ANAPTYSBIO, INC (ANAB) — Institutional Holders, Q2 2026

214 institutional investment managers reported a ANAB position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $2.1B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← ANAB stock profile

ANAB in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

Trimmed

Sold out

Biggest buyers

Woodline PartnersAdded · +372,758 sh+$25.2M
MILLENNIUM MANAGEMENTAdded · +331,744 sh+$22.4M
STATE STREETAdded · +293,749 sh+$19.8M
APIS CAPITAL ADVISORSAdded · +259,000 sh+$17.5M
FIRST ADVISORSNew · +258,989 sh+$17.5M

Biggest sellers

MORGAN STANLEYTrimmed · -736,814 sh-$49.7M
Synergy Financial ManagementSold out · -317,106 sh-$21.4M
FMRTrimmed · -232,193 sh-$15.7M
TWO SIGMA INVESTMENTSTrimmed · -202,088 sh-$13.6M
Affinity Asset AdvisorsTrimmed · -113,891 sh-$7.7M

ANAB 13F holders ranked 1–100 of 214

Institutional investors reporting a position in ANAPTYSBIO, INC on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	EcoR1 Capital#1 · 7,880,094 sh	7,880,094	$531.9M	25.86%	0.0%
2	BlackRock#2 · 1,844,049 sh	1,844,049	$124.5M	<0.01%	+9.7%
3	TANG CAPITAL MANAGEMENT#3 · 1,330,879 sh	1,330,879	$89.8M	4.08%	0.0%
4	STATE STREET#4 · 1,286,194 sh	1,286,194	$86.8M	<0.01%	+29.6%
5	VANGUARD CAPITAL MANAGEMENT#5 · 906,233 sh	906,233	$61.2M	<0.01%	+6.2%
6	Affinity Asset Advisors#6 · 826,109 sh	826,109	$55.8M	2.52%	-12.1%
7	Sanofi#7 · 821,917 sh	821,917	$55.5M	10.39%	0.0%
8	MILLENNIUM MANAGEMENT#8 · 807,316 sh	807,316	$54.5M	0.02%	+69.8%
9	Woodline Partners#9 · 717,014 sh	717,014	$48.4M	0.15%	+108.3%
10	683 Capital Management#10 · 660,000 sh	660,000	$44.6M	2.19%	+5.6%
11	GEODE CAPITAL MANAGEMENT#11 · 637,873 sh	637,873	$43.1M	<0.01%	+22.6%
12	Palo Alto Investors#12 · 603,489 sh	603,489	$40.7M	5.63%	-5.4%
13	GOLDMAN SACHS GROUP#13 · 584,070 sh	584,070	$39.4M	<0.01%	+75.5%
14	First Light Asset Management#14 · 582,004 sh	582,004	$39.3M	2.39%	+2.9%
15	D. E. Shaw#15 · 539,666 sh	539,666	$36.4M	0.02%	-6.8%
16	VANGUARD PORTFOLIO MANAGEMENT#16 · 527,858 sh	527,858	$35.6M	<0.01%	+1.5%
17	APIS CAPITAL ADVISORS#17 · 497,000 sh	497,000	$33.5M	3.27%	+108.8%
18	Sofinnova Ventures#18 · 493,536 sh	493,536	$33.3M	1.72%	+98.8%
19	ARROWSTREET CAPITAL, LIMITED PARTNERSHIP#19 · 488,651 sh	488,651	$33.0M	0.01%	-0.7%
20	Nuveen#20 · 420,664 sh	420,664	$28.4M	<0.01%	+33.1%
21	BANK OF AMERICA#21 · 417,812 sh	417,812	$28.2M	<0.01%	-16.6%
22	CITADEL ADVISORS#22 · 394,373 sh	394,373	$26.6M	<0.01%	+68.9%
23	FEDERATED HERMES#23 · 391,667 sh	391,667	$26.4M	0.04%	+7.6%
24	Squarepoint Ops#24 · 324,446 sh	324,446	$21.9M	0.02%	+21.2%
25	TWO SIGMA INVESTMENTS#25 · 262,995 sh	262,995	$17.8M	0.01%	-43.5%
