ProQR Therapeutics N.V. (PRQR) — Institutional Holders, Q2 2026
69 institutional investment managers reported a PRQR position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $112.0M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
PRQR in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- abrdn plcAdded · +5,615,542 sh+$10.4M
- Woodline PartnersNew · +3,277,143 sh+$6.1M
- Affinity Asset AdvisorsAdded · +3,089,658 sh+$5.7M
- HEIGHTS CAPITAL MANAGEMENTNew · +2,762,430 sh+$5.1M
- ADAGE CAPITAL PARTNERS GP, L.L.C.Added · +2,762,430 sh+$5.1M
Biggest sellers
- Sio Capital ManagementSold out · -1,954,715 sh-$3.6M
- Point72 Asset Management, L.P.Trimmed · -705,190 sh-$1.3M
- Walleye CapitalSold out · -607,529 sh-$1.1M
- NORTHERNSold out · -291,314 sh-$541.8K
- Monaco Asset Management SAMTrimmed · -174,316 sh-$324.2K
PRQR 13F holders ranked 1–69 of 69
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | ADAGE CAPITAL PARTNERS GP, L.L.C.#1 · 9,015,897 sh | 9,015,897 | $16.8M | 0.02% | +44.2% |
| 2 | abrdn plc#2 · 8,932,507 sh | 8,932,507 | $16.6M | 0.02% | +169.3% |
| 3 | Affinity Asset Advisors#3 · 5,543,936 sh | 5,543,936 | $10.3M | 0.47% | +125.9% |
| 4 | Privium Fund Management B.V.#4 · 5,520,024 sh | 5,520,024 | $10.3M | 1.89% | +1.0% |
| 5 | Ikarian Capital#5 · 3,425,930 sh | 3,425,930 | $6.4M | 0.69% | +129.6% |
| 6 | Woodline Partners#6 · 3,277,143 sh | 3,277,143 | $6.1M | 0.02% | New |
| 7 | HEIGHTS CAPITAL MANAGEMENT#7 · 2,762,430 sh | 2,762,430 | $5.1M | 1.19% | New |
| 8 | MORGAN STANLEY#8 · 1,767,215 sh | 1,767,215 | $3.3M | <0.01% | +36.0% |
| 9 | SPHERA FUNDS MANAGEMENT LTD.#9 · 1,757,458 sh | 1,757,458 | $3.3M | 0.43% | New |
| 10 | Kynam Capital Management#10 · 1,566,317 sh | 1,566,317 | $2.9M | 0.16% | 0.0% |
| 11 | DAFNA Capital Management#11 · 1,530,361 sh | 1,530,361 | $2.8M | 0.54% | -2.4% |
| 12 | Squadron Capital Management#12 · 1,511,496 sh | 1,511,496 | $2.8M | 0.87% | New |
| 13 | 683 Capital Management#13 · 1,393,067 sh | 1,393,067 | $2.6M | 0.13% | New |
| 14 | CITADEL ADVISORS#14 · 1,184,314 sh | 1,184,314 | $2.2M | <0.01% | +68.4% |
| 15 | PLATINUM INVESTMENT MANAGEMENT LTD#15 · 1,159,428 sh | 1,159,428 | $2.2M | 0.53% | -6.2% |
| 16 | TWO SIGMA INVESTMENTS#16 · 1,138,715 sh | 1,138,715 | $2.1M | <0.01% | +23.9% |
| 17 | Eversept Partners#17 · 1,022,265 sh | 1,022,265 | $1.9M | 0.10% | New |
| 18 | BOOTHBAY FUND MANAGEMENT#18 · 948,736 sh | 948,736 | $1.8M | 0.02% | +167.0% |
| 19 | DIADEMA PARTNERS#19 · 926,016 sh | 926,016 | $1.7M | 0.22% | +414.2% |
| 20 | UBS Group AG#20 · 639,243 sh | 639,243 | $1.2M | <0.01% | +109.4% |
| 21 | NOMURA ASSET MANAGEMENT INTERNATIONAL#21 · 620,000 sh | 620,000 | $1.2M | <0.01% | 0.0% |
| 22 | M28 Capital Management#22 · 599,793 sh | 599,793 | $1.1M | 2.37% | 0.0% |
| 23 | RAYMOND JAMES FINANCIAL#23 · 571,073 sh | 571,073 | $1.1M | <0.01% | +4.6% |
| 24 | JANE STREET GROUP#24 · 455,104 sh | 455,104 | $846.5K | <0.01% | +1267.1% |
| 25 | StemPoint Capital#25 · 431,054 sh | 431,054 | $801.8K | 0.14% | New |
| 26 | BNP PARIBAS FINANCIAL MARKETS#26 · 275,631 sh | 275,631 | $512.7K | <0.01% | +59.9% |
| 27 | Monaco Asset Management SAM#27 · 244,487 sh | 244,487 | $454.7K | 0.04% | -41.6% |
| 28 | Persistent Asset Partners Ltd#28 · 236,454 sh | 236,454 | $439.8K | 0.13% | +413.3% |
| 29 | Palo Alto Investors#29 · 188,807 sh | 188,807 | $351.2K | 0.05% | 0.0% |
| 30 | Burkehill Global Management#30 · 176,243 sh | 176,243 | $327.8K | 0.01% | New |
| 31 | GSA CAPITAL PARTNERS LLP#31 · 173,844 sh | 173,844 | $323.0K | 0.02% | +52.2% |
| 32 | MILLENNIUM MANAGEMENT#32 · 161,004 sh | 161,004 | $299.5K | <0.01% | -17.1% |
| 33 | FRANKLIN STREET ADVISORS#33 · 150,000 sh | 150,000 | $279.0K | — | 0.0% |
