ACHIEVE LIFE SCIENCES, INC. (ACHV) — Institutional Holders, Q2 2026
111 institutional investment managers reported a ACHV position on SEC Form 13F-HR for the quarter ended June 30, 2026, with a combined reported value of $538.7M. Every filer is listed below, ranked by position value, 100 per page; this page shows ranks 1 to 100. Put and call option positions are excluded, and a firm filing several lots or share classes is shown once with its total.
ACHV in Q2 2026: what funds did
Funds that filed a 13F for both Q1 2026 and Q2 2026, by what they did with the common stock. Share counts are adjusted for any split between the two quarters; dollar figures are the change in shares at this quarter’s price.
Biggest buyers
- Frazier Life Sciences Management, L.P.New · +7,614,836 sh+$49.7M
- TPG GP ANew · +6,877,580 sh+$44.9M
- venBio PartnersNew · +5,914,720 sh+$38.6M
- Logos Global ManagementNew · +5,425,000 sh+$35.4M
- Paradigm Biocapital AdvisorsNew · +4,951,856 sh+$32.3M
Biggest sellers
- FRANKLIN RESOURCESTrimmed · -3,785,166 sh-$24.7M
- Propel Bio ManagementTrimmed · -3,538,832 sh-$23.1M
- MILLENNIUM MANAGEMENTSold out · -2,154,676 sh-$14.1M
- Nantahala Capital ManagementSold out · -1,297,770 sh-$8.5M
- Simplify Asset ManagementTrimmed · -936,919 sh-$6.1M
ACHV 13F holders ranked 1–100 of 111
| # | Institution | Shares | Value | % of portfolio | QoQShares vs Q1 2026 |
|---|---|---|---|---|---|
| 1 | Frazier Life Sciences Management, L.P.#1 · 7,614,836 sh | 7,614,836 | $49.7M | 1.08% | New |
| 2 | TPG GP A#2 · 6,877,580 sh | 6,877,580 | $44.9M | 0.90% | New |
| 3 | venBio Partners#3 · 5,914,720 sh | 5,914,720 | $38.6M | 7.44% | New |
| 4 | Logos Global Management#4 · 5,425,000 sh | 5,425,000 | $35.4M | 1.52% | New |
| 5 | BlackRock#5 · 5,272,017 sh | 5,272,017 | $34.4M | <0.01% | +1099.9% |
| 6 | FRANKLIN RESOURCES#6 · 4,953,220 sh | 4,953,220 | $32.3M | <0.01% | +13.4% |
| 7 | Paradigm Biocapital Advisors#7 · 4,951,856 sh | 4,951,856 | $32.3M | 0.61% | New |
| 8 | VANGUARD CAPITAL MANAGEMENT#8 · 4,140,812 sh | 4,140,812 | $27.0M | <0.01% | +87.8% |
| 9 | Propel Bio Management#9 · 4,034,018 sh | 4,034,018 | $26.3M | 13.79% | +6.5% |
| 10 | MARSHALL WACE, LLP#10 · 3,770,313 sh | 3,770,313 | $24.6M | 0.02% | +269.9% |
| 11 | STATE STREET#11 · 2,945,526 sh | 2,945,526 | $19.2M | <0.01% | +1057.6% |
| 12 | VR Adviser#12 · 2,751,032 sh | 2,751,032 | $18.0M | 0.54% | New |
| 13 | Vivo Capital#13 · 2,751,032 sh | 2,751,032 | $18.0M | 1.64% | New |
| 14 | Jupiter Topco#14 · 2,751,032 sh | 2,751,032 | $18.0M | <0.01% | — |
| 15 | EVENTIDE ASSET MANAGEMENT#15 · 2,220,000 sh | 2,220,000 | $14.5M | 0.19% | New |
| 16 | GEODE CAPITAL MANAGEMENT#16 · 2,062,721 sh | 2,062,721 | $13.5M | <0.01% | +231.2% |
| 17 | Alyeska Investment Group, L.P.#17 · 1,925,722 sh | 1,925,722 | $12.6M | 0.03% | New |
