ARDELYX, INC. (ARDX) — Institutional Holders, Q2 2026
250 institutional investment managers reported a ARDX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $904.8M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
ARDX in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- Rubric Capital ManagementAdded · +14,341,804 sh+$73.1M
- AIGH Capital ManagementNew · +3,200,000 sh+$16.3M
- BlackRockAdded · +2,340,498 sh+$11.9M
- NOMURA ASSET MANAGEMENT INTERNATIONALAdded · +1,377,363 sh+$7.0M
- VANGUARD PORTFOLIO MANAGEMENTAdded · +1,365,081 sh+$7.0M
Biggest sellers
- MILLENNIUM MANAGEMENTTrimmed · -3,941,597 sh-$20.1M
- Point72 Asset Management, L.P.Sold out · -2,984,261 sh-$15.2M
- CITADEL ADVISORSTrimmed · -2,434,600 sh-$12.4M
- Freestone Grove PartnersTrimmed · -1,626,091 sh-$8.3M
- MARSHALL WACE, LLPTrimmed · -1,544,362 sh-$7.9M
ARDX 13F holders ranked 1–100 of 250
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | BlackRock#1 · 23,504,630 sh | 23,504,630 | $119.9M | <0.01% | +11.1% |
| 2 | Rubric Capital Management#2 · 16,202,700 sh | 16,202,700 | $82.6M | 0.76% | +770.7% |
| 3 | MILLENNIUM MANAGEMENT#3 · 13,900,773 sh | 13,900,773 | $70.9M | 0.03% | -22.1% |
| 4 | STATE STREET#4 · 13,356,128 sh | 13,356,128 | $68.1M | <0.01% | -1.8% |
| 5 | VANGUARD CAPITAL MANAGEMENT#5 · 10,471,494 sh | 10,471,494 | $53.4M | <0.01% | +1.0% |
| 6 | NOMURA ASSET MANAGEMENT INTERNATIONAL#6 · 9,546,732 sh | 9,546,732 | $48.7M | 0.07% | +16.9% |
| 7 | VANGUARD PORTFOLIO MANAGEMENT#7 · 8,026,774 sh | 8,026,774 | $40.9M | <0.01% | +20.5% |
| 8 | GEODE CAPITAL MANAGEMENT#8 · 6,401,736 sh | 6,401,736 | $32.7M | <0.01% | +6.6% |
| 9 | Jupiter Topco#9 · 5,302,311 sh | 5,302,311 | $27.0M | 0.01% | — |
| 10 | TWO SIGMA INVESTMENTS#10 · 5,209,823 sh | 5,209,823 | $26.6M | 0.02% | +21.9% |
| 11 | Nuveen#11 · 3,997,099 sh | 3,997,099 | $20.4M | <0.01% | -23.6% |
| 12 | GOLDMAN SACHS GROUP#12 · 3,685,034 sh | 3,685,034 | $18.8M | <0.01% | +14.6% |
| 13 | AIGH Capital Management#13 · 3,200,000 sh | 3,200,000 | $16.3M | 1.03% | New |
| 14 | MORGAN STANLEY#14 · 2,389,546 sh | 2,389,546 | $12.2M | <0.01% | +39.8% |
| 15 | AQR CAPITAL MANAGEMENT#15 · 2,316,220 sh | 2,316,220 | $11.8M | <0.01% | -5.1% |
| 16 | NORTHERN#16 · 2,280,143 sh | 2,280,143 | $11.6M | <0.01% | +10.1% |
| 17 | Rock Springs Capital Management#17 · 2,241,769 sh | 2,241,769 | $11.4M | 0.56% | -2.5% |
| 18 | CHARLES SCHWAB INVESTMENT MANAGEMENT#18 · 2,211,760 sh | 2,211,760 | $11.3M | <0.01% | +4.6% |
| 19 | BANK OF AMERICA#19 · 2,163,500 sh | 2,163,500 | $11.0M | <0.01% | -7.4% |
| 20 | Qube Research & Technologies Ltd#20 · 2,090,675 sh | 2,090,675 | $10.7M | <0.01% | -14.2% |
| 21 | JONES FINANCIAL COMPANIES LLLP#21 · 1,765,932 sh | 1,765,932 | $9.8M | <0.01% | -5.0% |
| 22 | VANGUARD FIDUCIARY#22 · 1,754,819 sh | 1,754,819 | $8.9M | <0.01% | +4.6% |
