ALNYLAM PHARMACEUTICALS, INC. (ALNY) — Institutional Holders, Q2 2026
811 institutional investment managers reported a ALNY position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $40.5B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
ALNY in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- Invesco Ltd.Added · +2,462,592 sh+$741.3M
- Deep Track CapitalNew · +825,000 sh+$248.3M
- Orbis Allan Gray LtdAdded · +652,582 sh+$196.4M
- LOS ANGELES CAPITAL MANAGEMENTAdded · +641,357 sh+$193.1M
- Paradigm Biocapital AdvisorsNew · +480,000 sh+$144.5M
Biggest sellers
- JPMORGAN CHASETrimmed · -3,648,235 sh-$1.1B
- MARSHALL WACE, LLPTrimmed · -839,519 sh-$252.7M
- PRICE T ROWE ASSOCIATESTrimmed · -283,547 sh-$85.4M
- Allspring Global InvestmentsTrimmed · -279,247 sh-$84.1M
- Bellevue Group AGTrimmed · -233,451 sh-$70.3M
ALNY 13F holders ranked 1–100 of 811
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | FMR#1 · 32,137,962 sh | 32,137,962 | $4.5B | 0.20% | -2.7% |
| 2 | Capital World Investors#2 · 12,627,846 sh | 12,627,846 | $3.4B | 0.40% | +16.9% |
| 3 | BlackRock#3 · 18,907,675 sh | 18,907,675 | $3.3B | 0.05% | -30.1% |
| 4 | Capital Research Global Investors#4 · 9,750,699 sh | 9,750,699 | $2.9B | 0.41% | +3.0% |
| 5 | VANGUARD PORTFOLIO MANAGEMENT#5 · 6,538,390 sh | 6,538,390 | $2.0B | 0.09% | +0.7% |
| 6 | VANGUARD CAPITAL MANAGEMENT#6 · 6,029,478 sh | 6,029,478 | $1.8B | 0.04% | +1.4% |
| 7 | T. Rowe Price Investment Management#7 · 5,642,173 sh | 5,642,173 | $1.7B | 1.11% | +8.6% |
| 8 | Invesco Ltd.#8 · 5,254,318 sh | 5,254,318 | $1.1B | 0.09% | +38.6% |
| 9 | STATE STREET#9 · 12,825,689 sh | 12,825,689 | $1.1B | 0.03% | -50.8% |
| 10 | GEODE CAPITAL MANAGEMENT#10 · 2,635,840 sh | 2,635,840 | $791.3M | 0.04% | -0.9% |
| 11 | JPMORGAN CHASE#11 · 5,861,517 sh | 5,861,517 | $789.1M | 0.04% | -20.5% |
| 12 | BAILLIE GIFFORD#12 · 2,439,889 sh | 2,439,889 | $734.5M | 0.67% | -2.2% |
| 13 | NORGES BANK#13 · 2,271,813 sh | 2,271,813 | $683.9M | 0.07% | — |
| 14 | WELLINGTON MANAGEMENT GROUP LLP#14 · 2,110,407 sh | 2,110,407 | $635.3M | 0.11% | +9.0% |
| 15 | Orbis Allan Gray Ltd#15 · 1,987,407 sh | 1,987,407 | $598.3M | 2.06% | +48.9% |
| 16 | DODGE & COX#16 · 1,955,393 sh | 1,955,393 | $588.6M | 0.31% | +1.4% |
| 17 | TWO SIGMA INVESTMENTS#17 · 1,875,937 sh | 1,875,937 | $564.7M | 0.41% | -76.5% |
| 18 | AMERICAN CENTURY COMPANIES#18 · 1,853,956 sh | 1,853,956 | $558.1M | 0.25% | +2.9% |
| 19 | Clearbridge Investments#19 · 1,259,483 sh | 1,259,483 | $379.1M | 0.31% | -7.1% |
| 20 | PRICE T ROWE ASSOCIATES#20 · 1,149,201 sh | 1,149,201 | $345.9M | 0.03% | -19.8% |
| 21 | D. E. Shaw#21 · 1,104,109 sh | 1,104,109 | $332.4M | 0.16% | +4.3% |
| 22 | BANK OF AMERICA#22 · 19,744,476 sh | 19,744,476 | $321.9M | 0.02% | +66.3% |
| 23 | MORGAN STANLEY#23 · 2,752,150 sh | 2,752,150 | $312.8M | 0.02% | -33.2% |
| 24 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#24 · 14,693,795 sh | 14,693,795 | $285.6M | 0.22% | +1.6% |
| 25 | Legal & General Group Plc#25 · 924,561 sh | 924,561 | $278.3M | 0.06% | -1.1% |
| 26 | NORTHERN#26 · 886,900 sh | 886,900 | $267.0M | 0.03% | +3.4% |
| 27 | ROYAL BANK OF CANADA#27 · 875,859 sh | 875,859 | $263.7M | 0.04% | +10.4% |
