Caris Life Sciences, Inc. (CAI) — Institutional Holders, Q2 2026
248 institutional investment managers reported a CAI position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $2.7B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
CAI in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- JPMORGAN CHASEAdded · +3,098,299 sh+$55.2M
- MAK CAPITAL ONENew · +1,937,229 sh+$34.5M
- LOS ANGELES CAPITAL MANAGEMENTAdded · +1,668,929 sh+$29.7M
- HRT FINANCIALNew · +1,418,392 sh+$25.3M
- AmundiAdded · +1,197,392 sh+$21.3M
Biggest sellers
- Sixth Street Partners Management Company, L.P.Trimmed · -7,058,358 sh-$125.8M
- J. H. Whitney Equity Partners VITrimmed · -7,000,000 sh-$124.7M
- PRICE T ROWE ASSOCIATESTrimmed · -3,166,381 sh-$56.4M
- UBS Group AGTrimmed · -1,322,440 sh-$23.6M
- UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMETrimmed · -1,148,363 sh-$20.5M
CAI 13F holders ranked 1–100 of 248
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | FMR#1 · 30,923,878 sh | 30,923,878 | $551.1M | 0.02% | +0.4% |
| 2 | J. H. Whitney Equity Partners VI#2 · 11,256,615 sh | 11,256,615 | $200.6M | 100.00% | -38.3% |
| 3 | COATUE MANAGEMENT#3 · 9,819,992 sh | 9,819,992 | $175.0M | 0.36% | 0.0% |
| 4 | BRAIDWELL#4 · 8,256,032 sh | 8,256,032 | $147.1M | 5.44% | +3.1% |
| 5 | Sixth Street Partners Management Company, L.P.#5 · 7,327,041 sh | 7,327,041 | $130.6M | 22.54% | -49.1% |
| 6 | PointState Capital#6 · 6,828,835 sh | 6,828,835 | $121.7M | 1.56% | -7.2% |
| 7 | JPMORGAN CHASE#7 · 6,558,514 sh | 6,558,514 | $120.2M | <0.01% | +89.5% |
| 8 | BlackRock#8 · 5,536,798 sh | 5,536,798 | $98.7M | <0.01% | +14.0% |
| 9 | T. Rowe Price Investment Management#9 · 5,079,141 sh | 5,079,141 | $90.5M | 0.06% | -9.1% |
| 10 | VANGUARD PORTFOLIO MANAGEMENT#10 · 4,844,431 sh | 4,844,431 | $86.3M | <0.01% | +28.9% |
| 11 | VANGUARD CAPITAL MANAGEMENT#11 · 4,280,238 sh | 4,280,238 | $76.3M | <0.01% | +28.6% |
| 12 | LOS ANGELES CAPITAL MANAGEMENT#12 · 3,958,531 sh | 3,958,531 | $70.5M | 0.26% | +72.9% |
| 13 | Neuberger Berman Group#13 · 3,590,963 sh | 3,590,963 | $64.0M | 0.04% | 0.0% |
| 14 | ORBIMED ADVISORS#14 · 2,806,811 sh | 2,806,811 | $50.0M | 0.93% | 0.0% |
| 15 | BNP PARIBAS FINANCIAL MARKETS#15 · 2,370,268 sh | 2,370,268 | $42.2M | 0.01% | +46.8% |
| 16 | MILLENNIUM MANAGEMENT#16 · 2,202,647 sh | 2,202,647 | $39.3M | 0.01% | +44.2% |
| 17 | MAK CAPITAL ONE#17 · 1,937,229 sh | 1,937,229 | $34.5M | 4.84% | New |
| 18 | MORGAN STANLEY#18 · 1,935,531 sh | 1,935,531 | $34.5M | <0.01% | +79.3% |
| 19 | Duquesne Family Office#19 · 1,894,450 sh | 1,894,450 | $33.8M | 0.65% | 0.0% |
| 20 | Clearbridge Investments#20 · 1,595,877 sh | 1,595,877 | $28.4M | 0.02% | +2.8% |
