Jade Biosciences, Inc. (JBIO) — Institutional Holders, Q2 2026
155 institutional investment managers reported a JBIO position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $1.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
JBIO in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- Paradigm Biocapital AdvisorsNew · +2,857,405 sh+$63.5M
- FRANKLIN RESOURCESNew · +2,792,080 sh+$62.0M
- FMRAdded · +2,041,454 sh+$45.4M
- ADAGE CAPITAL PARTNERS GP, L.L.C.New · +1,910,812 sh+$42.5M
- Polar Capital PlcNew · +1,846,982 sh+$41.0M
Biggest sellers
- GREAT POINT PARTNERSSold out · -964,462 sh-$21.4M
- DRIEHAUS CAPITAL MANAGEMENTSold out · -635,498 sh-$14.1M
- RTW INVESTMENTSSold out · -573,205 sh-$12.7M
- Versant Venture ManagementTrimmed · -534,037 sh-$11.9M
- Bellevue Group AGTrimmed · -443,506 sh-$9.9M
JBIO 13F holders ranked 1–100 of 155
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | FMR#1 · 9,126,877 sh | 9,126,877 | $202.8M | <0.01% | +28.8% |
| 2 | Jupiter Topco#2 · 6,273,262 sh | 6,273,262 | $139.4M | 0.06% | — |
| 3 | Fairmount Funds Management#3 · 4,553,494 sh | 4,553,494 | $101.2M | 6.69% | 0.0% |
| 4 | RA CAPITAL MANAGEMENT, L.P.#4 · 3,671,083 sh | 3,671,083 | $81.6M | 0.71% | 0.0% |
| 5 | VR Adviser#5 · 3,220,364 sh | 3,220,364 | $71.6M | 2.17% | 0.0% |
| 6 | Bellevue Group AG#6 · 3,057,996 sh | 3,057,996 | $67.9M | 1.43% | -12.7% |
| 7 | Paradigm Biocapital Advisors#7 · 2,857,405 sh | 2,857,405 | $63.5M | 1.19% | New |
| 8 | BlackRock#8 · 2,801,451 sh | 2,801,451 | $62.2M | <0.01% | +21.1% |
| 9 | FRANKLIN RESOURCES#9 · 2,792,080 sh | 2,792,080 | $62.0M | 0.01% | New |
| 10 | STATE STREET#10 · 2,335,285 sh | 2,335,285 | $51.9M | <0.01% | +256.2% |
| 11 | VANGUARD CAPITAL MANAGEMENT#11 · 2,244,773 sh | 2,244,773 | $49.9M | <0.01% | +24.9% |
| 12 | ADAGE CAPITAL PARTNERS GP, L.L.C.#12 · 1,910,812 sh | 1,910,812 | $42.5M | 0.06% | New |
| 13 | Polar Capital Plc#13 · 1,846,982 sh | 1,846,982 | $41.0M | 0.10% | New |
| 14 | Avidity Partners Management#14 · 1,700,708 sh | 1,700,708 | $37.8M | 6.05% | +21.4% |
| 15 | Remedium Capital Partners#15 · 1,577,750 sh | 1,577,750 | $35.1M | 7.76% | 0.0% |
| 16 | Soleus Capital Management, L.P.#16 · 1,550,690 sh | 1,550,690 | $34.5M | 1.19% | +94.6% |
| 17 | JPMORGAN CHASE#17 · 1,475,079 sh | 1,475,079 | $32.6M | <0.01% | +9198.9% |
| 18 | BAKER BROS. ADVISORS#18 · 1,230,426 sh | 1,230,426 | $27.3M | 0.14% | -25.0% |
| 19 | Logos Global Management#19 · 1,125,000 sh | 1,125,000 | $25.0M | 1.08% | +181.2% |
