HERON THERAPEUTICS, INC. /DE/ (HRTX) — Institutional Holders, Q2 2026
163 institutional investment managers reported a HRTX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $57.2M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
HRTX in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- MARSHALL WACE, LLPNew · +2,354,193 sh+$1.0M
- Qube Research & Technologies LtdAdded · +990,737 sh+$422.8K
- GSA CAPITAL PARTNERS LLPAdded · +937,828 sh+$400.3K
- AQR CAPITAL MANAGEMENTAdded · +912,270 sh+$389.4K
- UBS Group AGAdded · +711,190 sh+$303.5K
Biggest sellers
- ORBIMED ADVISORSSold out · -9,816,940 sh-$4.2M
- PALISADE CAPITAL MANAGEMENTSold out · -6,140,639 sh-$2.6M
- MILLENNIUM MANAGEMENTTrimmed · -3,560,426 sh-$1.5M
- D. E. ShawTrimmed · -2,480,555 sh-$1.1M
- Congress Park CapitalTrimmed · -2,016,290 sh-$860.6K
HRTX 13F holders ranked 1–100 of 163
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | Rubric Capital Management#1 · 30,046,828 sh | 30,046,828 | $12.8M | 0.12% | 0.0% |
| 2 | Clearline Capital#2 · 11,383,961 sh | 11,383,961 | $4.9M | 0.29% | -7.0% |
| 3 | BlackRock#3 · 10,550,750 sh | 10,550,750 | $4.5M | <0.01% | +4.4% |
| 4 | Velan Capital Investment Management#4 · 8,753,290 sh | 8,753,290 | $3.7M | 2.28% | 0.0% |
| 5 | VANGUARD CAPITAL MANAGEMENT#5 · 7,782,741 sh | 7,782,741 | $3.3M | <0.01% | -0.4% |
| 6 | Tejara Capital Ltd#6 · 6,510,795 sh | 6,510,795 | $2.8M | 1.14% | +2.7% |
| 7 | TANG CAPITAL MANAGEMENT#7 · 6,250,000 sh | 6,250,000 | $2.7M | 0.12% | 0.0% |
| 8 | GEODE CAPITAL MANAGEMENT#8 · 4,270,980 sh | 4,270,980 | $1.8M | <0.01% | +6.5% |
| 9 | MILLENNIUM MANAGEMENT#9 · 4,070,101 sh | 4,070,101 | $1.7M | <0.01% | -46.7% |
| 10 | JW Asset Management#10 · 3,751,073 sh | 3,751,073 | $1.6M | 0.50% | 0.0% |
| 11 | STATE STREET#11 · 3,228,557 sh | 3,228,557 | $1.4M | 0.00% | -16.0% |
| 12 | UBS Group AG#12 · 2,997,073 sh | 2,997,073 | $1.3M | <0.01% | +31.1% |
| 13 | Pale Fire Capital SE#13 · 2,511,478 sh | 2,511,478 | $1.1M | 0.08% | -7.5% |
| 14 | MARSHALL WACE, LLP#14 · 2,354,193 sh | 2,354,193 | $1.0M | <0.01% | New |
| 15 | Congress Park Capital#15 · 2,016,447 sh | 2,016,447 | $860.6K | — | -50.0% |
| 16 | Richmond Brothers#16 · 1,792,319 sh | 1,792,319 | $765.0K | 0.40% | +24.8% |
| 17 | VANGUARD PORTFOLIO MANAGEMENT#17 · 1,580,510 sh | 1,580,510 | $674.9K | 0.00% | +20.7% |
| 18 | AQR CAPITAL MANAGEMENT#18 · 1,553,857 sh | 1,553,857 | $663.2K | <0.01% | +142.2% |
| 19 | RENAISSANCE TECHNOLOGIES#19 · 1,506,900 sh | 1,506,900 | $643.1K | <0.01% | -12.3% |
| 20 | VANGUARD FIDUCIARY#20 · 1,365,119 sh | 1,365,119 | $582.9K | <0.01% | +18.4% |
