SUTRO BIOPHARMA, INC. (STRO) — Institutional Holders, Q2 2026
100 institutional investment managers reported a STRO position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $545.7M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
STRO in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- BlackRockAdded · +889,971 sh+$29.5M
- PERCEPTIVE ADVISORSAdded · +589,539 sh+$19.6M
- MerckNew · +272,351 sh+$9.0M
- STATE STREETAdded · +253,861 sh+$8.4M
- BALYASNY ASSET MANAGEMENT L.P.Added · +245,370 sh+$8.1M
Biggest sellers
- RA CAPITAL MANAGEMENT, L.P.Sold out · -715,307 sh-$23.7M
- Point72 Asset Management, L.P.Trimmed · -454,284 sh-$15.1M
- ADAGE CAPITAL PARTNERS GP, L.L.C.Sold out · -200,000 sh-$6.6M
- Opaleye ManagementSold out · -190,671 sh-$6.3M
- UBS Group AGTrimmed · -184,359 sh-$6.1M
STRO 13F holders ranked 1–100 of 100
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | PERCEPTIVE ADVISORS#1 · 1,304,846 sh | 1,304,846 | $43.3M | 0.65% | +82.4% |
| 2 | BVF#2 · 1,251,788 sh | 1,251,788 | $41.6M | 1.06% | 0.0% |
| 3 | Affinity Asset Advisors#3 · 1,172,487 sh | 1,172,487 | $38.9M | 1.76% | +9.6% |
| 4 | BlackRock#4 · 1,122,655 sh | 1,122,655 | $37.3M | <0.01% | +382.5% |
| 5 | Samsara BioCapital#5 · 1,062,872 sh | 1,062,872 | $35.3M | 2.90% | 0.0% |
| 6 | Kynam Capital Management#6 · 872,558 sh | 872,558 | $29.0M | 1.60% | 0.0% |
| 7 | ORBIMED ADVISORS#7 · 743,944 sh | 743,944 | $24.7M | 0.46% | -7.1% |
| 8 | BALYASNY ASSET MANAGEMENT L.P.#8 · 711,162 sh | 711,162 | $23.6M | 0.03% | +52.7% |
| 9 | VANGUARD CAPITAL MANAGEMENT#9 · 694,219 sh | 694,219 | $23.0M | <0.01% | -3.6% |
| 10 | EVENTIDE ASSET MANAGEMENT#10 · 585,262 sh | 585,262 | $19.4M | 0.26% | -18.2% |
| 11 | Velan Capital Investment Management#11 · 512,160 sh | 512,160 | $17.0M | 10.36% | 0.0% |
| 12 | Woodline Partners#12 · 458,029 sh | 458,029 | $15.2M | 0.05% | +0.1% |
| 13 | ADAR1 Capital Management#13 · 404,014 sh | 404,014 | $13.4M | 0.61% | -23.0% |
| 14 | GEODE CAPITAL MANAGEMENT#14 · 389,692 sh | 389,692 | $12.9M | <0.01% | +127.4% |
| 15 | ACADIAN ASSET MANAGEMENT#15 · 373,839 sh | 373,839 | $12.4M | 0.01% | +11.3% |
| 16 | MILLENNIUM MANAGEMENT#16 · 365,972 sh | 365,972 | $12.2M | <0.01% | +74.0% |
| 17 | STATE STREET#17 · 305,979 sh | 305,979 | $10.2M | <0.01% | +487.1% |
| 18 | Merck#18 · 272,351 sh | 272,351 | $9.0M | 1.72% | 0.0% |
| 19 | ACUTA CAPITAL PARTNERS#19 · 270,251 sh | 270,251 | $9.0M | 6.25% | +0.3% |
| 20 | AMERIPRISE FINANCIAL#20 · 244,669 sh | 244,669 | $8.1M | <0.01% | New |
| 21 | Point72 Asset Management, L.P.#21 · 237,827 sh | 237,827 | $7.9M | <0.01% | -65.6% |
| 22 | KVP Capital Advisors#22 · 226,575 sh | 226,575 | $7.5M | 5.52% | 0.0% |
| 23 | UBS Group AG#23 · 208,512 sh | 208,512 | $6.9M | <0.01% | -46.9% |
| 24 | TWO SIGMA INVESTMENTS#24 · 201,688 sh | 201,688 | $6.7M | <0.01% | +209.5% |
| 25 | VANGUARD PORTFOLIO MANAGEMENT#25 · 197,562 sh | 197,562 | $6.6M | <0.01% | New |
| 26 | MARSHALL WACE, LLP#26 · 175,246 sh | 175,246 | $5.8M | <0.01% | -21.3% |
| 27 | Nuveen#27 · 167,997 sh | 167,997 | $5.6M | <0.01% | New |
| 28 | JPMORGAN CHASE#28 · 159,627 sh | 159,627 | $5.3M | <0.01% | New |
| 29 | GOLDMAN SACHS GROUP#29 · 149,216 sh | 149,216 | $5.0M | <0.01% | +448.9% |
