | 2,850,000 | $378.3M | 3.70% | New |
| 4 | VANGUARD CAPITAL MANAGEMENT#4 · 2,572,119 sh | 2,572,119 | $341.4M | <0.01% | +2.8% |
| 5 | FMR#5 · 2,493,137 sh | 2,493,137 | $330.9M | 0.01% | -73.1% |
| 6 | STATE STREET#6 · 2,297,743 sh | 2,297,743 | $305.0M | <0.01% | +6.2% |
| 7 | DRIEHAUS CAPITAL MANAGEMENT#7 · 1,740,101 sh | 1,740,101 | $231.0M | 1.34% | -9.4% |
| 8 | GOLDMAN SACHS GROUP#8 · 1,693,341 sh | 1,693,341 | $224.8M | 0.02% | +159.5% |
| 9 | BALYASNY ASSET MANAGEMENT L.P.#9 · 1,665,102 sh | 1,665,102 | $221.0M | 0.28% | +279.6% |
| 10 | GLAZER CAPITAL#10 · 1,641,042 sh | 1,641,042 | $217.8M | 5.36% | New |
| 11 | Paradigm Biocapital Advisors#11 · 1,576,385 sh | 1,576,385 | $209.2M | 3.92% | +16.9% |
| 12 | VANGUARD PORTFOLIO MANAGEMENT#12 · 1,528,750 sh | 1,528,750 | $202.9M | <0.01% | +285.7% |
| 13 | MILLENNIUM MANAGEMENT#13 · 1,491,404 sh | 1,491,404 | $198.0M | 0.07% | +1510.7% |
| 14 | Pentwater Capital Management#14 · 1,425,000 sh | 1,425,000 | $189.1M | 1.16% | New |
| 15 | MORGAN STANLEY#15 · 1,421,681 sh | 1,421,681 | $188.7M | 0.01% | +138.9% |
| 16 | GEODE CAPITAL MANAGEMENT#16 · 1,314,868 sh | 1,314,868 | $174.6M | <0.01% | +8.0% |
| 17 | PERCEPTIVE ADVISORS#17 · 1,308,113 sh | 1,308,113 | $173.6M | 2.61% | -15.1% |
| 18 | Jupiter Topco#18 · 1,193,626 sh | 1,193,626 | $158.4M | 0.06% | — |
| 19 | BANK OF AMERICA#19 · 1,126,139 sh | 1,126,139 | $149.5M | <0.01% | +25.0% |
| 20 | Affinity Asset Advisors#20 · 987,000 sh | 987,000 | $131.0M | 5.92% | -23.2% |
| 21 | MERCER GLOBAL ADVISORS#21 · 941,283 sh | 941,283 | $124.9M | 0.15% | +13.2% |
| 22 | First Light Asset Management#22 · 930,289 sh | 930,289 | $123.5M | 7.50% | +61.3% |
| 23 | T. Rowe Price Investment Management#23 · 762,183 sh | 762,183 | $101.2M | 0.07% | -92.6% |
| 24 | Kryger Capital#24 · 742,555 sh | 742,555 | $98.6M | 5.62% | New |
| 25 | Qube Research & Technologies Ltd#25 · 659,678 sh | 659,678 | $87.6M | 0.08% | New |
| 26 | First Capital Management L.P.#26 · 625,182 sh | 625,182 | $83.0M | 4.83% | New |
| 27 | Remedium Capital Partners#27 · 586,691 sh | 586,691 | $77.9M | 17.24% | +0.5% |
| 28 | SOROS FUND MANAGEMENT#28 · 564,500 sh | 564,500 | $74.9M | 0.92% | New |
| 29 | WELLINGTON MANAGEMENT GROUP LLP#29 · 564,326 sh | 564,326 | $74.9M | 0.01% | -87.1% |
| 30 | ALLIANCEBERNSTEIN L.P.#30 · 775,058 sh | 775,058 | $65.2M | 0.02% | -21.7% |
| 31 | Woodline Partners#31 · 464,622 sh | 464,622 | $61.7M | 0.19% | +77.9% |
| 32 | WHITEBOX ADVISORS#32 · 450,001 sh | 450,001 | $59.7M | 0.78% | New |
| 33 | NORTHERN#33 · 445,154 sh | 445,154 | $59.1M | <0.01% | +13.9% |
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT#34 · 443,658 sh | 443,658 | $58.9M | <0.01% | +5.5% |
