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Hedge Funds Similar to 5AM Venture ,

13F Portfolio OverlapQ1 20265AM Venture , portfolio →
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Most similar hedge funds by 13F overlap

5AM Venture Management, LLC is an institutional investor managing $360M across 20 U.S. equity positions as of Q1 2026. Based on the overlap of conviction holdings in their latest 13F filings, the hedge funds with portfolios most similar to 5AM Venture , are Vivo ,, Commodore, Logos Global, with shared positions in $ERAS, $CAMP, $SRZN, $ALXO, $TYRA, $CLDX. The full ranking of 25 similar funds is below.

#1Vivo Capital, LLCActive
Notable overlap · 4 shared positions
$ERAS$CAMP$SRZN$ALXO
$1.2B
45 positions
#2Commodore Capital LPActive
Notable overlap · 5 shared positions
$TYRA$CLDX$PHVS$ERAS$EYPT
$1.7B
36 positions
#3Logos Global Management LPActive
Notable overlap · 4 shared positions
$ERAS$CNTA$TYRA$CLDX
$2.0B
66 positions
#4TCG Crossover Management, LLCActive
Notable overlap · 8 shared positions
$CNTA$TYRA$SRZN$BHVN$TECX$TRDA
$3.5B
49 positions
#5Cormorant Asset Management, LPActive
Notable overlap · 5 shared positions
$ERAS$EYPT$CNTA$PHVS$BHVN
$2.0B
47 positions
#6Novo Holdings A/SActive
Notable overlap · 3 shared positions
$MPLT$PHVS$CLDX
$1.2B
22 positions
#7Elmind Capital, LPActive
Notable overlap · 3 shared positions
$CLDX$PHVS$TYRA
$352M
34 positions
#8Kalehua Capital Management LLCActive
Notable overlap · 3 shared positions
$PHVS$SRZN$TYRA
$119M
23 positions
#9VR Adviser, LLCSmart money
Notable overlap · 3 shared positions
$ERAS$SRZN$ARTV
$2.7B
33 positions
#10Foresite Capital Management VI LLCActive
Notable overlap · 3 shared positions
$CNTA$CLDX$GHRS
$460M
17 positions
#11Spruce Street Capital LPActive
Notable overlap · 3 shared positions
$CNTA$SRZN$ERAS
$416M
28 positions
#12Affinity Asset Advisors, LLCActive
Notable overlap · 3 shared positions
$ERAS$CNTA$CLDX
$1.9B
105 positions
#13venBio Partners LLCSmart money
Notable overlap · 3 shared positions
$PHVS$ALXO$ARTV
$281M
6 positions
#14Seven Fleet Capital Management LPActive
Notable overlap · 3 shared positions
$TYRA$PHVS$ERAS
$315M
114 positions
#15Paradigm Biocapital Advisors LPActive
Notable overlap · 4 shared positions
$ERAS$CNTA$TYRA$EYPT
$4.9B
35 positions
#16ACUTA CAPITAL PARTNERS, LLCActive
Notable overlap · 3 shared positions
$ERAS$SRZN$TRDA
$142M
27 positions
#17StemPoint Capital LPActive
Some overlap · 5 shared positions
$EYPT$BHVN$CLDX$TYRA$SRZN
$515M
82 positions
#18Sio Capital Management, LLCActive
Some overlap · 4 shared positions
$TYRA$TARA$BHVN$EYPT
$697M
76 positions
#19Velan Capital Investment Management LPActive
Some overlap · 3 shared positions
$MPLT$TARA$ARTV
$160M
49 positions
#20SUPERSTRING CAPITAL MANAGEMENT LPActive
Some overlap · 3 shared positions
$CLDX$MPLT$TARA
$140M
35 positions
#21EcoR1 Capital, LLCSmart money
Some overlap · 3 shared positions
$CNTA$ERAS$SRZN
$2.4B
30 positions
#22Stonepine Capital Management, LLCActive
Some overlap · 3 shared positions
$CAMP$SRZN$ZNTL
$250M
83 positions
#23RA CAPITAL MANAGEMENT, L.P.Smart money
Some overlap · 3 shared positions
$TYRA$GHRS$ARTV
$9.4B
85 positions
#24SILVERARC CAPITAL MANAGEMENT, LLCActive
Some overlap · 3 shared positions
$ERAS$CNTA$CLDX
$980M
73 positions
#25SUVRETTA CAPITAL MANAGEMENT, LLCActive
Some overlap · 3 shared positions
$EYPT$BHVN$ERAS
$3.9B
89 positions

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Similarity is derived from each fund’s latest 13F-HR filing with the SEC. Funds are ranked by the overlap of distinctive conviction holdings; near-universal mega-cap positions are excluded so the ranking reflects shared strategy, not common index exposure. Data is informational only and not investment advice.