| 23 | Eversept Partners#23 · 1,678,345 sh | 1,678,345 | $8.6M | 0.44% | -24.7% |
| 24 | J. Goldman#24 · 1,579,828 sh | 1,579,828 | $8.1M | 0.21% | -47.3% |
| 25 | Invesco Ltd.#25 · 1,368,868 sh | 1,368,868 | $7.0M | <0.01% | +337.7% |
| 26 | FIRST ADVISORS#26 · 1,301,624 sh | 1,301,624 | $6.6M | <0.01% | -13.2% |
| 27 | Hennion & Walsh Asset Management#27 · 1,211,690 sh | 1,211,690 | $6.2M | — | +21.0% |
| 28 | SCHRODER INVESTMENT MANAGEMENT GROUP#28 · 1,161,238 sh | 1,161,238 | $6.1M | <0.01% | +176.6% |
| 29 | CITADEL ADVISORS#29 · 1,030,174 sh | 1,030,174 | $5.3M | <0.01% | -70.3% |
| 30 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#30 · 916,037 sh | 916,037 | $4.7M | <0.01% | +30.5% |
| 31 | RENAISSANCE TECHNOLOGIES#31 · 892,593 sh | 892,593 | $4.6M | <0.01% | -29.9% |
| 32 | PANAGORA ASSET MANAGEMENT#32 · 890,944 sh | 890,944 | $4.5M | 0.01% | New |
| 33 | BNP PARIBAS FINANCIAL MARKETS#33 · 810,322 sh | 810,322 | $4.1M | <0.01% | +16.0% |
| 34 | DEUTSCHE BANK AG\#34 · 770,910 sh | 770,910 | $3.9M | <0.01% | +8.8% |
| 35 | ExodusPoint Capital Management#35 · 752,923 sh | 752,923 | $3.8M | 0.02% | New |
| 36 | Bank of New York Mellon#36 · 749,676 sh | 749,676 | $3.8M | <0.01% | +7.0% |
| 37 | Squarepoint Ops#37 · 715,262 sh | 715,262 | $3.6M | <0.01% | +2.6% |
| 38 | SECTOR GAMMA AS#38 · 686,844 sh | 686,844 | $3.5M | 0.76% | +33.1% |
| 39 | Trexquant Investment#39 · 660,586 sh | 660,586 | $3.4M | 0.02% | -17.9% |
| 40 | Redmile Group#40 · 641,750 sh | 641,750 | $3.3M | 0.22% | -12.5% |
| 41 | RAYMOND JAMES FINANCIAL#41 · 562,672 sh | 562,672 | $2.9M | <0.01% | +15.6% |
| 42 | UBS Group AG#42 · 551,721 sh | 551,721 | $2.8M | <0.01% | -19.9% |
| 43 | Jump Financial#43 · 536,981 sh | 536,981 | $2.7M | 0.02% | New |
| 44 | Krensavage Asset Management#44 · 534,523 sh | 534,523 | $2.7M | 1.04% | +6.9% |
| 45 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#45 · 486,412 sh | 486,412 | $2.5M | <0.01% | +10.4% |
| 46 | MACKENZIE FINANCIAL#46 · 474,094 sh | 474,094 | $2.4M | <0.01% | New |
| 47 | Swiss National Bank#47 · 467,600 sh | 467,600 | $2.4M | <0.01% | -2.7% |
| 48 | HUSSMAN STRATEGIC ADVISORS#48 · 420,000 sh | 420,000 | $2.1M | 0.49% | New |
| 49 | Universal- Beteiligungs- und Servicegesellschaft mbH#49 · 411,386 sh | 411,386 | $2.1M | <0.01% | +15.2% |
| 50 | PRICE T ROWE ASSOCIATES#50 · 359,635 sh | 359,635 | $1.8M | <0.01% | +22.4% |
| 51 | Clay Northam Wealth Management#51 · 334,115 sh | 334,115 | $1.7M | — | +0.6% |
| 52 | CITIGROUP#52 · 311,021 sh | 311,021 | $1.6M | <0.01% | +370.3% |
| 53 | ALLIANCEBERNSTEIN L.P.#53 · 264,770 sh | 264,770 | $1.6M | <0.01% | 0.0% |
| 54 | Raiffeisen Bank International AG#54 · 300,000 sh | 300,000 | $1.6M | 0.02% | 0.0% |
| 55 | RHUMBLINE ADVISERS#55 · 305,800 sh | 305,800 | $1.6M | <0.01% | +4.8% |
| 56 | DIADEMA PARTNERS#56 · 303,025 sh | 303,025 | $1.5M | 0.20% | New |