| 21 | FIL Ltd#21 · 1,548,918 sh | 1,548,918 | $27.6M | 0.02% | +0.2% |
| 22 | UBS Group AG#22 · 1,423,371 sh | 1,423,371 | $25.4M | <0.01% | -48.2% |
| 23 | HRT FINANCIAL#23 · 1,418,392 sh | 1,418,392 | $25.3M | 0.06% | New |
| 24 | CANADA PENSION PLAN INVESTMENT BOARD#24 · 1,374,952 sh | 1,374,952 | $24.5M | 0.01% | +3.9% |
| 25 | STATE STREET#25 · 1,217,548 sh | 1,217,548 | $21.7M | <0.01% | +23.6% |
| 26 | Amundi#26 · 1,218,364 sh | 1,218,364 | $21.7M | <0.01% | +5709.5% |
| 27 | Capital World Investors#27 · 1,213,272 sh | 1,213,272 | $21.6M | <0.01% | +2.8% |
| 28 | PRICE T ROWE ASSOCIATES#28 · 1,205,390 sh | 1,205,390 | $21.5M | <0.01% | -72.4% |
| 29 | BANK OF AMERICA#29 · 1,200,590 sh | 1,200,590 | $21.4M | <0.01% | +129.4% |
| 30 | Champlain Investment Partners#30 · 1,048,862 sh | 1,048,862 | $18.7M | 0.48% | -13.2% |
| 31 | GEODE CAPITAL MANAGEMENT#31 · 1,044,657 sh | 1,044,657 | $18.6M | <0.01% | +34.2% |
| 32 | GOLDMAN SACHS GROUP#32 · 951,942 sh | 951,942 | $17.0M | <0.01% | +132.0% |
| 33 | ZEVENBERGEN CAPITAL INVESTMENTS#33 · 802,083 sh | 802,083 | $14.3M | — | +31.4% |
| 34 | SEI INVESTMENTS#34 · 762,659 sh | 762,659 | $13.6M | 0.01% | +27.4% |
| 35 | Trexquant Investment#35 · 727,944 sh | 727,944 | $13.0M | 0.08% | +48.4% |
| 36 | Woodline Partners#36 · 723,163 sh | 723,163 | $12.9M | 0.04% | 0.0% |
| 37 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP#37 · 655,644 sh | 655,644 | $11.7M | <0.01% | +211.3% |
| 38 | Nuveen#38 · 604,416 sh | 604,416 | $10.8M | <0.01% | -8.9% |
| 39 | AMERIPRISE FINANCIAL#39 · 572,784 sh | 572,784 | $10.2M | <0.01% | +40.4% |
| 40 | RENAISSANCE TECHNOLOGIES#40 · 568,000 sh | 568,000 | $10.1M | 0.01% | +26.3% |
| 41 | Rock Springs Capital Management#41 · 487,500 sh | 487,500 | $8.7M | 0.42% | -13.4% |
| 42 | Quantinno Capital Management#42 · 441,672 sh | 441,672 | $7.9M | <0.01% | +213.4% |
| 43 | Walleye Capital#43 · 424,407 sh | 424,407 | $7.6M | 0.03% | New |
| 44 | Squarepoint Ops#44 · 380,927 sh | 380,927 | $6.8M | <0.01% | New |
| 45 | TD ASSET MANAGEMENT#45 · 379,388 sh | 379,388 | $6.8M | <0.01% | -43.4% |
| 46 | Bank of New York Mellon#46 · 308,407 sh | 308,407 | $5.5M | <0.01% | +33.1% |
| 47 | MENLO ADVISORS#47 · 300,518 sh | 300,518 | $5.4M | 2.35% | New |
| 48 | CITADEL ADVISORS#48 · 297,855 sh | 297,855 | $5.3M | <0.01% | +282.8% |
| 49 | FEDERATED HERMES#49 · 285,598 sh | 285,598 | $5.1M | <0.01% | +19.4% |
| 50 | PICTON MAHONEY ASSET MANAGEMENT#50 · 264,064 sh | 264,064 | $4.7M | 0.03% | -5.3% |
| 51 | NORTHERN#51 · 258,787 sh | 258,787 | $4.6M | <0.01% | +48.7% |
| 52 | NOMURA ASSET MANAGEMENT INTERNATIONAL#52 · 247,605 sh | 247,605 | $4.4M | <0.01% | New |
