ACADIA PHARMACEUTICALS INC (ACAD) — Institutional Holders, Q2 2026
355 institutional investment managers reported a ACAD position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $4.2B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
ACAD in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- MARSHALL WACE, LLPAdded · +1,688,651 sh+$42.7M
- CITADEL ADVISORSAdded · +1,559,417 sh+$39.5M
- Qube Research & Technologies LtdAdded · +1,496,311 sh+$37.9M
- GOLDMAN SACHS GROUPAdded · +1,022,311 sh+$25.9M
- D. E. ShawAdded · +968,101 sh+$24.5M
Biggest sellers
- FIRST ADVISORSTrimmed · -3,159,482 sh-$79.9M
- Palo Alto InvestorsSold out · -2,872,695 sh-$72.7M
- BRAIDWELLTrimmed · -824,800 sh-$20.9M
- JANE STREET GROUPTrimmed · -690,008 sh-$17.5M
- Woodline PartnersSold out · -676,401 sh-$17.1M
ACAD 13F holders ranked 1–100 of 355
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS#1 · 42,912,904 sh | 42,912,904 | $1.1B | 5.44% | 0.0% |
| 2 | BlackRock#2 · 22,515,173 sh | 22,515,173 | $569.6M | <0.01% | +4.5% |
| 3 | STATE STREET#3 · 9,076,212 sh | 9,076,212 | $229.6M | <0.01% | +8.9% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT#4 · 8,838,450 sh | 8,838,450 | $223.6M | 0.01% | +1.9% |
| 5 | RTW INVESTMENTS#5 · 7,144,524 sh | 7,144,524 | $180.8M | 1.54% | 0.0% |
| 6 | VANGUARD CAPITAL MANAGEMENT#6 · 5,763,750 sh | 5,763,750 | $145.8M | <0.01% | +1.8% |
| 7 | DIMENSIONAL FUND ADVISORS#7 · 3,694,988 sh | 3,694,988 | $93.5M | 0.02% | +17.1% |
| 8 | GEODE CAPITAL MANAGEMENT#8 · 3,358,129 sh | 3,358,129 | $85.0M | <0.01% | -3.1% |
| 9 | GOLDMAN SACHS GROUP#9 · 2,580,115 sh | 2,580,115 | $65.3M | <0.01% | +65.6% |
| 10 | Qube Research & Technologies Ltd#10 · 2,446,610 sh | 2,446,610 | $61.9M | 0.06% | +157.5% |
| 11 | Point72 Asset Management, L.P.#11 · 2,433,168 sh | 2,433,168 | $61.6M | 0.07% | -5.6% |
| 12 | CITADEL ADVISORS#12 · 2,182,177 sh | 2,182,177 | $55.2M | <0.01% | +250.4% |
| 13 | Pictet Asset Management Holding SA#13 · 1,983,198 sh | 1,983,198 | $50.1M | 0.05% | -2.1% |
| 14 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP#14 · 1,969,445 sh | 1,969,445 | $49.8M | 0.02% | +25.5% |
| 15 | MARSHALL WACE, LLP#15 · 1,764,838 sh | 1,764,838 | $44.7M | 0.04% | +2216.5% |
| 16 | D. E. Shaw#16 · 1,697,937 sh | 1,697,937 | $43.0M | 0.02% | +132.6% |
| 17 | BRAIDWELL#17 · 1,646,399 sh | 1,646,399 | $41.7M | 1.54% | -33.4% |
| 18 | NORGES BANK#18 · 1,623,308 sh | 1,623,308 | $41.1M | <0.01% | — |
| 19 | Frazier Life Sciences Management, L.P.#19 · 1,438,198 sh | 1,438,198 | $36.4M | 0.79% | 0.0% |
| 20 | NORTHERN#20 · 1,367,422 sh | 1,367,422 | $34.6M | <0.01% | +7.5% |
| 21 | Nuveen#21 · 1,348,192 sh | 1,348,192 | $34.1M | <0.01% | +30.0% |
| 22 | Artisan Partners Limited Partnership#22 · 1,325,134 sh | 1,325,134 | $33.5M | 0.05% | -0.5% |
| 23 | BANK OF AMERICA#23 · 1,300,385 sh | 1,300,385 | $32.9M | <0.01% | -16.3% |
| 24 | RENAISSANCE TECHNOLOGIES#24 · 1,282,596 sh | 1,282,596 | $32.4M | 0.04% | -25.6% |
| 25 | CHARLES SCHWAB INVESTMENT MANAGEMENT#25 · 1,206,336 sh | 1,206,336 | $30.5M | <0.01% | +2.8% |
| 26 | Allspring Global Investments#26 · 1,132,566 sh | 1,132,566 | $28.5M | 0.04% | +18.6% |
