Cabaletta Bio, Inc. (CABA) — Institutional Holders, Q2 2026

141 institutional investment managers reported a CABA position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $490.4M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.

CABA in Q2 2026: what funds did

Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.

New positions

54

Added to

50

Trimmed

20

Sold out

23

Biggest buyers

  1. JENNISON ASSOCIATESAdded · +11,063,152 sh+$34.4M
  2. BlackRockAdded · +8,381,698 sh+$26.1M
  3. T. Rowe Price Investment ManagementAdded · +7,789,902 sh+$24.2M
  4. Bain Capital Life Sciences InvestorsAdded · +7,564,320 sh+$23.5M
  5. STATE STREETAdded · +7,369,327 sh+$22.9M

Biggest sellers

  1. MILLENNIUM MANAGEMENTTrimmed · -3,834,790 sh-$11.9M
  2. TWO SIGMA INVESTMENTSTrimmed · -1,086,986 sh-$3.4M
  3. MARSHALL WACE, LLPTrimmed · -613,879 sh-$1.9M
  4. Qube Research & Technologies LtdTrimmed · -508,150 sh-$1.6M
  5. RENAISSANCE TECHNOLOGIESTrimmed · -501,363 sh-$1.6M

CABA 13F holders ranked 1–100 of 141

Institutional investors reporting a position in Cabaletta Bio, Inc. on SEC Form 13F-HR for Q2 2026, ranked by reported value.
InstitutionValueQoQ
JENNISON ASSOCIATES#1 · 20,033,730 sh$62.3M+123.3%
T. Rowe Price Investment Management#2 · 18,869,907 sh$58.7M+70.3%
Bain Capital Life Sciences Investors#3 · 17,241,445 sh$53.6M+78.2%
BlackRock#4 · 10,754,701 sh$33.4M+353.2%
ADAGE CAPITAL PARTNERS GP, L.L.C.#5 · 9,174,758 sh$28.5M+3.9%
STATE STREET#6 · 7,839,305 sh$24.4M+1568.0%
VANGUARD CAPITAL MANAGEMENT#7 · 7,227,018 sh$22.5M+79.4%
Cormorant Asset Management#8 · 5,000,000 sh$15.6M-9.1%
PRICE T ROWE ASSOCIATES#9 · 4,418,674 sh$13.7M+899.1%
Woodline Partners#10 · 4,200,142 sh$13.1M+235.9%
NORGES BANK#11 · 4,112,401 sh$12.8M—
Opaleye Management#12 · 3,863,800 sh$12.0M+180.0%
CITADEL ADVISORS#13 · 3,522,112 sh$11.0MNew
GEODE CAPITAL MANAGEMENT#14 · 3,459,464 sh$10.8M+205.3%
FRANKLIN RESOURCES#15 · 2,413,937 sh$7.5MNew
GOLDMAN SACHS GROUP#16 · 2,211,825 sh$6.9M+182.4%
MILLENNIUM MANAGEMENT#17 · 2,068,491 sh$6.4M-65.0%
MARSHALL WACE, LLP#18 · 1,565,939 sh$4.9M-28.2%
RENAISSANCE TECHNOLOGIES#19 · 1,535,300 sh$4.8M-24.6%
UBS Group AG#20 · 1,471,895 sh$4.6M+142.6%
Qube Research & Technologies Ltd#21 · 1,426,840 sh$4.4M-26.3%
VANGUARD PORTFOLIO MANAGEMENT#22 · 1,418,108 sh$4.4MNew
TWO SIGMA INVESTMENTS#23 · 1,410,931 sh$4.4M-43.5%
MORGAN STANLEY#24 · 1,345,526 sh$4.2M-4.4%
SPHERA FUNDS MANAGEMENT LTD.#25 · 1,329,012 sh$4.1MNew
SUPERSTRING CAPITAL MANAGEMENT#26 · 1,278,652 sh$3.5M+19.9%
VANGUARD FIDUCIARY#27 · 1,088,595 sh$3.4M+90.9%
NORTHERN#28 · 1,007,102 sh$3.1M+322.4%
DIMENSIONAL FUND ADVISORS#29 · 967,195 sh$3.0M+30.6%
Stonepine Capital Management#30 · 917,100 sh$2.9M+1734.2%
SCHRODER INVESTMENT MANAGEMENT GROUP#31 · 856,637 sh$2.7M+13.2%
AMERIPRISE FINANCIAL#32 · 828,145 sh$2.6MNew
CANTOR FITZGERALD, L. P.#33 · 800,001 sh$2.5M+4.6%
HEIGHTS CAPITAL MANAGEMENT#34 · 755,626 sh$2.3MNew
Blue Owl Capital#35 · 714,710 sh$2.2MNew
Ikarian Capital#36 · 700,000 sh$2.2M-22.2%
Burkehill Global Management#37 · 700,000 sh$2.2M0.0%
GSA CAPITAL PARTNERS LLP#38 · 668,563 sh$2.1M+19.0%
Nuveen#39 · 646,345 sh$2.0MNew
