HYPERION DEFI, INC. (HYPD) — Institutional Holders, Q2 2026

33 institutional investment managers reported a HYPD position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $7.9M. Every filer is listed below, ranked by position value. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

HYPD in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

14

Added to

6

Trimmed

6

Sold out

5

Biggest buyers

  1. VANGUARD CAPITAL MANAGEMENTNew · +466,798 sh+$1.5M
  2. FRANKLIN RESOURCESNew · +395,939 sh+$1.2M
  3. Arrington Capital ManagementNew · +297,777 sh+$935.0K
  4. Almanack Investment PartnersNew · +169,013 sh+$530.7K
  5. GOLDMAN SACHS GROUPNew · +91,390 sh+$287.0K

Biggest sellers

  1. RENAISSANCE TECHNOLOGIESSold out · -115,641 sh-$363.1K
  2. CITADEL ADVISORSTrimmed · -56,607 sh-$177.7K
  3. INVESTMENT HOUSETrimmed · -34,575 sh-$108.6K
  4. UBS Group AGTrimmed · -15,611 sh-$49.0K
  5. XTX Topco LtdTrimmed · -13,286 sh-$41.7K

HYPD 13F holders ranked 1–33 of 33

Institutional investors reporting a position in HYPERION DEFI, INC. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
InstitutionValueQoQ
VANGUARD CAPITAL MANAGEMENT#1 · 466,798 sh$1.5MNew
FRANKLIN RESOURCES#2 · 395,939 sh$1.2MNew
Arrington Capital Management#3 · 297,777 sh$935.0KNew
MORGAN STANLEY#4 · 237,986 sh$747.3K0.0%
Almanack Investment Partners#5 · 169,013 sh$530.7KNew
GEODE CAPITAL MANAGEMENT#6 · 130,707 sh$410.5K+69.6%
JANE STREET GROUP#7 · 127,491 sh$400.3K-0.6%
OPPENHEIMER#8 · 126,365 sh$396.8K+96.6%
BlackRock#9 · 114,400 sh$359.2K+41.0%
GOLDMAN SACHS GROUP#10 · 91,390 sh$287.0KNew
VANGUARD FIDUCIARY#11 · 74,455 sh$233.8KNew
CITADEL ADVISORS#12 · 56,299 sh$176.8K-50.1%
STATE STREET#13 · 54,357 sh$170.7K+110.2%
UBS Group AG#14 · 33,179 sh$104.2K-32.0%
NORTHERN#15 · 30,896 sh$97.0K+64.9%
PRICE T ROWE ASSOCIATES#16 · 20,500 sh$65.0K0.0%
PEAK6#17 · 20,000 sh$62.8KNew
INVESTMENT HOUSE#18 · 17,300 sh$54.3K-66.7%
JPMORGAN CHASE#19 · 16,107 sh$51.2KNew
XTX Topco Ltd#20 · 12,289 sh$38.6K-51.9%
NATIONS FINANCIAL GROUP , /IA#21 · 11,125 sh$34.9K0.0%
Sanctuary Advisors#22 · 10,800 sh$33.9K0.0%
BARCLAYS PLC#23 · 1,807 sh$5.7KNew
JONES FINANCIAL COMPANIES LLLP#24 · 1,768 sh$5.4KNew
WELLS FARGO & COMPANY#25 · 1,230 sh$3.9K+4000.0%
SBI Securities , Ltd.#26 · 1,219 sh$3.8K-36.3%
Tower Research Capital (TRC)#27 · 852 sh$2.7KNew
Vanguard Global Advisers#28 · 99 sh$311.00New
10Elms LLP#29 · 90 sh$283.000.0%
BNP PARIBAS FINANCIAL MARKETS#30 · 54 sh$170.000.0%
Caitong International Asset Management , Ltd#31 · 4 sh$13.00New
CITIGROUP#32 · 1 sh$3.00New
GROUP ONE TRADING, L.P.#33 · 1 sh$3.000.0%

Funds that sold out of HYPD in Q2 2026 (5)

Held HYPD at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held HYPD in Q1 2026 and reported no position in Q2 2026.
InstitutionValue in Q1 2026
RENAISSANCE TECHNOLOGIES115,641 sh$399.0K
STIFEL FINANCIAL10,395 sh$35.9K
ABOUND FINANCIAL890 sh$3.1K
Farther Finance Advisors105 sh$343.00
ROYAL BANK OF CANADA6 sh$0.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.