Xeris Biopharma Holdings, Inc. (XERS) — Institutional Holders, Q2 2026
244 institutional investment managers reported a XERS position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $946.8M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
XERS in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- VANGUARD CAPITAL MANAGEMENTNew · +7,340,229 sh+$58.1M
- VANGUARD PORTFOLIO MANAGEMENTNew · +2,626,208 sh+$20.8M
- BlackRockAdded · +1,579,754 sh+$12.5M
- NuveenAdded · +1,468,543 sh+$11.6M
- VANGUARD FIDUCIARYNew · +1,224,398 sh+$9.7M
Biggest sellers
- MILLENNIUM MANAGEMENTTrimmed · -2,134,310 sh-$16.9M
- Voss CapitalSold out · -1,386,927 sh-$11.0M
- Qube Research & Technologies LtdTrimmed · -1,220,676 sh-$9.7M
- CenterBook PartnersTrimmed · -968,056 sh-$7.7M
- DRIEHAUS CAPITAL MANAGEMENTSold out · -902,740 sh-$7.1M
XERS 13F holders ranked 1–100 of 244
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | BlackRock#1 · 14,525,539 sh | 14,525,539 | $115.0M | <0.01% | +12.2% |
| 2 | CAPSTONE INVESTMENT ADVISORS#2 · 23,074,000 sh | 23,074,000 | $62.6M | 0.06% | 0.0% |
| 3 | D. E. Shaw#3 · 7,804,758 sh | 7,804,758 | $61.8M | 0.03% | +0.2% |
| 4 | VANGUARD CAPITAL MANAGEMENT#4 · 7,340,229 sh | 7,340,229 | $58.1M | <0.01% | New |
| 5 | STATE STREET#5 · 4,821,566 sh | 4,821,566 | $38.2M | <0.01% | +3.5% |
| 6 | GEODE CAPITAL MANAGEMENT#6 · 4,718,183 sh | 4,718,183 | $37.4M | <0.01% | +10.0% |
| 7 | Nuveen#7 · 4,385,141 sh | 4,385,141 | $34.7M | <0.01% | +50.4% |
| 8 | Polar Asset Management Partners#8 · 10,500,000 sh | 10,500,000 | $28.8M | 0.47% | 0.0% |
| 9 | Rosalind Advisors#9 · 2,908,981 sh | 2,908,981 | $23.0M | 6.08% | -10.0% |
| 10 | Qube Research & Technologies Ltd#10 · 2,893,749 sh | 2,893,749 | $22.9M | 0.02% | -29.7% |
| 11 | VANGUARD PORTFOLIO MANAGEMENT#11 · 2,626,208 sh | 2,626,208 | $20.8M | <0.01% | New |
| 12 | WELLINGTON MANAGEMENT GROUP LLP#12 · 2,365,103 sh | 2,365,103 | $18.7M | <0.01% | +8.9% |
| 13 | MORGAN STANLEY#13 · 2,337,096 sh | 2,337,096 | $18.5M | <0.01% | -9.2% |
| 14 | Legal & General Group Plc#14 · 2,012,792 sh | 2,012,792 | $15.9M | <0.01% | +5.5% |
| 15 | ARMISTICE CAPITAL#15 · 1,958,702 sh | 1,958,702 | $15.5M | 0.19% | +2.6% |
| 16 | TWO SIGMA INVESTMENTS#16 · 1,885,503 sh | 1,885,503 | $14.9M | 0.01% | -2.0% |
| 17 | Parkman Healthcare Partners#17 · 1,807,621 sh | 1,807,621 | $14.3M | 1.47% | +5.0% |
| 18 | ALGERT GLOBAL#18 · 1,742,942 sh | 1,742,942 | $13.8M | 0.16% | +50.6% |
| 19 | NORTHERN#19 · 1,597,749 sh | 1,597,749 | $12.7M | <0.01% | +10.6% |
| 20 | GOLDMAN SACHS GROUP#20 · 1,594,072 sh | 1,594,072 | $12.6M | <0.01% | -1.2% |
| 21 | AQR CAPITAL MANAGEMENT#21 · 1,540,985 sh | 1,540,985 | $12.2M | <0.01% | +10.5% |