| 57 | Y-Intercept (Hong Kong) Ltd#57 · 290,254 sh | 290,254 | $1.5M | — | -35.6% |
| 58 | WELLS FARGO & COMPANY#58 · 280,470 sh | 280,470 | $1.4M | <0.01% | +96.1% |
| 59 | Knott David M Jr#59 · 263,168 sh | 263,168 | $1.3M | 0.71% | +27.1% |
| 60 | Freestone Grove Partners#60 · 253,692 sh | 253,692 | $1.3M | <0.01% | -86.5% |
| 61 | JPMORGAN CHASE#61 · 225,800 sh | 225,800 | $1.2M | <0.01% | -47.5% |
| 62 | IEQ CAPITAL#62 · 240,798 sh | 240,798 | $1.2M | <0.01% | -18.5% |
| 63 | Headlands Technologies#63 · 240,796 sh | 240,796 | $1.2M | 0.13% | +8.2% |
| 64 | Pekin Hardy Strauss#64 · 226,400 sh | 226,400 | $1.2M | 0.10% | -11.5% |
| 65 | LPL Financial#65 · 210,612 sh | 210,612 | $1.1M | <0.01% | -0.3% |
| 66 | THRIVENT FINANCIAL FOR LUTHERANS#66 · 210,555 sh | 210,555 | $1.1M | <0.01% | +7.3% |
| 67 | Rafferty Asset Management#67 · 206,163 sh | 206,163 | $1.1M | <0.01% | -49.5% |
| 68 | Virtus Investment Advisers#68 · 204,373 sh | 204,373 | $1.0M | 0.24% | +50.3% |
| 69 | FRANKLIN RESOURCES#69 · 201,445 sh | 201,445 | $1.0M | <0.01% | +8.7% |
| 70 | MONIMUS CAPITAL MANAGEMENT#70 · 195,611 sh | 195,611 | $997.6K | 0.23% | -55.9% |
| 71 | Legal & General Group Plc#71 · 195,464 sh | 195,464 | $996.9K | <0.01% | -5.4% |
| 72 | Carrera Capital Advisors#72 · 195,159 sh | 195,159 | $995.3K | 0.15% | +2.1% |
| 73 | Walleye Capital#73 · 171,014 sh | 171,014 | $872.2K | <0.01% | New |
| 74 | VANGUARD ASSET MANAGEMENT, Ltd#74 · 166,521 sh | 166,521 | $849.3K | <0.01% | 0.0% |
| 75 | SEI INVESTMENTS#75 · 152,059 sh | 152,059 | $775.5K | <0.01% | +13.1% |
| 76 | SIMPLEX TRADING#76 · 151,427 sh | 151,427 | $772.3K | <0.01% | -13.4% |
| 77 | STATE OF WISCONSIN INVESTMENT BOARD#77 · 143,425 sh | 143,425 | $731.5K | <0.01% | -10.2% |
| 78 | MetLife Investment Management#78 · 142,652 sh | 142,652 | $727.5K | <0.01% | +7.3% |
| 79 | PFG Investments#79 · 137,660 sh | 137,660 | $702.1K | 0.03% | -0.1% |
| 80 | MIRAE ASSET GLOBAL ETFS Ltd.#80 · 136,512 sh | 136,512 | $699.3K | <0.01% | -3.4% |
| 81 | Inspire Investing#81 · 134,251 sh | 134,251 | $684.7K | — | +54.6% |
| 82 | Caption Management#82 · 130,000 sh | 130,000 | $663.0K | <0.01% | +24.8% |
| 83 | LOS ANGELES CAPITAL MANAGEMENT#83 · 129,367 sh | 129,367 | $659.8K | <0.01% | New |
| 84 | Lion Point Capital#84 · 128,650 sh | 128,650 | $656.1K | 3.14% | 0.0% |
| 85 | SECTORAL ASSET MANAGEMENT#85 · 122,394 sh | 122,394 | $624.2K | 0.44% | 0.0% |
| 86 | Trust Co#86 · 116,369 sh | 116,369 | $593.5K | — | New |
| 87 | DekaBank Deutsche Girozentrale#87 · 100,000 sh | 100,000 | $591.0K | — | 0.0% |
| 88 | PRUDENTIAL FINANCIAL#88 · 115,790 sh | 115,790 | $590.5K | <0.01% | +3.0% |
| 89 | Pavaki Capital Management#89 · 115,000 sh | 115,000 | $586.5K | — | 0.0% |
| 90 | Vanguard Global Advisers#90 · 112,904 sh | 112,904 | $575.8K | <0.01% | 0.0% |
| 91 | GROUP ONE TRADING, L.P.#91 · 105,903 sh | 105,903 | $540.1K | <0.01% | -12.0% |
