Twist Bioscience Corp (TWST) — Institutional Holders, Q2 2026
338 institutional investment managers reported a TWST position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $7.8B. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
TWST in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- PRICE T ROWE ASSOCIATESAdded · +3,564,347 sh+$366.7M
- FMRAdded · +2,813,099 sh+$289.4M
- D. E. ShawAdded · +1,138,961 sh+$117.2M
- Stephens Investment Management GroupNew · +767,364 sh+$78.9M
- FARALLON CAPITAL MANAGEMENTAdded · +708,750 sh+$72.9M
Biggest sellers
- WILLIAM BLAIR INVESTMENT MANAGEMENTTrimmed · -3,095,124 sh-$318.4M
- EdgePoint Investment GroupTrimmed · -2,860,886 sh-$294.3M
- ARK Investment ManagementTrimmed · -1,792,930 sh-$184.5M
- Artisan Partners Limited PartnershipTrimmed · -1,565,760 sh-$161.1M
- Soleus Capital Management, L.P.Trimmed · -1,122,000 sh-$115.4M
TWST 13F holders ranked 1–100 of 338
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | BlackRock#1 · 5,833,891 sh | 5,833,891 | $600.2M | <0.01% | +5.0% |
| 2 | Artisan Partners Limited Partnership#2 · 4,802,017 sh | 4,802,017 | $494.0M | 0.78% | -24.6% |
| 3 | FMR#3 · 4,703,044 sh | 4,703,044 | $483.8M | 0.02% | +148.8% |
| 4 | ARK Investment Management#4 · 4,549,803 sh | 4,549,803 | $468.1M | 3.04% | -28.3% |
| 5 | PRICE T ROWE ASSOCIATES#5 · 3,634,652 sh | 3,634,652 | $373.9M | 0.04% | +5069.8% |
| 6 | STATE STREET#6 · 3,232,532 sh | 3,232,532 | $332.6M | <0.01% | -11.9% |
| 7 | VANGUARD PORTFOLIO MANAGEMENT#7 · 2,824,989 sh | 2,824,989 | $290.6M | 0.01% | +6.6% |
| 8 | VANGUARD CAPITAL MANAGEMENT#8 · 2,699,280 sh | 2,699,280 | $277.7M | <0.01% | +2.3% |
| 9 | EdgePoint Investment Group#9 · 2,521,635 sh | 2,521,635 | $259.4M | 1.96% | -53.2% |
| 10 | WILLIAM BLAIR INVESTMENT MANAGEMENT#10 · 2,174,594 sh | 2,174,594 | $223.7M | 0.67% | -58.7% |
| 11 | FARALLON CAPITAL MANAGEMENT#11 · 2,136,400 sh | 2,136,400 | $219.8M | 1.01% | +49.6% |
| 12 | Invesco Ltd.#12 · 1,928,229 sh | 1,928,229 | $198.4M | 0.02% | -11.2% |
| 13 | GEODE CAPITAL MANAGEMENT#13 · 1,619,361 sh | 1,619,361 | $166.6M | <0.01% | +6.6% |
| 14 | THRIVENT FINANCIAL FOR LUTHERANS#14 · 1,433,503 sh | 1,433,503 | $147.5M | 0.25% | +9.2% |
| 15 | GOLDMAN SACHS GROUP#15 · 1,408,418 sh | 1,408,418 | $144.9M | 0.01% | -17.4% |
| 16 | MORGAN STANLEY#16 · 1,189,861 sh | 1,189,861 | $122.4M | <0.01% | +117.6% |
| 17 | D. E. Shaw#17 · 1,185,605 sh | 1,185,605 | $122.0M | 0.06% | +2441.8% |
| 18 | BAILLIE GIFFORD#18 · 1,086,779 sh | 1,086,779 | $111.8M | 0.10% | -10.6% |
| 19 | DRIEHAUS CAPITAL MANAGEMENT#19 · 1,022,526 sh | 1,022,526 | $105.2M | 0.61% | +74.9% |
| 20 | Sumitomo Mitsui#20 · 1,000,344 sh | 1,000,344 | $102.9M | 0.06% | -33.1% |
| 21 | Nikko Asset Management Americas#21 · 999,734 sh | 999,734 | $102.8M | 1.33% | -33.2% |
| 22 | BANK OF AMERICA#22 · 922,647 sh | 922,647 | $94.9M | <0.01% | +57.9% |
| 23 | CITADEL ADVISORS#23 · 862,042 sh | 862,042 | $88.7M | 0.01% | -29.4% |
| 24 | LOOMIS SAYLES & L P#24 · 861,309 sh | 861,309 | $88.6M | 0.11% | +75.0% |
| 25 | Stephens Investment Management Group#25 · 767,364 sh | 767,364 | $78.9M | 0.85% | New |
| 26 | First Light Asset Management#26 · 727,933 sh | 727,933 | $74.9M | 4.55% | -17.2% |