| 21 | GOLDMAN SACHS GROUP#21 · 1,329,754 sh | 1,329,754 | $567.5K | 0.00% | +25.8% |
| 22 | PANAGORA ASSET MANAGEMENT#22 · 1,281,796 sh | 1,281,796 | $547.1K | <0.01% | +33.2% |
| 23 | NORTHERN#23 · 1,223,480 sh | 1,223,480 | $522.2K | <0.01% | +4.3% |
| 24 | CHARLES SCHWAB INVESTMENT MANAGEMENT#24 · 1,217,463 sh | 1,217,463 | $519.6K | <0.01% | -11.5% |
| 25 | GSA CAPITAL PARTNERS LLP#25 · 1,042,892 sh | 1,042,892 | $445.0K | 0.03% | +892.6% |
| 26 | Qube Research & Technologies Ltd#26 · 1,021,092 sh | 1,021,092 | $435.8K | <0.01% | +3263.8% |
| 27 | Caption Management#27 · 1,000,000 sh | 1,000,000 | $426.8K | <0.01% | +218.8% |
| 28 | CM Management#28 · 1,000,000 sh | 1,000,000 | $426.8K | 0.27% | 0.0% |
| 29 | NEW YORK STATE COMMON RETIREMENT FUND#29 · 694,165 sh | 694,165 | $296.3K | <0.01% | -73.1% |
| 30 | ALLIANCEBERNSTEIN L.P.#30 · 299,910 sh | 299,910 | $240.0K | <0.01% | +51.1% |
| 31 | Stonepine Capital Management#31 · 490,787 sh | 490,787 | $209.5K | 0.10% | -65.0% |
| 32 | NEXPOINT ASSET MANAGEMENT, L.P.#32 · 475,750 sh | 475,750 | $203.1K | 0.01% | 0.0% |
| 33 | DIADEMA PARTNERS#33 · 458,723 sh | 458,723 | $195.8K | 0.02% | New |
| 34 | Invesco Ltd.#34 · 406,668 sh | 406,668 | $173.6K | 0.00% | +24.5% |
| 35 | Excelsior Advisor Network#35 · 405,777 sh | 405,777 | $173.2K | 0.02% | +42.1% |
| 36 | Bank of New York Mellon#36 · 395,838 sh | 395,838 | $168.9K | 0.00% | -2.7% |
| 37 | Apeiron RIA#37 · 370,579 sh | 370,579 | $158.2K | — | +21.2% |
| 38 | Squarepoint Ops#38 · 321,177 sh | 321,177 | $137.1K | <0.01% | -62.7% |
| 39 | Integrated Wealth Concepts#39 · 318,903 sh | 318,903 | $136.1K | <0.01% | +233.9% |
| 40 | Virtu Financial#40 · 283,239 sh | 283,239 | $121.0K | <0.01% | New |
| 41 | TWO SIGMA INVESTMENTS#41 · 266,314 sh | 266,314 | $113.7K | <0.01% | -16.1% |
| 42 | FMR#42 · 226,803 sh | 226,803 | $96.8K | 0.00% | +289.7% |
| 43 | Nuveen#43 · 221,787 sh | 221,787 | $94.7K | 0.00% | -57.9% |
| 44 | Abel Hall#44 · 213,185 sh | 213,185 | $91.0K | — | +1160.9% |
| 45 | RHUMBLINE ADVISERS#45 · 195,537 sh | 195,537 | $83.5K | <0.01% | +6.0% |
| 46 | Quinn Opportunity Partners#46 · 175,344 sh | 175,344 | $74.8K | <0.01% | 0.0% |
| 47 | RAYMOND JAMES FINANCIAL#47 · 158,177 sh | 158,177 | $67.5K | 0.00% | +14.5% |
| 48 | WELLS FARGO & COMPANY#48 · 152,923 sh | 152,923 | $65.3K | 0.00% | +129.8% |
| 49 | ACADIAN ASSET MANAGEMENT#49 · 153,011 sh | 153,011 | $65.0K | <0.01% | -70.2% |
| 50 | DLK Investment Management#50 · 17,890 sh | 17,890 | $62.6K | — | +53.0% |
| 51 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#51 · 137,067 sh | 137,067 | $58.5K | 0.00% | -52.4% |
