Ultragenyx Pharmaceutical Inc. (RARE) — Institutional Holders, Q2 2026
311 institutional investment managers reported a RARE position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $3.5B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
RARE in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- RTW INVESTMENTSAdded · +4,148,100 sh+$138.5M
- BlackRockAdded · +3,354,678 sh+$112.0M
- AQR CAPITAL MANAGEMENTAdded · +1,982,785 sh+$66.2M
- JACOBS LEVY EQUITY MANAGEMENTAdded · +1,508,648 sh+$50.4M
- MPM BioImpactNew · +1,418,215 sh+$47.4M
Biggest sellers
- Assenagon Asset Management S.A.Trimmed · -2,136,807 sh-$71.3M
- CITADEL ADVISORSTrimmed · -1,904,960 sh-$63.6M
- Sofinnova VenturesTrimmed · -1,428,383 sh-$47.7M
- WELLINGTON MANAGEMENT GROUP LLPTrimmed · -1,390,348 sh-$46.4M
- Jones Hill CapitalSold out · -1,165,557 sh-$38.9M
RARE 13F holders ranked 1–100 of 311
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | BlackRock#1 · 10,654,276 sh | 10,654,276 | $355.7M | <0.01% | +46.0% |
| 2 | RTW INVESTMENTS#2 · 7,796,895 sh | 7,796,895 | $260.3M | 2.22% | +113.7% |
| 3 | VANGUARD PORTFOLIO MANAGEMENT#3 · 6,790,135 sh | 6,790,135 | $226.7M | 0.01% | +26.1% |
| 4 | AQR CAPITAL MANAGEMENT#4 · 6,560,809 sh | 6,560,809 | $214.1M | 0.07% | +43.3% |
| 5 | STATE STREET#5 · 6,158,766 sh | 6,158,766 | $205.6M | <0.01% | +22.6% |
| 6 | VANGUARD CAPITAL MANAGEMENT#6 · 4,296,491 sh | 4,296,491 | $143.5M | <0.01% | +2.5% |
| 7 | TWO SIGMA INVESTMENTS#7 · 3,621,200 sh | 3,621,200 | $120.9M | 0.09% | +64.2% |
| 8 | SANDS CAPITAL MANAGEMENT#8 · 3,158,368 sh | 3,158,368 | $105.5M | 0.39% | -1.7% |
| 9 | JACOBS LEVY EQUITY MANAGEMENT#9 · 2,939,719 sh | 2,939,719 | $98.2M | 0.35% | +105.4% |
| 10 | FRONTIER CAPITAL MANAGEMENT#10 · 2,847,936 sh | 2,847,936 | $95.1M | 0.89% | +30.0% |
| 11 | GEODE CAPITAL MANAGEMENT#11 · 2,578,828 sh | 2,578,828 | $86.1M | <0.01% | +39.4% |
| 12 | Bellevue Group AG#12 · 1,982,775 sh | 1,982,775 | $66.2M | 1.39% | -16.7% |
| 13 | D. E. Shaw#13 · 1,730,193 sh | 1,730,193 | $57.8M | 0.03% | +37.2% |
| 14 | Sofinnova Ventures#14 · 1,717,505 sh | 1,717,505 | $57.3M | 2.96% | -45.4% |
| 15 | ADAGE CAPITAL PARTNERS GP, L.L.C.#15 · 1,580,000 sh | 1,580,000 | $52.8M | 0.07% | +229.2% |
| 16 | GW&K Investment Management#16 · 1,481,178 sh | 1,481,178 | $49.5M | 0.39% | -8.3% |
| 17 | MPM BioImpact#17 · 1,418,215 sh | 1,418,215 | $47.4M | 2.89% | New |
| 18 | PRICE T ROWE ASSOCIATES#18 · 1,356,501 sh | 1,356,501 | $45.3M | <0.01% | +68.7% |
| 19 | MORGAN STANLEY#19 · 1,324,805 sh | 1,324,805 | $44.2M | <0.01% | -11.7% |
| 20 | WELLINGTON MANAGEMENT GROUP LLP#20 · 1,250,464 sh | 1,250,464 | $41.8M | <0.01% | -52.6% |
| 21 | VOLORIDGE INVESTMENT MANAGEMENT#21 · 1,241,556 sh | 1,241,556 | $41.5M | 0.18% | -13.0% |
| 22 | BANK OF AMERICA#22 · 1,148,454 sh | 1,148,454 | $38.3M | <0.01% | +9.7% |
| 23 | Candriam S.C.A.#23 · 1,001,841 sh | 1,001,841 | $33.4M | 0.15% | -8.6% |