KVP Capital Advisors#40 · 505,431 sh$1.6M0.0%
BANK OF AMERICA#41 · 493,314 sh$1.5M+83.2%
Jump Financial#42 · 488,775 sh$1.5M+2826.8%
Raiffeisen Bank International AG#43 · 430,000 sh$1.3M-4.4%
TD ASSET MANAGEMENT#44 · 391,472 sh$1.2M+485.0%
Susquehanna Portfolio Strategies#45 · 383,294 sh$1.2M+2078.4%
CHARLES SCHWAB INVESTMENT MANAGEMENT#46 · 374,886 sh$1.2M+637.6%
Bank of New York Mellon#47 · 304,819 sh$948.0K+461.4%
WELLINGTON MANAGEMENT GROUP LLP#48 · 286,212 sh$890.1K+15.6%
BRIDGEWAY CAPITAL MANAGEMENT#49 · 267,372 sh$831.5K0.0%
Invesco Ltd.#50 · 241,565 sh$751.3K+25.6%
WELLS FARGO & COMPANY#51 · 196,872 sh$612.3K+3181.2%
CITIGROUP#52 · 184,232 sh$573.0K+570.6%
BOOTHBAY FUND MANAGEMENT#53 · 182,455 sh$567.4K-25.1%
MANUFACTURERS LIFE INSURANCE COMPANY, THE#54 · 182,055 sh$566.2KNew
PANAGORA ASSET MANAGEMENT#55 · 161,916 sh$503.6KNew
SUSQUEHANNA FUNDAMENTAL INVESTMENTS#56 · 152,964 sh$475.7KNew
Rafferty Asset Management#57 · 146,107 sh$454.4KNew
Diametric Capital#58 · 135,598 sh$421.7K-48.4%
RHUMBLINE ADVISERS#59 · 131,640 sh$409.4KNew
Almitas Capital#60 · 125,900 sh$391.5K-62.7%
DEUTSCHE BANK AG\#61 · 110,962 sh$345.1KNew
Virtus Investment Advisers#62 · 108,703 sh$338.1KNew
ALLIANCEBERNSTEIN L.P.#63 · 108,410 sh$291.6KNew
D. E. Shaw#64 · 90,652 sh$281.9K-52.1%
LETKO, BROSSEAU & ASSOCIATES#65 · 90,475 sh$281.4K0.0%
Graham Capital Management, L.P.#66 · 81,279 sh$252.8K-20.1%
LPL Financial#67 · 79,075 sh$245.9K+13.7%
PROFUND ADVISORS#68 · 73,409 sh$228.3KNew
Virtu Financial#69 · 69,511 sh$216.0K+79.6%
MIRAE ASSET GLOBAL ETFS Ltd.#70 · 68,592 sh$213.3KNew
MetLife Investment Management#71 · 66,749 sh$207.6KNew
SUSQUEHANNA INTERNATIONAL GROUP, LLP#72 · 63,228 sh$196.6KNew
RAYMOND JAMES FINANCIAL#73 · 60,289 sh$187.5K+205.0%
JPMORGAN CHASE#74 · 59,368 sh$184.6K+723.9%
Vanguard Global Advisers#75 · 57,372 sh$178.4K+60.5%
MATAURO#76 · 55,108 sh$171.4K0.0%
Universal- Beteiligungs- und Servicegesellschaft mbH#77 · 54,086 sh$168.2KNew
EntryPoint Capital#78 · 50,927 sh$158.4KNew
ADAR1 Capital Management#79 · 50,000 sh$155.5KNew
XTX Topco Ltd#80 · 45,702 sh$142.1K+265.3%
BARCLAYS PLC#81 · 44,701 sh$139.0K-54.3%
KEYBANK NATIONAL ASSOCIATION#82 · 39,005 sh$121.3KNew
Quantbot Technologies#83 · 37,208 sh$115.7KNew
LOS ANGELES CAPITAL MANAGEMENT#84 · 34,419 sh$107.0KNew
Police & Firemen's Retirement System of New Jersey#85 · 33,203 sh$103.3KNew
Grey Ledge Advisors#86 · 30,000 sh$93.3K+50.0%
WINTON GROUP Ltd#87 · 27,000 sh$84.0K+76.5%
TWO SIGMA SECURITIES#88 · 26,663 sh$82.9KNew
China Universal Asset Management , Ltd.#89 · 25,950 sh$80.7K+51.9%
RITHOLTZ WEALTH MANAGEMENT#90 · 25,000 sh$77.8KNew
Wealthfront Advisers#91 · 24,389 sh$75.8KNew
NEW YORK STATE COMMON RETIREMENT FUND#92 · 23,400 sh$72.8KNew
INTECH INVESTMENT MANAGEMENT#93 · 23,035 sh$71.6KNew
VOYA INVESTMENT MANAGEMENT#94 · 21,377 sh$66.5KNew
E Fund Management , Ltd.#95 · 20,601 sh$64.1KNew
nVerses Capital#96 · 20,286 sh$63.1KNew
ProShare Advisors#97 · 20,086 sh$62.5KNew
BNP PARIBAS FINANCIAL MARKETS#98 · 19,609 sh$61.0K+1149.8%
Clear Harbor Asset Management#99 · 19,500 sh$60.6K0.0%
Callan Family Office#100 · 17,434 sh$54.2K0.0%

