Ensysce Biosciences, Inc. (ENSC) — Institutional Holders, Q2 2026

18 institutional investment managers reported a ENSC position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $246.1K. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

ENSC in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

5

Added to

5

Trimmed

1

Sold out

2

Biggest buyers

  1. JANE STREET GROUPAdded · +195,263 sh+$56.6K
  2. Virtu FinancialAdded · +82,078 sh+$23.8K
  3. XTX Topco LtdAdded · +52,642 sh+$15.3K
  4. SUSQUEHANNA INTERNATIONAL GROUP, LLPNew · +34,280 sh+$9.9K
  5. CITADEL ADVISORSAdded · +28,830 sh+$8.4K

Biggest sellers

  1. VANGUARD FIDUCIARYSold out · -23,854 sh-$6.9K
  2. GEODE CAPITAL MANAGEMENTTrimmed · -11,692 sh-$3.4K
  3. UBS Group AGSold out · -8,791 sh-$2.5K

ENSC 13F holders ranked 1–18 of 18

Institutional investors reporting a position in Ensysce Biosciences, Inc. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
InstitutionValueQoQ
JANE STREET GROUP#1 · 208,833 sh$60.6K+1438.9%
ADAGE CAPITAL PARTNERS GP, L.L.C.#2 · 149,711 sh$43.4K0.0%
Virtu Financial#3 · 95,391 sh$28.0K+616.5%
PERCEPTIVE ADVISORS#4 · 86,666 sh$25.1K0.0%
CITADEL ADVISORS#5 · 86,193 sh$25.0K+50.3%
XTX Topco Ltd#6 · 77,005 sh$22.3K+216.1%
GEODE CAPITAL MANAGEMENT#7 · 62,188 sh$18.0K-15.8%
SUSQUEHANNA INTERNATIONAL GROUP, LLP#8 · 34,280 sh$9.9KNew
TRU INDEPENDENCE ASSET MANAGEMENT 2#9 · 13,000 sh$3.8K0.0%
TWO SIGMA SECURITIES#10 · 12,953 sh$3.8KNew
VANGUARD CAPITAL MANAGEMENT#11 · 12,854 sh$3.7K0.0%
Tower Research Capital (TRC)#12 · 6,094 sh$1.8K0.0%
BARCLAYS PLC#13 · 1,440 sh$418.00New
SBI Securities , Ltd.#14 · 641 sh$186.00+31.9%
BlackRock#15 · 65 sh$19.000.0%
HRT FINANCIAL#16 · 54,429 sh$15.00New
FNY Investment Advisers#17 · 3,000 sh$0.000.0%
Clear Street Group#18 · 1 sh$0.00New

Funds that sold out of ENSC in Q2 2026 (2)

Held ENSC at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held ENSC in Q1 2026 and reported no position in Q2 2026.
InstitutionValue in Q1 2026
VANGUARD FIDUCIARY23,854 sh$12.9K
UBS Group AG8,791 sh$4.7K

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.