BIOCRYST PHARMACEUTICALS INC (BCRX) — Institutional Holders, Q2 2026

319 institutional investment managers reported a BCRX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $2.6B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

← BCRX stock profile

BCRX in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

Added to

129

Trimmed

Sold out

Biggest buyers

MILLENNIUM MANAGEMENTAdded · +3,207,008 sh+$32.1M
STATE STREETAdded · +2,982,738 sh+$29.8M
PERCEPTIVE ADVISORSAdded · +2,874,855 sh+$28.7M
JANE STREET GROUPAdded · +2,140,076 sh+$21.4M
GOLDMAN SACHS GROUPAdded · +2,134,431 sh+$21.3M

Biggest sellers

Royalty Pharma Sub-ManagerSold out · -3,846,154 sh-$38.5M
Kynam Capital ManagementTrimmed · -3,158,135 sh-$31.6M
RFG AdvisorySold out · -2,870,700 sh-$28.7M
SUSQUEHANNA INTERNATIONAL GROUP, LLPTrimmed · -1,619,653 sh-$16.2M
Eversept PartnersTrimmed · -1,174,167 sh-$11.7M

BCRX 13F holders ranked 1–100 of 319

Institutional investors reporting a position in BIOCRYST PHARMACEUTICALS INC on SEC Form 13F-HR for Q2 2026, ranked by reported value.
#	Institution	Shares	Value	% of portfolio	QoQShares vs Q1 2026
1	BlackRock#1 · 23,893,036 sh	23,893,036	$238.9M	<0.01%	+5.5%
2	RA CAPITAL MANAGEMENT, L.P.#2 · 15,827,186 sh	15,827,186	$158.3M	1.38%	0.0%
3	STATE STREET#3 · 15,191,098 sh	15,191,098	$151.9M	<0.01%	+24.4%
4	DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)#4 · 15,096,403 sh	15,096,403	$151.0M	1.57%	+0.4%
5	VANGUARD CAPITAL MANAGEMENT#5 · 11,364,236 sh	11,364,236	$113.6M	<0.01%	+2.1%
6	VANGUARD PORTFOLIO MANAGEMENT#6 · 11,139,158 sh	11,139,158	$111.4M	<0.01%	-0.9%
7	TCG Crossover Management#7 · 11,020,968 sh	11,020,968	$110.2M	2.65%	0.0%
8	PERCEPTIVE ADVISORS#8 · 10,308,888 sh	10,308,888	$103.1M	1.55%	+38.7%
9	Jupiter Topco#9 · 9,540,764 sh	9,540,764	$95.3M	0.04%	—
10	Vestal Point Capital#10 · 8,300,000 sh	8,300,000	$83.0M	1.94%	+18.1%
11	TWO SIGMA INVESTMENTS#11 · 6,775,349 sh	6,775,349	$67.8M	0.05%	+6.0%
12	GEODE CAPITAL MANAGEMENT#12 · 6,248,046 sh	6,248,046	$62.5M	<0.01%	+8.0%
13	abrdn plc#13 · 5,310,871 sh	5,310,871	$53.1M	0.07%	+5.4%
14	UBS Group AG#14 · 5,078,280 sh	5,078,280	$50.8M	<0.01%	+2.7%
15	BANK OF AMERICA#15 · 4,801,284 sh	4,801,284	$48.0M	<0.01%	-5.7%
16	GOLDMAN SACHS GROUP#16 · 4,481,874 sh	4,481,874	$44.8M	<0.01%	+90.9%
17	Frazier Life Sciences Management, L.P.#17 · 4,009,240 sh	4,009,240	$40.1M	0.87%	0.0%
18	Nuveen#18 · 4,007,237 sh	4,007,237	$40.1M	<0.01%	+4.9%
19	MILLENNIUM MANAGEMENT#19 · 3,394,729 sh	3,394,729	$33.9M	0.01%	+1708.4%
20	GW&K Investment Management#20 · 3,171,113 sh	3,171,113	$31.7M	0.25%	-2.1%
21	JANE STREET GROUP#21 · 2,762,683 sh	2,762,683	$27.6M	<0.01%	+343.7%
22	DIMENSIONAL FUND ADVISORS#22 · 2,718,781 sh	2,718,781	$27.2M	<0.01%	+1.0%