| 27 | Rockefeller Capital Management L.P.#27 · 1,015,420 sh | 1,015,420 | $25.7M | 0.04% | -1.2% |
| 28 | MORGAN STANLEY#28 · 946,639 sh | 946,639 | $23.9M | <0.01% | -13.4% |
| 29 | TWO SIGMA INVESTMENTS#29 · 926,992 sh | 926,992 | $23.5M | 0.02% | +19.6% |
| 30 | VANGUARD FIDUCIARY#30 · 912,370 sh | 912,370 | $23.1M | <0.01% | +4.2% |
| 31 | MASSACHUSETTS FINANCIAL SERVICES#31 · 855,435 sh | 855,435 | $21.6M | <0.01% | -16.1% |
| 32 | Invesco Ltd.#32 · 810,462 sh | 810,462 | $20.5M | <0.01% | -3.1% |
| 33 | PRINCIPAL FINANCIAL GROUP#33 · 789,196 sh | 789,196 | $20.0M | <0.01% | +2.7% |
| 34 | Bank of New York Mellon#34 · 760,629 sh | 760,629 | $19.2M | <0.01% | +3.3% |
| 35 | PANAGORA ASSET MANAGEMENT#35 · 710,906 sh | 710,906 | $18.0M | 0.06% | +3.2% |
| 36 | Fisher Asset Management#36 · 699,230 sh | 699,230 | $17.7M | <0.01% | -4.6% |
| 37 | FRED ALGER MANAGEMENT#37 · 648,611 sh | 648,611 | $16.4M | 0.05% | -49.2% |
| 38 | Allianz Asset Management GmbH#38 · 706,664 sh | 706,664 | $15.7M | 0.01% | 0.0% |
| 39 | RICE HALL JAMES & ASSOCIATES#39 · 618,887 sh | 618,887 | $15.7M | 0.76% | +0.2% |
| 40 | AMERIPRISE FINANCIAL#40 · 606,536 sh | 606,536 | $15.3M | <0.01% | -2.8% |
| 41 | MILLENNIUM MANAGEMENT#41 · 589,924 sh | 589,924 | $14.9M | <0.01% | -16.4% |
| 42 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#42 · 583,852 sh | 583,852 | $14.8M | 0.01% | +2.1% |
| 43 | AQR CAPITAL MANAGEMENT#43 · 522,749 sh | 522,749 | $13.2M | <0.01% | -1.0% |
| 44 | ADAGE CAPITAL PARTNERS GP, L.L.C.#44 · 510,000 sh | 510,000 | $12.9M | 0.02% | +5000.0% |
| 45 | GLENMEDE NA#45 · 488,546 sh | 488,546 | $12.4M | 0.05% | +20.4% |
| 46 | Hudson Bay Capital Management#46 · 465,000 sh | 465,000 | $11.8M | 0.03% | +4.4% |
| 47 | UBS Group AG#47 · 460,053 sh | 460,053 | $11.6M | <0.01% | +2.6% |
| 48 | JUPITER ASSET MANAGEMENT LTD#48 · 458,466 sh | 458,466 | $11.6M | 0.06% | -6.6% |
| 49 | PUBLIC SECTOR PENSION INVESTMENT BOARD#49 · 435,375 sh | 435,375 | $11.0M | 0.03% | -2.8% |
| 50 | MACKENZIE FINANCIAL#50 · 420,825 sh | 420,825 | $10.6M | 0.01% | +315.3% |
| 51 | Ishara Investments#51 · 410,000 sh | 410,000 | $10.4M | 7.62% | +233.3% |
| 52 | BALYASNY ASSET MANAGEMENT L.P.#52 · 388,024 sh | 388,024 | $9.8M | 0.01% | +24.0% |
| 53 | PRUDENTIAL FINANCIAL#53 · 365,125 sh | 365,125 | $9.2M | 0.01% | -5.8% |
| 54 | SPHERA FUNDS MANAGEMENT LTD.#54 · 356,534 sh | 356,534 | $9.0M | 1.18% | +39.2% |
| 55 | Alyeska Investment Group, L.P.#55 · 310,287 sh | 310,287 | $7.9M | 0.02% | New |
| 56 | RHUMBLINE ADVISERS#56 · 302,902 sh | 302,902 | $7.7M | <0.01% | -14.8% |
| 57 | Schonfeld Strategic Advisors#57 · 284,157 sh | 284,157 | $7.2M | 0.03% | New |
| 58 | Edgestream Partners, L.P.#58 · 283,301 sh | 283,301 | $7.2M | 0.21% | +48.1% |
| 59 | Legal & General Group Plc#59 · 282,510 sh | 282,510 | $7.1M | <0.01% | -1.7% |
| 60 | DEUTSCHE BANK AG\#60 · 257,759 sh | 257,759 | $6.5M | <0.01% | -69.3% |
| 61 | Logos Global Management#61 · 250,000 sh | 250,000 | $6.3M | 0.27% | -66.7% |
| 62 | LAZARD ASSET MANAGEMENT#62 · 247,569 sh | 247,569 | $6.3M | <0.01% | +0.5% |
| 63 | FMR#63 · 240,384 sh | 240,384 | $6.1M | <0.01% | -31.4% |
| 64 | JPMORGAN CHASE#64 · 234,706 sh | 234,706 | $6.1M | <0.01% | -10.8% |
