ENANTA PHARMACEUTICALS INC (ENTA) — Institutional Holders, Q2 2026
123 institutional investment managers reported a ENTA position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $397.2M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
ENTA in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- ADAR1 Capital ManagementAdded · +1,293,153 sh+$18.9M
- SummitTX Capital, L.P.New · +257,702 sh+$3.8M
- GOLDMAN SACHS GROUPAdded · +199,561 sh+$2.9M
- ACADIAN ASSET MANAGEMENTAdded · +198,294 sh+$2.9M
- Spruce Street CapitalAdded · +156,133 sh+$2.3M
Biggest sellers
- Deep Track CapitalTrimmed · -512,700 sh-$7.5M
- FARALLON CAPITAL MANAGEMENTTrimmed · -453,660 sh-$6.6M
- MILLENNIUM MANAGEMENTTrimmed · -238,130 sh-$3.5M
- CITADEL ADVISORSTrimmed · -211,689 sh-$3.1M
- TWO SIGMA INVESTMENTSTrimmed · -196,202 sh-$2.9M
ENTA 13F holders ranked 1–100 of 123
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | Jupiter Topco#1 · 3,654,920 sh | 3,654,920 | $53.3M | 0.02% | — |
| 2 | BlackRock#2 · 3,244,448 sh | 3,244,448 | $47.3M | <0.01% | +4.5% |
| 3 | Krensavage Asset Management#3 · 2,866,138 sh | 2,866,138 | $41.8M | 15.88% | 0.0% |
| 4 | FARALLON CAPITAL MANAGEMENT#4 · 2,418,202 sh | 2,418,202 | $35.3M | 0.16% | -15.8% |
| 5 | Deep Track Capital#5 · 1,444,167 sh | 1,444,167 | $21.1M | 0.31% | -26.2% |
| 6 | ADAR1 Capital Management#6 · 1,344,510 sh | 1,344,510 | $19.6M | 0.90% | +2518.0% |
| 7 | VANGUARD CAPITAL MANAGEMENT#7 · 1,211,769 sh | 1,211,769 | $17.7M | <0.01% | +2.9% |
| 8 | Spruce Street Capital#8 · 1,088,731 sh | 1,088,731 | $15.9M | 3.11% | +16.7% |
| 9 | ACADIAN ASSET MANAGEMENT#9 · 1,078,317 sh | 1,078,317 | $15.7M | 0.02% | +22.5% |
| 10 | VANGUARD PORTFOLIO MANAGEMENT#10 · 1,011,494 sh | 1,011,494 | $14.7M | <0.01% | +6.6% |
| 11 | GEODE CAPITAL MANAGEMENT#11 · 776,634 sh | 776,634 | $11.3M | <0.01% | +7.1% |
| 12 | MILLENNIUM MANAGEMENT#12 · 643,967 sh | 643,967 | $9.4M | <0.01% | -27.0% |
| 13 | STATE STREET#13 · 576,117 sh | 576,117 | $8.4M | <0.01% | +2.5% |
| 14 | RENAISSANCE TECHNOLOGIES#14 · 557,600 sh | 557,600 | $8.1M | 0.01% | -16.2% |
| 15 | Hillsdale Investment Management#15 · 468,000 sh | 468,000 | $6.8M | 0.16% | +7.5% |
| 16 | GOLDMAN SACHS GROUP#16 · 464,649 sh | 464,649 | $6.8M | <0.01% | +75.3% |
| 17 | MORGAN STANLEY#17 · 315,729 sh | 315,729 | $4.6M | <0.01% | +2.0% |
| 18 | CHARLES SCHWAB INVESTMENT MANAGEMENT#18 · 301,151 sh | 301,151 | $4.4M | <0.01% | +2.1% |
| 19 | DIMENSIONAL FUND ADVISORS#19 · 282,682 sh | 282,682 | $4.1M | <0.01% | +39.1% |
| 20 | NORTHERN#20 · 259,696 sh | 259,696 | $3.8M | <0.01% | +7.8% |