23	Fisher Asset Management#23 · 2,604,027 sh	2,604,027	$26.0M	<0.01%	-4.7%
24	RENAISSANCE TECHNOLOGIES#24 · 2,530,290 sh	2,530,290	$25.3M	0.03%	+225.7%
25	Kynam Capital Management#25 · 2,522,660 sh	2,522,660	$25.2M	1.39%	-55.6%
26	Candriam S.C.A.#26 · 2,514,949 sh	2,514,949	$25.1M	0.11%	+10.0%
27	CHARLES SCHWAB INVESTMENT MANAGEMENT#27 · 2,353,291 sh	2,353,291	$23.5M	<0.01%	+0.1%
28	RICE HALL JAMES & ASSOCIATES#28 · 2,332,043 sh	2,332,043	$23.3M	1.14%	+4.6%
29	NORTHERN#29 · 2,255,731 sh	2,255,731	$22.6M	<0.01%	+7.2%
30	AQR CAPITAL MANAGEMENT#30 · 2,214,302 sh	2,214,302	$22.1M	<0.01%	+403.1%
31	MORGAN STANLEY#31 · 1,999,684 sh	1,999,684	$20.0M	<0.01%	-1.2%
32	Nantahala Capital Management#32 · 1,901,160 sh	1,901,160	$19.0M	0.63%	-4.3%
33	Eversept Partners#33 · 1,865,653 sh	1,865,653	$18.7M	0.97%	-38.6%
34	ORBIMED ADVISORS#34 · 1,852,000 sh	1,852,000	$18.5M	0.34%	+29.9%
35	HEALTHCARE OF ONTARIO PENSION PLAN FUND#35 · 1,844,912 sh	1,844,912	$18.4M	0.03%	+50.4%
36	STIFEL FINANCIAL#36 · 1,826,234 sh	1,826,234	$18.3M	0.02%	+0.1%
37	VANGUARD FIDUCIARY#37 · 1,759,573 sh	1,759,573	$17.6M	<0.01%	+5.7%
38	CITADEL ADVISORS#38 · 1,759,160 sh	1,759,160	$17.6M	<0.01%	+72.7%
39	JUPITER ASSET MANAGEMENT LTD#39 · 1,642,874 sh	1,642,874	$16.4M	0.08%	+37.3%
40	IMC-Chicago#40 · 1,634,336 sh	1,634,336	$16.3M	<0.01%	+158.9%
41	Parkman Healthcare Partners#41 · 1,624,279 sh	1,624,279	$16.2M	1.66%	-4.9%
42	Legal & General Group Plc#42 · 1,455,514 sh	1,455,514	$14.6M	<0.01%	+3.1%
43	OP Asset Management Ltd#43 · 1,340,990 sh	1,340,990	$13.4M	0.14%	+7.0%
44	Invesco Ltd.#44 · 1,233,783 sh	1,233,783	$12.3M	<0.01%	-5.7%
45	SUSQUEHANNA INTERNATIONAL GROUP, LLP#45 · 1,195,651 sh	1,195,651	$12.0M	<0.01%	-57.5%
46	Pictet Asset Management Holding SA#46 · 1,249,771 sh	1,249,771	$12.0M	0.01%	+165.0%
47	BNP PARIBAS FINANCIAL MARKETS#47 · 1,174,052 sh	1,174,052	$11.7M	<0.01%	-9.8%
48	FIRST ADVISORS#48 · 1,120,469 sh	1,120,469	$11.2M	<0.01%	+39.9%
49	HRT FINANCIAL#49 · 1,081,523 sh	1,081,523	$10.8M	0.03%	New
50	MOORE CAPITAL MANAGEMENT#50 · 848,336 sh	848,336	$8.5M	0.13%	New
51	FMR#51 · 808,903 sh	808,903	$8.1M	<0.01%	+27.8%
52	ExodusPoint Capital Management#52 · 744,917 sh	744,917	$7.4M	0.05%	+291.9%
53	Man Group plc#53 · 732,867 sh	732,867	$7.3M	0.01%	-43.3%
54	Rosalind Advisors#54 · 721,504 sh	721,504	$7.2M	1.90%	-21.8%
55	Schonfeld Strategic Advisors#55 · 710,816 sh	710,816	$7.1M	0.03%	-46.9%
56	Bank of New York Mellon#56 · 680,481 sh	680,481	$6.8M	<0.01%	+6.7%
57	Jump Financial#57 · 569,956 sh	569,956	$5.7M	0.05%	+420.9%
58	DEUTSCHE BANK AG\#58 · 563,361 sh	563,361	$5.6M	<0.01%	-31.4%
59	VOYA INVESTMENT MANAGEMENT#59 · 538,813 sh	538,813	$5.4M	<0.01%	+0.5%
60	Elmind Capital#60 · 520,000 sh	520,000	$5.2M	1.31%	-48.0%