| 65 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#65 · 233,329 sh | 233,329 | $5.9M | <0.01% | +12.8% |
| 66 | NORDEA INVESTMENT MANAGEMENT AB#66 · 230,485 sh | 230,485 | $5.9M | <0.01% | +1.0% |
| 67 | Swiss National Bank#67 · 230,904 sh | 230,904 | $5.8M | <0.01% | -1.5% |
| 68 | FRANKLIN RESOURCES#68 · 226,092 sh | 226,092 | $5.7M | <0.01% | -1.7% |
| 69 | VICTORY CAPITAL MANAGEMENT#69 · 214,712 sh | 214,712 | $5.4M | <0.01% | +49.7% |
| 70 | HRT FINANCIAL#70 · 209,929 sh | 209,929 | $5.3M | 0.01% | New |
| 71 | PUBLIC EMPLOYEES RETIREMENT ASSOCIATION OF COLORADO#71 · 208,471 sh | 208,471 | $5.3M | 0.02% | +1408.4% |
| 72 | PRICE T ROWE ASSOCIATES#72 · 207,047 sh | 207,047 | $5.2M | <0.01% | -67.4% |
| 73 | ALPS ADVISORS#73 · 197,049 sh | 197,049 | $5.0M | 0.02% | +21.0% |
| 74 | WELLS FARGO & COMPANY#74 · 195,371 sh | 195,371 | $4.9M | <0.01% | +64.8% |
| 75 | CITIGROUP#75 · 194,948 sh | 194,948 | $4.9M | <0.01% | +188.9% |
| 76 | ENVESTNET ASSET MANAGEMENT#76 · 194,713 sh | 194,713 | $4.9M | <0.01% | +14.6% |
| 77 | FIRST ADVISORS#77 · 184,386 sh | 184,386 | $4.7M | <0.01% | -94.5% |
| 78 | NEW YORK STATE COMMON RETIREMENT FUND#78 · 172,522 sh | 172,522 | $4.4M | <0.01% | +12.7% |
| 79 | Birchview Capital#79 · 171,000 sh | 171,000 | $4.3M | 2.02% | 0.0% |
| 80 | MARTINGALE ASSET MANAGEMENT L P#80 · 167,893 sh | 167,893 | $4.2M | 0.10% | +20.0% |
| 81 | TFG Asset Management GP Ltd#81 · 167,875 sh | 167,875 | $4.2M | 0.67% | +16.1% |
| 82 | VIRGINIA RETIREMENT SYSTEMS ET Al#82 · 166,796 sh | 166,796 | $4.2M | 0.02% | +105.9% |
| 83 | GREAT LAKES ADVISORS#83 · 151,341 sh | 151,341 | $3.8M | 0.03% | -37.4% |
| 84 | BESSEMER GROUP#84 · 150,309 sh | 150,309 | $3.8M | <0.01% | -0.1% |
| 85 | AMERICAN CENTURY COMPANIES#85 · 143,688 sh | 143,688 | $3.6M | <0.01% | +81.3% |
| 86 | StemPoint Capital#86 · 143,167 sh | 143,167 | $3.6M | 0.62% | -41.0% |
| 87 | ALLIANCEBERNSTEIN L.P.#87 · 161,066 sh | 161,066 | $3.6M | <0.01% | +7.9% |
| 88 | Squarepoint Ops#88 · 140,013 sh | 140,013 | $3.5M | <0.01% | -62.2% |
| 89 | ROYAL BANK OF CANADA#89 · 139,664 sh | 139,664 | $3.5M | <0.01% | -37.4% |
| 90 | ORBIMED ADVISORS#90 · 137,000 sh | 137,000 | $3.5M | 0.06% | New |
| 91 | NATIXIS ADVISORS#91 · 135,958 sh | 135,958 | $3.4M | <0.01% | +35.4% |
| 92 | Erste Asset Management GmbH#92 · 133,700 sh | 133,700 | $3.4M | 0.03% | 0.0% |
| 93 | Emerald Investment Advisers#93 · 131,752 sh | 131,752 | $3.3M | 0.22% | +19.7% |
| 94 | VANGUARD ASSET MANAGEMENT, Ltd#94 · 123,724 sh | 123,724 | $3.1M | <0.01% | +8.4% |
| 95 | Longaeva Partners L.P.#95 · 117,318 sh | 117,318 | $3.0M | 0.06% | New |
| 96 | JACOBS LEVY EQUITY MANAGEMENT#96 · 116,553 sh | 116,553 | $2.9M | 0.01% | -18.3% |
| 97 | Trexquant Investment#97 · 116,022 sh | 116,022 | $2.9M | 0.02% | -50.8% |
| 98 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM#98 · 115,011 sh | 115,011 | $2.9M | <0.01% | -10.6% |
| 99 | JONES FINANCIAL COMPANIES LLLP#99 · 113,289 sh | 113,289 | $2.9M | <0.01% | +47.3% |
| 100 | JANE STREET GROUP#100 · 113,257 sh | 113,257 | $2.9M | <0.01% | -85.9% |
Funds that sold out of ACAD in Q2 2026 (36)
Held ACAD at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.