| 27 | VOYA INVESTMENT MANAGEMENT#27 · 671,866 sh | 671,866 | $69.1M | 0.06% | +6367.7% |
| 28 | FIL Ltd#28 · 641,096 sh | 641,096 | $66.0M | 0.05% | New |
| 29 | T. Rowe Price Investment Management#29 · 597,935 sh | 597,935 | $61.5M | 0.04% | New |
| 30 | NORTHERN#30 · 591,688 sh | 591,688 | $60.9M | <0.01% | +12.1% |
| 31 | DIMENSIONAL FUND ADVISORS#31 · 582,702 sh | 582,702 | $59.9M | 0.01% | -25.4% |
| 32 | WELLINGTON MANAGEMENT GROUP LLP#32 · 568,347 sh | 568,347 | $58.5M | 0.01% | -23.1% |
| 33 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AME#33 · 563,782 sh | 563,782 | $58.0M | 0.01% | -31.6% |
| 34 | FRED ALGER MANAGEMENT#34 · 558,157 sh | 558,157 | $57.4M | 0.19% | +482.7% |
| 35 | CHARLES SCHWAB INVESTMENT MANAGEMENT#35 · 557,131 sh | 557,131 | $57.3M | <0.01% | +3.7% |
| 36 | BNP PARIBAS FINANCIAL MARKETS#36 · 546,647 sh | 546,647 | $56.2M | 0.02% | -9.5% |
| 37 | Nuveen#37 · 522,043 sh | 522,043 | $53.7M | 0.01% | +77.8% |
| 38 | AMERICAN CENTURY COMPANIES#38 · 487,031 sh | 487,031 | $50.1M | 0.02% | +1187.1% |
| 39 | Tao Capital Management#39 · 478,815 sh | 478,815 | $49.3M | 2.54% | -42.2% |
| 40 | NEW YORK STATE COMMON RETIREMENT FUND#40 · 462,145 sh | 462,145 | $47.5M | 0.06% | -31.4% |
| 41 | JENNISON ASSOCIATES#41 · 453,216 sh | 453,216 | $46.6M | 0.03% | -25.1% |
| 42 | VANGUARD FIDUCIARY#42 · 443,474 sh | 443,474 | $45.6M | 0.01% | +4.8% |
| 43 | Allspring Global Investments#43 · 418,129 sh | 418,129 | $42.8M | 0.07% | -8.2% |
| 44 | UBS Group AG#44 · 413,127 sh | 413,127 | $42.5M | <0.01% | -8.7% |
| 45 | MARSHALL WACE, LLP#45 · 396,912 sh | 396,912 | $40.8M | 0.03% | New |
| 46 | MILLENNIUM MANAGEMENT#46 · 347,148 sh | 347,148 | $35.7M | 0.01% | -1.0% |
| 47 | AMERIPRISE FINANCIAL#47 · 340,072 sh | 340,072 | $35.0M | <0.01% | +921.2% |
| 48 | Granahan Investment Management#48 · 314,882 sh | 314,882 | $32.4M | 1.15% | New |
| 49 | LORD, ABBETT#49 · 299,256 sh | 299,256 | $30.8M | 0.09% | +200.4% |
| 50 | FEDERATED HERMES#50 · 298,113 sh | 298,113 | $30.7M | 0.04% | New |
| 51 | SEI INVESTMENTS#51 · 294,931 sh | 294,931 | $30.3M | 0.03% | -16.8% |
| 52 | BLAIR WILLIAM#52 · 256,556 sh | 256,556 | $26.4M | 0.07% | +346.8% |
| 53 | Trexquant Investment#53 · 255,271 sh | 255,271 | $26.3M | 0.15% | +50.1% |
| 54 | USS Investment Management Ltd#54 · 241,224 sh | 241,224 | $24.8M | 0.09% | New |
| 55 | JPMORGAN CHASE#55 · 205,248 sh | 205,248 | $20.5M | <0.01% | -0.3% |
| 56 | SILVERCREST ASSET MANAGEMENT GROUP#56 · 196,496 sh | 196,496 | $20.2M | 0.13% | -19.5% |
| 57 | IQ EQ FUND MANAGEMENT (IRELAND) Ltd#57 · 191,845 sh | 191,845 | $19.7M | 1.26% | -32.6% |
| 58 | Bank of New York Mellon#58 · 191,698 sh | 191,698 | $19.7M | <0.01% | +6.0% |
| 59 | FIRST ADVISORS#59 · 190,879 sh | 190,879 | $19.6M | 0.01% | +82.4% |
| 60 | Freshford Capital Management#60 · 177,449 sh | 177,449 | $18.3M | 6.25% | -31.5% |
| 61 | STATE TREASURER STATE OF MICHIGAN#61 · 177,401 sh | 177,401 | $18.3M | — | +15.8% |
| 62 | Metavasi Capital#62 · 176,004 sh | 176,004 | $18.1M | 6.32% | +76.0% |
| 63 | Universal- Beteiligungs- und Servicegesellschaft mbH#63 · 153,667 sh | 153,667 | $15.8M | 0.02% | +17.1% |
