X4 Pharmaceuticals, Inc (XFOR) — Institutional Holders, Q2 2026
89 institutional investment managers reported a XFOR position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $463.0M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
XFOR in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- BlackRockAdded · +4,343,112 sh+$20.3M
- VR AdviserAdded · +1,603,728 sh+$7.5M
- PERCEPTIVE ADVISORSAdded · +1,195,843 sh+$5.6M
- GEODE CAPITAL MANAGEMENTAdded · +1,158,321 sh+$5.4M
- STATE STREETAdded · +892,483 sh+$4.2M
Biggest sellers
- Empery Asset ManagementTrimmed · -2,013,527 sh-$9.4M
- MILLENNIUM MANAGEMENTSold out · -1,210,514 sh-$5.7M
- StemPoint CapitalSold out · -850,742 sh-$4.0M
- SUSQUEHANNA INTERNATIONAL GROUP, LLPTrimmed · -842,172 sh-$3.9M
- Deep Track CapitalTrimmed · -460,778 sh-$2.2M
XFOR 13F holders ranked 1–89 of 89
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | MORGAN STANLEY#1 · 9,461,279 sh | 9,461,279 | $44.2M | <0.01% | -0.1% |
| 2 | FMR#2 · 8,321,657 sh | 8,321,657 | $38.9M | <0.01% | +2.7% |
| 3 | Bain Capital Life Sciences Investors#3 · 7,967,454 sh | 7,967,454 | $37.2M | 2.21% | 0.0% |
| 4 | PERCEPTIVE ADVISORS#4 · 7,933,491 sh | 7,933,491 | $37.0M | 0.56% | +17.7% |
| 5 | Saturn V Capital Management#5 · 6,973,343 sh | 6,973,343 | $32.6M | 4.67% | +8.0% |
| 6 | Empery Asset Management#6 · 6,930,591 sh | 6,930,591 | $32.4M | 37.43% | -22.5% |
| 7 | Deep Track Capital#7 · 5,878,757 sh | 5,878,757 | $27.5M | 0.40% | -7.3% |
| 8 | BlackRock#8 · 5,554,906 sh | 5,554,906 | $25.9M | <0.01% | +358.4% |
| 9 | Kalehua Capital Management#9 · 3,722,840 sh | 3,722,840 | $17.4M | 12.46% | 0.0% |
| 10 | VANGUARD CAPITAL MANAGEMENT#10 · 3,715,859 sh | 3,715,859 | $17.4M | <0.01% | +6.2% |
| 11 | NEA Management Company#11 · 3,233,743 sh | 3,233,743 | $15.1M | 0.95% | 0.0% |
| 12 | Rosalind Advisors#12 · 3,214,766 sh | 3,214,766 | $15.0M | 3.96% | 0.0% |
| 13 | BRAIDWELL#13 · 2,922,754 sh | 2,922,754 | $13.6M | 0.50% | -10.7% |
| 14 | Blackstone#14 · 2,681,922 sh | 2,681,922 | $12.5M | 0.03% | 0.0% |
| 15 | Trails Edge Capital Partners#15 · 2,571,478 sh | 2,571,478 | $12.0M | 1.91% | 0.0% |
| 16 | Nantahala Capital Management#16 · 2,449,468 sh | 2,449,468 | $11.4M | 0.38% | 0.0% |
| 17 | BVF#17 · 2,233,742 sh | 2,233,742 | $10.4M | 0.27% | 0.0% |
| 18 | GEODE CAPITAL MANAGEMENT#18 · 2,098,047 sh | 2,098,047 | $9.8M | <0.01% | +123.3% |
| 19 | VR Adviser#19 · 1,934,253 sh | 1,934,253 | $9.0M | 0.27% | +485.2% |
| 20 | Samsara BioCapital#20 · 1,395,587 sh | 1,395,587 | $6.5M | 0.54% | -23.8% |
| 21 | STATE STREET#21 · 1,296,017 sh | 1,296,017 | $6.1M | <0.01% | +221.2% |
| 22 | Woodline Partners#22 · 1,001,095 sh | 1,001,095 | $4.7M | 0.01% | 0.0% |
| 23 | GOLDMAN SACHS GROUP#23 · 916,536 sh | 916,536 | $4.3M | <0.01% | +3.9% |
| 24 | NORTHERN#24 · 652,849 sh | 652,849 | $3.0M | <0.01% | +266.3% |
| 25 | VANGUARD FIDUCIARY#25 · 572,038 sh | 572,038 | $2.7M | <0.01% | +19.0% |
| 26 | VANGUARD PORTFOLIO MANAGEMENT#26 · 542,128 sh | 542,128 | $2.5M | <0.01% | New |
| 27 | Verdad Advisers#27 · 352,093 sh | 352,093 | $1.6M | 1.57% | New |
| 28 | CHARLES SCHWAB INVESTMENT MANAGEMENT#28 · 263,264 sh | 263,264 | $1.2M | <0.01% | +294.4% |
| 29 | Stonepine Capital Management#29 · 224,989 sh | 224,989 | $1.1M | 0.49% | -32.9% |