| 35 | AQR Arbitrage#35 · 429,900 sh | 429,900 | $57.1M | 0.81% | New |
| 36 | Magnetar Financial#36 · 399,123 sh | 399,123 | $53.0M | 0.48% | New |
| 37 | Man Group plc#37 · 397,000 sh | 397,000 | $52.7M | 0.08% | +849.4% |
| 38 | VANGUARD FIDUCIARY#38 · 393,180 sh | 393,180 | $52.2M | 0.01% | +6.6% |
| 39 | Opaleye Management#39 · 390,000 sh | 390,000 | $51.8M | 4.69% | 0.0% |
| 40 | TIG Advisors#40 · 364,250 sh | 364,250 | $48.3M | 2.14% | New |
| 41 | FRANKLIN RESOURCES#41 · 363,379 sh | 363,379 | $48.2M | 0.01% | -10.4% |
| 42 | JPMORGAN CHASE#42 · 359,250 sh | 359,250 | $47.9M | <0.01% | -67.6% |
| 43 | Cinctive Capital Management#43 · 350,165 sh | 350,165 | $46.5M | 1.71% | New |
| 44 | LOOMIS SAYLES & L P#44 · 338,664 sh | 338,664 | $45.0M | 0.06% | -6.6% |
| 45 | Polar Asset Management Partners#45 · 322,467 sh | 322,467 | $42.8M | 0.70% | New |
| 46 | FRONTIER CAPITAL MANAGEMENT#46 · 303,739 sh | 303,739 | $40.3M | 0.38% | -71.5% |
| 47 | NEXPOINT ASSET MANAGEMENT, L.P.#47 · 299,940 sh | 299,940 | $39.8M | 2.66% | New |
| 48 | Fairmount Funds Management#48 · 298,647 sh | 298,647 | $39.6M | 2.62% | 0.0% |
| 49 | Squarepoint Ops#49 · 290,713 sh | 290,713 | $38.6M | 0.04% | +658.1% |
| 50 | CITIGROUP#50 · 289,464 sh | 289,464 | $38.4M | 0.01% | +1969.4% |
| 51 | Slotnik Capital#51 · 260,740 sh | 260,740 | $34.6M | 8.94% | New |
| 52 | EVENTIDE ASSET MANAGEMENT#52 · 260,000 sh | 260,000 | $34.5M | 0.46% | -53.4% |
| 53 | ADAGE CAPITAL PARTNERS GP, L.L.C.#53 · 250,000 sh | 250,000 | $33.2M | 0.05% | 0.0% |
| 54 | D. E. Shaw#54 · 246,086 sh | 246,086 | $32.7M | 0.02% | +318.3% |
| 55 | PRICE T ROWE ASSOCIATES#55 · 237,210 sh | 237,210 | $31.5M | <0.01% | -79.2% |
| 56 | BNP PARIBAS FINANCIAL MARKETS#56 · 210,212 sh | 210,212 | $27.9M | <0.01% | -4.5% |
| 57 | Absolute Gestao de Investimentos Ltda.#57 · 205,000 sh | 205,000 | $27.2M | 2.74% | New |
| 58 | UBS Group AG#58 · 201,831 sh | 201,831 | $26.8M | <0.01% | -82.4% |
| 59 | MUFG Securities EMEA plc#59 · 180,500 sh | 180,500 | $24.0M | 0.25% | New |
| 60 | Allianz Asset Management GmbH#60 · 179,500 sh | 179,500 | $23.7M | 0.02% | +7080.0% |
| 61 | PICTON MAHONEY ASSET MANAGEMENT#61 · 165,000 sh | 165,000 | $21.9M | 0.16% | New |
| 62 | Verition Fund Management#62 · 159,256 sh | 159,256 | $21.1M | 0.03% | New |
| 63 | HIGHBRIDGE CAPITAL MANAGEMENT#63 · 155,857 sh | 155,857 | $20.7M | 0.50% | New |
| 64 | Sagefield Capital#64 · 155,135 sh | 155,135 | $20.6M | 1.53% | New |
| 65 | Bank of New York Mellon#65 · 152,815 sh | 152,815 | $20.3M | <0.01% | +20.6% |
| 66 | RENAISSANCE TECHNOLOGIES#66 · 146,800 sh | 146,800 | $19.5M | 0.03% | New |
| 67 | First Turn Management#67 · 138,822 sh | 138,822 | $18.4M | 1.97% | -73.0% |
