What hedge funds are most similar to 5AM Venture Management, LLC?

The funds with the most similar 13F portfolios to 5AM Venture Management, LLC are Commodore, Velan Investment, Novo A/S, based on overlapping conviction holdings in the latest SEC filings.

How is hedge fund similarity measured?

Similarity is computed from each fund's top conviction holdings in their latest 13F filing. Funds are scored by the overlap of distinctive shared positions (the mega-caps that nearly every fund owns are excluded), so the ranking reflects genuinely shared strategy rather than common index exposure.

Hedge Funds Similar to 5AM Venture

13F Portfolio OverlapQ2 20265AM Venture portfolio →

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Most similar hedge funds by 13F overlap

5AM Venture Management, LLC is an institutional investor managing $288M across 16 U.S. equity positions as of Q2 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to 5AM Venture are Commodore, Velan Investment, Novo A/S, with shared positions in $EYPT, $TYRA, $CLDX, $PHVS, $MPLT, $TARA. The full ranking of 17 similar funds is below.

#1Commodore Capital LPActive

Notable overlap · 4 shared positions

$EYPT $TYRA $CLDX $PHVS

$1.7B

33 positions

#2Velan Capital Investment Management LPActive

Notable overlap · 4 shared positions

$MPLT $TARA $ARTV $TECX

$164M

51 positions

#3Novo Holdings A/SActive

Notable overlap · 3 shared positions

$MPLT $PHVS $CLDX

$1.7B

25 positions

#4Elmind Capital, LPActive

Notable overlap · 3 shared positions

$CLDX $PHVS $TYRA

$398M

35 positions

#5StemPoint Capital LPPassive

Notable overlap · 5 shared positions

$TYRA $BHVN $SRZN $CLDX $EYPT

$581M

84 positions

#6SUPERSTRING CAPITAL MANAGEMENT LPActive

Notable overlap · 3 shared positions

$CLDX $MPLT $TARA

$158M

32 positions

#7Kalehua Capital Management LLCActive

Notable overlap · 3 shared positions

$PHVS $SRZN $TYRA

$140M

23 positions

#8Cormorant Asset Management, LPActive

Notable overlap · 3 shared positions

$EYPT $BHVN $PHVS

$2.0B

50 positions

#9Propel Bio Management, LLCActive

Notable overlap · 4 shared positions

$ARTV $CLDX $EYPT $SLN

$191M

29 positions

#10Blue Owl Capital Holdings LPActive

Some overlap · 3 shared positions

$MPLT $EYPT $ARTV

$665M

76 positions

#11TCG Crossover Management, LLCActive

Some overlap · 6 shared positions

$TYRA $TECX $SRZN $PHVS $SLN $BHVN

$4.2B

54 positions

#12Sio Capital Management, LLCActive

Some overlap · 3 shared positions

$TYRA $EYPT $TARA

$604M

59 positions

#13Ikarian Capital, LLCActive

Some overlap · 4 shared positions

$CLDX $BHVN $PHVS $TECX

$928M

156 positions

#14TFG Asset Management GP LtdSmart money

Some overlap · 4 shared positions

$SLN $CLDX $PHVS $TECX

$635M

39 positions

#15Redmile Group, LLCSmart money

Some overlap · 3 shared positions

$SLN $CLDX $ALXO

$1.5B

39 positions

#16Vivo Capital, LLCActive

Slight overlap · 3 shared positions

$CAMP $SRZN $ALXO

$1.1B

47 positions

#17Paradigm Biocapital Advisors LPActive

Slight overlap · 3 shared positions

$TYRA $EYPT $MPLT

$5.3B

28 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.