Q32 Bio Inc. (QTTB) — Institutional Holders, Q2 2026
71 institutional investment managers reported a QTTB position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $282.6M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
QTTB in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- Boxer Capital ManagementNew · +3,149,310 sh+$40.1M
- BVFNew · +2,350,000 sh+$29.9M
- RA CAPITAL MANAGEMENT, L.P.New · +2,332,457 sh+$29.7M
- ORBIMED ADVISORSAdded · +1,875,000 sh+$23.9M
- Point72 Asset Management, L.P.New · +1,173,396 sh+$14.9M
Biggest sellers
- Carlyle GroupTrimmed · -1,042,378 sh-$13.3M
- Opaleye ManagementTrimmed · -325,228 sh-$4.1M
- ARCH Venture ManagementSold out · -320,482 sh-$4.1M
- MACKENZIE FINANCIALSold out · -246,304 sh-$3.1M
- PFIZERSold out · -101,618 sh-$1.3M
QTTB 13F holders ranked 1–71 of 71
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS#1 · 4,127,987 sh | 4,127,987 | $52.6M | 0.97% | +83.2% |
| 2 | Boxer Capital Management#2 · 3,149,310 sh | 3,149,310 | $40.1M | 3.02% | New |
| 3 | Atlas Venture Life Science Advisors#3 · 2,717,106 sh | 2,717,106 | $34.6M | 3.93% | +29.9% |
| 4 | BVF#4 · 2,350,000 sh | 2,350,000 | $29.9M | 0.77% | New |
| 5 | RA CAPITAL MANAGEMENT, L.P.#5 · 2,332,457 sh | 2,332,457 | $29.7M | 0.26% | New |
| 6 | Point72 Asset Management, L.P.#6 · 1,173,396 sh | 1,173,396 | $14.9M | 0.02% | New |
| 7 | Opaleye Management#7 · 931,000 sh | 931,000 | $11.9M | 1.07% | -25.9% |
| 8 | Logos Global Management#8 · 800,000 sh | 800,000 | $10.2M | 0.44% | New |
| 9 | SummitTX Capital, L.P.#9 · 733,774 sh | 733,774 | $9.3M | 0.24% | New |
| 10 | VANGUARD CAPITAL MANAGEMENT#10 · 518,803 sh | 518,803 | $6.6M | <0.01% | +69.3% |
| 11 | Ikarian Capital#11 · 430,000 sh | 430,000 | $5.5M | 0.59% | New |
| 12 | Woodline Partners#12 · 286,212 sh | 286,212 | $3.6M | 0.01% | New |
| 13 | AMERICAN CENTURY COMPANIES#13 · 272,752 sh | 272,752 | $3.5M | <0.01% | +1353.1% |
| 14 | Sanofi#14 · 244,083 sh | 244,083 | $3.1M | 0.58% | 0.0% |
| 15 | ACADIAN ASSET MANAGEMENT#15 · 218,234 sh | 218,234 | $2.8M | <0.01% | +26.4% |
| 16 | ACORN CAPITAL ADVISORS#16 · 216,171 sh | 216,171 | $2.8M | 0.75% | -31.4% |
| 17 | RENAISSANCE TECHNOLOGIES#17 · 179,600 sh | 179,600 | $2.3M | <0.01% | -13.2% |
| 18 | JANE STREET GROUP#18 · 162,747 sh | 162,747 | $2.1M | <0.01% | +148.1% |
| 19 | MONIMUS CAPITAL MANAGEMENT#19 · 132,036 sh | 132,036 | $1.7M | 0.39% | -1.7% |
| 20 | BOOTHBAY FUND MANAGEMENT#20 · 130,427 sh | 130,427 | $1.7M | 0.02% | New |
| 21 | GEODE CAPITAL MANAGEMENT#21 · 122,690 sh | 122,690 | $1.6M | <0.01% | +3.8% |
| 22 | CITADEL ADVISORS#22 · 120,663 sh | 120,663 | $1.5M | <0.01% | +679.4% |
| 23 | BlackRock#23 · 118,507 sh | 118,507 | $1.5M | 0.00% | +37.6% |
| 24 | MARSHALL WACE, LLP#24 · 67,045 sh | 67,045 | $854.2K | <0.01% | +27.9% |
| 25 | VANGUARD FIDUCIARY#25 · 66,217 sh | 66,217 | $843.6K | <0.01% | +32.4% |
| 26 | Carlyle Group#26 · 60,363 sh | 60,363 | $769.0K | <0.01% | -94.5% |
| 27 | STATE STREET#27 · 52,214 sh | 52,214 | $665.2K | 0.00% | +25.8% |
| 28 | TWO SIGMA INVESTMENTS#28 · 49,582 sh | 49,582 | $631.7K | <0.01% | +17.1% |
| 29 | Quadrature Capital Ltd#29 · 36,396 sh | 36,396 | $463.7K | <0.01% | New |
| 30 | BRIDGEWAY CAPITAL MANAGEMENT#30 · 34,613 sh | 34,613 | $441.0K | <0.01% | +174.4% |
| 31 | DAFNA Capital Management#31 · 32,896 sh | 32,896 | $419.1K | 0.08% | New |
| 32 | Knott David M Jr#32 · 30,412 sh | 30,412 | $387.4K | 0.20% | New |
| 33 | Affinity Asset Advisors#33 · 27,777 sh | 27,777 | $353.9K | 0.02% | 0.0% |