| 20 | Versant Venture Management#20 · 991,783 sh | 991,783 | $22.0M | 13.55% | -35.0% |
| 21 | ACORN CAPITAL ADVISORS#21 · 986,760 sh | 986,760 | $21.9M | 5.98% | +25.4% |
| 22 | GEODE CAPITAL MANAGEMENT#22 · 985,178 sh | 985,178 | $21.9M | <0.01% | +19.8% |
| 23 | CITADEL ADVISORS#23 · 929,407 sh | 929,407 | $20.7M | <0.01% | +577.3% |
| 24 | Foresite Capital Management VI#24 · 886,667 sh | 886,667 | $19.7M | 3.07% | +177.1% |
| 25 | BALYASNY ASSET MANAGEMENT L.P.#25 · 878,726 sh | 878,726 | $19.5M | 0.02% | +118.3% |
| 26 | Affinity Asset Advisors#26 · 840,350 sh | 840,350 | $18.7M | 0.84% | +31.3% |
| 27 | Samsara BioCapital#27 · 736,237 sh | 736,237 | $16.4M | 1.34% | -24.0% |
| 28 | GOLDMAN SACHS GROUP#28 · 735,224 sh | 735,224 | $16.3M | <0.01% | +380.4% |
| 29 | Pictet Asset Management Holding SA#29 · 733,768 sh | 733,768 | $16.3M | 0.02% | New |
| 30 | abrdn plc#30 · 621,108 sh | 621,108 | $13.8M | 0.02% | -28.4% |
| 31 | MARSHALL WACE, LLP#31 · 585,761 sh | 585,761 | $13.0M | 0.01% | -38.0% |
| 32 | BANK OF AMERICA#32 · 486,955 sh | 486,955 | $10.8M | <0.01% | +1161.6% |
| 33 | VANGUARD PORTFOLIO MANAGEMENT#33 · 461,528 sh | 461,528 | $10.3M | <0.01% | +118.4% |
| 34 | Blackstone#34 · 435,320 sh | 435,320 | $9.7M | 0.02% | New |
| 35 | Ikarian Capital#35 · 427,349 sh | 427,349 | $9.5M | 1.02% | -16.6% |
| 36 | Walleye Capital#36 · 365,272 sh | 365,272 | $8.1M | 0.03% | New |
| 37 | MILLENNIUM MANAGEMENT#37 · 314,548 sh | 314,548 | $7.0M | <0.01% | +96.5% |
| 38 | VANGUARD FIDUCIARY#38 · 304,867 sh | 304,867 | $6.8M | <0.01% | +38.9% |
| 39 | NORTHERN#39 · 295,081 sh | 295,081 | $6.6M | <0.01% | +22.0% |
| 40 | LORD, ABBETT#40 · 226,606 sh | 226,606 | $5.0M | 0.01% | New |
| 41 | Connor, Clark & Lunn Investment Management Ltd.#41 · 217,157 sh | 217,157 | $4.8M | <0.01% | +28.5% |
| 42 | BNP PARIBAS FINANCIAL MARKETS#42 · 199,429 sh | 199,429 | $4.4M | <0.01% | +596.7% |
| 43 | Jump Financial#43 · 172,747 sh | 172,747 | $3.8M | 0.03% | +1364.0% |
| 44 | Point72 Asset Management, L.P.#44 · 167,204 sh | 167,204 | $3.7M | <0.01% | -36.7% |
| 45 | Russell Investments Group, Ltd.#45 · 163,084 sh | 163,084 | $3.6M | <0.01% | +51.6% |
| 46 | Opaleye Management#46 · 145,000 sh | 145,000 | $3.2M | 0.29% | -66.1% |
| 47 | SCHRODER INVESTMENT MANAGEMENT GROUP#47 · 140,886 sh | 140,886 | $3.1M | <0.01% | +258.7% |
| 48 | UBS Group AG#48 · 127,577 sh | 127,577 | $2.8M | <0.01% | +96.2% |
| 49 | MORGAN STANLEY#49 · 124,513 sh | 124,513 | $2.8M | <0.01% | +146.1% |
| 50 | Quantinno Capital Management#50 · 114,716 sh | 114,716 | $2.5M | <0.01% | +275.5% |