| 24 | Rock Springs Capital Management#24 · 967,855 sh | 967,855 | $32.3M | 1.58% | -20.6% |
| 25 | LEUCADIA NATIONAL#25 · 929,626 sh | 929,626 | $31.0M | 0.20% | +5902.2% |
| 26 | NORTHERN#26 · 920,314 sh | 920,314 | $30.7M | <0.01% | +71.8% |
| 27 | Eagle Health Investments#27 · 884,121 sh | 884,121 | $29.5M | 4.89% | 0.0% |
| 28 | Qube Research & Technologies Ltd#28 · 882,219 sh | 882,219 | $29.5M | 0.03% | -3.6% |
| 29 | Russell Investments Group, Ltd.#29 · 784,099 sh | 784,099 | $26.2M | 0.02% | +94.6% |
| 30 | MILLENNIUM MANAGEMENT#30 · 760,825 sh | 760,825 | $25.4M | <0.01% | -57.1% |
| 31 | CHARLES SCHWAB INVESTMENT MANAGEMENT#31 · 760,039 sh | 760,039 | $25.4M | <0.01% | +36.1% |
| 32 | Nuveen#32 · 693,959 sh | 693,959 | $23.2M | <0.01% | +4.8% |
| 33 | Pictet Asset Management Holding SA#33 · 753,695 sh | 753,695 | $23.2M | 0.02% | +24.9% |
| 34 | VANGUARD FIDUCIARY#34 · 671,411 sh | 671,411 | $22.4M | <0.01% | +10.4% |
| 35 | UBS Group AG#35 · 657,699 sh | 657,699 | $22.0M | <0.01% | -21.0% |
| 36 | Palo Alto Investors#36 · 596,495 sh | 596,495 | $19.9M | 2.75% | 0.0% |
| 37 | SPHERA FUNDS MANAGEMENT LTD.#37 · 588,494 sh | 588,494 | $19.6M | 2.56% | -27.3% |
| 38 | Legal & General Group Plc#38 · 586,520 sh | 586,520 | $19.6M | <0.01% | -0.6% |
| 39 | PANAGORA ASSET MANAGEMENT#39 · 586,230 sh | 586,230 | $19.6M | 0.06% | New |
| 40 | FMR#40 · 576,849 sh | 576,849 | $19.3M | <0.01% | +100.8% |
| 41 | GOLDMAN SACHS GROUP#41 · 575,338 sh | 575,338 | $19.2M | <0.01% | +62.9% |
| 42 | Trexquant Investment#42 · 556,385 sh | 556,385 | $18.6M | 0.11% | +42.9% |
| 43 | BNP PARIBAS FINANCIAL MARKETS#43 · 498,167 sh | 498,167 | $16.6M | <0.01% | +1.5% |
| 44 | Bank of New York Mellon#44 · 470,697 sh | 470,697 | $15.7M | <0.01% | +38.0% |
| 45 | JPMORGAN CHASE#45 · 493,126 sh | 493,126 | $15.3M | <0.01% | +100.5% |
| 46 | TORONTO DOMINION BANK#46 · 415,000 sh | 415,000 | $13.9M | 0.02% | New |
| 47 | RENAISSANCE TECHNOLOGIES#47 · 413,700 sh | 413,700 | $13.8M | 0.02% | -26.3% |
| 48 | BNP Paribas Asset Management Holding S.A.#48 · 409,255 sh | 409,255 | $13.7M | 0.01% | -2.1% |
| 49 | Krensavage Asset Management#49 · 390,879 sh | 390,879 | $13.1M | 4.96% | 0.0% |
| 50 | ALGERT GLOBAL#50 · 389,964 sh | 389,964 | $13.0M | 0.15% | -9.0% |
| 51 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#51 · 381,420 sh | 381,420 | $12.7M | <0.01% | -15.5% |
| 52 | SummitTX Capital, L.P.#52 · 374,270 sh | 374,270 | $12.5M | 0.32% | +7.6% |
| 53 | Privium Fund Management B.V.#53 · 338,800 sh | 338,800 | $11.3M | 2.08% | -7.1% |
| 54 | Squarepoint Ops#54 · 338,368 sh | 338,368 | $11.3M | 0.01% | -23.9% |
| 55 | Walleye Capital#55 · 334,854 sh | 334,854 | $11.2M | 0.04% | +179.7% |
| 56 | Catalio Capital Management#56 · 316,252 sh | 316,252 | $10.6M | 1.98% | -62.8% |
| 57 | FRANKLIN RESOURCES#57 · 315,766 sh | 315,766 | $10.5M | <0.01% | +1.0% |
| 58 | CITIGROUP#58 · 298,785 sh | 298,785 | $10.0M | <0.01% | -5.3% |
