CRESCENT BIOPHARMA, INC. (CBIO) — Institutional Holders, Q2 2026
82 institutional investment managers reported a CBIO position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $532.6M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
CBIO in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- Logos Global ManagementAdded · +1,417,500 sh+$25.5M
- BlackRockAdded · +1,156,037 sh+$20.8M
- Remedium Capital PartnersNew · +361,250 sh+$6.5M
- AMERIPRISE FINANCIALNew · +302,568 sh+$5.4M
- GEODE CAPITAL MANAGEMENTAdded · +280,355 sh+$5.0M
Biggest sellers
- Deep Track CapitalSold out · -453,686 sh-$8.2M
- Alyeska Investment Group, L.P.Sold out · -264,000 sh-$4.8M
- GOLDMAN SACHS GROUPSold out · -228,475 sh-$4.1M
- SUSQUEHANNA INTERNATIONAL GROUP, LLPSold out · -213,635 sh-$3.8M
- Hudson Bay Capital ManagementSold out · -88,867 sh-$1.6M
CBIO 13F holders ranked 1–82 of 82
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | FMR#1 · 4,133,514 sh | 4,133,514 | $74.4M | <0.01% | 0.0% |
| 2 | BVF#2 · 2,748,763 sh | 2,748,763 | $49.5M | 1.27% | 0.0% |
| 3 | Fairmount Funds Management#3 · 2,747,866 sh | 2,747,866 | $49.5M | 3.27% | 0.0% |
| 4 | VR Adviser#4 · 2,133,576 sh | 2,133,576 | $38.4M | 1.16% | 0.0% |
| 5 | Logos Global Management#5 · 1,900,000 sh | 1,900,000 | $34.2M | 1.47% | +293.8% |
| 6 | FCPM III SERVICES B.V.#6 · 1,677,852 sh | 1,677,852 | $30.2M | 4.02% | 0.0% |
| 7 | BALYASNY ASSET MANAGEMENT L.P.#7 · 1,662,917 sh | 1,662,917 | $29.9M | 0.04% | +10.1% |
| 8 | Vestal Point Capital#8 · 1,630,000 sh | 1,630,000 | $29.3M | 0.69% | +8.7% |
| 9 | Opaleye Management#9 · 1,319,351 sh | 1,319,351 | $23.7M | 2.15% | +0.5% |
| 10 | BlackRock#10 · 1,271,762 sh | 1,271,762 | $22.9M | <0.01% | +999.0% |
| 11 | TANG CAPITAL MANAGEMENT#11 · 1,160,000 sh | 1,160,000 | $20.9M | 0.95% | 0.0% |
| 12 | VANGUARD CAPITAL MANAGEMENT#12 · 767,755 sh | 767,755 | $13.8M | <0.01% | -4.2% |
| 13 | Boxer Capital Management#13 · 453,686 sh | 453,686 | $8.2M | 0.61% | 0.0% |
| 14 | MILLENNIUM MANAGEMENT#14 · 403,859 sh | 403,859 | $7.3M | <0.01% | +24.8% |
| 15 | GEODE CAPITAL MANAGEMENT#15 · 384,576 sh | 384,576 | $6.9M | <0.01% | +269.0% |
| 16 | JENNISON ASSOCIATES#16 · 378,507 sh | 378,507 | $6.8M | <0.01% | +147.4% |
| 17 | RTW INVESTMENTS#17 · 372,856 sh | 372,856 | $6.7M | 0.06% | 0.0% |
| 18 | NEXTBio Capital Management#18 · 372,856 sh | 372,856 | $6.7M | 3.09% | 0.0% |
| 19 | Remedium Capital Partners#19 · 361,250 sh | 361,250 | $6.5M | 1.44% | 0.0% |
| 20 | STATE STREET#20 · 315,587 sh | 315,587 | $5.7M | <0.01% | +707.8% |
| 21 | AMERIPRISE FINANCIAL#21 · 302,568 sh | 302,568 | $5.4M | <0.01% | New |
| 22 | Point72 Asset Management, L.P.#22 · 300,000 sh | 300,000 | $5.4M | <0.01% | 0.0% |
| 23 | PRICE T ROWE ASSOCIATES#23 · 275,581 sh | 275,581 | $5.0M | <0.01% | -9.2% |