| 21 | SummitTX Capital, L.P.#21 · 257,702 sh | 257,702 | $3.8M | 0.10% | New |
| 22 | AQR CAPITAL MANAGEMENT#22 · 256,870 sh | 256,870 | $3.7M | <0.01% | -18.0% |
| 23 | VANGUARD FIDUCIARY#23 · 185,618 sh | 185,618 | $2.7M | <0.01% | +5.6% |
| 24 | Connor, Clark & Lunn Investment Management Ltd.#24 · 153,008 sh | 153,008 | $2.2M | <0.01% | +21.7% |
| 25 | Rockefeller Capital Management L.P.#25 · 150,546 sh | 150,546 | $2.2M | <0.01% | +5773.8% |
| 26 | MARSHALL WACE, LLP#26 · 131,995 sh | 131,995 | $1.9M | <0.01% | -37.2% |
| 27 | Opaleye Management#27 · 125,000 sh | 125,000 | $1.8M | 0.17% | 0.0% |
| 28 | JPMORGAN CHASE#28 · 96,764 sh | 96,764 | $1.4M | <0.01% | -6.1% |
| 29 | Russell Investments Group, Ltd.#29 · 84,231 sh | 84,231 | $1.2M | <0.01% | +15.6% |
| 30 | WELLINGTON MANAGEMENT GROUP LLP#30 · 81,633 sh | 81,633 | $1.2M | <0.01% | +8.9% |
| 31 | Qube Research & Technologies Ltd#31 · 81,005 sh | 81,005 | $1.2M | <0.01% | -30.7% |
| 32 | Bank of New York Mellon#32 · 76,756 sh | 76,756 | $1.1M | <0.01% | +8.4% |
| 33 | XTX Topco Ltd#33 · 75,468 sh | 75,468 | $1.1M | 0.01% | +127.2% |
| 34 | TWO SIGMA INVESTMENTS#34 · 71,162 sh | 71,162 | $1.0M | <0.01% | -73.4% |
| 35 | Campbell & Investment Adviser#35 · 70,764 sh | 70,764 | $1.0M | 0.05% | +76.0% |
| 36 | Trexquant Investment#36 · 69,613 sh | 69,613 | $1.0M | <0.01% | +23.9% |
| 37 | MACKENZIE FINANCIAL#37 · 67,367 sh | 67,367 | $982.2K | <0.01% | New |
| 38 | SEI INVESTMENTS#38 · 66,685 sh | 66,685 | $972.3K | <0.01% | -38.9% |
| 39 | UBS Group AG#39 · 64,319 sh | 64,319 | $937.8K | <0.01% | +0.8% |
| 40 | Invesco Ltd.#40 · 59,530 sh | 59,530 | $867.9K | <0.01% | -67.3% |
| 41 | Nuveen#41 · 57,131 sh | 57,131 | $833.0K | <0.01% | +9.3% |
| 42 | CITADEL ADVISORS#42 · 50,844 sh | 50,844 | $741.3K | <0.01% | -80.6% |
| 43 | FRANKLIN RESOURCES#43 · 48,518 sh | 48,518 | $707.4K | <0.01% | -27.5% |
| 44 | Quantinno Capital Management#44 · 45,109 sh | 45,109 | $657.7K | <0.01% | +28.4% |
| 45 | STATE OF WISCONSIN INVESTMENT BOARD#45 · 40,908 sh | 40,908 | $596.4K | <0.01% | +119.8% |
| 46 | PRUDENTIAL FINANCIAL#46 · 39,865 sh | 39,865 | $581.2K | <0.01% | +4.9% |
| 47 | IEQ CAPITAL#47 · 38,508 sh | 38,508 | $561.4K | <0.01% | -0.4% |
| 48 | PANAGORA ASSET MANAGEMENT#48 · 34,789 sh | 34,789 | $507.2K | <0.01% | -61.2% |
| 49 | RHUMBLINE ADVISERS#49 · 34,571 sh | 34,571 | $504.0K | <0.01% | +10.1% |
| 50 | D. E. Shaw#50 · 34,539 sh | 34,539 | $503.6K | <0.01% | -51.3% |
| 51 | BANK OF MONTREAL#51 · 33,868 sh | 33,868 | $493.8K | <0.01% | 0.0% |