| 68 | Grantham, Mayo, Van Otterloo#68 · 137,395 sh | 137,395 | $18.2M | 0.04% | New |
| 69 | Nuveen#69 · 131,634 sh | 131,634 | $17.5M | <0.01% | +2.7% |
| 70 | GABELLI FUNDS#70 · 127,281 sh | 127,281 | $16.9M | 0.11% | New |
| 71 | Universal- Beteiligungs- und Servicegesellschaft mbH#71 · 121,258 sh | 121,258 | $16.1M | 0.02% | -5.3% |
| 72 | Twin Securities#72 · 120,000 sh | 120,000 | $15.9M | 7.13% | New |
| 73 | CAPSTONE INVESTMENT ADVISORS#73 · 120,000 sh | 120,000 | $15.9M | 0.01% | New |
| 74 | Melqart Asset Management (UK) Ltd#74 · 117,249 sh | 117,249 | $15.6M | 1.48% | New |
| 75 | Maven Securities LTD#75 · 115,018 sh | 115,018 | $15.3M | 0.30% | +360.1% |
| 76 | SEVEN GRAND MANAGERS#76 · 100,000 sh | 100,000 | $13.3M | 0.53% | 0.0% |
| 77 | DEUTSCHE BANK AG\#77 · 98,979 sh | 98,979 | $13.1M | <0.01% | +8.3% |
| 78 | WATER ISLAND CAPITAL#78 · 94,900 sh | 94,900 | $12.6M | 1.17% | New |
| 79 | TWO SIGMA INVESTMENTS#79 · 94,759 sh | 94,759 | $12.6M | <0.01% | -66.3% |
| 80 | VICTORY CAPITAL MANAGEMENT#80 · 87,953 sh | 87,953 | $11.7M | <0.01% | -7.6% |
| 81 | Handelsbanken Fonder AB#81 · 86,300 sh | 86,300 | $11.5M | 0.03% | +309.0% |
| 82 | Groupe la Francaise#82 · 84,072 sh | 84,072 | $11.2M | 0.07% | New |
| 83 | GABELLI & INVESTMENT ADVISERS#83 · 81,645 sh | 81,645 | $10.8M | 1.58% | New |
| 84 | GARDNER LEWIS ASSET MANAGEMENT L P#84 · 80,000 sh | 80,000 | $10.6M | 2.37% | New |
| 85 | Candriam S.C.A.#85 · 79,684 sh | 79,684 | $10.6M | 0.05% | -64.4% |
| 86 | HARVEST MANAGEMENT#86 · 79,000 sh | 79,000 | $10.5M | 4.12% | New |
| 87 | MARSHALL WACE, LLP#87 · 77,475 sh | 77,475 | $10.3M | <0.01% | -3.4% |
| 88 | Swiss National Bank#88 · 76,700 sh | 76,700 | $10.2M | <0.01% | +1.5% |
| 89 | PRUDENTIAL FINANCIAL#89 · 76,620 sh | 76,620 | $10.2M | 0.01% | +19.9% |
| 90 | WCM INVESTMENT MANAGEMENT#90 · 75,974 sh | 75,974 | $10.1M | 0.02% | -0.1% |
| 91 | Alberta Investment Management#91 · 75,000 sh | 75,000 | $10.0M | 0.06% | New |
| 92 | Chicago Capital Management#92 · 97,100 sh | 97,100 | $9.8M | — | New |
| 93 | Westchester Capital Management#93 · 72,962 sh | 72,962 | $9.7M | 0.47% | New |
| 94 | Boxer Capital Management#94 · 70,000 sh | 70,000 | $9.3M | 0.70% | 0.0% |
| 95 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#95 · 66,433 sh | 66,433 | $8.8M | <0.01% | +17.9% |
| 96 | KENNEDY CAPITAL MANAGEMENT#96 · 63,981 sh | 63,981 | $8.5M | 0.15% | -47.8% |
| 97 | CREDIT INDUSTRIEL ET COMMERCIAL#97 · 63,424 sh | 63,424 | $8.4M | 0.54% | New |
| 98 | ALPS ADVISORS#98 · 62,523 sh | 62,523 | $8.3M | 0.04% | +37.2% |
| 99 | Beryl Capital Management#99 · 58,676 sh | 58,676 | $7.8M | 7.04% | New |