| 64 | Neuberger Berman Group#64 · 145,642 sh | 145,642 | $15.0M | 0.01% | +34.5% |
| 65 | ARMISTICE CAPITAL#65 · 142,000 sh | 142,000 | $14.6M | 0.18% | New |
| 66 | PEREGRINE CAPITAL MANAGEMENT#66 · 138,970 sh | 138,970 | $14.3M | 0.46% | -36.9% |
| 67 | AQR CAPITAL MANAGEMENT#67 · 129,391 sh | 129,391 | $13.3M | <0.01% | +3.7% |
| 68 | Science & Technology Partners, L.P.#68 · 129,228 sh | 129,228 | $13.3M | 2.24% | New |
| 69 | Legal & General Group Plc#69 · 121,980 sh | 121,980 | $12.5M | <0.01% | -4.8% |
| 70 | PARNASSUS INVESTMENTS#70 · 120,001 sh | 120,001 | $12.3M | — | New |
| 71 | Swiss National Bank#71 · 113,800 sh | 113,800 | $11.7M | <0.01% | -4.4% |
| 72 | OSTERWEIS CAPITAL MANAGEMENT#72 · 111,458 sh | 111,458 | $11.5M | 0.54% | -47.2% |
| 73 | Atika Capital Management#73 · 108,000 sh | 108,000 | $11.1M | 0.73% | New |
| 74 | Soleus Capital Management, L.P.#74 · 104,629 sh | 104,629 | $10.8M | 0.37% | -91.5% |
| 75 | TD ASSET MANAGEMENT#75 · 103,986 sh | 103,986 | $10.7M | <0.01% | +1530.9% |
| 76 | Pictet Asset Management Holding SA#76 · 108,267 sh | 108,267 | $10.7M | 0.01% | -41.8% |
| 77 | MIRAE ASSET GLOBAL ETFS Ltd.#77 · 100,108 sh | 100,108 | $10.3M | 0.01% | +26.6% |
| 78 | RHUMBLINE ADVISERS#78 · 99,388 sh | 99,388 | $10.2M | <0.01% | +10.4% |
| 79 | Mawer Investment Management Ltd.#79 · 99,251 sh | 99,251 | $10.2M | 0.07% | New |
| 80 | Russell Investments Group, Ltd.#80 · 97,616 sh | 97,616 | $10.0M | <0.01% | +46.6% |
| 81 | TWO SIGMA INVESTMENTS#81 · 94,600 sh | 94,600 | $9.7M | <0.01% | +154.3% |
| 82 | DEUTSCHE BANK AG\#82 · 90,053 sh | 90,053 | $9.3M | <0.01% | +39.5% |
| 83 | NOMURA ASSET MANAGEMENT INTERNATIONAL#83 · 89,273 sh | 89,273 | $9.2M | 0.01% | -41.5% |
| 84 | HRT FINANCIAL#84 · 88,043 sh | 88,043 | $9.1M | 0.02% | New |
| 85 | ODDO BHF ASSET MANAGEMENT SAS#85 · 88,006 sh | 88,006 | $9.1M | 0.42% | -39.7% |
| 86 | JANE STREET GROUP#86 · 86,284 sh | 86,284 | $8.9M | <0.01% | -85.6% |
| 87 | Vestmark Advisory Solutions#87 · 85,142 sh | 85,142 | $8.8M | 0.08% | -22.1% |
| 88 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#88 · 79,848 sh | 79,848 | $8.2M | <0.01% | +223.8% |
| 89 | CITIGROUP#89 · 77,626 sh | 77,626 | $8.0M | <0.01% | -83.1% |
| 90 | WELLS FARGO & COMPANY#90 · 77,336 sh | 77,336 | $8.0M | <0.01% | +151.0% |
| 91 | Ensign Peak Advisors#91 · 74,314 sh | 74,314 | $7.6M | 0.01% | -0.9% |
| 92 | ENVESTNET ASSET MANAGEMENT#92 · 66,627 sh | 66,627 | $6.9M | <0.01% | +1.6% |
| 93 | LPL Financial#93 · 63,897 sh | 63,897 | $6.6M | <0.01% | +12.3% |
| 94 | Informed Momentum#94 · 62,564 sh | 62,564 | $6.4M | 0.57% | New |
| 95 | PRINCIPAL FINANCIAL GROUP#95 · 58,508 sh | 58,508 | $6.0M | <0.01% | -45.2% |
| 96 | Man Group plc#96 · 58,295 sh | 58,295 | $6.0M | <0.01% | -39.6% |
| 97 | POLEN CAPITAL MANAGEMENT#97 · 55,310 sh | 55,310 | $5.7M | 0.05% | +130.1% |
| 98 | VANGUARD ASSET MANAGEMENT, Ltd#98 · 54,810 sh | 54,810 | $5.6M | <0.01% | +5.0% |
| 99 | Susquehanna Portfolio Strategies#99 · 54,617 sh | 54,617 | $5.6M | 0.09% | New |
| 100 | HARBOR CAPITAL ADVISORS#100 · 53,282 sh | 53,282 | $5.5M | — | +42.5% |
Funds that sold out of TWST in Q2 2026 (31)
Held TWST at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.