Annexon, Inc. (ANNX) — Institutional Holders, Q2 2026
217 institutional investment managers reported a ANNX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $1.0B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
ANNX in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- FMRAdded · +8,882,848 sh+$50.7M
- Woodline PartnersAdded · +4,587,930 sh+$26.2M
- GOLDMAN SACHS GROUPAdded · +3,672,699 sh+$21.0M
- MPM BioImpactNew · +3,544,354 sh+$20.2M
- STATE STREETAdded · +2,905,066 sh+$16.6M
Biggest sellers
- BANK OF AMERICATrimmed · -3,645,809 sh-$20.8M
- Redmile GroupTrimmed · -2,679,891 sh-$15.3M
- NuveenTrimmed · -1,481,250 sh-$8.5M
- Bellevue Group AGTrimmed · -1,057,274 sh-$6.0M
- BALYASNY ASSET MANAGEMENT L.P.Trimmed · -1,055,933 sh-$6.0M
ANNX 13F holders ranked 1–100 of 217
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | FMR#1 · 19,518,496 sh | 19,518,496 | $111.5M | <0.01% | +83.5% |
| 2 | BlackRock#2 · 13,539,744 sh | 13,539,744 | $77.3M | <0.01% | +23.8% |
| 3 | Redmile Group#3 · 11,869,877 sh | 11,869,877 | $67.8M | 4.55% | -18.4% |
| 4 | STATE STREET#4 · 9,824,321 sh | 9,824,321 | $56.1M | <0.01% | +42.0% |
| 5 | BVF#5 · 8,698,173 sh | 8,698,173 | $49.7M | 1.27% | 0.0% |
| 6 | Woodline Partners#6 · 6,925,067 sh | 6,925,067 | $39.5M | 0.12% | +196.3% |
| 7 | VANGUARD CAPITAL MANAGEMENT#7 · 6,871,015 sh | 6,871,015 | $39.2M | <0.01% | +15.4% |
| 8 | MAK CAPITAL ONE#8 · 5,862,180 sh | 5,862,180 | $33.5M | 4.69% | +24.1% |
| 9 | GOLDMAN SACHS GROUP#9 · 5,825,579 sh | 5,825,579 | $33.3M | <0.01% | +170.6% |
| 10 | Siren, L.L.C.#10 · 4,458,646 sh | 4,458,646 | $25.5M | 0.52% | +12.6% |
| 11 | Bain Capital Life Sciences Investors#11 · 4,437,731 sh | 4,437,731 | $25.3M | 1.51% | -14.9% |
| 12 | Bellevue Group AG#12 · 4,100,016 sh | 4,100,016 | $23.4M | 0.49% | -20.5% |
| 13 | GEODE CAPITAL MANAGEMENT#13 · 4,037,193 sh | 4,037,193 | $23.1M | <0.01% | +19.5% |
| 14 | MPM BioImpact#14 · 3,544,354 sh | 3,544,354 | $20.2M | 1.23% | New |
| 15 | AMERIPRISE FINANCIAL#15 · 3,509,623 sh | 3,509,623 | $20.0M | <0.01% | +1.8% |
| 16 | ADAGE CAPITAL PARTNERS GP, L.L.C.#16 · 3,500,000 sh | 3,500,000 | $20.0M | 0.03% | -18.6% |
| 17 | GREAT POINT PARTNERS#17 · 3,500,000 sh | 3,500,000 | $20.0M | 3.78% | +40.0% |
| 18 | MORGAN STANLEY#18 · 3,144,453 sh | 3,144,453 | $18.0M | <0.01% | +14.9% |
| 19 | Palo Alto Investors#19 · 2,948,090 sh | 2,948,090 | $16.8M | 2.33% | 0.0% |
| 20 | BALYASNY ASSET MANAGEMENT L.P.#20 · 2,830,976 sh | 2,830,976 | $16.2M | 0.02% | -27.2% |
| 21 | Nuveen#21 · 2,765,080 sh | 2,765,080 | $15.8M | <0.01% | -34.9% |
| 22 | Qube Research & Technologies Ltd#22 · 2,749,961 sh | 2,749,961 | $15.7M | 0.01% | -11.7% |
| 23 | VANGUARD PORTFOLIO MANAGEMENT#23 · 2,246,800 sh | 2,246,800 | $12.8M | <0.01% | +51.5% |