| 92 | PROFUND ADVISORS#92 · 105,338 sh | 105,338 | $537.2K | 0.01% | -42.1% |
| 93 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#93 · 104,922 sh | 104,922 | $535.1K | <0.01% | -2.1% |
| 94 | Zurcher Kantonalbank (Zurich Cantonalbank)#94 · 103,494 sh | 103,494 | $527.8K | <0.01% | 0.0% |
| 95 | SG Americas Securities#95 · 103,174 sh | 103,174 | $526.0K | <0.01% | -3.4% |
| 96 | Russell Investments Group, Ltd.#96 · 102,617 sh | 102,617 | $523.3K | <0.01% | +82.3% |
| 97 | HSBC PLC#97 · 100,550 sh | 100,550 | $509.3K | <0.01% | +7.0% |
| 98 | ACADIAN ASSET MANAGEMENT#98 · 97,921 sh | 97,921 | $497.0K | <0.01% | -15.1% |
| 99 | Diversified#99 · 97,247 sh | 97,247 | $496.0K | <0.01% | New |
| 100 | WELLINGTON MANAGEMENT GROUP LLP#100 · 90,358 sh | 90,358 | $460.8K | <0.01% | -5.1% |
Funds that sold out of ARDX in Q2 2026 (34)
Held ARDX at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Point72 Asset Management, L.P.2,984,261 sh | 2,984,261 | $17.9M |
| JANE STREET GROUP1,179,379 sh | 1,179,379 | $7.1M |
| Ishara Investments451,000 sh | 451,000 | $2.7M |
| HRT FINANCIAL325,124 sh | 325,124 | $1.9M |
| CAPITAL FUND MANAGEMENT S.A.165,498 sh | 165,498 | $991.3K |
| TUDOR INVESTMENT ET AL101,378 sh | 101,378 | $607.3K |
| Man Group plc79,602 sh | 79,602 | $476.8K |
| Brevan Howard Capital Management74,100 sh | 74,100 | $443.9K |
| Vise Technologies57,638 sh | 57,638 | $336.0K |
| Virtu Financial56,057 sh | 56,057 | $336.0K |
| AXQ CAPITAL41,421 sh | 41,421 | $248.1K |
| Schonfeld Strategic Advisors39,299 sh | 39,299 | $235.4K |
| VIRGINIA RETIREMENT SYSTEMS ET Al34,550 sh | 34,550 | $207.0K |
| Lighthouse Investment Partners33,706 sh | 33,706 | $201.9K |
| LightSquare Wealth Management28,229 sh | 28,229 | $169.1K |
| Leonteq Securities AG18,000 sh | 18,000 | $142.7K |
| Entropy Technologies23,145 sh | 23,145 | $138.6K |
| FARALLON CAPITAL MANAGEMENT23,000 sh | 23,000 | $137.8K |
| Scientech Research17,799 sh | 17,799 | $106.6K |
| Vontobel Holding Ltd.16,470 sh | 16,470 | $98.7K |
| Orion Porfolio Solutions15,777 sh | 15,777 | $94.5K |
| Susquehanna Portfolio Strategies14,396 sh | 14,396 | $86.2K |
| Gotham Asset Management13,455 sh | 13,455 | $80.6K |
| Richmond Investment Services12,000 sh | 12,000 | $71.9K |
| Krilogy Financial11,124 sh | 11,124 | $69.9K |
| Vanguard Personalized Indexing Management10,810 sh | 10,810 | $64.8K |
| Sumitomo Mitsui10,320 sh | 10,320 | $61.8K |
| Focus Partners Advisor Solutions10,264 sh | 10,264 | $61.5K |
| MAI Capital Management5,987 sh | 5,987 | $35.9K |
| Sound Income Strategies1,399 sh | 1,399 | $8.5K |
| Aventura Private Wealth672 sh | 672 | $4.0K |
| Aster Capital Management (DIFC) Ltd509 sh | 509 | $2.5K |
| CoreCap Advisors200 sh | 200 | $1.2K |
| Versant Capital Management34 sh | 34 | $204.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.