| 30 | NORTHERN#30 · 125,933 sh | 125,933 | $4.2M | <0.01% | +279.7% |
| 31 | Seven Fleet Capital Management#31 · 159,118 sh | 159,118 | $3.8M | 0.63% | New |
| 32 | Qube Research & Technologies Ltd#32 · 106,610 sh | 106,610 | $3.5M | <0.01% | New |
| 33 | VANGUARD FIDUCIARY#33 · 104,232 sh | 104,232 | $3.5M | <0.01% | +9.9% |
| 34 | CITADEL ADVISORS#34 · 101,965 sh | 101,965 | $3.4M | <0.01% | -13.2% |
| 35 | MACKENZIE FINANCIAL#35 · 94,767 sh | 94,767 | $3.1M | <0.01% | New |
| 36 | RENAISSANCE TECHNOLOGIES#36 · 86,324 sh | 86,324 | $2.9M | <0.01% | -11.8% |
| 37 | Invesco Ltd.#37 · 57,305 sh | 57,305 | $1.9M | <0.01% | +233.8% |
| 38 | Y-Intercept (Hong Kong) Ltd#38 · 55,879 sh | 55,879 | $1.9M | — | New |
| 39 | Squarepoint Ops#39 · 55,539 sh | 55,539 | $1.8M | <0.01% | New |
| 40 | XTX Topco Ltd#40 · 52,169 sh | 52,169 | $1.7M | 0.02% | +536.0% |
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT#41 · 49,302 sh | 49,302 | $1.6M | <0.01% | +366.1% |
| 42 | Sigma Planning#42 · 45,020 sh | 45,020 | $1.5M | — | +259.6% |
| 43 | Bank of New York Mellon#43 · 41,369 sh | 41,369 | $1.4M | <0.01% | New |
| 44 | BARCLAYS PLC#44 · 36,954 sh | 36,954 | $1.2M | <0.01% | New |
| 45 | BANK OF AMERICA#45 · 36,140 sh | 36,140 | $1.2M | <0.01% | +91.5% |
| 46 | Fisher Asset Management#46 · 35,295 sh | 35,295 | $1.2M | <0.01% | 0.0% |
| 47 | Elmind Capital#47 · 32,037 sh | 32,037 | $1.1M | 0.27% | New |
| 48 | D. E. Shaw#48 · 30,128 sh | 30,128 | $1.0M | <0.01% | New |
| 49 | Trexquant Investment#49 · 27,636 sh | 27,636 | $917.5K | <0.01% | -19.5% |
| 50 | BNP PARIBAS FINANCIAL MARKETS#50 · 27,383 sh | 27,383 | $909.1K | <0.01% | New |
| 51 | RHUMBLINE ADVISERS#51 · 20,628 sh | 20,628 | $684.8K | <0.01% | New |
| 52 | GSA CAPITAL PARTNERS LLP#52 · 19,749 sh | 19,749 | $656.0K | 0.04% | -23.5% |
| 53 | SEI INVESTMENTS#53 · 16,387 sh | 16,387 | $544.0K | <0.01% | New |
| 54 | Informed Momentum#54 · 16,232 sh | 16,232 | $538.9K | 0.05% | New |
| 55 | DEUTSCHE BANK AG\#55 · 15,563 sh | 15,563 | $516.7K | <0.01% | New |
| 56 | RBF Capital#56 · 15,272 sh | 15,272 | $507.0K | 0.02% | 0.0% |
| 57 | PRICE T ROWE ASSOCIATES#57 · 13,597 sh | 13,597 | $452.0K | 0.00% | New |
| 58 | WELLS FARGO & COMPANY#58 · 13,544 sh | 13,544 | $449.7K | <0.01% | New |
| 59 | MORGAN STANLEY#59 · 12,356 sh | 12,356 | $410.2K | 0.00% | +17.4% |
| 60 | WELLINGTON MANAGEMENT GROUP LLP#60 · 10,800 sh | 10,800 | $358.6K | <0.01% | New |
| 61 | MetLife Investment Management#61 · 9,401 sh | 9,401 | $312.1K | <0.01% | New |
| 62 | Walleye Capital#62 · 9,306 sh | 9,306 | $309.0K | <0.01% | New |
| 63 | Integrated Quantitative Investments#63 · 8,939 sh | 8,939 | $296.8K | 0.05% | New |
| 64 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#64 · 8,426 sh | 8,426 | $279.7K | 0.00% | -90.1% |
| 65 | Lighthouse Investment Partners#65 · 8,368 sh | 8,368 | $277.8K | <0.01% | New |
| 66 | CITIGROUP#66 · 7,456 sh | 7,456 | $247.5K | <0.01% | -60.4% |
| 67 | MIRAE ASSET GLOBAL ETFS Ltd.#67 · 7,313 sh | 7,313 | $242.8K | <0.01% | New |
| 68 | ALLIANCEBERNSTEIN L.P.#68 · 7,300 sh | 7,300 | $242.4K | <0.01% | New |
| 69 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM#69 · 7,001 sh | 7,001 | $232.4K | <0.01% | New |