26	FIRST ADVISORS#26 · 258,989 sh	258,989	$17.5M	0.01%	New
27	MORGAN STANLEY#27 · 257,091 sh	257,091	$17.4M	<0.01%	-74.1%
28	Coppell Advisory Solutions#28 · 3,638 sh	3,638	$16.6M	1.34%	New
29	FMR#29 · 240,511 sh	240,511	$16.2M	<0.01%	-49.1%
30	Qube Research & Technologies Ltd#30 · 228,777 sh	228,777	$15.4M	0.01%	-10.2%
31	HSBC PLC#31 · 216,949 sh	216,949	$14.9M	<0.01%	+72.6%
32	Empowered Funds#32 · 206,010 sh	206,010	$13.9M	0.07%	New
33	NORTHERN#33 · 202,767 sh	202,767	$13.7M	<0.01%	+10.5%
34	CHARLES SCHWAB INVESTMENT MANAGEMENT#34 · 202,305 sh	202,305	$13.7M	<0.01%	+5.0%
35	Invesco Ltd.#35 · 202,056 sh	202,056	$13.6M	<0.01%	+66.8%
36	DIMENSIONAL FUND ADVISORS#36 · 185,444 sh	185,444	$12.5M	<0.01%	New
37	Greenhaven Road Investment Management, L.P.#37 · 171,059 sh	171,059	$11.5M	7.50%	New
38	VICTORY CAPITAL MANAGEMENT#38 · 169,227 sh	169,227	$11.4M	<0.01%	+56.4%
39	MACKENZIE FINANCIAL#39 · 150,979 sh	150,979	$10.2M	0.01%	+347.7%
40	UBS Group AG#40 · 146,832 sh	146,832	$9.9M	<0.01%	+84.3%
41	VANGUARD FIDUCIARY#41 · 146,724 sh	146,724	$9.9M	<0.01%	+8.6%
42	Connor, Clark & Lunn Investment Management Ltd.#42 · 141,026 sh	141,026	$9.5M	0.02%	-11.1%
43	Ensign Peak Advisors#43 · 107,096 sh	107,096	$7.2M	0.01%	-14.8%
44	FRANKLIN RESOURCES#44 · 106,949 sh	106,949	$7.2M	<0.01%	+62.5%
45	CITIGROUP#45 · 99,114 sh	99,114	$6.7M	<0.01%	+35.0%
46	NOMURA ASSET MANAGEMENT INTERNATIONAL#46 · 93,732 sh	93,732	$6.3M	<0.01%	0.0%
47	PRUDENTIAL FINANCIAL#47 · 85,932 sh	85,932	$5.8M	<0.01%	+34.2%
48	DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt#48 · 83,942 sh	83,942	$5.7M	<0.01%	New
49	JPMORGAN CHASE#49 · 80,236 sh	80,236	$5.3M	<0.01%	+589.0%
50	Granahan Investment Management#50 · 75,962 sh	75,962	$5.1M	0.18%	+14.8%
51	Irenic Capital Management#51 · 70,447 sh	70,447	$4.8M	0.23%	New
52	Eversept Partners#52 · 69,983 sh	69,983	$4.7M	0.25%	+158.3%
53	SG Americas Securities#53 · 66,730 sh	66,730	$4.5M	<0.01%	+168.5%
54	JACOBS LEVY EQUITY MANAGEMENT#54 · 62,336 sh	62,336	$4.2M	0.02%	+117.8%
55	STATE OF WISCONSIN INVESTMENT BOARD#55 · 61,753 sh	61,753	$4.2M	<0.01%	+123.6%
56	RENAISSANCE TECHNOLOGIES#56 · 58,300 sh	58,300	$3.9M	<0.01%	-35.9%
57	VOLORIDGE INVESTMENT MANAGEMENT#57 · 57,555 sh	57,555	$3.9M	0.02%	-27.1%
58	Bank of New York Mellon#58 · 56,401 sh	56,401	$3.8M	<0.01%	+10.3%
59	DEUTSCHE BANK AG\#59 · 46,884 sh	46,884	$3.2M	<0.01%	-9.9%
60	AQR CAPITAL MANAGEMENT#60 · 46,323 sh	46,323	$3.1M	<0.01%	+42.7%
61	MARSHALL WACE, LLP#61 · 43,822 sh	43,822	$3.0M	<0.01%	-35.6%
62	Bleakley Financial Group#62 · 42,761 sh	42,761	$2.9M	0.04%	-0.8%