| 22 | CHARLES SCHWAB INVESTMENT MANAGEMENT#22 · 1,492,367 sh | 1,492,367 | $11.8M | <0.01% | +9.8% |
| 23 | FEDERATED HERMES#23 · 1,434,433 sh | 1,434,433 | $11.4M | 0.02% | +67.4% |
| 24 | BANK OF AMERICA#24 · 1,397,050 sh | 1,397,050 | $11.1M | <0.01% | +59.8% |
| 25 | UBS Group AG#25 · 1,300,913 sh | 1,300,913 | $10.3M | <0.01% | -21.0% |
| 26 | Ishara Investments#26 · 1,230,000 sh | 1,230,000 | $9.7M | 7.16% | +20.0% |
| 27 | VANGUARD FIDUCIARY#27 · 1,224,398 sh | 1,224,398 | $9.7M | <0.01% | New |
| 28 | KENNEDY CAPITAL MANAGEMENT#28 · 1,209,068 sh | 1,209,068 | $9.6M | 0.17% | -2.5% |
| 29 | DIMENSIONAL FUND ADVISORS#29 · 1,073,639 sh | 1,073,639 | $8.5M | <0.01% | New |
| 30 | Knott David M Jr#30 · 1,060,000 sh | 1,060,000 | $8.4M | 4.44% | 0.0% |
| 31 | JPMORGAN CHASE#31 · 1,058,067 sh | 1,058,067 | $8.2M | <0.01% | +72.8% |
| 32 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP#32 · 972,880 sh | 972,880 | $7.7M | <0.01% | +627.3% |
| 33 | Granahan Investment Management#33 · 898,753 sh | 898,753 | $7.1M | 0.25% | -2.5% |
| 34 | NORGES BANK#34 · 797,200 sh | 797,200 | $6.3M | <0.01% | — |
| 35 | ESSEX INVESTMENT MANAGEMENT#35 · 715,608 sh | 715,608 | $5.7M | — | -4.3% |
| 36 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#36 · 687,632 sh | 687,632 | $5.4M | <0.01% | +2.9% |
| 37 | VOYA INVESTMENT MANAGEMENT#37 · 685,570 sh | 685,570 | $5.4M | <0.01% | +9.6% |
| 38 | CITADEL ADVISORS#38 · 664,564 sh | 664,564 | $5.3M | <0.01% | -2.5% |
| 39 | FMR#39 · 644,057 sh | 644,057 | $5.1M | <0.01% | +25.5% |
| 40 | Walleye Capital#40 · 611,296 sh | 611,296 | $4.8M | 0.02% | New |
| 41 | DEUTSCHE BANK AG\#41 · 529,443 sh | 529,443 | $4.2M | <0.01% | -15.0% |
| 42 | Bank of New York Mellon#42 · 488,441 sh | 488,441 | $3.9M | <0.01% | +14.6% |
| 43 | FIRST ADVISORS#43 · 484,978 sh | 484,978 | $3.8M | <0.01% | New |
| 44 | IHT Wealth Management#44 · 481,871 sh | 481,871 | $3.8M | 0.08% | +28.0% |
| 45 | PERCEPTIVE ADVISORS#45 · 467,013 sh | 467,013 | $3.7M | 0.06% | New |
| 46 | ROYCE & ASSOCIATES#46 · 461,153 sh | 461,153 | $3.7M | 0.03% | +80.1% |
| 47 | Man Group plc#47 · 455,380 sh | 455,380 | $3.6M | <0.01% | +64.7% |
| 48 | Russell Investments Group, Ltd.#48 · 440,731 sh | 440,731 | $3.5M | <0.01% | +14.7% |
| 49 | BNP PARIBAS FINANCIAL MARKETS#49 · 430,488 sh | 430,488 | $3.4M | <0.01% | +63.8% |
| 50 | STATE OF WISCONSIN INVESTMENT BOARD#50 · 427,513 sh | 427,513 | $3.4M | <0.01% | +38.6% |
| 51 | Jupiter Topco#51 · 414,959 sh | 414,959 | $3.3M | <0.01% | — |
| 52 | Y-Intercept (Hong Kong) Ltd#52 · 411,346 sh | 411,346 | $3.3M | — | +154.2% |
| 53 | Squarepoint Ops#53 · 365,731 sh | 365,731 | $2.9M | <0.01% | -40.5% |
| 54 | HRT FINANCIAL#54 · 365,659 sh | 365,659 | $2.9M | <0.01% | +113.7% |
| 55 | SEI INVESTMENTS#55 · 339,509 sh | 339,509 | $2.7M | <0.01% | -41.4% |