| 70 | Persistent Asset Partners Ltd#70 · 6,569 sh | 6,569 | $218.1K | 0.07% | -11.4% |
| 71 | Verdad Advisers#71 · 6,400 sh | 6,400 | $212.5K | 0.20% | New |
| 72 | HSBC PLC#72 · 6,234 sh | 6,234 | $205.7K | <0.01% | New |
| 73 | NEW YORK STATE COMMON RETIREMENT FUND#73 · 5,600 sh | 5,600 | $185.9K | <0.01% | New |
| 74 | Vanguard Global Advisers#74 · 5,445 sh | 5,445 | $180.8K | <0.01% | -24.2% |
| 75 | Police & Firemen's Retirement System of New Jersey#75 · 4,704 sh | 4,704 | $156.2K | <0.01% | New |
| 76 | Legal & General Group Plc#76 · 3,462 sh | 3,462 | $114.9K | 0.00% | New |
| 77 | State of Wyoming#77 · 1,618 sh | 1,618 | $53.7K | <0.01% | New |
| 78 | Ameritas Investment Partners#78 · 1,448 sh | 1,448 | $48.1K | <0.01% | New |
| 79 | FMR#79 · 1,339 sh | 1,339 | $44.5K | 0.00% | +27.5% |
| 80 | Russell Investments Group, Ltd.#80 · 1,275 sh | 1,275 | $42.3K | 0.00% | New |
| 81 | FNY Investment Advisers#81 · 1,000 sh | 1,000 | $33.0K | — | 0.0% |
| 82 | Tower Research Capital (TRC)#82 · 866 sh | 866 | $28.8K | <0.01% | New |
| 83 | ROYAL BANK OF CANADA#83 · 687 sh | 687 | $23.0K | 0.00% | +5625.0% |
| 84 | Owl Creek Wealth Partners#84 · 491 sh | 491 | $16.3K | — | 0.0% |
| 85 | Sterling Capital Management#85 · 281 sh | 281 | $9.3K | — | New |
| 86 | Quantbot Technologies#86 · 201 sh | 201 | $6.7K | <0.01% | New |
| 87 | Physician Wealth Advisors#87 · 182 sh | 182 | $6.0K | — | 0.0% |
| 88 | OSAIC#88 · 100 sh | 100 | $3.3K | 0.00% | -92.2% |
| 89 | PNC FINANCIAL SERVICES GROUP#89 · 62 sh | 62 | $2.1K | 0.00% | 0.0% |
| 90 | Fortitude Family Office#90 · 56 sh | 56 | $1.9K | — | 0.0% |
| 91 | Bogart Wealth#91 · 50 sh | 50 | $1.7K | <0.01% | 0.0% |
| 92 | Parallel Advisors#92 · 47 sh | 47 | $1.6K | 0.00% | 0.0% |
| 93 | NISA INVESTMENT ADVISORS#93 · 44 sh | 44 | $1.5K | — | 0.0% |
| 94 | Avion Wealth#94 · 46 sh | 46 | $1.0K | <0.01% | -36.1% |
| 95 | HighMark Wealth Management#95 · 23 sh | 23 | $763.00 | <0.01% | 0.0% |
| 96 | SRS Capital Advisors#96 · 16 sh | 16 | $531.00 | 0.00% | -61.0% |
| 97 | Steward Partners Investment Advisory#97 · 2 sh | 2 | $66.00 | 0.00% | New |
| 98 | Optiver Holding B.V.#98 · 2 sh | 2 | $66.00 | 0.00% | New |
| 99 | FIFTH THIRD BANCORP#99 · 2 sh | 2 | $66.00 | 0.00% | 0.0% |
| 100 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM#100 · 220 sh | 220 | — | — | New |
Funds that sold out of STRO in Q2 2026 (14)
Held STRO at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| RA CAPITAL MANAGEMENT, L.P.715,307 sh | 715,307 | $17.8M |
| ADAGE CAPITAL PARTNERS GP, L.L.C.200,000 sh | 200,000 | $5.0M |
| Opaleye Management190,671 sh | 190,671 | $4.7M |
| Eversept Partners73,161 sh | 73,161 | $1.8M |
| Burkehill Global Management71,530 sh | 71,530 | $1.8M |
| JANE STREET GROUP27,760 sh | 27,760 | $691.5K |
| StemPoint Capital23,295 sh | 23,295 | $580.3K |
| Brevan Howard Capital Management18,791 sh | 18,791 | $468.1K |
| Hudson Bay Capital Management14,768 sh | 14,768 | $367.9K |
| Jump Financial12,385 sh | 12,385 | $308.5K |
| OMERS ADMINISTRATION8,700 sh | 8,700 | $216.7K |
| AQR CAPITAL MANAGEMENT8,605 sh | 8,605 | $214.4K |
| State of Tennessee, Treasury Department7,400 sh | 7,400 | $184.3K |
| SIMPLEX TRADING62 sh | 62 | $1.5K |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.