61	JPMORGAN CHASE#61 · 525,449 sh	525,449	$5.1M	<0.01%	-65.9%
62	Bridgewater Associates#62 · 491,057 sh	491,057	$4.9M	0.02%	-23.0%
63	FRANKLIN RESOURCES#63 · 480,364 sh	480,364	$4.8M	<0.01%	-8.2%
64	PRINCIPAL FINANCIAL GROUP#64 · 468,785 sh	468,785	$4.7M	<0.01%	+8.9%
65	NAN FUNG TRINITY (HK) Ltd#65 · 450,000 sh	450,000	$4.5M	0.44%	New
66	SPHERA FUNDS MANAGEMENT LTD.#66 · 422,051 sh	422,051	$4.2M	0.55%	-51.3%
67	Swiss National Bank#67 · 415,268 sh	415,268	$4.2M	<0.01%	+1.6%
68	D. E. Shaw#68 · 408,529 sh	408,529	$4.1M	<0.01%	+35.2%
69	Susquehanna Portfolio Strategies#69 · 404,704 sh	404,704	$4.0M	0.06%	+8.2%
70	DAFNA Capital Management#70 · 400,248 sh	400,248	$4.0M	0.76%	-7.0%
71	Hudson Bay Capital Management#71 · 400,000 sh	400,000	$4.0M	0.01%	-18.4%
72	WEDGE CAPITAL MANAGEMENT L L P#72 · 380,801 sh	380,801	$3.8M	—	New
73	DOLIVER ADVISORS#73 · 374,328 sh	374,328	$3.7M	—	0.0%
74	Aquatic Capital Management#74 · 362,895 sh	362,895	$3.6M	0.12%	New
75	CITIGROUP#75 · 360,189 sh	360,189	$3.6M	<0.01%	+406.1%
76	Assenagon Asset Management S.A.#76 · 353,044 sh	353,044	$3.5M	—	+51.6%
77	MACKENZIE FINANCIAL#77 · 347,299 sh	347,299	$3.5M	<0.01%	+42.7%
78	Phocas Financial#78 · 340,541 sh	340,541	$3.4M	0.47%	+74.2%
79	UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#79 · 320,566 sh	320,566	$3.2M	<0.01%	-13.1%
80	ALPS ADVISORS#80 · 317,960 sh	317,960	$3.2M	0.01%	+427.7%
81	ALLIANCEBERNSTEIN L.P.#81 · 327,909 sh	327,909	$3.1M	<0.01%	+24.4%
82	PRICE T ROWE ASSOCIATES#82 · 305,897 sh	305,897	$3.1M	<0.01%	+32.4%
83	WELLINGTON MANAGEMENT GROUP LLP#83 · 293,925 sh	293,925	$2.9M	<0.01%	+197.2%
84	RHUMBLINE ADVISERS#84 · 279,839 sh	279,839	$2.8M	<0.01%	+5.1%
85	NFJ INVESTMENT GROUP#85 · 278,792 sh	278,792	$2.8M	0.09%	New
86	Rafferty Asset Management#86 · 265,618 sh	265,618	$2.7M	<0.01%	-25.0%
87	Point72 Asset Management, L.P.#87 · 260,917 sh	260,917	$2.6M	<0.01%	New
88	WINTON GROUP Ltd#88 · 255,600 sh	255,600	$2.6M	0.08%	+380.3%
89	MARSHALL WACE, LLP#89 · 252,764 sh	252,764	$2.5M	<0.01%	+2.6%
90	MARTINGALE ASSET MANAGEMENT L P#90 · 242,508 sh	242,508	$2.4M	0.06%	+329.0%
91	IEQ CAPITAL#91 · 227,421 sh	227,421	$2.3M	0.01%	New
92	WELLS FARGO & COMPANY#92 · 222,894 sh	222,894	$2.2M	<0.01%	-5.9%
93	HUSSMAN STRATEGIC ADVISORS#93 · 210,000 sh	210,000	$2.1M	0.48%	New
94	PFM Health Sciences#94 · 207,357 sh	207,357	$2.1M	0.18%	New
95	VANGUARD ASSET MANAGEMENT, Ltd#95 · 196,280 sh	196,280	$2.0M	<0.01%	0.0%
96	TUDOR INVESTMENT ET AL#96 · 195,128 sh	195,128	$2.0M	<0.01%	New
97	Engineers Gate Manager#97 · 175,002 sh	175,002	$1.8M	0.02%	-10.0%
98	Squarepoint Ops#98 · 174,714 sh	174,714	$1.7M	<0.01%	+339.4%
99	Janney Montgomery Scott#99 · 163,267 sh	163,267	$1.6M	<0.01%	0.0%
100	QTR Family Wealth#100 · 161,082 sh	161,082	$1.6M	0.56%	+2.6%