| 51 | BOOTHBAY FUND MANAGEMENT#51 · 112,703 sh | 112,703 | $2.5M | 0.03% | -19.5% |
| 52 | Sofinnova Ventures#52 · 107,391 sh | 107,391 | $2.4M | 0.12% | 0.0% |
| 53 | AMERIPRISE FINANCIAL#53 · 107,053 sh | 107,053 | $2.4M | <0.01% | New |
| 54 | Woodline Partners#54 · 100,269 sh | 100,269 | $2.2M | <0.01% | New |
| 55 | SEVEN GRAND MANAGERS#55 · 100,000 sh | 100,000 | $2.2M | 0.09% | New |
| 56 | CHARLES SCHWAB INVESTMENT MANAGEMENT#56 · 99,977 sh | 99,977 | $2.2M | <0.01% | +9.1% |
| 57 | WELLINGTON MANAGEMENT GROUP LLP#57 · 90,396 sh | 90,396 | $2.0M | <0.01% | -30.0% |
| 58 | HealthInvest Partners AB#58 · 88,556 sh | 88,556 | $2.0M | 0.53% | New |
| 59 | Bank of New York Mellon#59 · 85,343 sh | 85,343 | $1.9M | <0.01% | -5.1% |
| 60 | Swiss National Bank#60 · 83,300 sh | 83,300 | $1.9M | <0.01% | New |
| 61 | RAYMOND JAMES FINANCIAL#61 · 78,723 sh | 78,723 | $1.7M | <0.01% | New |
| 62 | Longaeva Partners L.P.#62 · 78,501 sh | 78,501 | $1.7M | 0.04% | New |
| 63 | Nuveen#63 · 76,047 sh | 76,047 | $1.7M | <0.01% | +64.5% |
| 64 | RENAISSANCE TECHNOLOGIES#64 · 73,591 sh | 73,591 | $1.6M | <0.01% | -45.5% |
| 65 | AMERICAN CENTURY COMPANIES#65 · 68,980 sh | 68,980 | $1.5M | <0.01% | +106.7% |
| 66 | Trexquant Investment#66 · 68,316 sh | 68,316 | $1.5M | <0.01% | +143.1% |
| 67 | Harvest Investment Services#67 · 62,983 sh | 62,983 | $1.4M | 0.22% | New |
| 68 | Corient Private Wealth#68 · 61,530 sh | 61,530 | $1.4M | <0.01% | New |
| 69 | XTX Topco Ltd#69 · 59,093 sh | 59,093 | $1.3M | 0.02% | -24.3% |
| 70 | Verdad Advisers#70 · 56,384 sh | 56,384 | $1.3M | 1.20% | New |
| 71 | Squarepoint Ops#71 · 54,456 sh | 54,456 | $1.2M | <0.01% | +22.0% |
| 72 | CITIGROUP#72 · 54,380 sh | 54,380 | $1.2M | <0.01% | +614.0% |
| 73 | D. E. Shaw#73 · 51,494 sh | 51,494 | $1.1M | <0.01% | New |
| 74 | Maven Securities LTD#74 · 50,000 sh | 50,000 | $1.1M | 0.02% | New |
| 75 | VOLORIDGE INVESTMENT MANAGEMENT#75 · 48,374 sh | 48,374 | $1.1M | <0.01% | New |
| 76 | TWO SIGMA INVESTMENTS#76 · 45,361 sh | 45,361 | $1.0M | <0.01% | +148.5% |
| 77 | Rafferty Asset Management#77 · 42,629 sh | 42,629 | $947.2K | <0.01% | New |
| 78 | RHUMBLINE ADVISERS#78 · 40,908 sh | 40,908 | $909.0K | <0.01% | +0.9% |
| 79 | VANGUARD ASSET MANAGEMENT, Ltd#79 · 36,587 sh | 36,587 | $813.0K | <0.01% | New |
| 80 | DEUTSCHE BANK AG\#80 · 34,682 sh | 34,682 | $770.6K | <0.01% | -11.5% |
| 81 | Vanguard Global Advisers#81 · 34,093 sh | 34,093 | $757.5K | <0.01% | +43.9% |
| 82 | STATE OF WISCONSIN INVESTMENT BOARD#82 · 31,613 sh | 31,613 | $702.4K | <0.01% | +110.5% |