| 24 | Opaleye Management#24 · 1,714,451 sh | 1,714,451 | $9.8M | 0.89% | -26.5% |
| 25 | Logos Global Management#25 · 1,500,000 sh | 1,500,000 | $8.6M | 0.37% | New |
| 26 | DIMENSIONAL FUND ADVISORS#26 · 1,497,756 sh | 1,497,756 | $8.6M | <0.01% | +62.1% |
| 27 | Point72 Asset Management, L.P.#27 · 1,382,699 sh | 1,382,699 | $7.9M | <0.01% | -26.1% |
| 28 | NORTHERN#28 · 1,352,046 sh | 1,352,046 | $7.7M | <0.01% | +24.4% |
| 29 | CHARLES SCHWAB INVESTMENT MANAGEMENT#29 · 1,257,799 sh | 1,257,799 | $7.2M | <0.01% | +14.1% |
| 30 | TFG Asset Management GP Ltd#30 · 1,242,455 sh | 1,242,455 | $7.1M | 1.12% | -3.9% |
| 31 | Candriam S.C.A.#31 · 1,195,142 sh | 1,195,142 | $6.8M | 0.03% | New |
| 32 | MILLENNIUM MANAGEMENT#32 · 1,184,931 sh | 1,184,931 | $6.8M | <0.01% | -4.3% |
| 33 | VANGUARD FIDUCIARY#33 · 1,105,450 sh | 1,105,450 | $6.3M | <0.01% | +24.4% |
| 34 | MASSACHUSETTS FINANCIAL SERVICES#34 · 1,037,366 sh | 1,037,366 | $5.9M | <0.01% | +14.8% |
| 35 | JPMORGAN CHASE#35 · 1,004,308 sh | 1,004,308 | $5.6M | <0.01% | +210.1% |
| 36 | WELLS FARGO & COMPANY#36 · 978,055 sh | 978,055 | $5.6M | <0.01% | +40.0% |
| 37 | PANAGORA ASSET MANAGEMENT#37 · 967,926 sh | 967,926 | $5.5M | 0.02% | New |
| 38 | KENNEDY CAPITAL MANAGEMENT#38 · 898,394 sh | 898,394 | $5.1M | 0.09% | -1.5% |
| 39 | Ishara Investments#39 · 820,000 sh | 820,000 | $4.7M | 3.44% | +370.6% |
| 40 | Ensign Peak Advisors#40 · 800,516 sh | 800,516 | $4.6M | <0.01% | +28.1% |
| 41 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP#41 · 737,935 sh | 737,935 | $4.2M | <0.01% | New |
| 42 | Y-Intercept (Hong Kong) Ltd#42 · 734,585 sh | 734,585 | $4.2M | — | -44.3% |
| 43 | Russell Investments Group, Ltd.#43 · 705,291 sh | 705,291 | $4.0M | <0.01% | -0.9% |
| 44 | AQR CAPITAL MANAGEMENT#44 · 691,812 sh | 691,812 | $4.0M | <0.01% | -11.0% |
| 45 | Parkman Healthcare Partners#45 · 641,029 sh | 641,029 | $3.7M | 0.37% | -4.9% |
| 46 | ACADIAN ASSET MANAGEMENT#46 · 629,127 sh | 629,127 | $3.6M | <0.01% | -17.0% |
| 47 | UBS Group AG#47 · 623,094 sh | 623,094 | $3.6M | <0.01% | -50.0% |
| 48 | DEUTSCHE BANK AG\#48 · 616,489 sh | 616,489 | $3.5M | <0.01% | +9.7% |
| 49 | BANK OF AMERICA#49 · 614,186 sh | 614,186 | $3.5M | <0.01% | -85.6% |
| 50 | CITADEL ADVISORS#50 · 596,582 sh | 596,582 | $3.4M | <0.01% | -0.6% |
| 51 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)#51 · 583,913 sh | 583,913 | $3.3M | 0.03% | 0.0% |
| 52 | SIRIOS CAPITAL MANAGEMENT L P#52 · 569,276 sh | 569,276 | $3.3M | 0.40% | -1.0% |
| 53 | Schonfeld Strategic Advisors#53 · 533,567 sh | 533,567 | $3.0M | 0.01% | +332.8% |
| 54 | TWO SIGMA INVESTMENTS#54 · 512,796 sh | 512,796 | $2.9M | <0.01% | +8.8% |
