PLIANT THERAPEUTICS, INC. (PLRX) — Institutional Holders, Q2 2026
86 institutional investment managers reported a PLRX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $54.8M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
PLRX in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- ADAR1 Capital ManagementAdded · +2,924,598 sh+$3.3M
- Lynx1 Capital ManagementNew · +1,798,070 sh+$2.0M
- Ikarian CapitalNew · +1,000,000 sh+$1.1M
- BOOTHBAY FUND MANAGEMENTNew · +303,000 sh+$345.4K
- RENAISSANCE TECHNOLOGIESAdded · +197,032 sh+$224.6K
Biggest sellers
- Blue Owl CapitalSold out · -2,969,199 sh-$3.4M
- CITADEL ADVISORSTrimmed · -1,084,373 sh-$1.2M
- MILLENNIUM MANAGEMENTTrimmed · -621,071 sh-$708.0K
- UBS Group AGTrimmed · -486,194 sh-$554.3K
- Centiva CapitalSold out · -432,525 sh-$493.1K
PLRX 13F holders ranked 1–86 of 86
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | TANG CAPITAL MANAGEMENT#1 · 6,141,261 sh | 6,141,261 | $7.0M | 0.32% | 0.0% |
| 2 | ADAR1 Capital Management#2 · 5,509,724 sh | 5,509,724 | $6.3M | 0.29% | +113.1% |
| 3 | VANGUARD CAPITAL MANAGEMENT#3 · 2,440,351 sh | 2,440,351 | $2.8M | <0.01% | +4.2% |
| 4 | ACADIAN ASSET MANAGEMENT#4 · 2,416,508 sh | 2,416,508 | $2.7M | <0.01% | 0.0% |
| 5 | TWO SIGMA INVESTMENTS#5 · 2,262,832 sh | 2,262,832 | $2.6M | <0.01% | +0.4% |
| 6 | CITADEL ADVISORS#6 · 2,142,226 sh | 2,142,226 | $2.4M | <0.01% | -33.6% |
| 7 | RENAISSANCE TECHNOLOGIES#7 · 2,049,874 sh | 2,049,874 | $2.3M | <0.01% | +10.6% |
| 8 | Monaco Asset Management SAM#8 · 1,938,747 sh | 1,938,747 | $2.2M | 0.18% | 0.0% |
| 9 | Lynx1 Capital Management#9 · 1,798,070 sh | 1,798,070 | $2.0M | 0.40% | New |
| 10 | BML Capital Management#10 · 1,546,137 sh | 1,546,137 | $1.8M | 1.00% | 0.0% |
| 11 | Prosight Management#11 · 1,370,233 sh | 1,370,233 | $1.6M | 0.27% | -17.8% |
| 12 | Peapod Lane Capital#12 · 1,309,013 sh | 1,309,013 | $1.5M | — | +1.6% |
| 13 | Woodline Partners#13 · 1,296,534 sh | 1,296,534 | $1.5M | <0.01% | -22.2% |
| 14 | BlackRock#14 · 1,151,214 sh | 1,151,214 | $1.3M | 0.00% | +5.0% |
| 15 | Ikarian Capital#15 · 1,000,000 sh | 1,000,000 | $1.1M | 0.12% | New |
| 16 | Eversept Partners#16 · 891,425 sh | 891,425 | $1.0M | 0.05% | 0.0% |
| 17 | MARSHALL WACE, LLP#17 · 835,124 sh | 835,124 | $952.0K | <0.01% | -16.1% |
| 18 | Redmile Group#18 · 772,126 sh | 772,126 | $880.2K | 0.06% | 0.0% |
| 19 | JPMORGAN CHASE#19 · 681,647 sh | 681,647 | $783.9K | 0.00% | -20.9% |
| 20 | JACOBS LEVY EQUITY MANAGEMENT#20 · 643,120 sh | 643,120 | $733.2K | <0.01% | -10.5% |
| 21 | GEODE CAPITAL MANAGEMENT#21 · 578,577 sh | 578,577 | $660.0K | 0.00% | +38.7% |
| 22 | UBS Group AG#22 · 571,760 sh | 571,760 | $651.8K | <0.01% | -46.0% |
| 23 | MILLENNIUM MANAGEMENT#23 · 559,447 sh | 559,447 | $637.8K | <0.01% | -52.6% |
| 24 | BRIDGEWAY CAPITAL MANAGEMENT#24 · 553,630 sh | 553,630 | $631.1K | 0.01% | 0.0% |