| 52 | ALLIANCEBERNSTEIN L.P.#52 · 37,900 sh | 37,900 | $478.7K | <0.01% | +12.3% |
| 53 | GSA CAPITAL PARTNERS LLP#53 · 32,486 sh | 32,486 | $474.0K | 0.03% | New |
| 54 | ALPS ADVISORS#54 · 29,508 sh | 29,508 | $430.2K | <0.01% | New |
| 55 | FMR#55 · 29,505 sh | 29,505 | $430.2K | 0.00% | +8.2% |
| 56 | THRIVENT FINANCIAL FOR LUTHERANS#56 · 28,376 sh | 28,376 | $414.0K | <0.01% | 0.0% |
| 57 | DEUTSCHE BANK AG\#57 · 27,951 sh | 27,951 | $407.5K | <0.01% | +44.1% |
| 58 | WELLS FARGO & COMPANY#58 · 24,935 sh | 24,935 | $363.6K | <0.01% | +138.7% |
| 59 | Portland Global Advisors#59 · 24,275 sh | 24,275 | $353.9K | 0.03% | 0.0% |
| 60 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#60 · 24,112 sh | 24,112 | $351.6K | 0.00% | +69.7% |
| 61 | MARTINGALE ASSET MANAGEMENT L P#61 · 23,778 sh | 23,778 | $346.7K | <0.01% | +43.7% |
| 62 | PRICE T ROWE ASSOCIATES#62 · 23,297 sh | 23,297 | $340.0K | 0.00% | +24.6% |
| 63 | BANK OF AMERICA#63 · 21,536 sh | 21,536 | $314.0K | 0.00% | -19.0% |
| 64 | BRIDGEWAY CAPITAL MANAGEMENT#64 · 20,400 sh | 20,400 | $297.4K | <0.01% | -8.1% |
| 65 | BARCLAYS PLC#65 · 18,655 sh | 18,655 | $272.0K | <0.01% | +1.4% |
| 66 | Headlands Technologies#66 · 17,686 sh | 17,686 | $257.9K | 0.03% | -21.8% |
| 67 | Susquehanna Portfolio Strategies#67 · 17,243 sh | 17,243 | $251.4K | <0.01% | New |
| 68 | MetLife Investment Management#68 · 15,542 sh | 15,542 | $226.6K | <0.01% | 0.0% |
| 69 | BALYASNY ASSET MANAGEMENT L.P.#69 · 14,915 sh | 14,915 | $217.5K | <0.01% | New |
| 70 | CITIGROUP#70 · 13,878 sh | 13,878 | $202.3K | <0.01% | +568.2% |
| 71 | Engineers Gate Manager#71 · 13,080 sh | 13,080 | $190.7K | <0.01% | -23.1% |
| 72 | MIRAE ASSET GLOBAL ETFS Ltd.#72 · 13,067 sh | 13,067 | $190.5K | <0.01% | +0.7% |
| 73 | WEALTH ENHANCEMENT ADVISORY SERVICES#73 · 13,315 sh | 13,315 | $182.4K | — | -2.2% |
| 74 | Vanguard Global Advisers#74 · 10,549 sh | 10,549 | $153.8K | <0.01% | -54.2% |
| 75 | Police & Firemen's Retirement System of New Jersey#75 · 9,942 sh | 9,942 | $145.0K | <0.01% | +48.9% |
| 76 | SRS Capital Advisors#76 · 7,181 sh | 7,181 | $104.7K | <0.01% | +7878.9% |
| 77 | NEW YORK STATE COMMON RETIREMENT FUND#77 · 6,071 sh | 6,071 | $88.5K | <0.01% | 0.0% |
| 78 | Clearstead#78 · 5,064 sh | 5,064 | $73.8K | <0.01% | 0.0% |
| 79 | China Universal Asset Management , Ltd.#79 · 4,628 sh | 4,628 | $67.5K | <0.01% | -10.1% |
| 80 | BNP PARIBAS FINANCIAL MARKETS#80 · 4,278 sh | 4,278 | $62.4K | 0.00% | -74.5% |
| 81 | STRS OHIO#81 · 3,200 sh | 3,200 | $46.7K | <0.01% | 0.0% |