| 18 | Simplify Asset Management#18 · 1,432,105 sh | 1,432,105 | $9.4M | 0.13% | +20.9% |
| 19 | WELLINGTON MANAGEMENT GROUP LLP#19 · 1,426,915 sh | 1,426,915 | $9.3M | <0.01% | New |
| 20 | LPL Financial#20 · 902,255 sh | 902,255 | $5.9M | <0.01% | +23.9% |
| 21 | NORTHERN#21 · 743,760 sh | 743,760 | $4.9M | <0.01% | +230.9% |
| 22 | Spruce Street Capital#22 · 736,637 sh | 736,637 | $4.8M | 0.94% | New |
| 23 | VANGUARD FIDUCIARY#23 · 593,751 sh | 593,751 | $3.9M | <0.01% | +87.8% |
| 24 | RAYMOND JAMES FINANCIAL#24 · 546,318 sh | 546,318 | $3.6M | <0.01% | -14.9% |
| 25 | VANGUARD PORTFOLIO MANAGEMENT#25 · 537,596 sh | 537,596 | $3.5M | <0.01% | New |
| 26 | KVP Capital Advisors#26 · 462,355 sh | 462,355 | $3.0M | 2.22% | 0.0% |
| 27 | TWO SIGMA INVESTMENTS#27 · 441,187 sh | 441,187 | $2.9M | <0.01% | -25.0% |
| 28 | UBS Group AG#28 · 313,004 sh | 313,004 | $2.0M | <0.01% | -4.1% |
| 29 | CHARLES SCHWAB INVESTMENT MANAGEMENT#29 · 232,138 sh | 232,138 | $1.5M | <0.01% | +439.9% |
| 30 | Caption Management#30 · 227,733 sh | 227,733 | $1.5M | <0.01% | New |
| 31 | SILVERARC CAPITAL MANAGEMENT#31 · 227,178 sh | 227,178 | $1.5M | 0.15% | New |
| 32 | Bank of New York Mellon#32 · 218,126 sh | 218,126 | $1.4M | <0.01% | New |
| 33 | Nuveen#33 · 191,150 sh | 191,150 | $1.2M | <0.01% | New |
| 34 | BANK OF AMERICA#34 · 185,075 sh | 185,075 | $1.2M | <0.01% | +161.8% |
| 35 | RENAISSANCE TECHNOLOGIES#35 · 178,049 sh | 178,049 | $1.2M | <0.01% | +537.0% |
| 36 | WELLS FARGO & COMPANY#36 · 170,633 sh | 170,633 | $1.1M | <0.01% | +67.3% |
| 37 | CITADEL ADVISORS#37 · 123,129 sh | 123,129 | $804.0K | <0.01% | New |
| 38 | CANTOR FITZGERALD, L. P.#38 · 121,631 sh | 121,631 | $794.3K | <0.01% | New |
| 39 | BNP PARIBAS FINANCIAL MARKETS#39 · 121,215 sh | 121,215 | $791.5K | <0.01% | New |
| 40 | Shay Capital#40 · 92,810 sh | 92,810 | $606.0K | 0.04% | -54.8% |
| 41 | XTX Topco Ltd#41 · 90,030 sh | 90,030 | $587.9K | <0.01% | +394.2% |
| 42 | RHUMBLINE ADVISERS#42 · 87,023 sh | 87,023 | $568.3K | <0.01% | New |
| 43 | Ronald Blue#43 · 85,888 sh | 85,888 | $560.8K | — | 0.0% |
| 44 | Diametric Capital#44 · 81,179 sh | 81,179 | $530.1K | 0.06% | +335.3% |
| 45 | DEUTSCHE BANK AG\#45 · 77,485 sh | 77,485 | $506.0K | <0.01% | New |
| 46 | CITIGROUP#46 · 74,114 sh | 74,114 | $484.0K | <0.01% | +1260.4% |
| 47 | MANCHESTER FINANCIAL#47 · 67,177 sh | 67,177 | $438.7K | — | +1.4% |
| 48 | MEMBERS WEALTH#48 · 66,763 sh | 66,763 | $436.0K | — | +122.5% |
| 49 | PRICE T ROWE ASSOCIATES#49 · 64,769 sh | 64,769 | $423.0K | 0.00% | New |
| 50 | MORGAN STANLEY#50 · 59,374 sh | 59,374 | $387.7K | 0.00% | -15.6% |
| 51 | Virtus Investment Advisers#51 · 59,275 sh | 59,275 | $387.1K | 0.09% | New |
| 52 | ADAR1 Capital Management#52 · 53,800 sh | 53,800 | $351.3K | 0.02% | +12.6% |
