How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to SR ONE

13F Portfolio OverlapQ2 2026SR ONE portfolio →

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Most similar hedge funds by 13F overlap

SR ONE CAPITAL MANAGEMENT, LP is an institutional investor managing $1.0B across 15 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to SR ONE are Catalio, Pivotal bioVenture Partners Investment Advisor, NEA Company, with shared positions in $AVLN, $MLYS, $ODTX, $MANE, $RARE, $ZBIO. The full ranking of 16 similar funds is below.

#1Catalio Capital Management, LPActive

Notable overlap · 5 shared positions

$AVLN $MLYS $ODTX $MANE $RARE

$532M

39 positions

#2Pivotal bioVenture Partners Investment Advisor LLCActive

Notable overlap · 3 shared positions

$AVLN $ZBIO $OCS

$308M

13 positions

#3NEA Management Company, LLCSmart money

Notable overlap · 4 shared positions

$ZBIO $CRSP $ORIC $NKTX

$1.6B

26 positions

#4Samsara BioCapital, LLCSmart money

Notable overlap · 3 shared positions

$ALMS $MLYS $NKTX

$1.2B

24 positions

#5EcoR1 Capital, LLCSmart money

Notable overlap · 4 shared positions

$CRSP $ORIC $ZBIO $ODTX

$2.1B

33 positions

#6Nextech Invest, Ltd.Smart money

Notable overlap · 3 shared positions

$ALMS $ORIC $ENGN

$2.1B

15 positions

#7SPHERA FUNDS MANAGEMENT LTD.Active

Some overlap · 4 shared positions

$MLYS $ORIC $ZBIO $RARE

$767M

105 positions

#8SILVERARC CAPITAL MANAGEMENT, LLCActive

Some overlap · 4 shared positions

$ORIC $ZBIO $MANE $AVLN

$962M

73 positions

#9MPM BioImpact LLCActive

Some overlap · 3 shared positions

$ALMS $ORIC $RARE

$1.6B

37 positions

#10Vivo Capital, LLCActive

Some overlap · 3 shared positions

$DSGN $ORIC $ODTX

$1.1B

47 positions

#11Logos Global Management LPActive

Some overlap · 4 shared positions

$DSGN $MLYS $MANE $CRSP

$2.3B

68 positions

#12Ishara Investments LPActive

Some overlap · 4 shared positions

$MLYS $ORIC $SPRY $RARE

$136M

41 positions

#13Omega Fund Management, LLCActive

Some overlap · 3 shared positions

$ALMS $ENGN $ODTX

$186M

10 positions

#14ORBIMED ADVISORS LLCActive

Some overlap · 3 shared positions

$SPRY $MLYS $ODTX

$5.4B

129 positions

#15Sofinnova Ventures IncActive

Slight overlap · 3 shared positions

$MANE $DSGN $RARE

$1.9B

57 positions

#16Elmind Capital, LPActive

Slight overlap · 3 shared positions

$ALMS $DSGN $ENGN

$398M

35 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.