LYRA is the ticker symbol for Lyra Therapeutics, Inc., a publicly traded Healthcare sector company listed on Nasdaq. 13F Pro tracks LYRA with AI-powered analysis, a 32-signal quality score, SEC EDGAR financials, insider transactions, and institutional 13F holdings — all sourced directly from public SEC filings.

Is LYRA a good stock to buy?

LYRA is tracked on 13F Pro with SEC EDGAR data, but is not currently included in our 32-signal AI quality ranking. The full company profile with financials and AI insights is at https://13fpro.ai/company/LYRA.

Where does 13F Pro source LYRA data?

All Lyra Therapeutics, Inc. fundamentals and ownership data come directly from SEC EDGAR. Lyra Therapeutics, Inc. files with the SEC under CIK 1327273. 13F Pro ingests XBRL financial facts from 10-K and 10-Q filings, Form 13F-HR institutional holdings, and Form 4 insider transactions, with no third-party rewrites or estimates.

Lyra Therapeutics, Inc.(LYRA)— Stock Profile, AI Score & Financials

Healthcare · Nasdaq · AI-powered stock analysis, 32-signal quality score, SEC EDGAR financials, and institutional holdings. Updated 2025-12-31.

Lyra Therapeutics, Inc. (LYRA) stock profile, AI quality score, and SEC EDGAR financial data, a Healthcare sector company. LYRA is not currently included in 13F Pro's AI-ranked quality universe — below the main board's size threshold of $25m annual revenue or $100m total assets. this company reported $1.6m in revenue and is scored on the micro-cap board instead. Based on the latest XBRL financial filings (Q4 2025), Lyra Therapeutics, Inc. reports quarterly revenue of $7.0K, net income of $-7.0M, free cash flow of $-6.2M. Top institutional holders of LYRA by reported 13-F value include SABBY MANAGEMENT, Ikarian Capital, DRW Securities, based on the most recent SEC filings. LYRA trades on the Nasdaq exchange and files with the SEC under CIK 1327273. 13F Pro's AI research platform runs 10 specialized AI analysts — value, growth, momentum, macro, and activist specialists — that debate LYRA daily and publish AI-generated analysis with cited SEC sources. The platform aggregates historical XBRL financial facts, 10-Q and 10-K filings, insider Form 4 transactions, and institutional 13-F holdings for Lyra Therapeutics, Inc. directly from SEC EDGAR.

Revenue

$7.0K

Net Income

$-7.0M

Free Cash Flow

$-6.2M

LYRA key financials by period

Lyra Therapeutics, Inc. reported revenue, net income and margins by fiscal period, from SEC filings.
Period	Form	Revenue	Net income	Operating margin
FY 2025	10-K	$398.0K	$-28.9M	—
FY 2024	10-K	$1.5M	$-93.4M	—
FY 2023	10-K	$1.6M	$-62.7M	—
FY 2022	10-K	$1.4M	$-55.3M	—
FY 2021	10-K	$285.0K	$-43.5M	—

Institutions holding LYRA

Institutional investors reporting a position in Lyra Therapeutics, Inc. on SEC Form 13F.
Institution	Shares	Value	Reported
SABBY MANAGEMENT	175,158	$539.5K	2025-12-31
Ikarian Capital	21,161	$65.2K	2025-12-31
DRW Securities	16,812	$51.8K	2025-12-31
GEODE CAPITAL MANAGEMENT	12,249	$37.7K	2025-12-31
Artia Global Partners	8,756	$27.0K	2025-12-31
BlackRock	2,394	$7.4K	2025-12-31
Tower Research Capital (TRC)	2,191	$6.7K	2025-12-31
ROYAL BANK OF CANADA	1,953	$6.0K	2025-12-31
UBS Group AG	675	$2.1K	2025-12-31
EverSource Wealth Advisors	338	$1.0K	2025-12-31

SEC EDGAR: CIK 1327273 →

Lyra Therapeutics, Inc.

LYRA

NasdaqSmall CapHealthcare

13F Pro Quality Score

Not in ranked universe

Below size threshold

Below the main board's size threshold of $25M annual revenue or $100M total assets. This company reported $1.6M in revenue and is scored on the micro-cap board instead.

Financial data, filings, and institutional holdings below are still tracked in full — only the proprietary quality composite is unavailable for this name.