| 25 | Connor, Clark & Lunn Investment Management Ltd.#25 · 536,081 sh | 536,081 | $611.1K | <0.01% | +3.6% |
| 26 | BESSEMER GROUP#26 · 532,079 sh | 532,079 | $606.0K | <0.01% | 0.0% |
| 27 | DAFNA Capital Management#27 · 487,000 sh | 487,000 | $555.2K | 0.11% | 0.0% |
| 28 | XTX Topco Ltd#28 · 440,844 sh | 440,844 | $502.6K | <0.01% | -12.0% |
| 29 | Laurion Capital Management#29 · 412,796 sh | 412,796 | $470.6K | 0.01% | 0.0% |
| 30 | TORNO CAPITAL#30 · 351,445 sh | 351,445 | $400.6K | 0.01% | +0.4% |
| 31 | VANGUARD FIDUCIARY#31 · 341,751 sh | 341,751 | $389.6K | <0.01% | +0.7% |
| 32 | BOOTHBAY FUND MANAGEMENT#32 · 303,000 sh | 303,000 | $345.4K | <0.01% | New |
| 33 | MORGAN STANLEY#33 · 298,976 sh | 298,976 | $340.8K | 0.00% | -40.9% |
| 34 | SEI INVESTMENTS#34 · 297,291 sh | 297,291 | $338.9K | <0.01% | 0.0% |
| 35 | Verdad Advisers#35 · 281,343 sh | 281,343 | $320.7K | 0.31% | +186.2% |
| 36 | ArrowMark Colorado#36 · 281,189 sh | 281,189 | $320.6K | 0.01% | 0.0% |
| 37 | NANO CAP NEW MILLENNIUM GROWTH FUND L P#37 · 275,000 sh | 275,000 | $313.5K | 0.24% | 0.0% |
| 38 | STATE STREET#38 · 253,418 sh | 253,418 | $288.9K | 0.00% | 0.0% |
| 39 | Stonepine Capital Management#39 · 230,538 sh | 230,538 | $262.8K | 0.12% | +2.6% |
| 40 | Rangeley Capital#40 · 225,000 sh | 225,000 | $256.5K | 0.23% | 0.0% |
| 41 | GOLDMAN SACHS GROUP#41 · 208,585 sh | 208,585 | $237.8K | 0.00% | -65.1% |
| 42 | Marquette Asset Management#42 · 174,500 sh | 174,500 | $198.9K | — | New |
| 43 | HighMark Wealth Management#43 · 166,224 sh | 166,224 | $189.5K | 0.06% | 0.0% |
| 44 | GSA CAPITAL PARTNERS LLP#44 · 162,206 sh | 162,206 | $185.0K | 0.01% | -59.7% |
| 45 | VANGUARD PORTFOLIO MANAGEMENT#45 · 153,712 sh | 153,712 | $175.2K | 0.00% | -0.1% |
| 46 | JANE STREET GROUP#46 · 129,951 sh | 129,951 | $148.1K | 0.00% | -63.6% |
| 47 | NORTHERN#47 · 125,060 sh | 125,060 | $142.6K | 0.00% | -18.9% |
| 48 | ALGERT GLOBAL#48 · 123,402 sh | 123,402 | $140.7K | <0.01% | +46.1% |
| 49 | OSAIC#49 · 114,924 sh | 114,924 | $131.0K | <0.01% | 0.0% |
| 50 | Invesco Ltd.#50 · 104,678 sh | 104,678 | $119.3K | 0.00% | -9.1% |
| 51 | Bond & Devick Financial Network#51 · 100,160 sh | 100,160 | $114.2K | — | 0.0% |
| 52 | DIMENSIONAL FUND ADVISORS#52 · 99,773 sh | 99,773 | $113.8K | 0.00% | 0.0% |
| 53 | AMERIPRISE FINANCIAL#53 · 55,129 sh | 55,129 | $62.8K | 0.00% | 0.0% |
| 54 | Squarepoint Ops#54 · 40,814 sh | 40,814 | $46.5K | <0.01% | -75.0% |
| 55 | Headlands Technologies#55 · 33,688 sh | 33,688 | $38.4K | <0.01% | New |
| 56 | Quadrature Capital Ltd#56 · 33,280 sh | 33,280 | $37.9K | <0.01% | -34.7% |
| 57 | TUDOR INVESTMENT ET AL#57 · 29,729 sh | 29,729 | $33.9K | 0.00% | 0.0% |
| 58 | FEDERATED HERMES#58 · 29,055 sh | 29,055 | $33.1K | 0.00% | -53.6% |
| 59 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO#59 · 28,500 sh | 28,500 | $32.5K | <0.01% | 0.0% |
| 60 | Spark Investment Management#60 · 22,600 sh | 22,600 | $25.8K | 0.05% | New |