| 55 | Hennion & Walsh Asset Management#55 · 507,050 sh | 507,050 | $2.9M | — | -0.5% |
| 56 | Bank of New York Mellon#56 · 501,442 sh | 501,442 | $2.9M | <0.01% | +26.9% |
| 57 | Board of Trustees of The Leland Stanford Junior University#57 · 482,550 sh | 482,550 | $2.8M | 0.52% | 0.0% |
| 58 | RENAISSANCE TECHNOLOGIES#58 · 459,000 sh | 459,000 | $2.6M | <0.01% | -15.7% |
| 59 | Ikarian Capital#59 · 430,244 sh | 430,244 | $2.5M | 0.26% | -25.9% |
| 60 | MOORE CAPITAL MANAGEMENT#60 · 425,332 sh | 425,332 | $2.4M | 0.04% | New |
| 61 | Trexquant Investment#61 · 409,667 sh | 409,667 | $2.3M | 0.01% | +1.5% |
| 62 | WELLINGTON MANAGEMENT GROUP LLP#62 · 406,795 sh | 406,795 | $2.3M | <0.01% | -22.0% |
| 63 | Susquehanna Portfolio Strategies#63 · 395,230 sh | 395,230 | $2.3M | 0.04% | +9.7% |
| 64 | MUTUAL OF AMERICA CAPITAL MANAGEMENT#64 · 394,600 sh | 394,600 | $2.3M | — | -5.3% |
| 65 | Invesco Ltd.#65 · 330,729 sh | 330,729 | $1.9M | <0.01% | -56.7% |
| 66 | Engineers Gate Manager#66 · 319,057 sh | 319,057 | $1.8M | 0.02% | +83.2% |
| 67 | DAFNA Capital Management#67 · 297,812 sh | 297,812 | $1.7M | 0.32% | +152.8% |
| 68 | Jump Financial#68 · 297,800 sh | 297,800 | $1.7M | 0.01% | New |
| 69 | STATE OF WISCONSIN INVESTMENT BOARD#69 · 286,375 sh | 286,375 | $1.6M | <0.01% | +475.7% |
| 70 | D. E. Shaw#70 · 265,284 sh | 265,284 | $1.5M | <0.01% | -62.3% |
| 71 | VOLORIDGE INVESTMENT MANAGEMENT#71 · 250,025 sh | 250,025 | $1.4M | <0.01% | -45.9% |
| 72 | Swiss National Bank#72 · 244,600 sh | 244,600 | $1.4M | <0.01% | +3.6% |
| 73 | CITIGROUP#73 · 235,990 sh | 235,990 | $1.3M | <0.01% | +665.8% |
| 74 | Cinctive Capital Management#74 · 215,748 sh | 215,748 | $1.2M | 0.05% | -19.7% |
| 75 | MARSHALL WACE, LLP#75 · 210,607 sh | 210,607 | $1.2M | <0.01% | -75.6% |
| 76 | RHUMBLINE ADVISERS#76 · 189,578 sh | 189,578 | $1.1M | <0.01% | +18.7% |
| 77 | SEI INVESTMENTS#77 · 183,817 sh | 183,817 | $1.0M | <0.01% | -9.6% |
| 78 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#78 · 180,647 sh | 180,647 | $1.0M | <0.01% | +38.3% |
| 79 | Squarepoint Ops#79 · 173,285 sh | 173,285 | $989.5K | <0.01% | +155.0% |
| 80 | Rafferty Asset Management#80 · 173,279 sh | 173,279 | $989.4K | <0.01% | -14.8% |
| 81 | OSAIC#81 · 147,624 sh | 147,624 | $842.9K | <0.01% | New |
| 82 | ALLIANCEBERNSTEIN L.P.#82 · 147,240 sh | 147,240 | $815.7K | <0.01% | +23.7% |
| 83 | PRICE T ROWE ASSOCIATES#83 · 129,243 sh | 129,243 | $738.0K | <0.01% | -69.9% |
| 84 | VICTORY CAPITAL MANAGEMENT#84 · 127,338 sh | 127,338 | $727.1K | <0.01% | +10.2% |
| 85 | BOOTHBAY FUND MANAGEMENT#85 · 120,129 sh | 120,129 | $685.9K | <0.01% | -27.7% |
| 86 | IEQ CAPITAL#86 · 120,010 sh | 120,010 | $685.3K | <0.01% | -38.7% |
