LEXICON PHARMACEUTICALS, INC. (LXRX) — Institutional Holders, Q2 2026 (page 2)

150 institutional investment managers reported a LXRX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $875.0M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 101 to 150. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

LXRX 13F holders ranked 101–150 of 150

Institutional investors reporting a position in LEXICON PHARMACEUTICALS, INC. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
InstitutionValueQoQ
SBI Securities , Ltd.#101 · 19,205 sh$46.1K+370.6%
PRINCIPAL FINANCIAL GROUP#102 · 19,034 sh$45.7KNew
CREDIT AGRICOLE S A#103 · 18,975 sh$45.5K0.0%
CAPTRUST FINANCIAL ADVISORS#104 · 15,321 sh$36.8K-0.8%
Callan Family Office#105 · 14,090 sh$33.8K0.0%
TRUIST FINANCIAL#106 · 14,000 sh$33.6K0.0%
CIBC Bancorp USA#107 · 13,740 sh$33.0K-99.2%
Gotham Asset Management#108 · 13,627 sh$32.7KNew
CIBC Asset Management#109 · 13,102 sh$31.4K-66.8%
ROYAL BANK OF CANADA#110 · 12,650 sh$30.0K+715.6%
HBK Sorce Advisory#111 · 11,786 sh$28.9K0.0%
Squarepoint Ops#112 · 11,741 sh$28.2KNew
Apollon Wealth Management#113 · 11,378 sh$27.3KNew
Mariner#114 · 11,239 sh$27.0K+1.5%
WEALTH ENHANCEMENT ADVISORY SERVICES#115 · 12,139 sh$26.9K-2.0%
Perennial Investment Advisors#116 · 10,990 sh$26.4K0.0%
Cetera Investment Advisers#117 · 10,524 sh$25.3K-16.7%
Berger Financial Group#118 · 10,000 sh$24.0K0.0%
NBT BANK N A#119 · 10,000 sh$24.0K0.0%
SIMPLEX TRADING#120 · 8,540 sh$20.5KNew
NISA INVESTMENT ADVISORS#121 · 2,592 sh$6.2K0.0%
Integrated Wealth Concepts#122 · 2,077 sh$5.0KNew
PNC FINANCIAL SERVICES GROUP#123 · 1,461 sh$3.5K0.0%
Physician Wealth Advisors#124 · 1,412 sh$3.4K0.0%
Rialto Wealth Management#125 · 1,313 sh$3.2K0.0%
Global Retirement Partners#126 · 1,000 sh$2.4K—
Cassaday & Wealth Management#127 · 1,000 sh$2.4K0.0%
MassMutual Private Wealth & , FSB#128 · 957 sh$2.3KNew
Sterling Capital Management#129 · 874 sh$2.1KNew
Avion Wealth#130 · 1,115 sh$2.0K-16.4%
Aster Capital Management (DIFC) Ltd#131 · 743 sh$1.8KNew
Fortitude Family Office#132 · 706 sh$1.7K0.0%
Basecamp Wealth Advisors#133 · 691 sh$1.7K0.0%
NORTHWESTERN MUTUAL WEALTH MANAGEMENT#134 · 500 sh$1.2K-0.6%
Steward Partners Investment Advisory#135 · 400 sh$960.00-20.0%
JONES FINANCIAL COMPANIES LLLP#136 · 356 sh$908.000.0%
Rockefeller Capital Management L.P.#137 · 300 sh$720.00-10.4%
Allworth Financial#138 · 263 sh$632.00New
Parallel Advisors#139 · 247 sh$593.000.0%
OSAIC#140 · 163 sh$390.00-75.4%
Caitong International Asset Management , Ltd#141 · 157 sh$377.00-55.5%
SYNTAX RESEARCH#142 · 142 sh$341.000.0%
Larson Financial Group#143 · 100 sh$240.000.0%
Clearstead Advisors#144 · 100 sh$240.00New
SRS Capital Advisors#145 · 41 sh$98.000.0%
HM PAYSON#146 · 37 sh$89.000.0%
Blume Capital Management#147 · 5 sh$12.00New
Farther Finance Advisors#148 · 2 sh$5.00-99.2%
Covestor Ltd#149 · 81 sh$0.000.0%
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM#150 · 3,427 sh—New

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.