| 82 | Legal & General Group Plc#82 · 2,810 sh | 2,810 | $41.0K | 0.00% | +15.3% |
| 83 | Ameritas Investment Partners#83 · 2,575 sh | 2,575 | $37.5K | <0.01% | +30.5% |
| 84 | Pinnacle Wealth Planning Services#84 · 2,529 sh | 2,529 | $36.9K | — | 0.0% |
| 85 | Zurcher Kantonalbank (Zurich Cantonalbank)#85 · 1,853 sh | 1,853 | $27.0K | <0.01% | +104.5% |
| 86 | Tower Research Capital (TRC)#86 · 1,607 sh | 1,607 | $23.4K | <0.01% | -65.9% |
| 87 | Versant Capital Management#87 · 1,424 sh | 1,424 | $20.8K | — | 0.0% |
| 88 | GAMMA Investing#88 · 1,355 sh | 1,355 | $19.8K | — | -3.3% |
| 89 | Mirae Asset Global Investments , Ltd.#89 · 1,300 sh | 1,300 | $19.0K | 0.00% | -14.1% |
| 90 | EverSource Wealth Advisors#90 · 1,170 sh | 1,170 | $17.1K | <0.01% | -97.9% |
| 91 | ROYAL BANK OF CANADA#91 · 940 sh | 940 | $13.0K | 0.00% | +754.5% |
| 92 | True Wealth Design#92 · 645 sh | 645 | $9.4K | — | 0.0% |
| 93 | GF FUND MANAGEMENT LTD.#93 · 617 sh | 617 | $9.0K | — | -3.6% |
| 94 | PNC FINANCIAL SERVICES GROUP#94 · 556 sh | 556 | $8.1K | 0.00% | 0.0% |
| 95 | State of Wyoming#95 · 530 sh | 530 | $7.7K | <0.01% | -96.1% |
| 96 | Allworth Financial#96 · 403 sh | 403 | $5.9K | 0.00% | -5.2% |
| 97 | IFP Advisors#97 · 402 sh | 402 | $5.9K | — | +1.5% |
| 98 | Essential Partners#98 · 380 sh | 380 | $5.5K | — | -74.9% |
| 99 | FIFTH THIRD BANCORP#99 · 367 sh | 367 | $5.4K | 0.00% | 0.0% |
| 100 | Sterling Capital Management#100 · 342 sh | 342 | $5.0K | — | -62.1% |
Funds that sold out of ENTA in Q2 2026 (19)
Held ENTA at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| DIADEMA PARTNERS64,952 sh | 64,952 | $820.3K |
| Informed Momentum40,952 sh | 40,952 | $517.2K |
| Sio Capital Management40,000 sh | 40,000 | $505.2K |
| Man Group plc39,234 sh | 39,234 | $495.5K |
| FOX RUN MANAGEMENT, L.L.C.20,501 sh | 20,501 | $249.7K |
| Persistent Asset Partners Ltd16,525 sh | 16,525 | $208.7K |
| Squarepoint Ops13,567 sh | 13,567 | $171.4K |
| Creative Planning12,245 sh | 12,245 | $154.7K |
| TUDOR INVESTMENT ET AL10,381 sh | 10,381 | $131.1K |
| MEEDER ASSET MANAGEMENT2,025 sh | 2,025 | $25.6K |
| SIMPLEX TRADING455 sh | 455 | $5.7K |
| MAI Capital Management177 sh | 177 | $2.2K |
| Root Financial Partners118 sh | 118 | $1.5K |
| Physician Wealth Advisors46 sh | 46 | $581.00 |
| Keating Financial Advisory Services7 sh | 7 | $88.00 |
| TWIN PEAKS WEALTH ADVISORS6 sh | 6 | $76.00 |
| Advisory Services Network4 sh | 4 | $51.00 |
| Wealth Preservation Advisors2 sh | 2 | $25.00 |
| SJS Investment Consulting1 sh | 1 | $13.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.