OPKO HEALTH, INC. (OPK) — Institutional Holders, Q2 2026
227 institutional investment managers reported a OPK position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $366.5M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
OPK in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- HIGHBRIDGE CAPITAL MANAGEMENTNew · +3,593,925 sh+$5.4M
- STATE STREETAdded · +807,693 sh+$1.2M
- MORGAN STANLEYAdded · +778,940 sh+$1.2M
- BlackRockAdded · +746,670 sh+$1.1M
- AQR CAPITAL MANAGEMENTAdded · +475,809 sh+$713.7K
Biggest sellers
- UBS Group AGTrimmed · -1,065,148 sh-$1.6M
- JANE STREET GROUPTrimmed · -884,921 sh-$1.3M
- Tejara Capital LtdSold out · -877,941 sh-$1.3M
- GSA CAPITAL PARTNERS LLPSold out · -663,704 sh-$995.6K
- CITADEL ADVISORSTrimmed · -658,625 sh-$987.9K
OPK 13F holders ranked 1–100 of 227
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | Rubric Capital Management#1 · 49,041,243 sh | 49,041,243 | $73.6M | 0.67% | 0.0% |
| 2 | BlackRock#2 · 36,978,893 sh | 36,978,893 | $55.5M | <0.01% | +2.1% |
| 3 | VANGUARD CAPITAL MANAGEMENT#3 · 14,968,930 sh | 14,968,930 | $22.5M | <0.01% | +3.2% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT#4 · 14,934,924 sh | 14,934,924 | $22.4M | <0.01% | +1.1% |
| 5 | Whitefort Capital Management#5 · 13,861,412 sh | 13,861,412 | $20.8M | 5.14% | +1.9% |
| 6 | WOLVERINE ASSET MANAGEMENT#6 · 13,785,000 sh | 13,785,000 | $20.4M | 0.18% | +6.4% |
| 7 | GEODE CAPITAL MANAGEMENT#7 · 11,581,027 sh | 11,581,027 | $17.4M | <0.01% | +2.5% |
| 8 | STATE STREET#8 · 10,309,070 sh | 10,309,070 | $15.5M | <0.01% | +8.5% |
| 9 | PenderFund Capital Management Ltd.#9 · 8,491,000 sh | 8,491,000 | $12.8M | 1.64% | +16.1% |
| 10 | GOLDMAN SACHS GROUP#10 · 7,035,492 sh | 7,035,492 | $10.6M | <0.01% | -8.3% |
| 11 | ZAZOVE ASSOCIATES#11 · 6,003,000 sh | 6,003,000 | $9.1M | 0.74% | -1.1% |
| 12 | UBS Group AG#12 · 5,006,284 sh | 5,006,284 | $7.5M | <0.01% | -17.5% |
| 13 | NORTHERN#13 · 3,756,163 sh | 3,756,163 | $5.6M | <0.01% | +3.8% |
| 14 | HIGHBRIDGE CAPITAL MANAGEMENT#14 · 3,593,925 sh | 3,593,925 | $5.4M | 0.13% | New |
| 15 | CHARLES SCHWAB INVESTMENT MANAGEMENT#15 · 3,596,980 sh | 3,596,980 | $5.4M | <0.01% | +0.6% |
| 16 | VANGUARD FIDUCIARY#16 · 2,706,235 sh | 2,706,235 | $4.1M | <0.01% | -1.3% |
| 17 | LINDEN ADVISORS#17 · 2,235,000 sh | 2,235,000 | $3.4M | 0.02% | 0.0% |
| 18 | AWM Investment Company#18 · 2,110,000 sh | 2,110,000 | $3.2M | 0.27% | +0.5% |
| 19 | MORGAN STANLEY#19 · 1,975,027 sh | 1,975,027 | $3.0M | <0.01% | +65.1% |
| 20 | CITADEL ADVISORS#20 · 1,420,922 sh | 1,420,922 | $2.1M | <0.01% | -31.7% |
| 21 | FMR#21 · 1,430,336 sh | 1,430,336 | $2.1M | <0.01% | +1.0% |
| 22 | WASHINGTON GROWTH STRATEGIES#22 · 1,356,124 sh | 1,356,124 | $2.0M | — | 0.0% |
| 23 | Bank of New York Mellon#23 · 1,329,974 sh | 1,329,974 | $2.0M | <0.01% | +3.9% |