| 59 | NOMURA ASSET MANAGEMENT INTERNATIONAL#59 · 297,819 sh | 297,819 | $9.9M | 0.01% | +63.8% |
| 60 | Ensign Peak Advisors#60 · 290,818 sh | 290,818 | $9.7M | 0.02% | +4227.0% |
| 61 | GordonMD Global Investments#61 · 289,101 sh | 289,101 | $9.7M | 4.67% | 0.0% |
| 62 | Jump Financial#62 · 286,952 sh | 286,952 | $9.6M | 0.08% | -43.1% |
| 63 | MASSACHUSETTS FINANCIAL SERVICES#63 · 272,882 sh | 272,882 | $9.1M | <0.01% | +4.8% |
| 64 | Invesco Ltd.#64 · 250,533 sh | 250,533 | $8.4M | <0.01% | -13.5% |
| 65 | Quantinno Capital Management#65 · 250,466 sh | 250,466 | $8.4M | 0.01% | +33.6% |
| 66 | KENNEDY CAPITAL MANAGEMENT#66 · 215,997 sh | 215,997 | $7.2M | 0.13% | -1.5% |
| 67 | WORLDQUANT MILLENNIUM ADVISORS#67 · 214,374 sh | 214,374 | $7.2M | 0.02% | +42.4% |
| 68 | SEI INVESTMENTS#68 · 211,833 sh | 211,833 | $7.1M | <0.01% | +130.0% |
| 69 | CITADEL ADVISORS#69 · 210,531 sh | 210,531 | $7.0M | <0.01% | -90.0% |
| 70 | Ishara Investments#70 · 205,000 sh | 205,000 | $6.8M | 5.03% | +17.6% |
| 71 | Man Group plc#71 · 195,110 sh | 195,110 | $6.5M | 0.01% | -8.6% |
| 72 | FIFTH THIRD BANCORP#72 · 193,236 sh | 193,236 | $6.5M | 0.01% | +75.2% |
| 73 | Connor, Clark & Lunn Investment Management Ltd.#73 · 191,578 sh | 191,578 | $6.4M | 0.01% | -61.8% |
| 74 | Blue Owl Capital#74 · 182,638 sh | 182,638 | $6.1M | 0.92% | -39.7% |
| 75 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#75 · 180,871 sh | 180,871 | $6.0M | <0.01% | -65.5% |
| 76 | Woodline Partners#76 · 171,805 sh | 171,805 | $5.7M | 0.02% | 0.0% |
| 77 | Atom Investors#77 · 171,771 sh | 171,771 | $5.7M | 0.51% | +83.5% |
| 78 | Swiss National Bank#78 · 167,652 sh | 167,652 | $5.6M | <0.01% | -2.0% |
| 79 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#79 · 167,226 sh | 167,226 | $5.6M | <0.01% | -25.0% |
| 80 | Ikarian Capital#80 · 165,617 sh | 165,617 | $5.5M | 0.60% | -65.7% |
| 81 | DEUTSCHE BANK AG\#81 · 164,813 sh | 164,813 | $5.5M | <0.01% | +129.3% |
| 82 | MARSHALL WACE, LLP#82 · 159,889 sh | 159,889 | $5.3M | <0.01% | +1.5% |
| 83 | SCHRODER INVESTMENT MANAGEMENT GROUP#83 · 172,086 sh | 172,086 | $5.3M | <0.01% | -3.9% |
| 84 | WELLS FARGO & COMPANY#84 · 157,643 sh | 157,643 | $5.3M | <0.01% | +129.2% |
| 85 | BOOTHBAY FUND MANAGEMENT#85 · 156,612 sh | 156,612 | $5.2M | 0.07% | +10.3% |
| 86 | MIRAE ASSET GLOBAL ETFS Ltd.#86 · 156,809 sh | 156,809 | $5.2M | <0.01% | +119.3% |
| 87 | BARCLAYS PLC#87 · 154,876 sh | 154,876 | $5.2M | <0.01% | -38.0% |
| 88 | Eversept Partners#88 · 154,130 sh | 154,130 | $5.1M | 0.27% | +146.3% |
| 89 | Ghisallo Capital Management#89 · 150,000 sh | 150,000 | $5.0M | 0.10% | New |
| 90 | Corient Private Wealth#90 · 146,493 sh | 146,493 | $4.9M | <0.01% | +7.3% |
| 91 | Mariner#91 · 146,400 sh | 146,400 | $4.9M | <0.01% | +138.8% |
| 92 | FRED ALGER MANAGEMENT#92 · 143,155 sh | 143,155 | $4.8M | 0.02% | -52.0% |
| 93 | SR ONE CAPITAL MANAGEMENT#93 · 137,753 sh | 137,753 | $4.6M | 0.44% | 0.0% |
| 94 | B Group#94 · 135,000 sh | 135,000 | $4.5M | 2.12% | 0.0% |