| 56 | Trexquant Investment#56 · 339,113 sh | 339,113 | $2.7M | 0.02% | -59.3% |
| 57 | Swiss National Bank#57 · 337,500 sh | 337,500 | $2.7M | <0.01% | +2.8% |
| 58 | Schonfeld Strategic Advisors#58 · 318,177 sh | 318,177 | $2.5M | <0.01% | +7.3% |
| 59 | RICE HALL JAMES & ASSOCIATES#59 · 300,791 sh | 300,791 | $2.4M | 0.12% | +19.8% |
| 60 | LEUCADIA NATIONAL#60 · 293,670 sh | 293,670 | $2.3M | 0.02% | +234.5% |
| 61 | CenterBook Partners#61 · 280,565 sh | 280,565 | $2.2M | 0.11% | -77.5% |
| 62 | PRICE T ROWE ASSOCIATES#62 · 266,877 sh | 266,877 | $2.1M | <0.01% | +27.7% |
| 63 | HEALTHCARE OF ONTARIO PENSION PLAN FUND#63 · 263,537 sh | 263,537 | $2.1M | <0.01% | -43.2% |
| 64 | Cliffwater#64 · 263,158 sh | 263,158 | $2.1M | 0.52% | New |
| 65 | Apella Capital#65 · 215,897 sh | 215,897 | $1.9M | — | -8.5% |
| 66 | Legato Capital Management#66 · 241,341 sh | 241,341 | $1.9M | 0.16% | +3.1% |
| 67 | PANAGORA ASSET MANAGEMENT#67 · 227,579 sh | 227,579 | $1.8M | <0.01% | +117.3% |
| 68 | PRINCIPAL FINANCIAL GROUP#68 · 227,418 sh | 227,418 | $1.8M | <0.01% | +9.1% |
| 69 | GROUP ONE TRADING, L.P.#69 · 226,607 sh | 226,607 | $1.8M | <0.01% | +3.9% |
| 70 | CANADA PENSION PLAN INVESTMENT BOARD#70 · 219,200 sh | 219,200 | $1.7M | <0.01% | -41.5% |
| 71 | RHUMBLINE ADVISERS#71 · 214,205 sh | 214,205 | $1.7M | <0.01% | +12.1% |
| 72 | COMMONWEALTH EQUITY SERVICES#72 · 205,855 sh | 205,855 | $1.6M | <0.01% | +1.3% |
| 73 | Voleon Capital Management#73 · 204,732 sh | 204,732 | $1.6M | 0.03% | +340.2% |
| 74 | RAYMOND JAMES FINANCIAL#74 · 202,911 sh | 202,911 | $1.6M | <0.01% | -2.6% |
| 75 | Aquatic Capital Management#75 · 199,983 sh | 199,983 | $1.6M | 0.05% | New |
| 76 | Caption Management#76 · 197,863 sh | 197,863 | $1.6M | <0.01% | -3.5% |
| 77 | Corient Private Wealth#77 · 184,126 sh | 184,126 | $1.5M | <0.01% | New |
| 78 | Virtus Investment Advisers#78 · 171,264 sh | 171,264 | $1.4M | 0.32% | +350.3% |
| 79 | BARCLAYS PLC#79 · 166,566 sh | 166,566 | $1.3M | <0.01% | +20.2% |
| 80 | WELLS FARGO & COMPANY#80 · 157,487 sh | 157,487 | $1.2M | <0.01% | +170.1% |
| 81 | Creative Planning#81 · 154,059 sh | 154,059 | $1.2M | <0.01% | +15.6% |
| 82 | Quarry#82 · 150,057 sh | 150,057 | $1.2M | 0.10% | +20.0% |
| 83 | GLOBEFLEX CAPITAL L P#83 · 145,917 sh | 145,917 | $1.2M | 0.15% | +18.5% |
| 84 | AMERIPRISE FINANCIAL#84 · 143,285 sh | 143,285 | $1.1M | <0.01% | +0.8% |
| 85 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#85 · 139,918 sh | 139,918 | $1.1M | <0.01% | -51.1% |
| 86 | CITIGROUP#86 · 134,298 sh | 134,298 | $1.1M | <0.01% | +53.8% |
| 87 | VANGUARD ASSET MANAGEMENT, Ltd#87 · 133,417 sh | 133,417 | $1.1M | <0.01% | New |
| 88 | DIADEMA PARTNERS#88 · 132,746 sh | 132,746 | $1.1M | 0.13% | 0.0% |