| 28 | VANGUARD FIDUCIARY#28 · 862,782 sh | 862,782 | $259.7M | 0.06% | +2.6% |
| 29 | Deep Track Capital#29 · 825,000 sh | 825,000 | $248.3M | 3.61% | New |
| 30 | DEUTSCHE BANK AG\#30 · 815,400 sh | 815,400 | $245.5M | 0.07% | +7.1% |
| 31 | Qube Research & Technologies Ltd#31 · 798,715 sh | 798,715 | $240.4M | 0.22% | -4.7% |
| 32 | CHARLES SCHWAB INVESTMENT MANAGEMENT#32 · 755,377 sh | 755,377 | $227.4M | 0.03% | +12.2% |
| 33 | LOS ANGELES CAPITAL MANAGEMENT#33 · 729,635 sh | 729,635 | $219.6M | 0.81% | +726.5% |
| 34 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#34 · 727,848 sh | 727,848 | $219.1M | 0.04% | +7.4% |
| 35 | AQR CAPITAL MANAGEMENT#35 · 728,039 sh | 728,039 | $219.0M | 0.08% | -20.3% |
| 36 | FEDERATED HERMES#36 · 719,905 sh | 719,905 | $216.7M | 0.31% | +4.7% |
| 37 | Amundi#37 · 5,617,471 sh | 5,617,471 | $191.9M | 0.05% | -2.3% |
| 38 | UBS Group AG#38 · 650,004 sh | 650,004 | $188.8M | 0.02% | +35.0% |
| 39 | LOOMIS SAYLES & L P#39 · 580,187 sh | 580,187 | $174.7M | 0.22% | +12.2% |
| 40 | GOLDMAN SACHS GROUP#40 · 948,757 sh | 948,757 | $173.5M | 0.02% | +12.5% |
| 41 | Bank of New York Mellon#41 · 707,071 sh | 707,071 | $148.4M | 0.02% | +0.1% |
| 42 | Polar Capital Plc#42 · 482,751 sh | 482,751 | $145.3M | 0.34% | +87.3% |
| 43 | Paradigm Biocapital Advisors#43 · 480,000 sh | 480,000 | $144.5M | 2.71% | New |
| 44 | FRANKLIN RESOURCES#44 · 2,682,699 sh | 2,682,699 | $137.5M | 0.03% | -0.8% |
| 45 | BNP PARIBAS FINANCIAL MARKETS#45 · 42,589,023 sh | 42,589,023 | $132.5M | 0.05% | +30.6% |
| 46 | FIRST ADVISORS#46 · 421,534 sh | 421,534 | $126.9M | 0.07% | +10.1% |
| 47 | RAYMOND JAMES FINANCIAL#47 · 392,799 sh | 392,799 | $118.2M | 0.03% | -3.5% |
| 48 | DIMENSIONAL FUND ADVISORS#48 · 392,022 sh | 392,022 | $118.0M | 0.02% | +2.0% |
| 49 | Swiss National Bank#49 · 374,080 sh | 374,080 | $112.6M | 0.06% | -3.5% |
| 50 | MASSACHUSETTS FINANCIAL SERVICES#50 · 350,560 sh | 350,560 | $105.5M | 0.03% | -29.3% |
| 51 | CANADA PENSION PLAN INVESTMENT BOARD#51 · 334,246 sh | 334,246 | $100.6M | 0.06% | +60.0% |
| 52 | Sumitomo Mitsui#52 · 325,379 sh | 325,379 | $97.9M | 0.06% | +3.5% |
| 53 | MILLENNIUM MANAGEMENT#53 · 316,001 sh | 316,001 | $95.1M | 0.03% | -29.4% |
| 54 | Nuveen#54 · 315,630 sh | 315,630 | $95.0M | 0.02% | -2.0% |
| 55 | Candriam S.C.A.#55 · 314,512 sh | 314,512 | $94.6M | 0.43% | +40.2% |
| 56 | WELLS FARGO & COMPANY#56 · 974,047 sh | 974,047 | $94.1M | 0.02% | -22.2% |
| 57 | NOMURA ASSET MANAGEMENT INTERNATIONAL#57 · 2,359,193 sh | 2,359,193 | $92.8M | 0.14% | +0.4% |
| 58 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#58 · 294,460 sh | 294,460 | $88.6M | <0.01% | +69.0% |
| 59 | Pictet Asset Management Holding SA#59 · 278,613 sh | 278,613 | $83.3M | 0.08% | +17.1% |
| 60 | GILDER GAGNON HOWE#60 · 269,051 sh | 269,051 | $81.0M | 0.84% | -3.9% |
| 61 | CONGRESS ASSET MANAGEMENT#61 · 265,701 sh | 265,701 | $80.0M | — | -7.0% |
| 62 | MARSHALL WACE, LLP#62 · 259,799 sh | 259,799 | $78.2M | 0.06% | -76.4% |
| 63 | STEELHEAD PARTNERS#63 · 65,000,000 sh | 65,000,000 | $78.2M | 5.57% | +8.3% |
| 64 | VANGUARD ASSET MANAGEMENT, Ltd#64 · 257,710 sh | 257,710 | $77.6M | 0.05% | +17.5% |