| 24 | DIMENSIONAL FUND ADVISORS#24 · 1,267,741 sh | 1,267,741 | $1.9M | <0.01% | -18.7% |
| 25 | Y.D. More Investments Ltd#25 · 1,257,568 sh | 1,257,568 | $1.9M | 0.06% | -3.2% |
| 26 | AQR CAPITAL MANAGEMENT#26 · 1,239,399 sh | 1,239,399 | $1.9M | <0.01% | +62.3% |
| 27 | OP Asset Management Ltd#27 · 1,159,647 sh | 1,159,647 | $1.7M | 0.02% | +5.2% |
| 28 | VOYA INVESTMENT MANAGEMENT#28 · 1,094,111 sh | 1,094,111 | $1.6M | <0.01% | -5.8% |
| 29 | Clearstead Advisors#29 · 883,288 sh | 883,288 | $1.3M | 0.01% | -0.1% |
| 30 | Nuveen#30 · 863,035 sh | 863,035 | $1.3M | <0.01% | +1.9% |
| 31 | BANK OF AMERICA#31 · 795,716 sh | 795,716 | $1.2M | <0.01% | -30.3% |
| 32 | Swiss National Bank#32 · 761,455 sh | 761,455 | $1.1M | <0.01% | -10.0% |
| 33 | JPMORGAN CHASE#33 · 862,305 sh | 862,305 | $1.1M | <0.01% | -30.6% |
| 34 | Invesco Ltd.#34 · 685,076 sh | 685,076 | $1.0M | <0.01% | -13.6% |
| 35 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#35 · 623,561 sh | 623,561 | $935.3K | <0.01% | +59.3% |
| 36 | PFG Investments#36 · 610,491 sh | 610,491 | $915.7K | 0.04% | -45.1% |
| 37 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#37 · 574,107 sh | 574,107 | $861.2K | <0.01% | -14.9% |
| 38 | Kovack Advisors#38 · 536,202 sh | 536,202 | $804.3K | 0.04% | +16.6% |
| 39 | RHUMBLINE ADVISERS#39 · 498,861 sh | 498,861 | $748.3K | <0.01% | +0.3% |
| 40 | PRICE T ROWE ASSOCIATES#40 · 455,748 sh | 455,748 | $684.0K | <0.01% | +12.6% |
| 41 | VAN ECK ASSOCIATES#41 · 438,645 sh | 438,645 | $658.0K | <0.01% | +174.0% |
| 42 | COMMONWEALTH EQUITY SERVICES#42 · 431,894 sh | 431,894 | $647.8K | <0.01% | +0.2% |
| 43 | Connor, Clark & Lunn Investment Management Ltd.#43 · 412,051 sh | 412,051 | $618.1K | <0.01% | -21.2% |
| 44 | DEUTSCHE BANK AG\#44 · 398,603 sh | 398,603 | $597.9K | <0.01% | +7.5% |
| 45 | ALGERT GLOBAL#45 · 397,030 sh | 397,030 | $595.5K | <0.01% | New |
| 46 | WELLS FARGO & COMPANY#46 · 354,039 sh | 354,039 | $531.1K | <0.01% | +117.7% |
| 47 | Legal & General Group Plc#47 · 346,787 sh | 346,787 | $520.2K | <0.01% | +1.0% |
| 48 | ALLIANCEBERNSTEIN L.P.#48 · 442,680 sh | 442,680 | $504.7K | <0.01% | +4.6% |
| 49 | VANGUARD ASSET MANAGEMENT, Ltd#49 · 294,013 sh | 294,013 | $441.0K | <0.01% | 0.0% |
| 50 | ROYAL BANK OF CANADA#50 · 289,812 sh | 289,812 | $435.0K | <0.01% | +31.7% |
| 51 | XTX Topco Ltd#51 · 286,173 sh | 286,173 | $429.3K | <0.01% | -33.6% |
| 52 | Assenagon Asset Management S.A.#52 · 285,339 sh | 285,339 | $425.5K | — | -56.2% |
| 53 | Creative Planning#53 · 246,065 sh | 246,065 | $369.1K | <0.01% | +39.0% |
| 54 | TUDOR INVESTMENT ET AL#54 · 244,821 sh | 244,821 | $367.2K | <0.01% | 0.0% |
| 55 | JANE STREET GROUP#55 · 229,454 sh | 229,454 | $344.2K | 0.00% | -79.4% |