| 53 | Qube Research & Technologies Ltd#53 · 226,878 sh | 226,878 | $4.0M | <0.01% | +21.0% |
| 54 | MARSHALL WACE, LLP#54 · 222,717 sh | 222,717 | $4.0M | <0.01% | New |
| 55 | Maxi Investments CY Ltd#55 · 210,670 sh | 210,670 | $3.8M | — | New |
| 56 | D. E. Shaw#56 · 204,818 sh | 204,818 | $3.6M | <0.01% | +58.1% |
| 57 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#57 · 204,432 sh | 204,432 | $3.6M | <0.01% | +285.2% |
| 58 | WORLDQUANT MILLENNIUM ADVISORS#58 · 204,152 sh | 204,152 | $3.6M | 0.01% | +4.8% |
| 59 | MIRAE ASSET GLOBAL ETFS Ltd.#59 · 173,010 sh | 173,010 | $3.1M | <0.01% | +470.0% |
| 60 | Militia Capital Management#60 · 166,600 sh | 166,600 | $3.0M | 0.09% | New |
| 61 | SG Americas Securities#61 · 152,236 sh | 152,236 | $2.7M | <0.01% | New |
| 62 | XTX Topco Ltd#62 · 136,488 sh | 136,488 | $2.4M | 0.03% | +73.9% |
| 63 | VANGUARD FIDUCIARY#63 · 132,479 sh | 132,479 | $2.4M | <0.01% | +37.2% |
| 64 | CastleKnight Management#64 · 132,236 sh | 132,236 | $2.4M | 0.03% | +222.2% |
| 65 | Invesco Ltd.#65 · 132,103 sh | 132,103 | $2.4M | <0.01% | -89.2% |
| 66 | NATIXIS#66 · 124,716 sh | 124,716 | $2.2M | <0.01% | +136.3% |
| 67 | STATE OF WISCONSIN INVESTMENT BOARD#67 · 123,129 sh | 123,129 | $2.2M | <0.01% | -9.7% |
| 68 | CITIGROUP#68 · 111,236 sh | 111,236 | $2.0M | <0.01% | +44.1% |
| 69 | ROYAL BANK OF CANADA#69 · 102,044 sh | 102,044 | $1.8M | <0.01% | +447.1% |
| 70 | TUDOR INVESTMENT ET AL#70 · 100,327 sh | 100,327 | $1.8M | <0.01% | 0.0% |
| 71 | Ghisallo Capital Management#71 · 100,000 sh | 100,000 | $1.8M | 0.04% | -60.0% |
| 72 | SALEM INVESTMENT COUNSELORS#72 · 100,000 sh | 100,000 | $1.8M | — | New |
| 73 | RHUMBLINE ADVISERS#73 · 98,849 sh | 98,849 | $1.8M | <0.01% | +32.5% |
| 74 | RAYMOND JAMES FINANCIAL#74 · 98,595 sh | 98,595 | $1.8M | <0.01% | +9.3% |
| 75 | Smartleaf Asset Management#75 · 94,051 sh | 94,051 | $1.7M | 0.06% | 0.0% |
| 76 | Gotham Asset Management#76 · 89,535 sh | 89,535 | $1.6M | <0.01% | -88.0% |
| 77 | Mitsubishi UFJ Asset Management , Ltd.#77 · 85,600 sh | 85,600 | $1.5M | <0.01% | New |
| 78 | Pathstone#78 · 82,782 sh | 82,782 | $1.5M | <0.01% | New |
| 79 | LAZARD ASSET MANAGEMENT#79 · 81,736 sh | 81,736 | $1.5M | <0.01% | -73.3% |
| 80 | ALLIANCEBERNSTEIN L.P.#80 · 81,021 sh | 81,021 | $1.4M | <0.01% | +42.0% |
| 81 | Exome Asset Management#81 · 78,180 sh | 78,180 | $1.4M | 0.86% | New |
| 82 | Creative Planning#82 · 77,456 sh | 77,456 | $1.4M | <0.01% | -0.7% |
| 83 | ENVESTNET ASSET MANAGEMENT#83 · 71,695 sh | 71,695 | $1.3M | <0.01% | +33.7% |
| 84 | Jain Global#84 · 68,222 sh | 68,222 | $1.2M | <0.01% | New |
| 85 | MOORE CAPITAL MANAGEMENT#85 · 63,895 sh | 63,895 | $1.1M | 0.02% | New |