| 53 | JANE STREET GROUP#53 · 50,456 sh | 50,456 | $329.5K | 0.00% | -71.4% |
| 54 | MetLife Investment Management#54 · 45,985 sh | 45,985 | $300.3K | <0.01% | New |
| 55 | OSAIC#55 · 43,115 sh | 43,115 | $281.5K | <0.01% | -23.2% |
| 56 | WINTON GROUP Ltd#56 · 42,500 sh | 42,500 | $277.5K | <0.01% | New |
| 57 | Invesco Ltd.#57 · 42,292 sh | 42,292 | $276.2K | 0.00% | New |
| 58 | GOLDMAN SACHS GROUP#58 · 40,976 sh | 40,976 | $267.6K | 0.00% | -73.2% |
| 59 | MIRAE ASSET GLOBAL ETFS Ltd.#59 · 40,050 sh | 40,050 | $260.2K | <0.01% | New |
| 60 | Rafferty Asset Management#60 · 37,521 sh | 37,521 | $245.0K | <0.01% | New |
| 61 | Next Capital Management#61 · 34,995 sh | 34,995 | $228.5K | 0.06% | 0.0% |
| 62 | AMERIFLEX GROUP#62 · 33,598 sh | 33,598 | $219.4K | 0.09% | New |
| 63 | Vanguard Global Advisers#63 · 32,408 sh | 32,408 | $211.6K | <0.01% | +43.4% |
| 64 | JPMORGAN CHASE#64 · 32,289 sh | 32,289 | $201.2K | 0.00% | New |
| 65 | SUSQUEHANNA INTERNATIONAL GROUP, LLP#65 · 30,372 sh | 30,372 | $198.3K | 0.00% | -92.1% |
| 66 | Rockefeller Capital Management L.P.#66 · 30,000 sh | 30,000 | $195.9K | <0.01% | 0.0% |
| 67 | Jones Hill Capital#67 · 26,760 sh | 26,760 | $174.7K | 0.04% | New |
| 68 | BCV Asset Management#68 · 26,365 sh | 26,365 | $164.6K | <0.01% | 0.0% |
| 69 | AXQ CAPITAL#69 · 25,173 sh | 25,173 | $164.4K | 0.02% | +65.6% |
| 70 | Robertson Stephens Wealth Management#70 · 25,000 sh | 25,000 | $163.3K | — | +25.0% |
| 71 | Keating Financial Advisory Services#71 · 24,911 sh | 24,911 | $162.7K | 0.02% | 0.0% |
| 72 | Police & Firemen's Retirement System of New Jersey#72 · 22,958 sh | 22,958 | $149.9K | <0.01% | New |
| 73 | ALLIANCEBERNSTEIN L.P.#73 · 48,940 sh | 48,940 | $143.9K | 0.00% | New |
| 74 | Scientech Research#74 · 22,007 sh | 22,007 | $143.7K | 0.12% | +1.3% |
| 75 | MANUFACTURERS LIFE INSURANCE COMPANY, THE#75 · 20,610 sh | 20,610 | $134.6K | <0.01% | New |
| 76 | SEI INVESTMENTS#76 · 20,500 sh | 20,500 | $133.9K | <0.01% | New |
| 77 | BARCLAYS PLC#77 · 19,994 sh | 19,994 | $130.6K | 0.00% | -58.4% |
| 78 | PROFUND ADVISORS#78 · 19,856 sh | 19,856 | $129.7K | <0.01% | New |
| 79 | NEW YORK STATE COMMON RETIREMENT FUND#79 · 19,200 sh | 19,200 | $125.4K | <0.01% | New |
| 80 | nVerses Capital#80 · 18,201 sh | 18,201 | $118.9K | 0.18% | +28.2% |
| 81 | FMR#81 · 17,707 sh | 17,707 | $115.6K | 0.00% | +200.4% |
| 82 | MAGNOLIA CAPITAL ADVISORS#82 · 15,100 sh | 15,100 | $98.6K | 0.02% | -37.3% |
| 83 | VOYA INVESTMENT MANAGEMENT#83 · 14,844 sh | 14,844 | $96.9K | <0.01% | New |
| 84 | SBI Securities , Ltd.#84 · 14,841 sh | 14,841 | $96.9K | — | +5.2% |
| 85 | INTECH INVESTMENT MANAGEMENT#85 · 13,736 sh | 13,736 | $89.7K | <0.01% | New |
| 86 | StoneX Group#86 · 16,342 sh | 16,342 | $86.5K | <0.01% | New |
| 87 | PRUDENTIAL FINANCIAL#87 · 13,040 sh | 13,040 | $85.2K | <0.01% | New |