| 56 | MetLife Investment Management#56 · 226,799 sh | 226,799 | $340.2K | <0.01% | +10.8% |
| 57 | Russell Investments Group, Ltd.#57 · 215,820 sh | 215,820 | $323.7K | <0.01% | +578.3% |
| 58 | Jupiter Topco#58 · 206,314 sh | 206,314 | $310.5K | <0.01% | — |
| 59 | CITIGROUP#59 · 199,824 sh | 199,824 | $299.7K | <0.01% | +493.4% |
| 60 | HSBC PLC#60 · 199,966 sh | 199,966 | $298.9K | <0.01% | -16.1% |
| 61 | MIRAE ASSET GLOBAL ETFS Ltd.#61 · 185,564 sh | 185,564 | $278.3K | <0.01% | -6.2% |
| 62 | Vanguard Global Advisers#62 · 181,766 sh | 181,766 | $272.6K | <0.01% | 0.0% |
| 63 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM#63 · 176,260 sh | 176,260 | $264.4K | <0.01% | 0.0% |
| 64 | TWO SIGMA INVESTMENTS#64 · 175,801 sh | 175,801 | $263.7K | <0.01% | +3.4% |
| 65 | GAMCO INVESTORS, ET AL#65 · 175,000 sh | 175,000 | $262.5K | <0.01% | 0.0% |
| 66 | GABELLI FUNDS#66 · 170,000 sh | 170,000 | $255.0K | <0.01% | 0.0% |
| 67 | FIFTH THIRD BANCORP#67 · 170,000 sh | 170,000 | $255.0K | <0.01% | +32.0% |
| 68 | IEQ CAPITAL#68 · 169,425 sh | 169,425 | $254.1K | <0.01% | +81.7% |
| 69 | 360 Financial#69 · 150,300 sh | 150,300 | $225.4K | 0.06% | +54.5% |
| 70 | Point72 Asset Management, L.P.#70 · 145,234 sh | 145,234 | $217.9K | <0.01% | +55.6% |
| 71 | Teton Advisors#71 · 140,000 sh | 140,000 | $210.0K | 0.12% | 0.0% |
| 72 | Police & Firemen's Retirement System of New Jersey#72 · 132,463 sh | 132,463 | $198.7K | <0.01% | +29.4% |
| 73 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#73 · 119,132 sh | 119,132 | $178.7K | <0.01% | -2.5% |
| 74 | HIGHLINE WEALTH PARTNERS#74 · 116,680 sh | 116,680 | $175.0K | — | 0.0% |
| 75 | State of Wyoming#75 · 116,489 sh | 116,489 | $174.7K | 0.02% | -30.3% |
| 76 | NEW YORK STATE COMMON RETIREMENT FUND#76 · 114,301 sh | 114,301 | $171.5K | <0.01% | 0.0% |
| 77 | SG Americas Securities#77 · 113,848 sh | 113,848 | $171.0K | <0.01% | +29.6% |
| 78 | GLENMEDE NA#78 · 112,750 sh | 112,750 | $169.1K | <0.01% | 0.0% |
| 79 | Vanguard Investments Australia, Ltd.#79 · 110,958 sh | 110,958 | $166.4K | <0.01% | 0.0% |
| 80 | Headlands Technologies#80 · 107,989 sh | 107,989 | $162.0K | 0.02% | +91.2% |
| 81 | Arizona State Retirement System#81 · 104,725 sh | 104,725 | $157.1K | <0.01% | -9.7% |
| 82 | BARCLAYS PLC#82 · 99,596 sh | 99,596 | $149.4K | 0.00% | -28.0% |
| 83 | AMERIPRISE FINANCIAL#83 · 94,061 sh | 94,061 | $141.1K | 0.00% | -2.8% |
| 84 | SRS Capital Advisors#84 · 93,616 sh | 93,616 | $140.4K | <0.01% | New |
| 85 | Cerity Partners#85 · 91,099 sh | 91,099 | $136.7K | <0.01% | +288.1% |
| 86 | KLP KAPITALFORVALTNING AS#86 · 90,700 sh | 90,700 | $136.1K | <0.01% | 0.0% |
| 87 | RPg Family Wealth Advisory#87 · 88,619 sh | 88,619 | $132.9K | 0.02% | 0.0% |
| 88 | INTECH INVESTMENT MANAGEMENT#88 · 85,883 sh | 85,883 | $128.8K | <0.01% | -31.7% |