Funds that sold out of BCRX in Q2 2026 (38)

Held BCRX at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held BCRX in Q1 2026 and reported no position in Q2 2026.
Institution	Shares sold	Value in Q1 2026
Royalty Pharma Sub-Manager3,846,154 sh	3,846,154	$36.6M
RFG Advisory2,870,700 sh	2,870,700	$27.3M
JACOBS LEVY EQUITY MANAGEMENT1,004,373 sh	1,004,373	$9.6M
Hillsdale Investment Management639,100 sh	639,100	$6.1M
Capricorn Fund Managers Ltd202,900 sh	202,900	$1.9M
BALYASNY ASSET MANAGEMENT L.P.186,125 sh	186,125	$1.8M
UNIVERSITY OF TEXAS/TEXAS AM INVESTMENT MANAGEMENT90,977 sh	90,977	$866.1K
PANAGORA ASSET MANAGEMENT88,876 sh	88,876	$846.1K
Legato Capital Management87,010 sh	87,010	$828.3K
Weiss Asset Management82,100 sh	82,100	$781.6K
DARK FOREST CAPITAL MANAGEMENT78,103 sh	78,103	$743.5K
Entropy Technologies75,908 sh	75,908	$722.6K
Integrated Quantitative Investments65,365 sh	65,365	$622.3K
Vinva Investment Management Ltd40,321 sh	40,321	$555.8K
NAVELLIER & ASSOCIATES45,286 sh	45,286	$431.1K
SummitTX Capital, L.P.41,165 sh	41,165	$391.9K
Bridgefront Capital40,889 sh	40,889	$389.3K
CAPSTONE INVESTMENT ADVISORS29,554 sh	29,554	$281.4K
Vontobel Holding Ltd.27,000 sh	27,000	$257.0K
FARALLON CAPITAL MANAGEMENT24,000 sh	24,000	$228.5K
BENDER ROBERT & ASSOCIATES23,710 sh	23,710	$225.7K
Deeter Investments LLP23,600 sh	23,600	$224.7K
Polymer Capital Management (US)21,353 sh	21,353	$203.3K
SG Americas Securities20,649 sh	20,649	$197.0K
CAXTON ASSOCIATES LLP20,567 sh	20,567	$195.8K
nVerses Capital20,422 sh	20,422	$194.4K
AVIVA PLC15,695 sh	15,695	$149.4K
MIRABELLA FINANCIAL SERVICES LLP14,908 sh	14,908	$141.9K
Blueshift Asset Management11,654 sh	11,654	$110.9K
Hilltop10,310 sh	10,310	$98.2K
QUADRANT CAPITAL GROUP1,410 sh	1,410	$55.7K
1620 INVESTMENT ADVISORS1,180 sh	1,180	$11.2K
Root Financial Partners699 sh	699	$6.7K
Advisory Services Network428 sh	428	$4.1K
Sound Income Strategies427 sh	427	$4.0K
Optiver Holding B.V.302 sh	302	$2.9K
TWIN PEAKS WEALTH ADVISORS20 sh	20	$190.00
Aster Capital Management (DIFC) Ltd6 sh	6	$45.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.