| 52 | D. E. Shaw#52 · 120,435 sh | 120,435 | $51.4K | 0.00% | -95.4% |
| 53 | LOS ANGELES CAPITAL MANAGEMENT#53 · 120,293 sh | 120,293 | $51.3K | <0.01% | -50.5% |
| 54 | Persistent Asset Partners Ltd#54 · 117,090 sh | 117,090 | $50.0K | 0.01% | New |
| 55 | PRICE T ROWE ASSOCIATES#55 · 111,504 sh | 111,504 | $48.0K | 0.00% | 0.0% |
| 56 | MORGAN STANLEY#56 · 111,698 sh | 111,698 | $47.7K | 0.00% | -78.2% |
| 57 | BANK OF AMERICA#57 · 108,369 sh | 108,369 | $46.2K | 0.00% | -32.7% |
| 58 | Redwood Family Wealth#58 · 105,472 sh | 105,472 | $45.0K | — | +63.5% |
| 59 | Biltmore Family Office#59 · 100,000 sh | 100,000 | $42.7K | <0.01% | 0.0% |
| 60 | DEUTSCHE BANK AG\#60 · 96,300 sh | 96,300 | $41.4K | 0.00% | +3.5% |
| 61 | IEQ CAPITAL#61 · 96,612 sh | 96,612 | $41.2K | <0.01% | +44.3% |
| 62 | BARCLAYS PLC#62 · 91,022 sh | 91,022 | $38.8K | 0.00% | -0.4% |
| 63 | SEARLE#63 · 86,250 sh | 86,250 | $36.8K | <0.01% | 0.0% |
| 64 | Vanguard Global Advisers#64 · 83,756 sh | 83,756 | $35.8K | 0.00% | 0.0% |
| 65 | Russell Investments Group, Ltd.#65 · 81,246 sh | 81,246 | $34.7K | 0.00% | +541.2% |
| 66 | JPMORGAN CHASE#66 · 75,665 sh | 75,665 | $33.0K | 0.00% | +16.2% |
| 67 | CITIGROUP#67 · 74,940 sh | 74,940 | $32.0K | 0.00% | +935.1% |
| 68 | MIRAE ASSET GLOBAL ETFS Ltd.#68 · 73,585 sh | 73,585 | $31.4K | 0.00% | +0.6% |
| 69 | MERCER GLOBAL ADVISORS#69 · 68,291 sh | 68,291 | $29.1K | 0.00% | +66.4% |
| 70 | LPL Financial#70 · 61,112 sh | 61,112 | $26.1K | 0.00% | -22.3% |
| 71 | Cerity Partners#71 · 60,341 sh | 60,341 | $25.8K | 0.00% | +249.9% |
| 72 | COMMONWEALTH EQUITY SERVICES#72 · 59,176 sh | 59,176 | $25.3K | 0.00% | -0.9% |
| 73 | Mariner#73 · 55,972 sh | 55,972 | $23.9K | 0.00% | +58.3% |
| 74 | Chicago Partners Investment Group#74 · 51,254 sh | 51,254 | $23.5K | — | +91.5% |
| 75 | CAPTRUST FINANCIAL ADVISORS#75 · 51,547 sh | 51,547 | $22.0K | 0.00% | +9.0% |
| 76 | R Squared Ltd#76 · 46,708 sh | 46,708 | $19.9K | 0.01% | +38.9% |
| 77 | Centiva Capital#77 · 45,507 sh | 45,507 | $19.4K | <0.01% | New |
| 78 | INTECH INVESTMENT MANAGEMENT#78 · 42,150 sh | 42,150 | $18.0K | <0.01% | 0.0% |
| 79 | HORAN Wealth#79 · 41,590 sh | 41,590 | $17.8K | <0.01% | 0.0% |
| 80 | Prospera Financial Services#80 · 40,565 sh | 40,565 | $17.3K | <0.01% | 0.0% |
| 81 | Cornerstone Select Advisors#81 · 39,964 sh | 39,964 | $17.1K | <0.01% | -32.7% |
| 82 | Neuberger Berman Group#82 · 38,987 sh | 38,987 | $16.6K | 0.00% | New |
| 83 | Police & Firemen's Retirement System of New Jersey#83 · 38,352 sh | 38,352 | $16.4K | <0.01% | 0.0% |
| 84 | GROUP ONE TRADING, L.P.#84 · 37,947 sh | 37,947 | $16.2K | 0.00% | -56.3% |
