Polaryx Therapeutics, Inc. (PLYX) — Institutional Holders, Q2 2026

13 institutional investment managers reported a PLYX position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $5.8M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

PLYX in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

4

Added to

3

Trimmed

2

Sold out

5

Biggest buyers

  1. HRT FINANCIALNew · +82,094 sh+$218.4K
  2. JANE STREET GROUPNew · +31,441 sh+$83.6K
  3. Allworth FinancialNew · +7,727 sh+$20.6K
  4. Tower Research Capital (TRC)Added · +1,221 sh+$3.2K
  5. VANGUARD FIDUCIARYAdded · +516 sh+$1.4K

Biggest sellers

  1. MILLENNIUM MANAGEMENTSold out · -127,525 sh-$339.2K
  2. BANK OF AMERICASold out · -25,881 sh-$68.8K
  3. GOLDMAN SACHS GROUPSold out · -13,483 sh-$35.9K
  4. Squarepoint OpsSold out · -12,406 sh-$33.0K
  5. UBS Group AGTrimmed · -12,196 sh-$32.4K

PLYX 13F holders ranked 1–13 of 13

Institutional investors reporting a position in Polaryx Therapeutics, Inc. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
InstitutionValueQoQ
VANGUARD CAPITAL MANAGEMENT#1 · 1,657,872 sh$4.4M0.0%
GEODE CAPITAL MANAGEMENT#2 · 170,998 sh$455.1K+0.2%
VANGUARD FIDUCIARY#3 · 105,072 sh$279.5K+0.5%
HRT FINANCIAL#4 · 82,094 sh$218.0KNew
STATE STREET#5 · 58,104 sh$154.6K0.0%
BlackRock#6 · 41,012 sh$109.1K0.0%
JANE STREET GROUP#7 · 31,441 sh$83.6KNew
NORTHERN#8 · 27,987 sh$74.4K0.0%
Allworth Financial#9 · 7,727 sh$20.6KNew
Vanguard Global Advisers#10 · 6,318 sh$16.8K0.0%
Tower Research Capital (TRC)#11 · 3,002 sh$8.0K+68.6%
UBS Group AG#12 · 1,283 sh$3.4K-90.5%
Fortitude Family Office#13 · 189 sh$503.00New

Funds that sold out of PLYX in Q2 2026 (5)

Held PLYX at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held PLYX in Q1 2026 and reported no position in Q2 2026.
InstitutionValue in Q1 2026
MILLENNIUM MANAGEMENT127,525 sh$964.1K
BANK OF AMERICA25,881 sh$195.7K
GOLDMAN SACHS GROUP13,483 sh$101.9K
Squarepoint Ops12,406 sh$93.8K
MORGAN STANLEY5,543 sh$41.9K

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.