| 83 | ALLIANCEBERNSTEIN L.P.#83 · 47,330 sh | 47,330 | $665.0K | <0.01% | +4.4% |
| 84 | WELLS FARGO & COMPANY#84 · 29,721 sh | 29,721 | $660.4K | <0.01% | +146.7% |
| 85 | Voleon Capital Management#85 · 27,777 sh | 27,777 | $617.2K | 0.01% | New |
| 86 | PRICE T ROWE ASSOCIATES#86 · 26,546 sh | 26,546 | $590.0K | <0.01% | +17.6% |
| 87 | Man Group plc#87 · 26,123 sh | 26,123 | $580.5K | <0.01% | New |
| 88 | Legal & General Group Plc#88 · 23,420 sh | 23,420 | $520.4K | <0.01% | +734.9% |
| 89 | BARCLAYS PLC#89 · 22,634 sh | 22,634 | $502.9K | <0.01% | -8.2% |
| 90 | Engineers Gate Manager#90 · 22,619 sh | 22,619 | $502.6K | <0.01% | New |
| 91 | Aquatic Capital Management#91 · 22,431 sh | 22,431 | $498.4K | 0.02% | New |
| 92 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#92 · 21,486 sh | 21,486 | $477.4K | <0.01% | +4258.2% |
| 93 | PROFUND ADVISORS#93 · 21,412 sh | 21,412 | $475.8K | 0.01% | New |
| 94 | Virtus Investment Advisers#94 · 21,329 sh | 21,329 | $473.9K | 0.11% | +17.2% |
| 95 | Ghisallo Capital Management#95 · 20,000 sh | 20,000 | $444.4K | <0.01% | New |
| 96 | MIRAE ASSET GLOBAL ETFS Ltd.#96 · 19,943 sh | 19,943 | $442.6K | <0.01% | +33.3% |
| 97 | MetLife Investment Management#97 · 19,739 sh | 19,739 | $438.6K | <0.01% | +10.1% |
| 98 | Invesco Ltd.#98 · 18,119 sh | 18,119 | $402.6K | 0.00% | -38.7% |
| 99 | KLP KAPITALFORVALTNING AS#99 · 13,800 sh | 13,800 | $306.6K | <0.01% | New |
| 100 | AQR CAPITAL MANAGEMENT#100 · 13,311 sh | 13,311 | $295.8K | <0.01% | New |
Funds that sold out of JBIO in Q2 2026 (16)
Held JBIO at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| GREAT POINT PARTNERS964,462 sh | 964,462 | $13.6M |
| DRIEHAUS CAPITAL MANAGEMENT635,498 sh | 635,498 | $8.9M |
| RTW INVESTMENTS573,205 sh | 573,205 | $8.1M |
| ORBIMED ADVISORS185,011 sh | 185,011 | $2.6M |
| StemPoint Capital154,034 sh | 154,034 | $2.2M |
| Y-Intercept (Hong Kong) Ltd25,131 sh | 25,131 | $353.1K |
| Qube Research & Technologies Ltd24,792 sh | 24,792 | $348.3K |
| HRT FINANCIAL24,422 sh | 24,422 | $343.0K |
| ADAR1 Capital Management20,000 sh | 20,000 | $281.0K |
| GSA CAPITAL PARTNERS LLP19,555 sh | 19,555 | $275.0K |
| ExodusPoint Capital Management14,131 sh | 14,131 | $198.5K |
| SUMMIT SECURITIES GROUP1,135 sh | 1,135 | $15.9K |
| Advisory Services Network275 sh | 275 | $3.9K |
| SIMPLEX TRADING83 sh | 83 | $1.2K |
| MAI Capital Management6 sh | 6 | $85.00 |
| Root Financial Partners1 sh | 1 | $14.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.