| 34 | DEUTSCHE BANK AG\#34 · 108,762 sh | 108,762 | $202.3K | <0.01% | 0.0% |
| 35 | OneDigital Investment Advisors#35 · 85,000 sh | 85,000 | $158.1K | <0.01% | 0.0% |
| 36 | Quadrature Capital Ltd#36 · 84,806 sh | 84,806 | $157.7K | <0.01% | +604.7% |
| 37 | RFG Advisory#37 · 64,000 sh | 64,000 | $119.0K | <0.01% | +236.8% |
| 38 | BANK OF AMERICA#38 · 58,040 sh | 58,040 | $108.0K | 0.00% | -68.6% |
| 39 | GEODE CAPITAL MANAGEMENT#39 · 57,997 sh | 57,997 | $107.9K | 0.00% | -31.7% |
| 40 | Point72 Asset Management, L.P.#40 · 50,652 sh | 50,652 | $94.2K | <0.01% | -93.3% |
| 41 | Keating Financial Advisory Services#41 · 47,552 sh | 47,552 | $88.4K | 0.01% | +131.4% |
| 42 | Velan Capital Investment Management#42 · 45,000 sh | 45,000 | $83.7K | 0.05% | 0.0% |
| 43 | GUGGENHEIM CAPITAL#43 · 39,954 sh | 39,954 | $74.3K | <0.01% | +44.5% |
| 44 | Steward Partners Investment Advisory#44 · 35,241 sh | 35,241 | $65.5K | <0.01% | +2610.8% |
| 45 | Axiom Investment Management#45 · 31,000 sh | 31,000 | $57.7K | 0.04% | -6.1% |
| 46 | MOODY LYNN & LIEBERSON#46 · 25,000 sh | 25,000 | $46.5K | — | 0.0% |
| 47 | Vanguard Personalized Indexing Management#47 · 22,095 sh | 22,095 | $41.1K | <0.01% | +13.8% |
| 48 | Mariner#48 · 20,169 sh | 20,169 | $37.5K | 0.00% | 0.0% |
| 49 | Verdad Advisers#49 · 19,100 sh | 19,100 | $35.5K | 0.03% | New |
| 50 | NANO CAP NEW MILLENNIUM GROWTH FUND L P#50 · 17,500 sh | 17,500 | $32.5K | 0.03% | +75.0% |
| 51 | TWO SIGMA SECURITIES#51 · 16,016 sh | 16,016 | $29.8K | <0.01% | New |
| 52 | Atom Investors#52 · 13,107 sh | 13,107 | $24.4K | <0.01% | 0.0% |
| 53 | China Universal Asset Management , Ltd.#53 · 12,500 sh | 12,500 | $23.3K | <0.01% | -37.5% |
| 54 | Virtu Financial#54 · 11,626 sh | 11,626 | $22.0K | <0.01% | New |
| 55 | WETZEL INVESTMENT ADVISORS#55 · 10,500 sh | 10,500 | $19.5K | — | New |
| 56 | ADAR1 Capital Management#56 · 10,000 sh | 10,000 | $18.6K | <0.01% | 0.0% |
| 57 | TRUIST FINANCIAL#57 · 10,000 sh | 10,000 | $18.6K | 0.00% | 0.0% |
| 58 | WELLS FARGO & COMPANY#58 · 4,000 sh | 4,000 | $7.4K | 0.00% | 0.0% |
| 59 | BlackRock#59 · 3,945 sh | 3,945 | $7.3K | 0.00% | 0.0% |
| 60 | ROYAL BANK OF CANADA#60 · 3,305 sh | 3,305 | $6.0K | 0.00% | +973.1% |
| 61 | Hilton Head Capital Partners#61 · 1,404 sh | 1,404 | $2.6K | — | 0.0% |
| 62 | Farther Finance Advisors#62 · 1,000 sh | 1,000 | $1.9K | — | 0.0% |
| 63 | PFS Partners#63 · 1,000 sh | 1,000 | $1.9K | — | 0.0% |
| 64 | SBI Securities , Ltd.#64 · 515 sh | 515 | $958.00 | — | 0.0% |
| 65 | JPMORGAN CHASE#65 · 283 sh | 283 | $518.00 | 0.00% | 0.0% |
| 66 | SIMPLEX TRADING#66 · 271 sh | 271 | $504.00 | 0.00% | -98.9% |
| 67 | TD Waterhouse Canada#67 · 40 sh | 40 | $70.00 | — | 0.0% |
| 68 | Medallion Wealth Advisors#68 · 10 sh | 10 | $19.00 | 0.00% | 0.0% |
| 69 | Caitong International Asset Management , Ltd#69 · 4 sh | 4 | $7.00 | 0.00% | -96.7% |
Funds that sold out of PRQR in Q2 2026 (12)
Held PRQR at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Sio Capital Management1,954,715 sh | 1,954,715 | $3.2M |
| Walleye Capital607,529 sh | 607,529 | $984.2K |
| NORTHERN291,314 sh | 291,314 | $471.9K |
| MARSHALL WACE, LLP115,945 sh | 115,945 | $187.8K |
| Graham Capital Management, L.P.91,553 sh | 91,553 | $148.3K |
| XTX Topco Ltd77,287 sh | 77,287 | $125.2K |
| Lynx1 Capital Management68,486 sh | 68,486 | $110.9K |
| Invesco Ltd.44,592 sh | 44,592 | $72.2K |
| Squarepoint Ops31,518 sh | 31,518 | $51.1K |
| NINE MASTS CAPITAL Ltd29,518 sh | 29,518 | $47.8K |
| GROUP ONE TRADING, L.P.18,924 sh | 18,924 | $30.7K |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP12,206 sh | 12,206 | $19.8K |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.