| 30 | Bank of New York Mellon#30 · 196,340 sh | 196,340 | $916.9K | <0.01% | New |
| 31 | Affinity Asset Advisors#31 · 145,000 sh | 145,000 | $677.1K | 0.03% | 0.0% |
| 32 | Nuveen#32 · 107,389 sh | 107,389 | $501.5K | <0.01% | New |
| 33 | Invesco Ltd.#33 · 96,772 sh | 96,772 | $451.9K | 0.00% | +384.6% |
| 34 | ALPS ADVISORS#34 · 95,726 sh | 95,726 | $447.0K | <0.01% | New |
| 35 | RHUMBLINE ADVISERS#35 · 95,081 sh | 95,081 | $444.0K | <0.01% | New |
| 36 | Susquehanna Portfolio Strategies#36 · 87,282 sh | 87,282 | $407.6K | <0.01% | -14.9% |
| 37 | DEUTSCHE BANK AG\#37 · 78,885 sh | 78,885 | $368.4K | <0.01% | New |
| 38 | GSA CAPITAL PARTNERS LLP#38 · 76,314 sh | 76,314 | $356.0K | 0.02% | New |
| 39 | AMERICAN CENTURY COMPANIES#39 · 74,795 sh | 74,795 | $349.3K | <0.01% | New |
| 40 | CITIGROUP#40 · 70,112 sh | 70,112 | $327.4K | <0.01% | +96.0% |
| 41 | WELLS FARGO & COMPANY#41 · 67,712 sh | 67,712 | $316.2K | <0.01% | New |
| 42 | Palumbo Wealth Management#42 · 67,116 sh | 67,116 | $313.4K | 0.07% | -48.8% |
| 43 | Squarepoint Ops#43 · 67,078 sh | 67,078 | $313.3K | <0.01% | New |
| 44 | PRICE T ROWE ASSOCIATES#44 · 66,379 sh | 66,379 | $310.0K | 0.00% | New |
| 45 | UBS Group AG#45 · 58,043 sh | 58,043 | $271.1K | 0.00% | -78.3% |
| 46 | WELLINGTON MANAGEMENT GROUP LLP#46 · 51,800 sh | 51,800 | $241.9K | 0.00% | New |
| 47 | MetLife Investment Management#47 · 47,969 sh | 47,969 | $224.0K | <0.01% | New |
| 48 | BANK OF AMERICA#48 · 46,861 sh | 46,861 | $218.8K | 0.00% | -68.9% |
| 49 | Point72 Asset Management, L.P.#49 · 41,072 sh | 41,072 | $191.8K | <0.01% | New |
| 50 | MIRAE ASSET GLOBAL ETFS Ltd.#50 · 37,073 sh | 37,073 | $173.1K | <0.01% | New |
| 51 | Jump Financial#51 · 34,253 sh | 34,253 | $160.0K | <0.01% | +178.1% |
| 52 | Vanguard Global Advisers#52 · 32,977 sh | 32,977 | $154.0K | <0.01% | 0.0% |
| 53 | JPMORGAN CHASE#53 · 33,552 sh | 33,552 | $141.9K | 0.00% | New |
| 54 | Police & Firemen's Retirement System of New Jersey#54 · 23,846 sh | 23,846 | $111.4K | <0.01% | New |
| 55 | AXQ CAPITAL#55 · 22,880 sh | 22,880 | $106.8K | 0.01% | New |
| 56 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#56 · 22,083 sh | 22,083 | $103.1K | <0.01% | New |
| 57 | BARCLAYS PLC#57 · 19,439 sh | 19,439 | $90.8K | 0.00% | +590.8% |
| 58 | TWO SIGMA INVESTMENTS#58 · 19,426 sh | 19,426 | $90.7K | <0.01% | +40.1% |
| 59 | STIFEL FINANCIAL#59 · 18,519 sh | 18,519 | $86.5K | <0.01% | -15.0% |
| 60 | RENAISSANCE TECHNOLOGIES#60 · 18,100 sh | 18,100 | $84.5K | <0.01% | New |
| 61 | INTECH INVESTMENT MANAGEMENT#61 · 17,290 sh | 17,290 | $80.7K | <0.01% | New |
| 62 | NEW YORK STATE COMMON RETIREMENT FUND#62 · 16,500 sh | 16,500 | $77.1K | <0.01% | New |
| 63 | BNP PARIBAS FINANCIAL MARKETS#63 · 16,384 sh | 16,384 | $76.5K | 0.00% | +244.5% |
| 64 | VOYA INVESTMENT MANAGEMENT#64 · 15,838 sh | 15,838 | $74.0K | <0.01% | New |
| 65 | CAXTON#65 · 15,557 sh | 15,557 | $72.7K | 3.92% | 0.0% |
| 66 | WINTON GROUP Ltd#66 · 14,400 sh | 14,400 | $67.2K | <0.01% | +35.8% |
| 67 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#67 · 14,050 sh | 14,050 | $65.6K | 0.00% | -98.4% |
| 68 | Creative Planning#68 · 13,872 sh | 13,872 | $64.8K | 0.00% | +0.4% |
