Seaport Therapeutics, Inc. (SPTX) — Institutional Holders, Q2 2026
55 institutional investment managers reported a SPTX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $815.3M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
SPTX 13F holders ranked 1–55 of 55
| # | Institution | Shares | Value | % of portfolio | QoQShares vs prior Q |
|---|---|---|---|---|---|
| 1 | ARCH Venture Management#1 · 6,294,951 sh | 6,294,951 | $136.6M | 12.42% | — |
| 2 | GENERAL ATLANTIC, L.P.#2 · 6,101,582 sh | 6,101,582 | $132.5M | 4.56% | — |
| 3 | Sofinnova Ventures#3 · 3,564,871 sh | 3,564,871 | $77.4M | 4.00% | — |
| 4 | GOLDMAN SACHS GROUP#4 · 2,178,642 sh | 2,178,642 | $47.3M | <0.01% | — |
| 5 | TRV GP VI#5 · 2,061,222 sh | 2,061,222 | $44.8M | 19.27% | — |
| 6 | CANADA PENSION PLAN INVESTMENT BOARD#6 · 1,975,791 sh | 1,975,791 | $42.9M | 0.02% | — |
| 7 | JPMORGAN CHASE#7 · 1,815,845 sh | 1,815,845 | $40.9M | <0.01% | — |
| 8 | Foresite Capital Management VI#8 · 1,779,521 sh | 1,779,521 | $38.7M | 6.01% | — |
| 9 | PRICE T ROWE ASSOCIATES#9 · 1,308,604 sh | 1,308,604 | $28.4M | <0.01% | — |
| 10 | FMR#10 · 1,185,100 sh | 1,185,100 | $25.7M | <0.01% | — |
| 11 | Bellevue Group AG#11 · 1,100,000 sh | 1,100,000 | $23.9M | 0.50% | — |
| 12 | Siren, L.L.C.#12 · 1,095,316 sh | 1,095,316 | $23.8M | 0.48% | — |
| 13 | JENNISON ASSOCIATES#13 · 1,079,669 sh | 1,079,669 | $23.5M | 0.01% | — |
| 14 | RA CAPITAL MANAGEMENT, L.P.#14 · 700,000 sh | 700,000 | $15.2M | 0.13% | — |
| 15 | VANGUARD CAPITAL MANAGEMENT#15 · 599,217 sh | 599,217 | $13.0M | <0.01% | — |
| 16 | Woodline Partners#16 · 586,345 sh | 586,345 | $12.7M | 0.04% | — |
| 17 | PERCEPTIVE ADVISORS#17 · 500,000 sh | 500,000 | $10.9M | 0.16% | — |
| 18 | BRAIDWELL#18 · 500,000 sh | 500,000 | $10.9M | 0.40% | — |
| 19 | PRINCIPAL FINANCIAL GROUP#19 · 414,672 sh | 414,672 | $9.0M | <0.01% | — |
| 20 | abrdn plc#20 · 310,355 sh | 310,355 | $6.7M | <0.01% | — |
| 21 | UBS Group AG#21 · 279,184 sh | 279,184 | $6.1M | <0.01% | — |
| 22 | BlackRock#22 · 229,863 sh | 229,863 | $5.0M | <0.01% | — |
| 23 | SEVEN GRAND MANAGERS#23 · 225,000 sh | 225,000 | $4.9M | 0.20% | — |
| 24 | CITADEL ADVISORS#24 · 191,144 sh | 191,144 | $4.2M | <0.01% | — |
| 25 | GEODE CAPITAL MANAGEMENT#25 · 175,866 sh | 175,866 | $3.8M | <0.01% | — |
| 26 | Pier Capital#26 · 169,985 sh | 169,985 | $3.7M | 0.49% | — |
| 27 | AMERIPRISE FINANCIAL#27 · 131,788 sh | 131,788 | $2.9M | <0.01% | — |
| 28 | CHARLES SCHWAB INVESTMENT MANAGEMENT#28 · 97,693 sh | 97,693 | $2.1M | <0.01% | — |
| 29 | VANGUARD FIDUCIARY#29 · 87,772 sh | 87,772 | $1.9M | <0.01% | — |
| 30 | Pentwater Capital Management#30 · 83,000 sh | 83,000 | $1.8M | 0.01% | — |
| 31 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#31 · 82,565 sh | 82,565 | $1.8M | <0.01% | — |
| 32 | Alyeska Investment Group, L.P.#32 · 75,000 sh | 75,000 | $1.6M | <0.01% | — |
| 33 | STATE STREET#33 · 66,650 sh | 66,650 | $1.4M | 0.00% | — |
| 34 | ALPS ADVISORS#34 · 54,328 sh | 54,328 | $1.2M | <0.01% | — |
| 35 | TD ASSET MANAGEMENT#35 · 47,944 sh | 47,944 | $1.0M | <0.01% | — |
| 36 | MILLENNIUM MANAGEMENT#36 · 45,337 sh | 45,337 | $984.7K | <0.01% | — |
| 37 | GSA CAPITAL PARTNERS LLP#37 · 33,178 sh | 33,178 | $721.0K | 0.05% | — |
| 38 | DAFNA Capital Management#38 · 32,400 sh | 32,400 | $703.7K | 0.13% | — |
| 39 | NORTHERN#39 · 31,802 sh | 31,802 | $690.7K | <0.01% | — |
| 40 | ADAR1 Capital Management#40 · 26,000 sh | 26,000 | $564.7K | 0.03% | — |
| 41 | Ghisallo Capital Management#41 · 25,000 sh | 25,000 | $543.0K | 0.01% | — |
| 42 | Burkehill Global Management#42 · 25,000 sh | 25,000 | $543.0K | 0.02% | — |
| 43 | Squarepoint Ops#43 · 24,753 sh | 24,753 | $537.6K | <0.01% | — |
| 44 | HighTower Advisors#44 · 16,666 sh | 16,666 | $362.0K | <0.01% | — |
| 45 | MORGAN STANLEY#45 · 11,692 sh | 11,692 | $254.0K | 0.00% | — |
| 46 | XTX Topco Ltd#46 · 10,983 sh | 10,983 | $238.6K | <0.01% | — |
| 47 | Weiss Asset Management#47 · 10,000 sh | 10,000 | $217.2K | <0.01% | — |
| 48 | Zimmer Partners#48 · 10,000 sh | 10,000 | $217.2K | <0.01% | — |
| 49 | VANGUARD PORTFOLIO MANAGEMENT#49 · 9,081 sh | 9,081 | $197.2K | 0.00% | — |
| 50 | Vanguard Global Advisers#50 · 7,159 sh | 7,159 | $155.5K | <0.01% | — |
| 51 | CITIGROUP#51 · 2,454 sh | 2,454 | $53.3K | 0.00% | — |
| 52 | JONES FINANCIAL COMPANIES LLLP#52 · 2,256 sh | 2,256 | $48.3K | 0.00% | — |
| 53 | ASSETMARK#53 · 1,431 sh | 1,431 | $31.1K | — | — |
| 54 | BARCLAYS PLC#54 · 837 sh | 837 | $18.2K | 0.00% | — |
| 55 | Integrated Wealth Concepts#55 · 32 sh | 32 | $695.00 | 0.00% | — |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for the prior quarter without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.