| 89 | Allied Private Wealth#89 · 91,137 sh | 91,137 | $128.5K | 0.08% | — |
| 90 | Cambridge Investment Research Advisors#90 · 83,675 sh | 83,675 | $126.0K | <0.01% | -7.3% |
| 91 | MERCER GLOBAL ADVISORS#91 · 76,808 sh | 76,808 | $115.2K | <0.01% | +45.4% |
| 92 | WEALTH ENHANCEMENT ADVISORY SERVICES#92 · 83,994 sh | 83,994 | $113.4K | — | +34.7% |
| 93 | MILLENNIUM MANAGEMENT#93 · 72,301 sh | 72,301 | $108.5K | 0.00% | New |
| 94 | OSAIC#94 · 69,567 sh | 69,567 | $104.3K | <0.01% | +45.9% |
| 95 | PRUDENTIAL FINANCIAL#95 · 68,976 sh | 68,976 | $103.5K | <0.01% | +5.2% |
| 96 | Cascade Financial Partners#96 · 66,490 sh | 66,490 | $99.7K | <0.01% | 0.0% |
| 97 | Pictet Asset Management Holding SA#97 · 65,495 sh | 65,495 | $98.2K | <0.01% | 0.0% |
| 98 | CAPTRUST FINANCIAL ADVISORS#98 · 63,704 sh | 63,704 | $95.6K | <0.01% | +58.1% |
| 99 | PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO#99 · 61,502 sh | 61,502 | $92.0K | <0.01% | 0.0% |
| 100 | Cetera Investment Advisers#100 · 60,947 sh | 60,947 | $91.4K | <0.01% | +2.7% |
Funds that sold out of OPK in Q2 2026 (30)
Held OPK at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Tejara Capital Ltd877,941 sh | 877,941 | $1.0M |
| GSA CAPITAL PARTNERS LLP663,704 sh | 663,704 | $757.0K |
| FIRST ADVISORS500,273 sh | 500,273 | $570.3K |
| Qube Research & Technologies Ltd404,358 sh | 404,358 | $461.0K |
| EntryPoint Capital342,171 sh | 342,171 | $390.1K |
| RENAISSANCE TECHNOLOGIES109,543 sh | 109,543 | $124.9K |
| HRT FINANCIAL90,759 sh | 90,759 | $103.0K |
| Quadrature Capital Ltd88,937 sh | 88,937 | $101.4K |
| Brevan Howard Capital Management45,919 sh | 45,919 | $52.3K |
| LGL PARTNERS44,507 sh | 44,507 | $50.7K |
| QUADRANT CAPITAL GROUP544 sh | 544 | $49.3K |
| Abel Hall33,271 sh | 33,271 | $37.9K |
| MIRABELLA FINANCIAL SERVICES LLP24,906 sh | 24,906 | $28.4K |
| ZACKS INVESTMENT MANAGEMENT24,665 sh | 24,665 | $28.1K |
| CAPITAL ADVISORS20,000 sh | 20,000 | $22.8K |
| PRINCIPAL FINANCIAL GROUP17,740 sh | 17,740 | $20.2K |
| CIBC WORLD MARKET17,228 sh | 17,228 | $19.6K |
| Blueshift Asset Management17,036 sh | 17,036 | $19.4K |
| Sequoia Financial Advisors16,264 sh | 16,264 | $18.5K |
| STIFEL FINANCIAL15,549 sh | 15,549 | $17.7K |
| MOODY NATIONAL BANK DIVISION13,554 sh | 13,554 | $15.5K |
| IMC-Chicago10,874 sh | 10,874 | $12.4K |
| Frec Markets10,542 sh | 10,542 | $12.0K |
| Sanibel Captiva Company10,000 sh | 10,000 | $11.4K |
| Aquatic Capital Management4,166 sh | 4,166 | $4.7K |
| Aster Capital Management (DIFC) Ltd806 sh | 806 | $1.3K |
| Root Financial Partners100 sh | 100 | $114.00 |
| MAI Capital Management43 sh | 43 | $50.00 |
| Darwin Wealth Management5 sh | 5 | $5.00 |
| Wilkerson Advisory Group4 sh | 4 | $5.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.