| 88 | Alpine Global Management#88 · 12,500 sh | 12,500 | $81.6K | 0.01% | -75.0% |
| 89 | ROYAL BANK OF CANADA#89 · 12,376 sh | 12,376 | $81.0K | 0.00% | +9722.2% |
| 90 | Windsor Capital Management#90 · 10,817 sh | 10,817 | $70.6K | — | 0.0% |
| 91 | ProShare Advisors#91 · 10,192 sh | 10,192 | $66.6K | <0.01% | New |
| 92 | Legal & General Group Plc#92 · 7,555 sh | 7,555 | $49.3K | 0.00% | New |
| 93 | Ameritas Investment Partners#93 · 7,064 sh | 7,064 | $46.1K | <0.01% | New |
| 94 | Russell Investments Group, Ltd.#94 · 6,374 sh | 6,374 | $41.6K | 0.00% | +4149.3% |
| 95 | Allworth Financial#95 · 3,000 sh | 3,000 | $19.6K | <0.01% | 0.0% |
| 96 | Tower Research Capital (TRC)#96 · 2,994 sh | 2,994 | $19.6K | <0.01% | New |
| 97 | Persistent Asset Partners Ltd#97 · 2,780 sh | 2,780 | $18.2K | <0.01% | New |
| 98 | Steward Partners Investment Advisory#98 · 2,432 sh | 2,432 | $15.9K | <0.01% | +1031.2% |
| 99 | FIFTH THIRD BANCORP#99 · 2,290 sh | 2,290 | $15.0K | 0.00% | 0.0% |
| 100 | Federation des caisses Desjardins du Quebec#100 · 2,000 sh | 2,000 | $13.1K | 0.00% | 0.0% |
Funds that sold out of ACHV in Q2 2026 (17)
Held ACHV at the end of Q1 2026 and filed a Q2 2026 13F without it. Not in the list above, because they no longer hold it. Largest prior position first.
| Institution | Shares sold | Value in Q1 2026 |
|---|---|---|
| MILLENNIUM MANAGEMENT2,154,676 sh | 2,154,676 | $3.2M |
| Nantahala Capital Management1,297,770 sh | 1,297,770 | $1.9M |
| 683 Capital Management400,000 sh | 400,000 | $588.0K |
| Lakeside Advisors222,202 sh | 222,202 | $326.6K |
| Hudson Bay Capital Management169,792 sh | 169,792 | $249.6K |
| Brevan Howard Capital Management109,016 sh | 109,016 | $160.3K |
| DIMENSIONAL FUND ADVISORS104,840 sh | 104,840 | $154.1K |
| Point72 Asset Management, L.P.75,520 sh | 75,520 | $111.0K |
| HRT FINANCIAL63,158 sh | 63,158 | $92.0K |
| Goldstone Financial Group48,326 sh | 48,326 | $71.0K |
| Squarepoint Ops39,316 sh | 39,316 | $57.8K |
| Catalyst Funds Management Pty Ltd36,000 sh | 36,000 | $52.9K |
| Schonfeld Strategic Advisors28,778 sh | 28,778 | $42.3K |
| LEUCADIA NATIONAL25,144 sh | 25,144 | $37.0K |
| Foundations Investment Advisors23,404 sh | 23,404 | $34.4K |
| Madison Park Capital Advisors20,000 sh | 20,000 | $29.4K |
| SLT19,000 sh | 19,000 | $27.9K |
Source: Form 13F-HR filings on SEC EDGAR, Q2 2026. Values are as reported by each manager at quarter end. “% of portfolio” is the position’s share of the manager’s total reported 13F value for the same quarter. “New” means the manager filed a 13F for Q1 2026 without this position; a dash means no comparison is available. Where a manager’s own filing is internally inconsistent its value is withheld and it is listed last. 13F data shows reported holdings, not recommendations.