| 24 | MARSHALL WACE, LLP#24 · 214,300 sh | 214,300 | $3.9M | <0.01% | +6.7% |
| 25 | PERCEPTIVE ADVISORS#25 · 206,942 sh | 206,942 | $3.7M | 0.06% | 0.0% |
| 26 | VANGUARD PORTFOLIO MANAGEMENT#26 · 188,803 sh | 188,803 | $3.4M | <0.01% | New |
| 27 | TWO SIGMA INVESTMENTS#27 · 186,874 sh | 186,874 | $3.4M | <0.01% | +61.3% |
| 28 | StemPoint Capital#28 · 182,382 sh | 182,382 | $3.3M | 0.57% | New |
| 29 | UBS Group AG#29 · 175,182 sh | 175,182 | $3.2M | <0.01% | +111.8% |
| 30 | NORTHERN#30 · 138,778 sh | 138,778 | $2.5M | <0.01% | +705.5% |
| 31 | Exome Asset Management#31 · 127,769 sh | 127,769 | $2.3M | 1.42% | -16.6% |
| 32 | SECTORAL ASSET MANAGEMENT#32 · 121,300 sh | 121,300 | $2.2M | 1.52% | New |
| 33 | Woodline Partners#33 · 94,488 sh | 94,488 | $1.7M | <0.01% | +27.7% |
| 34 | VANGUARD FIDUCIARY#34 · 75,225 sh | 75,225 | $1.4M | <0.01% | +52.2% |
| 35 | Burkehill Global Management#35 · 74,000 sh | 74,000 | $1.3M | 0.05% | 0.0% |
| 36 | Blackstone#36 · 62,647 sh | 62,647 | $1.1M | <0.01% | New |
| 37 | SILVERARC CAPITAL MANAGEMENT#37 · 59,104 sh | 59,104 | $1.1M | 0.11% | -54.7% |
| 38 | Y-Intercept (Hong Kong) Ltd#38 · 50,824 sh | 50,824 | $914.8K | — | New |
| 39 | CHARLES SCHWAB INVESTMENT MANAGEMENT#39 · 50,258 sh | 50,258 | $904.6K | <0.01% | New |
| 40 | Nuveen#40 · 47,629 sh | 47,629 | $857.3K | <0.01% | New |
| 41 | Bank of New York Mellon#41 · 45,778 sh | 45,778 | $824.0K | <0.01% | New |
| 42 | Stonepine Capital Management#42 · 40,000 sh | 40,000 | $720.0K | 0.34% | -52.9% |
| 43 | BANK OF AMERICA#43 · 25,821 sh | 25,821 | $464.8K | 0.00% | -11.8% |
| 44 | RHUMBLINE ADVISERS#44 · 25,487 sh | 25,487 | $458.8K | <0.01% | New |
| 45 | MOORE CAPITAL MANAGEMENT#45 · 25,000 sh | 25,000 | $450.0K | <0.01% | 0.0% |
| 46 | Squarepoint Ops#46 · 24,166 sh | 24,166 | $435.0K | <0.01% | New |
| 47 | AMERICAN CENTURY COMPANIES#47 · 22,805 sh | 22,805 | $410.5K | <0.01% | New |
| 48 | WELLS FARGO & COMPANY#48 · 19,700 sh | 19,700 | $354.6K | <0.01% | New |
| 49 | Quadrature Capital Ltd#49 · 19,227 sh | 19,227 | $346.1K | <0.01% | -8.1% |
| 50 | ADAR1 Capital Management#50 · 18,275 sh | 18,275 | $328.9K | 0.02% | -63.6% |
| 51 | Virtus Investment Advisers#51 · 18,258 sh | 18,258 | $328.6K | 0.08% | New |
| 52 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#52 · 17,755 sh | 17,755 | $319.6K | <0.01% | -28.7% |
| 53 | MORGAN STANLEY#53 · 17,698 sh | 17,698 | $318.6K | 0.00% | -4.7% |
| 54 | WELLINGTON MANAGEMENT GROUP LLP#54 · 14,600 sh | 14,600 | $262.8K | 0.00% | New |
| 55 | BANK OF MONTREAL#55 · 13,768 sh | 13,768 | $247.8K | <0.01% | New |
| 56 | MetLife Investment Management#56 · 12,780 sh | 12,780 | $230.0K | <0.01% | New |
| 57 | Invesco Ltd.#57 · 11,731 sh | 11,731 | $211.2K | 0.00% | New |