63	WELLINGTON MANAGEMENT GROUP LLP#63 · 41,796 sh	41,796	$2.8M	<0.01%	-10.8%
64	WELLS FARGO & COMPANY#64 · 41,707 sh	41,707	$2.8M	<0.01%	+25.7%
65	HighMark Wealth Management#65 · 39,716 sh	39,716	$2.7M	0.90%	-57.8%
66	CAPITAL FUND MANAGEMENT S.A.#66 · 39,142 sh	39,142	$2.6M	0.01%	New
67	Trexquant Investment#67 · 35,404 sh	35,404	$2.4M	0.01%	-58.4%
68	VIRGINIA RETIREMENT SYSTEMS ET Al#68 · 34,500 sh	34,500	$2.3M	<0.01%	+115.0%
69	Atom Investors#69 · 33,917 sh	33,917	$2.3M	0.20%	New
70	PRICE T ROWE ASSOCIATES#70 · 32,374 sh	32,374	$2.2M	<0.01%	+9.0%
71	Swiss National Bank#71 · 31,700 sh	31,700	$2.1M	<0.01%	+14.9%
72	Voleon Capital Management#72 · 31,425 sh	31,425	$2.1M	0.04%	New
73	Toroso Investments#73 · 31,270 sh	31,270	$2.1M	<0.01%	-14.0%
74	TEMA ETFS#74 · 31,270 sh	31,270	$2.1M	—	+0.6%
75	MOODY ALDRICH PARTNERS#75 · 30,926 sh	30,926	$2.1M	0.38%	-21.6%
76	Aquatic Capital Management#76 · 30,813 sh	30,813	$2.1M	0.07%	New
77	SummitTX Capital, L.P.#77 · 28,779 sh	28,779	$1.9M	0.05%	New
78	ALLIANCEBERNSTEIN L.P.#78 · 32,820 sh	32,820	$1.8M	<0.01%	+4.8%
79	RHUMBLINE ADVISERS#79 · 26,346 sh	26,346	$1.8M	<0.01%	+10.5%
80	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#80 · 23,310 sh	23,310	$1.6M	<0.01%	-24.1%
81	BURNEY#81 · 22,557 sh	22,557	$1.5M	—	New
82	Rafferty Asset Management#82 · 21,864 sh	21,864	$1.5M	<0.01%	-19.8%
83	XTX Topco Ltd#83 · 21,411 sh	21,411	$1.4M	0.02%	-57.6%
84	HUSSMAN STRATEGIC ADVISORS#84 · 21,000 sh	21,000	$1.4M	0.33%	0.0%
85	TUDOR INVESTMENT ET AL#85 · 20,019 sh	20,019	$1.4M	<0.01%	+303.4%
86	CREDIT AGRICOLE S A#86 · 20,000 sh	20,000	$1.4M	<0.01%	0.0%
87	MARTINGALE ASSET MANAGEMENT L P#87 · 19,942 sh	19,942	$1.3M	0.03%	-29.1%
88	Creative Planning#88 · 18,773 sh	18,773	$1.3M	<0.01%	+11.5%
89	Y-Intercept (Hong Kong) Ltd#89 · 18,468 sh	18,468	$1.2M	—	-18.6%
90	LOS ANGELES CAPITAL MANAGEMENT#90 · 17,536 sh	17,536	$1.2M	<0.01%	+12.0%
91	Diametric Capital#91 · 16,868 sh	16,868	$1.1M	0.12%	New
92	CANADA PENSION PLAN INVESTMENT BOARD#92 · 16,500 sh	16,500	$1.1M	<0.01%	+10.7%
93	Legal & General Group Plc#93 · 16,415 sh	16,415	$1.1M	<0.01%	+18.7%
94	Russell Investments Group, Ltd.#94 · 16,301 sh	16,301	$1.1M	<0.01%	+22.7%
95	MASSACHUSETTS FINANCIAL SERVICES#95 · 15,870 sh	15,870	$1.1M	<0.01%	New
96	Cresset Asset Management#96 · 14,412 sh	14,412	$972.8K	<0.01%	+3.9%
97	Vanguard Global Advisers#97 · 13,919 sh	13,919	$939.5K	<0.01%	+18.4%
98	Zurcher Kantonalbank (Zurich Cantonalbank)#98 · 13,405 sh	13,405	$904.8K	<0.01%	+39.6%
99	Brevan Howard Capital Management#99 · 13,329 sh	13,329	$899.7K	<0.01%	+20.9%
100	SEI INVESTMENTS#100 · 13,161 sh	13,161	$888.4K	<0.01%	+71.9%