| 87 | J. Goldman#87 · 116,046 sh | 116,046 | $662.6K | 0.02% | -32.1% |
| 88 | XTX Topco Ltd#88 · 112,147 sh | 112,147 | $640.4K | <0.01% | +39.3% |
| 89 | VIRGINIA RETIREMENT SYSTEMS ET Al#89 · 108,600 sh | 108,600 | $620.1K | <0.01% | New |
| 90 | GSA CAPITAL PARTNERS LLP#90 · 104,378 sh | 104,378 | $596.0K | 0.04% | +229.3% |
| 91 | Vanguard Global Advisers#91 · 102,067 sh | 102,067 | $582.8K | <0.01% | +88.8% |
| 92 | Quarry#92 · 100,000 sh | 100,000 | $571.0K | 0.05% | +370.6% |
| 93 | SCS Capital Management#93 · 99,000 sh | 99,000 | $565.3K | <0.01% | 0.0% |
| 94 | Legal & General Group Plc#94 · 98,118 sh | 98,118 | $560.3K | <0.01% | +22.6% |
| 95 | MIRAE ASSET GLOBAL ETFS Ltd.#95 · 91,661 sh | 91,661 | $520.6K | <0.01% | +20.2% |
| 96 | MetLife Investment Management#96 · 91,005 sh | 91,005 | $519.6K | <0.01% | +25.6% |
| 97 | J. Safra Sarasin Holding AG#97 · 90,487 sh | 90,487 | $516.7K | — | 0.0% |
| 98 | Zurcher Kantonalbank (Zurich Cantonalbank)#98 · 88,518 sh | 88,518 | $505.4K | <0.01% | +64.3% |
| 99 | CAPTRUST FINANCIAL ADVISORS#99 · 87,909 sh | 87,909 | $502.0K | <0.01% | +11.0% |
| 100 | PROFUND ADVISORS#100 · 87,509 sh | 87,509 | $499.7K | 0.01% | -3.8% |
Funds that sold out of ANNX in Q2 2026 (27)
Held ANNX at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| Longaeva Partners L.P.620,401 sh | 620,401 | $3.4M |
| SILVERARC CAPITAL MANAGEMENT496,461 sh | 496,461 | $2.8M |
| Rosalind Advisors200,000 sh | 200,000 | $1.1M |
| ALGERT GLOBAL154,840 sh | 154,840 | $858.0K |
| Man Group plc109,222 sh | 109,222 | $605.1K |
| Connor, Clark & Lunn Investment Management Ltd.92,707 sh | 92,707 | $513.6K |
| POLEN CAPITAL MANAGEMENT70,152 sh | 70,152 | $388.6K |
| AXQ CAPITAL58,185 sh | 58,185 | $322.3K |
| ADAR1 Capital Management55,000 sh | 55,000 | $304.7K |
| BIT Capital GmbH50,000 sh | 50,000 | $277.0K |
| JANE STREET GROUP47,120 sh | 47,120 | $261.0K |
| MIRABELLA FINANCIAL SERVICES LLP28,739 sh | 28,739 | $159.2K |
| Virtu Financial28,450 sh | 28,450 | $158.0K |
| TD ASSET MANAGEMENT22,760 sh | 22,760 | $126.1K |
| Scientech Research17,316 sh | 17,316 | $95.9K |
| ExodusPoint Capital Management14,938 sh | 14,938 | $82.8K |
| Vontobel Holding Ltd.14,511 sh | 14,511 | $80.4K |
| Magnetar Financial14,205 sh | 14,205 | $78.7K |
| AMERICAN CENTURY COMPANIES12,463 sh | 12,463 | $69.0K |
| nVerses Capital11,897 sh | 11,897 | $65.9K |
| Abel Hall10,921 sh | 10,921 | $60.5K |
| MAI Capital Management795 sh | 795 | $4.4K |
| FEDERATED HERMES753 sh | 753 | $4.2K |
| Root Financial Partners94 sh | 94 | $521.00 |
| US BANCORP \DE\77 sh | 77 | $427.00 |
| Advisory Services Network23 sh | 23 | $127.00 |
| JPL Wealth Management13 sh | 13 | $73.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.