| 95 | PINNACLE ASSOCIATES LTD#95 · 131,104 sh | 131,104 | $4.4M | — | +27.6% |
| 96 | Caption Management#96 · 130,000 sh | 130,000 | $4.3M | 0.02% | +18.2% |
| 97 | MOORE CAPITAL MANAGEMENT#97 · 128,035 sh | 128,035 | $4.3M | 0.06% | -18.5% |
| 98 | RHUMBLINE ADVISERS#98 · 124,125 sh | 124,125 | $4.1M | <0.01% | +20.0% |
| 99 | Apollon Wealth Management#99 · 123,449 sh | 123,449 | $4.1M | — | New |
| 100 | Odyssean#100 · 122,087 sh | 122,087 | $4.1M | 0.66% | +81.1% |
Funds that sold out of RARE in Q2 2026 (44)
Held RARE at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Jones Hill Capital1,165,557 sh | 1,165,557 | $24.4M |
| Point72 Asset Management, L.P.893,295 sh | 893,295 | $18.7M |
| HRT FINANCIAL613,229 sh | 613,229 | $12.8M |
| Newtyn Management400,000 sh | 400,000 | $8.4M |
| BALYASNY ASSET MANAGEMENT L.P.384,364 sh | 384,364 | $8.1M |
| Parkman Healthcare Partners235,000 sh | 235,000 | $4.9M |
| Motley Fool Wealth Management222,981 sh | 222,981 | $4.7M |
| JANE STREET GROUP173,743 sh | 173,743 | $3.6M |
| NATIXIS81,754 sh | 81,754 | $1.7M |
| Neo Ivy Capital Management73,601 sh | 73,601 | $1.5M |
| Birchview Capital62,000 sh | 62,000 | $1.3M |
| NORDEA INVESTMENT MANAGEMENT AB57,939 sh | 57,939 | $1.2M |
| TUDOR INVESTMENT ET AL53,517 sh | 53,517 | $1.1M |
| CONGRESS ASSET MANAGEMENT44,908 sh | 44,908 | $940.8K |
| Treasurer of the State of North Carolina39,466 sh | 39,466 | $827.0K |
| TFG Asset Management GP Ltd39,473 sh | 39,473 | $827.0K |
| abrdn plc38,499 sh | 38,499 | $806.6K |
| DIADEMA PARTNERS35,144 sh | 35,144 | $736.3K |
| Bridgefront Capital35,135 sh | 35,135 | $736.1K |
| FOX RUN MANAGEMENT, L.L.C.37,136 sh | 37,136 | $716.7K |
| NOMURA30,000 sh | 30,000 | $628.5K |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO26,832 sh | 26,832 | $562.1K |
| THRIVENT FINANCIAL FOR LUTHERANS26,261 sh | 26,261 | $550.0K |
| S25,255 sh | 25,255 | $529.0K |
| AMERICAN CENTURY COMPANIES21,780 sh | 21,780 | $456.3K |
| AlphaGrep UK Ltd17,299 sh | 17,299 | $362.4K |
| TWINBEECH CAPITAL16,954 sh | 16,954 | $355.2K |
| Amundi15,166 sh | 15,166 | $317.7K |
| ADAR1 Capital Management13,400 sh | 13,400 | $280.7K |
| Toroso Investments11,563 sh | 11,563 | $242.2K |
| Caitong International Asset Management , Ltd10,794 sh | 10,794 | $226.1K |
| Persistent Asset Partners Ltd8,884 sh | 8,884 | $186.1K |
| Walleye Trading7,039 sh | 7,039 | $147.5K |
| SIMPLEX TRADING4,729 sh | 4,729 | $99.1K |
| VAN ECK ASSOCIATES4,357 sh | 4,357 | $91.0K |
| LMR Partners LLP3,451 sh | 3,451 | $72.3K |
| STRS OHIO2,205 sh | 2,205 | $46.2K |
| Root Financial Partners850 sh | 850 | $17.8K |
| Wealth Preservation Advisors145 sh | 145 | $3.0K |
| Osbon Capital Management86 sh | 86 | $1.8K |
| Golden State Wealth Management66 sh | 66 | $1.4K |
| RAFFA WEALTH MANAGEMENT21 sh | 21 | $440.00 |
| Caitlin John5 sh | 5 | $105.00 |
| Dunhill Financial1 sh | 1 | $34.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.