| 58 | Persistent Asset Partners Ltd#58 · 10,968 sh | 10,968 | $197.4K | 0.06% | New |
| 59 | XTX Topco Ltd#59 · 10,564 sh | 10,564 | $190.2K | <0.01% | New |
| 60 | CITIGROUP#60 · 10,141 sh | 10,141 | $182.5K | <0.01% | -49.7% |
| 61 | MIRAE ASSET GLOBAL ETFS Ltd.#61 · 9,901 sh | 9,901 | $178.2K | <0.01% | New |
| 62 | JPMORGAN CHASE#62 · 9,020 sh | 9,020 | $162.4K | 0.00% | -78.0% |
| 63 | NEW YORK STATE COMMON RETIREMENT FUND#63 · 7,600 sh | 7,600 | $136.8K | <0.01% | New |
| 64 | Police & Firemen's Retirement System of New Jersey#64 · 6,369 sh | 6,369 | $114.6K | <0.01% | New |
| 65 | BARCLAYS PLC#65 · 4,462 sh | 4,462 | $80.3K | 0.00% | -85.2% |
| 66 | BNP PARIBAS FINANCIAL MARKETS#66 · 3,303 sh | 3,303 | $59.5K | 0.00% | -79.0% |
| 67 | Vanguard Global Advisers#67 · 2,714 sh | 2,714 | $48.9K | 0.00% | -21.8% |
| 68 | Legal & General Group Plc#68 · 2,097 sh | 2,097 | $37.7K | 0.00% | New |
| 69 | Tower Research Capital (TRC)#69 · 1,761 sh | 1,761 | $31.7K | <0.01% | New |
| 70 | Russell Investments Group, Ltd.#70 · 1,726 sh | 1,726 | $31.1K | 0.00% | New |
| 71 | ROYAL BANK OF CANADA#71 · 681 sh | 681 | $12.0K | 0.00% | +1235.3% |
| 72 | US BANCORP \DE\#72 · 403 sh | 403 | $7.3K | 0.00% | New |
| 73 | Parallel Advisors#73 · 264 sh | 264 | $4.8K | <0.01% | 0.0% |
| 74 | Allworth Financial#74 · 161 sh | 161 | $2.9K | 0.00% | 0.0% |
| 75 | Sterling Capital Management#75 · 76 sh | 76 | $1.4K | — | New |
| 76 | SBI Securities , Ltd.#76 · 68 sh | 68 | $1.2K | — | 0.0% |
| 77 | Fortitude Family Office#77 · 40 sh | 40 | $720.00 | — | 0.0% |
| 78 | Quarry#78 · 29 sh | 29 | $522.00 | 0.00% | New |
| 79 | OSAIC#79 · 26 sh | 26 | $468.00 | 0.00% | 0.0% |
| 80 | Caitong International Asset Management , Ltd#80 · 21 sh | 21 | $378.00 | <0.01% | +425.0% |
| 81 | NATIONAL BANK OF CANADA#81 · 3 sh | 3 | $54.00 | 0.00% | New |
| 82 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM#82 · 297 sh | 297 | — | — | New |
Funds that sold out of CBIO in Q2 2026 (12)
Held CBIO at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Deep Track Capital453,686 sh | 453,686 | $8.3M |
| Alyeska Investment Group, L.P.264,000 sh | 264,000 | $4.8M |
| GOLDMAN SACHS GROUP228,475 sh | 228,475 | $4.2M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP213,635 sh | 213,635 | $3.9M |
| Hudson Bay Capital Management88,867 sh | 88,867 | $1.6M |
| Lighthouse Investment Partners25,000 sh | 25,000 | $459.3K |
| RENAISSANCE TECHNOLOGIES24,262 sh | 24,262 | $445.7K |
| Brevan Howard Capital Management19,530 sh | 19,530 | $358.8K |
| OMERS ADMINISTRATION17,800 sh | 17,800 | $327.0K |
| ALGERT GLOBAL13,806 sh | 13,806 | $254.0K |
| Verdad Advisers12,748 sh | 12,748 | $234.2K |
| Cannon Global Investment Management10,200 sh | 10,200 | $187.4K |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.