| 85 | Creative Planning#85 · 35,862 sh | 35,862 | $15.3K | 0.00% | New |
| 86 | Tower Research Capital (TRC)#86 · 35,567 sh | 35,567 | $15.2K | <0.01% | +13.0% |
| 87 | HSBC PLC#87 · 33,381 sh | 33,381 | $14.5K | 0.00% | 0.0% |
| 88 | DDFG#88 · 32,903 sh | 32,903 | $14.0K | — | New |
| 89 | King Wealth Management Group#89 · 32,799 sh | 32,799 | $14.0K | <0.01% | 0.0% |
| 90 | Concurrent Investment Advisors#90 · 31,923 sh | 31,923 | $13.6K | — | 0.0% |
| 91 | WEALTH ENHANCEMENT ADVISORY SERVICES#91 · 32,397 sh | 32,397 | $13.4K | — | +95.1% |
| 92 | CoreCap Advisors#92 · 28,409 sh | 28,409 | $12.1K | — | 0.0% |
| 93 | Cambridge Investment Research Advisors#93 · 27,995 sh | 27,995 | $12.0K | 0.00% | +25.6% |
| 94 | Vanguard Personalized Indexing Management#94 · 27,276 sh | 27,276 | $11.6K | <0.01% | +103.1% |
| 95 | Diversified#95 · 26,492 sh | 26,492 | $11.3K | <0.01% | 0.0% |
| 96 | HRT FINANCIAL#96 · 27,024 sh | 27,024 | $11.0K | 0.00% | New |
| 97 | Pallas Capital Advisors#97 · 25,699 sh | 25,699 | $11.0K | <0.01% | New |
| 98 | JANE STREET GROUP#98 · 25,672 sh | 25,672 | $11.0K | 0.00% | New |
| 99 | TopTier Wealth Management#99 · 25,350 sh | 25,350 | $10.8K | — | -32.1% |
| 100 | Parkway Wealth Management Group#100 · 25,000 sh | 25,000 | $10.7K | — | 0.0% |
Funds that sold out of HRTX in Q2 2026 (22)
Held HRTX at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| ORBIMED ADVISORS9,816,940 sh | 9,816,940 | $7.9M |
| PALISADE CAPITAL MANAGEMENT6,140,639 sh | 6,140,639 | $4.9M |
| Monaco Asset Management SAM858,122 sh | 858,122 | $686.6K |
| CITADEL ADVISORS759,269 sh | 759,269 | $607.5K |
| Orchard Capital Management680,432 sh | 680,432 | $544.4K |
| Universal- Beteiligungs- und Servicegesellschaft mbH458,766 sh | 458,766 | $367.1K |
| Palumbo Wealth Management412,496 sh | 412,496 | $330.0K |
| XTX Topco Ltd209,481 sh | 209,481 | $167.6K |
| GLENMEDE NA82,050 sh | 82,050 | $65.6K |
| NINE MASTS CAPITAL Ltd53,399 sh | 53,399 | $42.7K |
| State of Wyoming50,618 sh | 50,618 | $40.5K |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE45,988 sh | 45,988 | $36.8K |
| ACT Advisors28,443 sh | 28,443 | $22.8K |
| VOYA INVESTMENT MANAGEMENT25,601 sh | 25,601 | $20.5K |
| Red Door Wealth Management18,900 sh | 18,900 | $15.1K |
| ANCHYRA PARTNERS18,043 sh | 18,043 | $14.4K |
| Focus Partners Wealth17,514 sh | 17,514 | $14.0K |
| NICOLET BANKSHARES16,000 sh | 16,000 | $12.9K |
| ENVESTNET ASSET MANAGEMENT13,591 sh | 13,591 | $10.9K |
| MAI Capital Management695 sh | 695 | $557.00 |
| True Wealth Design271 sh | 271 | $217.00 |
| Root Financial Partners263 sh | 263 | $210.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.