| 89 | MILLENNIUM MANAGEMENT#89 · 131,664 sh | 131,664 | $1.0M | <0.01% | -94.2% |
| 90 | LPL Financial#90 · 128,941 sh | 128,941 | $1.0M | <0.01% | +37.4% |
| 91 | Connor, Clark & Lunn Investment Management Ltd.#91 · 127,107 sh | 127,107 | $1.0M | <0.01% | -68.8% |
| 92 | Gotham Asset Management#92 · 123,914 sh | 123,914 | $981.4K | <0.01% | +186.5% |
| 93 | Quantbot Technologies#93 · 111,102 sh | 111,102 | $879.9K | 0.03% | +295.9% |
| 94 | Invesco Ltd.#94 · 109,875 sh | 109,875 | $870.2K | <0.01% | +6.4% |
| 95 | ALLIANCEBERNSTEIN L.P.#95 · 145,336 sh | 145,336 | $842.9K | <0.01% | 0.0% |
| 96 | Palo Alto Investors#96 · 104,410 sh | 104,410 | $826.9K | 0.11% | 0.0% |
| 97 | MetLife Investment Management#97 · 100,167 sh | 100,167 | $793.3K | <0.01% | +30.5% |
| 98 | IEQ CAPITAL#98 · 98,429 sh | 98,429 | $779.6K | <0.01% | +20.6% |
| 99 | AMERICAN CENTURY COMPANIES#99 · 93,345 sh | 93,345 | $739.3K | <0.01% | New |
| 100 | FRANKLIN RESOURCES#100 · 88,885 sh | 88,885 | $704.0K | <0.01% | +10.8% |
Funds that sold out of XERS in Q2 2026 (28)
Held XERS at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Voss Capital1,386,927 sh | 1,386,927 | $8.0M |
| DRIEHAUS CAPITAL MANAGEMENT902,740 sh | 902,740 | $5.2M |
| VOLORIDGE INVESTMENT MANAGEMENT370,116 sh | 370,116 | $2.1M |
| EMERALD MUTUAL FUND ADVISERS207,543 sh | 207,543 | $1.2M |
| F/m Investments207,543 sh | 207,543 | $1.2M |
| Engineers Gate Manager185,911 sh | 185,911 | $1.1M |
| Swiss Life Asset Management Ltd33,232 sh | 33,232 | $789.2K |
| TWINBEECH CAPITAL97,200 sh | 97,200 | $563.8K |
| Integrated Quantitative Investments66,170 sh | 66,170 | $383.8K |
| Stonepine Capital Management40,030 sh | 40,030 | $232.2K |
| DRW Securities36,807 sh | 36,807 | $213.5K |
| AIGEN INVESTMENT MANAGEMENT32,521 sh | 32,521 | $188.6K |
| ExodusPoint Capital Management25,685 sh | 25,685 | $149.0K |
| MIRABELLA FINANCIAL SERVICES LLP22,483 sh | 22,483 | $130.4K |
| DARK FOREST CAPITAL MANAGEMENT21,070 sh | 21,070 | $122.2K |
| Kemnay Advisory Services18,359 sh | 18,359 | $106.5K |
| Toroso Investments18,159 sh | 18,159 | $105.3K |
| Universal- Beteiligungs- und Servicegesellschaft mbH14,192 sh | 14,192 | $82.3K |
| R Squared Ltd13,802 sh | 13,802 | $80.1K |
| IMC-Chicago10,881 sh | 10,881 | $63.1K |
| Scientech Research10,414 sh | 10,414 | $60.4K |
| Allworth Financial2,315 sh | 2,315 | $13.4K |
| MAI Capital Management1,995 sh | 1,995 | $11.6K |
| Sound Income Strategies1,247 sh | 1,247 | $7.5K |
| Advisory Services Network1,000 sh | 1,000 | $5.8K |
| Aster Capital Management (DIFC) Ltd687 sh | 687 | $3.8K |
| FIFTH THIRD BANCORP280 sh | 280 | $1.6K |
| BESSEMER GROUP6 sh | 6 | $0.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.