| 61 | Blackstone#61 · 22,206 sh | 22,206 | $25.3K | <0.01% | 0.0% |
| 62 | Point72 Asset Management, L.P.#62 · 20,073 sh | 20,073 | $22.9K | 0.00% | -57.3% |
| 63 | Vanguard Global Advisers#63 · 19,507 sh | 19,507 | $22.2K | 0.00% | 0.0% |
| 64 | Universal- Beteiligungs- und Servicegesellschaft mbH#64 · 18,065 sh | 18,065 | $20.6K | 0.00% | 0.0% |
| 65 | Bank of New York Mellon#65 · 16,032 sh | 16,032 | $18.3K | 0.00% | +1.3% |
| 66 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#66 · 15,480 sh | 15,480 | $17.6K | 0.00% | -70.8% |
| 67 | NewEdge Advisors#67 · 15,000 sh | 15,000 | $17.1K | <0.01% | New |
| 68 | FIDUCIARY#68 · 11,620 sh | 11,620 | $13.2K | <0.01% | 0.0% |
| 69 | Qube Research & Technologies Ltd#69 · 10,033 sh | 10,033 | $11.4K | 0.00% | -8.5% |
| 70 | SIMPLEX TRADING#70 · 4,925 sh | 4,925 | $5.6K | 0.00% | -89.8% |
| 71 | ROYAL BANK OF CANADA#71 · 995 sh | 995 | $2.0K | 0.00% | -0.2% |
| 72 | Rockefeller Capital Management L.P.#72 · 660 sh | 660 | $752.00 | 0.00% | 0.0% |
| 73 | BNP PARIBAS FINANCIAL MARKETS#73 · 657 sh | 657 | $749.00 | 0.00% | 0.0% |
| 74 | HARBOUR INVESTMENTS#74 · 590 sh | 590 | $672.00 | 0.00% | +20.9% |
| 75 | BARCLAYS PLC#75 · 426 sh | 426 | $486.00 | 0.00% | +1152.9% |
| 76 | FMR#76 · 419 sh | 419 | $478.00 | 0.00% | -20.0% |
| 77 | SBI Securities , Ltd.#77 · 300 sh | 300 | $342.00 | — | 0.0% |
| 78 | Truvestments Capital#78 · 50 sh | 50 | $57.00 | 0.00% | 0.0% |
| 79 | WELLS FARGO & COMPANY#79 · 50 sh | 50 | $57.00 | 0.00% | 0.0% |
| 80 | Zurcher Kantonalbank (Zurich Cantonalbank)#80 · 36 sh | 36 | $41.00 | 0.00% | 0.0% |
| 81 | Caitong International Asset Management , Ltd#81 · 8 sh | 8 | $9.00 | 0.00% | +100.0% |
| 82 | Farther Finance Advisors#82 · 5 sh | 5 | $6.00 | — | 0.0% |
| 83 | IFG Advisory#83 · 4 sh | 4 | $5.00 | 0.00% | New |
| 84 | Global Retirement Partners#84 · 4 sh | 4 | $5.00 | 0.00% | — |
| 85 | FIFTH THIRD BANCORP#85 · 4 sh | 4 | $5.00 | 0.00% | 0.0% |
| 86 | Capital Advisors, Ltd.#86 · 31 sh | 31 | $0.00 | 0.00% | +55.0% |
Funds that sold out of PLRX in Q2 2026 (13)
Held PLRX at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Blue Owl Capital2,969,199 sh | 2,969,199 | $3.7M |
| Centiva Capital432,525 sh | 432,525 | $545.0K |
| BANK OF AMERICA352,708 sh | 352,708 | $444.4K |
| Hennion & Walsh Asset Management106,705 sh | 106,705 | $134.4K |
| Bronte Capital Management Pty Ltd.18,613 sh | 18,613 | $23.5K |
| SG Americas Securities12,604 sh | 12,604 | $16.0K |
| HRT FINANCIAL11,196 sh | 11,196 | $14.0K |
| Vanguard Personalized Indexing Management10,029 sh | 10,029 | $12.6K |
| Tower Research Capital (TRC)3,315 sh | 3,315 | $4.2K |
| RHUMBLINE ADVISERS2,379 sh | 2,379 | $3.0K |
| Owl Creek Wealth Partners2,300 sh | 2,300 | $2.9K |
| MAI Capital Management400 sh | 400 | $504.00 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT100 sh | 100 | $126.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.