| 100 | PRELUDE CAPITAL MANAGEMENT#100 · 58,590 sh | 58,590 | $7.8M | 0.57% | +876.5% |
Funds that sold out of APGE in Q2 2026 (47)
Held APGE at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| RTW INVESTMENTS2,782,097 sh | 2,782,097 | $234.2M |
| Vestal Point Capital1,100,000 sh | 1,100,000 | $92.6M |
| Polar Capital Plc539,177 sh | 539,177 | $45.4M |
| BRAIDWELL478,667 sh | 478,667 | $40.3M |
| Novo A/S450,000 sh | 450,000 | $37.9M |
| GREAT POINT PARTNERS374,000 sh | 374,000 | $31.5M |
| Capital World Investors348,674 sh | 348,674 | $29.3M |
| Deep Track Capital285,000 sh | 285,000 | $24.0M |
| abrdn plc143,379 sh | 143,379 | $12.1M |
| Nicholas Investment Partners130,992 sh | 130,992 | $11.0M |
| ArrowMark Colorado109,410 sh | 109,410 | $9.2M |
| NOMURA88,561 sh | 88,561 | $7.5M |
| Parkman Healthcare Partners77,686 sh | 77,686 | $6.5M |
| Alyeska Investment Group, L.P.75,000 sh | 75,000 | $6.3M |
| Rhenman & Partners Asset Management AB75,000 sh | 75,000 | $6.3M |
| Holocene Advisors57,473 sh | 57,473 | $4.8M |
| Lisanti Capital Growth52,260 sh | 52,260 | $4.4M |
| HighVista Strategies35,761 sh | 35,761 | $3.0M |
| Legato Capital Management29,968 sh | 29,968 | $2.5M |
| MOODY ALDRICH PARTNERS29,080 sh | 29,080 | $2.4M |
| BANQUE PICTET & CIE SA19,960 sh | 19,960 | $1.7M |
| Shay Capital16,500 sh | 16,500 | $1.4M |
| BAMCO15,000 sh | 15,000 | $1.3M |
| TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY12,844 sh | 12,844 | $1.1M |
| Birchview Capital9,000 sh | 9,000 | $757.5K |
| DnB Asset Management AS7,991 sh | 7,991 | $672.6K |
| Global Endowment Management7,797 sh | 7,797 | $656.0K |
| B Group7,500 sh | 7,500 | $631.3K |
| FORA Capital7,099 sh | 7,099 | $598.2K |
| DARK FOREST CAPITAL MANAGEMENT6,476 sh | 6,476 | $545.1K |
| Allspring Global Investments6,052 sh | 6,052 | $509.8K |
| Headlands Technologies5,887 sh | 5,887 | $495.5K |
| Artia Global Partners5,886 sh | 5,886 | $495.4K |
| Hudson Bay Capital Management5,720 sh | 5,720 | $481.5K |
| Jain Global4,893 sh | 4,893 | $411.8K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd.4,007 sh | 4,007 | $337.3K |
| OMERS ADMINISTRATION3,400 sh | 3,400 | $286.2K |
| Twin Tree Management3,295 sh | 3,295 | $277.3K |
| STIFEL FINANCIAL2,814 sh | 2,814 | $236.9K |
| PSP Research2,500 sh | 2,500 | $210.4K |
| Seven Fleet Capital Management1,969 sh | 1,969 | $165.7K |
| QUADRANT CAPITAL GROUP188 sh | 188 | $56.9K |
| Kemnay Advisory Services430 sh | 430 | $36.2K |
| Sound Income Strategies51 sh | 51 | $4.3K |
| Aster Capital Management (DIFC) Ltd99 sh | 99 | $3.7K |
| MAI Capital Management6 sh | 6 | $506.00 |
| Root Financial Partners4 sh | 4 | $337.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.