Funds that sold out of ANAB in Q2 2026 (37)

Held ANAB at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held ANAB in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
Synergy Financial Management317,106 sh	317,106	$17.6M
JANE STREET GROUP86,038 sh	86,038	$4.8M
Fisher Asset Management56,596 sh	56,596	$3.1M
Point72 Asset Management, L.P.55,303 sh	55,303	$3.1M
Penserra Capital Management43,430 sh	43,430	$2.4M
HRT FINANCIAL40,504 sh	40,504	$2.2M
Virtu Financial33,323 sh	33,323	$1.8M
Engineers Gate Manager27,815 sh	27,815	$1.5M
SUSQUEHANNA INTERNATIONAL GROUP, LLP26,577 sh	26,577	$1.5M
Headlands Technologies24,558 sh	24,558	$1.4M
J. Goldman21,205 sh	21,205	$1.2M
Walleye Capital18,425 sh	18,425	$1.0M
PDT Partners17,595 sh	17,595	$975.8K
TWINBEECH CAPITAL14,518 sh	14,518	$805.2K
Brookwood Investment Group13,362 sh	13,362	$741.1K
OXFORD ASSET MANAGEMENT LLP12,676 sh	12,676	$703.0K
Ground Swell Capital7,610 sh	7,610	$422.1K
ExodusPoint Capital Management7,260 sh	7,260	$402.6K
Soleus Capital Management, L.P.6,000 sh	6,000	$332.8K
Integrated Quantitative Investments5,606 sh	5,606	$310.9K
Bayforest Capital Ltd5,244 sh	5,244	$290.8K
BALYASNY ASSET MANAGEMENT L.P.4,905 sh	4,905	$272.0K
AXQ CAPITAL4,715 sh	4,715	$261.5K
Dynamic Technology Lab Private Ltd4,360 sh	4,360	$241.8K
Jump Financial3,900 sh	3,900	$216.3K
Aster Capital Management (DIFC) Ltd5,218 sh	5,218	$97.0K
QUADRANT CAPITAL GROUP354 sh	354	$58.8K
SBI Securities , Ltd.788 sh	788	$43.7K
NATIXIS333 sh	333	$18.5K
MEEDER ASSET MANAGEMENT240 sh	240	$13.3K
Wall Street Financial Group75 sh	75	$4.2K
Root Financial Partners16 sh	16	$887.00
MAI Capital Management11 sh	11	$611.00
Fortitude Family Office8 sh	8	$444.00
TWIN PEAKS WEALTH ADVISORS5 sh	5	$277.00
Advisory Services Network3 sh	3	$166.00
Keating Financial Advisory Services1 sh	1	$55.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.