| 34 | Squarepoint Ops#34 · 23,790 sh | 23,790 | $303.1K | <0.01% | New |
| 35 | NORTHERN#35 · 23,631 sh | 23,631 | $301.1K | 0.00% | -5.6% |
| 36 | DIMENSIONAL FUND ADVISORS#36 · 23,588 sh | 23,588 | $300.5K | <0.01% | New |
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#37 · 23,342 sh | 23,342 | $297.4K | 0.00% | New |
| 38 | MANGROVE PARTNERS IM#38 · 22,150 sh | 22,150 | $282.2K | 0.02% | New |
| 39 | LPL Financial#39 · 18,170 sh | 18,170 | $231.5K | <0.01% | New |
| 40 | Cambridge Investment Research Advisors#40 · 18,081 sh | 18,081 | $230.0K | <0.01% | -48.4% |
| 41 | HRT FINANCIAL#41 · 15,949 sh | 15,949 | $203.0K | <0.01% | New |
| 42 | UBS Group AG#42 · 15,008 sh | 15,008 | $191.2K | 0.00% | +5458.5% |
| 43 | BALYASNY ASSET MANAGEMENT L.P.#43 · 12,342 sh | 12,342 | $157.2K | <0.01% | New |
| 44 | ExodusPoint Capital Management#44 · 11,336 sh | 11,336 | $144.4K | <0.01% | New |
| 45 | MILLENNIUM MANAGEMENT#45 · 10,928 sh | 10,928 | $139.2K | <0.01% | New |
| 46 | XTX Topco Ltd#46 · 10,874 sh | 10,874 | $138.5K | <0.01% | New |
| 47 | MORGAN STANLEY#47 · 6,456 sh | 6,456 | $82.3K | 0.00% | -32.5% |
| 48 | Vanguard Global Advisers#48 · 4,824 sh | 4,824 | $61.5K | 0.00% | +151.9% |
| 49 | FMR#49 · 3,388 sh | 3,388 | $43.2K | 0.00% | -0.4% |
| 50 | CITIGROUP#50 · 2,888 sh | 2,888 | $36.8K | 0.00% | New |
| 51 | Private Wealth Asset Management#51 · 1,700 sh | 1,700 | $21.7K | <0.01% | New |
| 52 | SRS Capital Advisors#52 · 1,111 sh | 1,111 | $14.2K | <0.01% | -3.2% |
| 53 | FEDERATED HERMES#53 · 1,050 sh | 1,050 | $13.4K | 0.00% | -53.8% |
| 54 | Rockefeller Capital Management L.P.#54 · 577 sh | 577 | $7.4K | 0.00% | 0.0% |
| 55 | JONES FINANCIAL COMPANIES LLLP#55 · 500 sh | 500 | $6.6K | 0.00% | 0.0% |
| 56 | Russell Investments Group, Ltd.#56 · 454 sh | 454 | $5.8K | 0.00% | 0.0% |
| 57 | BNP PARIBAS FINANCIAL MARKETS#57 · 303 sh | 303 | $3.9K | 0.00% | 0.0% |
| 58 | EverSource Wealth Advisors#58 · 240 sh | 240 | $3.1K | <0.01% | -78.4% |
| 59 | NISA INVESTMENT ADVISORS#59 · 166 sh | 166 | $2.1K | — | 0.0% |
| 60 | Truvestments Capital#60 · 162 sh | 162 | $2.1K | <0.01% | New |
| 61 | OSAIC#61 · 124 sh | 124 | $1.6K | 0.00% | 0.0% |
| 62 | Allworth Financial#62 · 108 sh | 108 | $1.4K | 0.00% | +10.2% |
| 63 | SBI Securities , Ltd.#63 · 94 sh | 94 | $1.2K | — | -9.6% |
| 64 | Federation des caisses Desjardins du Quebec#64 · 70 sh | 70 | $888.00 | 0.00% | 0.0% |
| 65 | Clearstead Advisors#65 · 67 sh | 67 | $854.00 | 0.00% | New |
| 66 | Caitong International Asset Management , Ltd#66 · 45 sh | 45 | $573.00 | <0.01% | New |
| 67 | GROUP ONE TRADING, L.P.#67 · 34 sh | 34 | $433.00 | 0.00% | 0.0% |
| 68 | HARBOUR INVESTMENTS#68 · 11 sh | 11 | $140.00 | 0.00% | 0.0% |
| 69 | AdvisorNet Financial#69 · 2 sh | 2 | $25.00 | — | 0.0% |
| 70 | DANSKE BANK A/S#70 · 1 sh | 1 | $13.00 | 0.00% | 0.0% |
| 71 | ROYAL BANK OF CANADA#71 · 43 sh | 43 | $0.00 | 0.00% | -98.4% |
Funds that sold out of QTTB in Q2 2026 (8)
Held QTTB at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| ARCH Venture Management320,482 sh | 320,482 | $2.1M |
| MACKENZIE FINANCIAL246,304 sh | 246,304 | $1.6M |
| PFIZER101,618 sh | 101,618 | $736.7K |
| ADAR1 Capital Management35,000 sh | 35,000 | $224.7K |
| Cetera Investment Advisers20,695 sh | 20,695 | $132.9K |
| Tower Research Capital (TRC)1,871 sh | 1,871 | $12.0K |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT111 sh | 111 | $713.00 |
| WELLS FARGO & COMPANY84 sh | 84 | $539.00 |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.