Funds that sold out of CABA in Q2 2026 (23)

Held CABA at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.

Institutions that held CABA in Q1 2026 and reported no position in Q2 2026.
InstitutionValue in Q1 2026
JANE STREET GROUP248,594 sh$668.7K
Point72 Asset Management, L.P.246,615 sh$663.4K
683 Capital Management225,000 sh$605.3K
Hudson Bay Capital Management161,726 sh$435.0K
Brevan Howard Capital Management149,721 sh$402.7K
Squarepoint Ops144,681 sh$389.2K
ExodusPoint Capital Management105,985 sh$285.1K
NOMURA95,512 sh$256.9K
Quadrature Capital Ltd87,060 sh$234.2K
OMERS ADMINISTRATION54,100 sh$145.5K
LEUCADIA NATIONAL33,442 sh$90.0K
HRT FINANCIAL33,104 sh$89.0K
AXQ CAPITAL28,938 sh$77.8K
Schonfeld Strategic Advisors28,172 sh$75.8K
MERCER GLOBAL ADVISORS26,510 sh$71.3K
QUADRANT CAPITAL GROUP12,990 sh$66.4K
Catalyst Funds Management Pty Ltd21,300 sh$57.3K
Private Advisor Group18,025 sh$48.5K
SummitTX Capital, L.P.12,522 sh$33.7K
BALYASNY ASSET MANAGEMENT L.P.11,154 sh$30.0K
Dynamic Technology Lab Private Ltd10,777 sh$29.0K
ANTIPODES PARTNERS Ltd5,616 sh$15.1K
Fortitude Family Office163 sh$438.00

Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.