| 69 | ALLIANCEBERNSTEIN L.P.#69 · 14,580 sh | 14,580 | $60.2K | 0.00% | New |
| 70 | PRUDENTIAL FINANCIAL#70 · 12,500 sh | 12,500 | $58.4K | <0.01% | New |
| 71 | ProShare Advisors#71 · 10,588 sh | 10,588 | $49.4K | <0.01% | New |
| 72 | Indivisible Partners#72 · 10,000 sh | 10,000 | $46.9K | — | 0.0% |
| 73 | Pettinga Financial Advisors#73 · 10,000 sh | 10,000 | $46.7K | — | New |
| 74 | Legal & General Group Plc#74 · 7,858 sh | 7,858 | $36.7K | 0.00% | New |
| 75 | Tower Research Capital (TRC)#75 · 7,745 sh | 7,745 | $36.2K | <0.01% | +4202.8% |
| 76 | Ameritas Investment Partners#76 · 7,338 sh | 7,338 | $34.3K | <0.01% | New |
| 77 | Russell Investments Group, Ltd.#77 · 7,178 sh | 7,178 | $33.5K | 0.00% | +884.6% |
| 78 | ROYAL BANK OF CANADA#78 · 2,559 sh | 2,559 | $12.0K | 0.00% | +2125.2% |
| 79 | PNC FINANCIAL SERVICES GROUP#79 · 1,759 sh | 1,759 | $8.2K | 0.00% | 0.0% |
| 80 | Sterling Capital Management#80 · 1,629 sh | 1,629 | $7.6K | — | New |
| 81 | GROUP ONE TRADING, L.P.#81 · 712 sh | 712 | $3.3K | 0.00% | 0.0% |
| 82 | Bleichroeder#82 · 595 sh | 595 | $2.8K | <0.01% | 0.0% |
| 83 | Ronald Blue#83 · 284 sh | 284 | $1.3K | — | 0.0% |
| 84 | Rockefeller Capital Management L.P.#84 · 33 sh | 33 | $154.00 | 0.00% | 0.0% |
| 85 | JONES FINANCIAL COMPANIES LLLP#85 · 38 sh | 38 | $153.00 | 0.00% | 0.0% |
| 86 | Caitong International Asset Management , Ltd#86 · 30 sh | 30 | $140.00 | 0.00% | New |
| 87 | SBI Securities , Ltd.#87 · 9 sh | 9 | $42.00 | — | -83.3% |
| 88 | HighMark Wealth Management#88 · 6 sh | 6 | $28.00 | 0.00% | 0.0% |
| 89 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM#89 · 1,113 sh | 1,113 | — | — | New |
Funds that sold out of XFOR in Q2 2026 (26)
Held XFOR at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| MILLENNIUM MANAGEMENT1,210,514 sh | 1,210,514 | $5.0M |
| StemPoint Capital850,742 sh | 850,742 | $3.5M |
| MARSHALL WACE, LLP336,834 sh | 336,834 | $1.4M |
| Qube Research & Technologies Ltd218,954 sh | 218,954 | $904.3K |
| Pale Fire Capital SE167,590 sh | 167,590 | $692.1K |
| Brevan Howard Capital Management127,321 sh | 127,321 | $525.8K |
| Dynamic Technology Lab Private Ltd36,221 sh | 36,221 | $384.7K |
| OMERS ADMINISTRATION57,300 sh | 57,300 | $236.6K |
| Hudson Bay Capital Management50,287 sh | 50,287 | $207.7K |
| Catalyst Funds Management Pty Ltd47,383 sh | 47,383 | $195.7K |
| JANE STREET GROUP37,143 sh | 37,143 | $153.4K |
| Diametric Capital28,973 sh | 28,973 | $119.7K |
| Schonfeld Strategic Advisors19,514 sh | 19,514 | $80.6K |
| LEUCADIA NATIONAL19,474 sh | 19,474 | $80.4K |
| ExodusPoint Capital Management14,703 sh | 14,703 | $60.7K |
| Virtu Financial12,730 sh | 12,730 | $53.0K |
| QUADRANT CAPITAL GROUP256 sh | 256 | $49.5K |
| Vanguard Personalized Indexing Management11,525 sh | 11,525 | $47.6K |
| SummitTX Capital, L.P.11,200 sh | 11,200 | $46.3K |
| SIGNATUREFD1,996 sh | 1,996 | $8.2K |
| State of Wyoming1,065 sh | 1,065 | $4.4K |
| ACADIAN ASSET MANAGEMENT802 sh | 802 | $3.0K |
| Farther Finance Advisors331 sh | 331 | $1.4K |
| Allworth Financial310 sh | 310 | $1.3K |
| Parallel Advisors116 sh | 116 | $479.00 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT5 sh | 5 | $21.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.