| 86 | JONES FINANCIAL COMPANIES LLLP#86 · 61,237 sh | 61,237 | $1.1M | <0.01% | +398.0% |
| 87 | Renaissance Capital#87 · 62,887 sh | 62,887 | $1.1M | — | +44.6% |
| 88 | NEW YORK STATE COMMON RETIREMENT FUND#88 · 61,300 sh | 61,300 | $1.1M | <0.01% | +34.1% |
| 89 | Cambridge Investment Research Advisors#89 · 59,873 sh | 59,873 | $1.1M | <0.01% | New |
| 90 | AQR CAPITAL MANAGEMENT#90 · 59,103 sh | 59,103 | $1.1M | <0.01% | +103.8% |
| 91 | Sumitomo Mitsui#91 · 54,890 sh | 54,890 | $978.1K | <0.01% | -3.3% |
| 92 | Police & Firemen's Retirement System of New Jersey#92 · 54,057 sh | 54,057 | $963.3K | <0.01% | +36.9% |
| 93 | Treasurer of the State of North Carolina#93 · 52,515 sh | 52,515 | $936.0K | <0.01% | +34.6% |
| 94 | LPL Financial#94 · 51,502 sh | 51,502 | $917.8K | <0.01% | +22.5% |
| 95 | NATIXIS ADVISORS#95 · 49,587 sh | 49,587 | $883.0K | <0.01% | +260.4% |
| 96 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#96 · 47,595 sh | 47,595 | $848.1K | <0.01% | -69.0% |
| 97 | Y-Intercept (Hong Kong) Ltd#97 · 46,068 sh | 46,068 | $820.9K | — | New |
| 98 | China Universal Asset Management , Ltd.#98 · 44,989 sh | 44,989 | $801.7K | 0.05% | -10.1% |
| 99 | Virtu Financial#99 · 44,018 sh | 44,018 | $784.0K | 0.02% | New |
| 100 | DEUTSCHE BANK AG\#100 · 43,653 sh | 43,653 | $777.9K | <0.01% | +14.0% |
Funds that sold out of CAI in Q2 2026 (23)
Held CAI at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Point72 Asset Management, L.P.918,331 sh | 918,331 | $16.4M |
| Parkman Healthcare Partners229,912 sh | 229,912 | $4.1M |
| Man Group plc128,971 sh | 128,971 | $2.3M |
| ODDO BHF ASSET MANAGEMENT SAS109,539 sh | 109,539 | $2.0M |
| Engineers Gate Manager102,757 sh | 102,757 | $1.8M |
| Burkehill Global Management75,000 sh | 75,000 | $1.3M |
| TWINBEECH CAPITAL58,100 sh | 58,100 | $1.0M |
| FRANKLIN RESOURCES44,975 sh | 44,975 | $804.2K |
| AXQ CAPITAL22,125 sh | 22,125 | $395.6K |
| Verition Fund Management20,000 sh | 20,000 | $357.6K |
| HSBC PLC16,494 sh | 16,494 | $294.0K |
| Savant Capital13,803 sh | 13,803 | $246.8K |
| ProShare Advisors12,622 sh | 12,622 | $225.7K |
| JACOBS LEVY EQUITY MANAGEMENT12,340 sh | 12,340 | $220.6K |
| BESSEMER GROUP11,880 sh | 11,880 | $212.0K |
| Wedmont Private Capital10,715 sh | 10,715 | $209.1K |
| LEUCADIA NATIONAL10,745 sh | 10,745 | $192.1K |
| QUADRANT CAPITAL GROUP5,768 sh | 5,768 | $100.5K |
| Ancora Advisors1,923 sh | 1,923 | $34.4K |
| MAI Capital Management1,035 sh | 1,035 | $18.5K |
| CX Institutional684 sh | 684 | $12.0K |
| Advisory Services Network100 sh | 100 | $1.8K |
| Wealth Preservation Advisors3 sh | 3 | $54.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.