| 65 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM#65 · 254,053 sh | 254,053 | $76.5M | 0.04% | +11.4% |
| 66 | CITIGROUP#66 · 6,576,786 sh | 6,576,786 | $76.2M | 0.03% | +11.1% |
| 67 | WESTFIELD CAPITAL MANAGEMENT#67 · 252,383 sh | 252,383 | $76.0M | 0.25% | +2.8% |
| 68 | Korea Investment#68 · 247,660 sh | 247,660 | $74.6M | 0.14% | +23.6% |
| 69 | Woodline Partners#69 · 246,282 sh | 246,282 | $74.1M | 0.23% | +1.0% |
| 70 | AMERIPRISE FINANCIAL#70 · 9,104,601 sh | 9,104,601 | $72.3M | 0.01% | +3694.5% |
| 71 | Squarepoint Ops#71 · 233,999 sh | 233,999 | $70.4M | 0.08% | -45.2% |
| 72 | TD ASSET MANAGEMENT#72 · 233,696 sh | 233,696 | $70.3M | 0.06% | -17.1% |
| 73 | ROYAL LONDON ASSET MANAGEMENT LTD#73 · 213,589 sh | 213,589 | $64.3M | 0.12% | -0.7% |
| 74 | BNP Paribas Asset Management Holding S.A.#74 · 9,711,773 sh | 9,711,773 | $60.0M | 0.06% | -2.2% |
| 75 | Universal- Beteiligungs- und Servicegesellschaft mbH#75 · 10,662,223 sh | 10,662,223 | $59.9M | 0.09% | +27.6% |
| 76 | National Pension Service#76 · 198,295 sh | 198,295 | $59.7M | 0.04% | +7.9% |
| 77 | PINEBRIDGE INVESTMENTS#77 · 195,709 sh | 195,709 | $58.9M | 0.49% | -27.9% |
| 78 | CITADEL ADVISORS#78 · 191,029 sh | 191,029 | $57.5M | <0.01% | +715.8% |
| 79 | Robeco Institutional Asset Management B.V.#79 · 188,084 sh | 188,084 | $56.6M | — | +48.7% |
| 80 | VICTORY CAPITAL MANAGEMENT#80 · 172,842 sh | 172,842 | $52.0M | 0.03% | -11.8% |
| 81 | Man Group plc#81 · 170,907 sh | 170,907 | $51.4M | 0.08% | -26.5% |
| 82 | Mitsubishi UFJ Asset Management , Ltd.#82 · 168,664 sh | 168,664 | $50.8M | 0.03% | +10.8% |
| 83 | RHUMBLINE ADVISERS#83 · 165,579 sh | 165,579 | $49.8M | 0.04% | -15.2% |
| 84 | Life Cycle Investment Partners Ltd#84 · 165,424 sh | 165,424 | $49.8M | 0.23% | -6.8% |
| 85 | CIBC Bancorp USA#85 · 163,733 sh | 163,733 | $49.3M | 0.06% | -3.1% |
| 86 | ANTIPODES PARTNERS Ltd#86 · 163,533 sh | 163,533 | $49.2M | 0.90% | +12.5% |
| 87 | Russell Investments Group, Ltd.#87 · 158,228 sh | 158,228 | $47.5M | 0.04% | +7.2% |
| 88 | CAPITAL FUND MANAGEMENT S.A.#88 · 155,904 sh | 155,904 | $46.9M | 0.21% | +11.3% |
| 89 | Assenagon Asset Management S.A.#89 · 155,695 sh | 155,695 | $46.9M | — | +20.8% |
| 90 | Vinva Investment Management Ltd#90 · 154,972 sh | 154,972 | $45.5M | 0.30% | +323.4% |
| 91 | Hudson Bay Capital Management#91 · 148,720 sh | 148,720 | $44.8M | 0.12% | +271.8% |
| 92 | BARCLAYS PLC#92 · 1,414,518 sh | 1,414,518 | $42.3M | <0.01% | +541.1% |
| 93 | ENVESTNET ASSET MANAGEMENT#93 · 136,395 sh | 136,395 | $41.1M | <0.01% | -20.6% |
| 94 | Jupiter Topco#94 · 135,545 sh | 135,545 | $40.8M | 0.02% | — |
| 95 | LMR Partners LLP#95 · 134,214 sh | 134,214 | $40.4M | 0.15% | +79.8% |
| 96 | ProShare Advisors#96 · 128,514 sh | 128,514 | $38.7M | 0.06% | -26.1% |
| 97 | DekaBank Deutsche Girozentrale#97 · 113,193 sh | 113,193 | $37.3M | 0.06% | 0.0% |
| 98 | SEI INVESTMENTS#98 · 372,960 sh | 372,960 | $37.0M | 0.03% | +6.2% |
| 99 | VOYA INVESTMENT MANAGEMENT#99 · 121,903 sh | 121,903 | $36.7M | 0.03% | -17.9% |
| 100 | SCS Capital Management#100 · 115,549 sh | 115,549 | $34.8M | 0.33% | -22.7% |
Funds that sold out of ALNY in Q2 2026 (80)
Held ALNY at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.